Impaired glucose tolerance

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Information
Disease name
Impaired glucose tolerance
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04341571 Active, not recruiting Phase 2 Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes. October 24, 2019 December 2024
NCT05056376 Active, not recruiting N/A Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs October 1, 2021 June 30, 2025
NCT03938389 Active, not recruiting Phase 4 The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans February 25, 2020 June 2024
NCT01864460 Active, not recruiting N/A Improving Autonomic Function and Balance in Diabetic Neuropathy November 14, 2013 November 30, 2026
NCT00140647 Completed Phase 3 The Study of Atherosclerosis With Ramipril and Rosiglitazone July 2001 July 2006
NCT00218998 Completed N/A Effective Endurance Training in Metabolic Syndrome January 2004
NCT00220441 Completed Phase 2 Cognitive Effects of Aerobic Exercise for IGT Adults July 2004 April 2008
NCT00220961 Completed Phase 3 Actos Now for Prevention of Diabetes (ACT NOW) January 2004 April 2010
NCT00241072 Completed Phase 4 Clinical Trial To Evaluate The Effect Of Valsartan On Insulin Sensitivity In Subjects With Impaired Glucose Tolerance September 2002 July 2005
NCT00352287 Completed Phase 4 Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults March 2003 April 2005
NCT00370305 Completed Phase 2 11ß-HSD1 and Metabolic Syndrome May 2004 October 2008
NCT00381186 Completed N/A Impact of 3-year Lifestyle Intervention on Postprandial Glucose Metabolism: the SLIM Study February 1999 June 2006
NCT00402194 Completed N/A Treating the Endothelium to Restore Insulin Sensitivity June 2005 March 2012
NCT00407862 Completed Phase 4 Telmisartan and Losartan in Hypertensive IGT January 2005 June 2006
NCT00413335 Completed N/A Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth November 2005 December 2008
NCT00456885 Completed Phase 4 The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women April 2007 September 2010
NCT00476710 Completed Effects of Colesevelam HCl On Bile Acid Kinetics May 2007 April 2009
NCT00489229 Completed Phase 3 To Investigate the Effect of Rosiglitazone and Ramipril on Pre-clinical Vasculopathy in Diabetes and IGT Patients October 2002 December 2005
NCT00510588 Completed N/A Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease July 2007 October 2013
NCT00536250 Completed Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth September 2001 March 2017
NCT00546728 Completed Phase 4 The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes October 2007 July 2011
NCT00564551 Completed N/A Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance October 2007 October 2009
NCT00573781 Completed Phase 2 Dietary Modulation of Gene Expression and Metabolic Pathways in Glucose Metabolism September 2007 June 2009
NCT00594399 Completed Phase 2/Phase 3 Enhancing Fitness in Older Pre-diabetic Veterans October 2008 June 2011
NCT00625781 Completed N/A Treatment of Impaired Glucose Tolerance in Pregnancy February 2008 December 2013
NCT00627744 Completed Phase 4 Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction May 2008 November 2010
NCT00652379 Completed N/A Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients June 2008 May 2011
NCT00663000 Completed Glucose Tolerance in Acromegaly: The Influence of GH-excess on Glucose Metabolism and Insulin Resistance April 2008 December 2012
NCT00675740 Completed Phase 4 Physical Exercise Versus Rosiglitazone in CAD and Prediabetes January 2004 February 2007
NCT00685594 Completed Phase 2/Phase 3 Vitamin D for the Prevention of Diabetes Type 2 March 2008 September 2015
NCT00722631 Completed N/A Anti-Inflammatory Effects of Pioglitazone May 2007 April 2012
NCT02987595 Completed N/A Effects of Lignan-rich Diet on Cardiometabolic Risk Factors June 2015 October 2016
NCT00095654 Completed Phase 3 The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial July 2001 October 2006
NCT00116922 Completed Phase 3 A Lifestyle and Combination Medication Therapy Diabetes Prevention Study June 2004 January 2010
NCT00122447 Completed N/A Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance May 2005 May 2011
NCT01386645 Completed N/A Effect of Dietary Glycemic Index on Beta-cell Function July 2011 August 1, 2019
NCT01406665 Completed Skin Autofluorescence (AF) Decision Tree in Detecting Impaired Glucose Tolerance (IGT) or Diabetes Mellitus (DM) October 2010 April 2011
NCT01414647 Completed N/A The Health Effect of Diet Rich in Nordic Berries January 2006 March 2010
NCT01420198 Completed N/A Efficiency and Cost-effectiveness of a Culturally Adopted Lifestyle Intervention Program - the MEDIM Study. January 2015 June 2015
NCT01425905 Completed Phase 2 Mood and Insulin Resistance in Adolescents At-Risk for Diabetes August 23, 2011 August 10, 2015
NCT01488279 Completed N/A Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy September 2012 December 2015
NCT01521312 Completed Phase 2 ACute and Chronic Effects of Saxagliptin September 2012 September 2014
NCT01559896 Completed N/A Egg Protein Hydrolysate and Vascular Function September 2011 November 2013
NCT01593605 Completed N/A Resveratrol-Leucine Metabolite Synergy in Pre-diabetes February 2012 June 2013
NCT01741467 Completed N/A The Effect of Real Time Continuous Glucose Monitoring in Subjects With Pre-diabetes May 2012 August 2016
NCT01754792 Completed N/A Effects of Pinitol on Hidrocarbonated Metabolism Parameters in Diabetic, Impaired and Normal Fasting Glucose Subjects January 2012 July 2013
NCT01771380 Completed Measurement of the Free Fraction of 25-hydroxyvitamin D in Serum February 2013 August 2015
NCT01961674 Completed N/A Studying the Effect of Capsinoids on Brown Fat Using Infrared Thermal Imaging. November 2013 July 2014
NCT01993927 Completed Voglibose Tablets 0.2 / OD Tablets 0.2 Special Drug Use Surveillance "Long-term Use in Patients With Impaired Glucose Tolerance" November 18, 2009 August 31, 2013
NCT02066948 Completed N/A Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health January 2014 November 2015
NCT02135172 Completed N/A Breaks in Sedentary Time and Glucose Regulation in Women October 2013 November 2014
NCT02151188 Completed N/A Liquid Protein Preloads With Different Carbohydrate Types Effects on the Glycaemic and Insulinaemic Response March 2014 October 2015
NCT02158481 Completed N/A Effects of Dietary Ingredients on Vascular Function April 2014 December 2014
NCT02248272 Completed N/A Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes October 2011 September 2013
NCT02254317 Completed N/A Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance September 15, 2014 July 1, 2015
NCT02455934 Completed N/A Effects of D-allulose (Psicose) With Sucrose Beverage on Glucose Tolerance and Insulin Level April 2015 December 2015
NCT02569762 Completed N/A Effects of Artificial Sweeteners on Gut Microbiota and Glucose Metabolism July 2016 January 2018
NCT02621060 Completed Phase 2 Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance September 2015 February 2016
NCT02700334 Completed Phase 4 Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes October 2016 February 2017
NCT02708966 Completed Phase 2 Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance. March 2016 October 2018
NCT02800707 Completed N/A Sucralose, Stevia, Gut Microbiome and Glucose Metabolism January 3, 2017 January 31, 2018
NCT02808182 Completed N/A Postprandial Fatty Acid Metabolism in the Natural History of Type 2 Diabetes (T2D) January 17, 2017 May 2021
NCT02896010 Completed N/A Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes October 10, 2016 November 17, 2017
NCT02907190 Completed N/A Glycemic and Insulinemic Impact of Selected Canadian Beans March 2016 September 2016
NCT02938091 Completed N/A Dietary Modulation of Hepatic Lipase (LIPC) -514 C/T Variant Associations With Lipids and Glucose January 2008 July 2012
NCT00067626 Completed Phase 2 Chromium Effects on Insulin and Vascular Function in People at Risk for Diabetes April 2005 March 2009
NCT03316690 Completed N/A The Interaction Between Metformin and Physical Training October 20, 2017 October 1, 2018
NCT03329651 Completed N/A The Interaction Between Metformin and Acute Exercise November 10, 2017 October 1, 2018
NCT03419702 Completed N/A Almonds and Health Effects on Metabolism, Vascular Function and Cognition January 10, 2018 December 3, 2021
NCT03650023 Completed N/A A Crossover Trial of Chitosan Oligosaccharide on Post Prandial Glucose Control in Subjects With Normal, IFG and IGT May 9, 2018 July 25, 2018
NCT03725033 Completed Phase 3 Clinical Trial of Efficacy and Safety of Subetta in the Treatment of Impaired Glucose Tolerance October 10, 2018 March 23, 2020
NCT03764423 Completed N/A Health Effects of Salmon Fishmeal in Humans September 14, 2018 November 1, 2019
NCT03945435 Completed Mechanisms of Exercise Resistance in Metabolic Disease July 1, 2018 April 11, 2019
NCT04088461 Completed Phase 4 Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine September 2016 September 2018
NCT04283201 Completed Phase 2 Type 2 Diabetes Mellitus Prevention Ukraine February 20, 2020 December 31, 2021
NCT04529473 Completed N/A Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control February 3, 2021 August 23, 2022
NCT05215210 Completed N/A The Effect of Long-term Momordica Charantia Supplementation on Blood Glucose Levels March 23, 2022 June 30, 2022
NCT05493553 Completed N/A Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability August 8, 2022 September 29, 2022
NCT00829660 Completed Phase 4 Acarbose Cardiovascular Evaluation Trial February 17, 2009 April 18, 2017
NCT00841867 Completed The Role of Pulsatile Insulin Secretion (A Study Investigating the Effects of Partial Pacreatectomy on Glucose Metabolism) December 2008 October 2009
NCT00845182 Completed Phase 4 Effect of Pioglitazone and Exenatide on Body Weight and Beta Cell Function June 2007 July 2010
NCT00847899 Completed Phase 2 Evaluation of Soluble Epoxide Hydrolase (s-EH) Inhibitor in Patients With Mild to Moderate Hypertension and Impaired Glucose Tolerance January 2009 November 2009
NCT00917449 Completed Phase 3 Prevention of Type 2 Diabetes Mellitus by L-Arginine in Patients With Metabolic Syndrome December 2005 June 2009
NCT00951639 Completed N/A Cassia Cinnamon for Glucose Uptake in Young Women February 2008 May 2009
NCT00974272 Completed Phase 4 Effects of Exenatide on Postprandial Hyperlipidemia and Inflammation August 2006 November 2008
NCT00992641 Completed N/A The Effect of Nordic Recommended Diet on the Features of Metabolic Syndrome - Multicentre Study August 2009 December 2011
NCT01020578 Completed Low Density Lipoprotein (LDL) Cholesterol Metabolism in Impaired Glucose Tolerance June 2008 October 2009
NCT01030861 Completed Phase 2 Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk" August 2010 June 2019
NCT01030978 Completed N/A Prevention of Type 2 Diabetes in Children With a Family-based Healthy Lifestyle Program September 2009 September 2011
NCT01034826 Completed Progression to Impaired Glucose Tolerance and Type 2 Diabetes in the Korean People-based KNDP Study February 2007 May 2010
NCT01068860 Completed Phase 2 To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies February 2010 August 2010
NCT01094418 Completed Electrodiagnostic Parameters in Patients With Impaired Glucose Tolerance and Diabetes Mellitus June 2009 February 2010
NCT01219231 Completed Phase 4 Effects of Physical Activity on the Brain in Impaired Glucose Tolerance (IGT) August 2010 January 2015
NCT01234649 Completed Phase 3 Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM) August 11, 2011 June 14, 2019
NCT01275469 Completed Phase 2 Pilot Study With GFT505 (80mg) in Patients Presenting With Impaired Glucose Tolerance and Abdominal Obesity. June 2009 January 2010
NCT01339637 Completed Evaluation of Low Source of Signal in SCOUT DS April 2011 October 2011
NCT01346254 Completed Phase 2 Glucose Control in Pre-Diabetic Renal Transplant Patients December 2009 November 2011
NCT01375660 Completed N/A D Vitamin Intervention in VA May 2011 November 2014
NCT01375959 Completed N/A Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance April 2011 April 2015
NCT01385995 Completed Phase 2 Effects of Treatment of Sleep Apnea on Metabolic Syndrome January 2004 September 2008
NCT05914857 Not yet recruiting Phase 2 Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients December 20, 2023 December 1, 2025
NCT04018105 Not yet recruiting N/A Influence of Preprandial Metformin Administration on Carbohydrate Absorption December 2022 December 2024
NCT05628584 Not yet recruiting N/A High FODMAP Diet With Metformin in preDM November 15, 2022 October 15, 2023
NCT05387551 Recruiting N/A CGM and Lifestyle Changes in Patients With Impaired Glucose Tolerance December 1, 2022 March 31, 2025
NCT02953834 Recruiting Phase 1 Kisspeptin Influence on Glucose Homeostasis July 18, 2017 August 2024
NCT05347030 Recruiting N/A Acupuncture for Impaired Glucose Tolerance in Overweight/Obese Population October 6, 2022 December 31, 2024
NCT05354245 Recruiting N/A Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL) September 8, 2022 December 2024
NCT05912348 Recruiting N/A The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults February 8, 2023 January 1, 2026
NCT05873322 Recruiting Glucose Intolerance and Diabetes Related to Treatment With Steroids and PEG- Asparaginase in Children and Adolescents With ALL and Lymphoma August 30, 2022 December 31, 2025
NCT05067621 Recruiting Phase 2 Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease July 17, 2023 January 2027
NCT05951270 Terminated N/A Glucose Homeostasis and Apple Polyphenols January 14, 2022 February 3, 2023
NCT00212017 Terminated N/A Assessment of an Alpha-glucosidase Inhibitor to Block Cardiac Events in Patients With MI and IGT April 2005 August 2017
NCT00510705 Terminated N/A Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease July 2007
NCT00846521 Terminated Phase 4 Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity September 2006 September 2008
NCT01409993 Terminated Phase 4 Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis August 2011 November 2016
NCT05412264 Terminated N/A Step Up For Health Study: A Pedometer and Website Intervention in Those With Prediabetes January 2014 July 20, 2021
NCT01548651 Terminated Phase 4 Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation February 2012 August 25, 2017
NCT01468376 Terminated Phase 1 GLU-xx Formulations in Individuals With Impaired Glucose Tolerance February 2011 January 2012
NCT01933529 Unknown status Phase 2 ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes) October 2013 December 2015
NCT00733174 Unknown status Phase 4 Rosiglitazone Therapy In The Prevention Of Coronary Artery Disease In Patients With Impaired Glucose Tolerance March 2004
NCT03029390 Unknown status Phase 4 Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes March 2016 December 2023
NCT00852982 Unknown status N/A Exercise Effects on Cardiovascular Risk Factors, Quality of Life, Muscle Function in Type 2 Diabetes and Healthy Persons April 2006 September 2009
NCT00858676 Unknown status Phase 4 Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial) April 2009 March 2013
NCT00926133 Unknown status Type 2 Diabetes and Acute Myocardial Infarction November 2005 December 2009
NCT05202002 Unknown status N/A Decrease Type II Diabetes in Gestational Diabetes Population March 1, 2021 May 30, 2023
NCT00961363 Unknown status Phase 2 Effect of Sitagliptin in Impaired Glucose Tolerance December 2009
NCT01841229 Unknown status Effect of Ginseng on Glycemic Control October 2012 May 2013
NCT00724542 Unknown status N/A Evaluation of Intervention on Impaired Glucose Tolerance(IGT) in Patients With Coronary Heart Disease. July 2008 December 2010
NCT03343262 Unknown status N/A Mechanisms Underlying the Regulation of Impaired Glucose Tolerance by Auricular Concha Electro-acupuncture January 1, 2018 December 31, 2020
NCT03383068 Unknown status Phase 4 Research of Intensive Metabolic Intervention Before Pregnancy in PCOS January 1, 2018 June 30, 2020
NCT01149005 Unknown status N/A Cystic Fibrosis (CF) Exacerbation and Insulin Treatment June 2010 December 2015
NCT00472342 Unknown status N/A The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients March 2007 December 2007
NCT01330550 Unknown status N/A Effect of High Fiber and Sugar Free Biscuits in Prediabetics Population March 2011 December 2011
NCT01364155 Unknown status Phase 2 Safety, Tolerability, PK, and PD of LIM-0705 in Subjects With Impaired Glucose Tolerance or Abnormal HOMA-IR May 2011 August 2011
NCT00417950 Unknown status N/A Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes January 2007
NCT04662866 Unknown status Phase 2 Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose February 10, 2021 October 2023
NCT02848053 Unknown status The Long-term Effect of Tianqi Capsule Interventions to Prevent Diabetes in the REDUCES Study: a 8-year Follow-up Study August 2016 November 2016
NCT04727580 Unknown status Phase 2 HSK7653 in Chinese Patients With Impaired Glucose Tolerance March 29, 2021 June 28, 2022
NCT04938843 Unknown status N/A Effect of F. Prausnitzii on Glycemic Control August 16, 2021 December 31, 2023
NCT02472717 Withdrawn Phase 2 Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study May 2015 October 2016
NCT01093677 Withdrawn Phase 1 Investigation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LIM-0705 in Male Subjects With Impaired Glucose Tolerance March 2010 July 2010
NCT00845559 Withdrawn Phase 4 The Effects of Exenatide on Post-Meal Sugar Peaks and Vascular Health in Obese/Pre-Diabetic Young Adults August 2008
NCT03315663 Withdrawn N/A Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study July 1, 2017 April 19, 2019