Annotation Detail

Information
Associated Genes
IFNG
Associated Variants
IFNG MUTATION
IFNG MUTATION
Associated Disease
arteriosclerosis
Source Database
DisGeNET
Description
The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-TLR4 cross-talk plays a crucial role in coronary and carotid artery plaque development and identifies a STAT1-dependent gene signature that could represent a novel diagnostic tool to monitor and diagnose plaque progression in human atherosclerosis.
Pubmed
25196434
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.0111589113202849
Drugs