Cancer of Head and Neck

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Information
Disease name
Cancer of Head and Neck
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04356170 Active, not recruiting Phase 2 Trial Evaluating Adapted Chemotherapy in Patients With Squamous Carcinoma February 4, 2021 July 2025
NCT02573493 Active, not recruiting Phase 2 Nab-Paclitaxel and Cisplatin or Nab-paclitaxel as Induction Therapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (HNSCC) April 13, 2016 December 12, 2024
NCT04617678 Active, not recruiting N/A A Comprehensive Approach to Head and Neck Cancer Prehabilitation October 21, 2021 December 2024
NCT05061316 Active, not recruiting N/A The Gut Microbiome as an Indicator of Readiness for Head & Neck Cancer Surgery March 11, 2022 January 1, 2026
NCT02296684 Active, not recruiting Phase 2 Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma March 25, 2015 December 31, 2025
NCT00343083 Completed Phase 2 Evaluation of Cetuximab (ERBITUX) and Concurrent Carboplatin, Paclitaxel & Radiotherapy in the Management of Patients With Advanced Locoregional Squamous Cell Carcinomas of the Head and Neck (GCC 0442) December 2004 May 2012
NCT00798655 Completed Phase 2 Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer November 2007 November 9, 2016
NCT01059643 Completed Phase 2 A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck April 2011 December 2012
NCT01116336 Completed Phase 1 Phase I Chemoprevention Trial With Green Tea Polyphenon E & Erlotinib in Patients With Premalignant Lesions of the Head & Neck March 2010 May 2018
NCT01235052 Completed N/A Prognostic Evaluation of 18fmiso Pet-ct in Head and Neck Cancer June 2009 July 2014
NCT05269342 Completed N/A Nurse-led Exercise Improves Shoulder Pain, Shoulder Disability, and Quality of Life in Head and Neck Cancer September 14, 2017 September 9, 2018
NCT01317589 Completed Phase 4 Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective? May 2011 July 2015
NCT01584284 Completed Phase 1 Safety Study of Attenuated Vaccinia Virus (GL-ONC1)With Combination Therapy in Head & Neck Cancer April 2012 July 2015
NCT01681654 Completed N/A Exercise and Nutrition for Head and Neck Cancer Patients June 2012 December 2014
NCT01853670 Completed N/A Adaptive Radiation Therapy for Head & Neck Cancer Patients August 2009 January 2015
NCT01885065 Completed N/A Efficacy of Novel Edible Gel-based Artificial Saliva in Cancer Patients July 2012 December 2012
NCT01998542 Completed Phase 2 Safety and Tolerability Study of AlloVax(TM) in Patients With Metastatic or Recurrent Cancer of the Head and Neck January 2016 November 2017
NCT02030509 Completed Quick Diagnostic Program for Head and Neck Cancer February 2014 May 2016
NCT02053428 Completed N/A Comparison of Percutaneous Image-guided Gastrostomies June 2013 October 2014
NCT02075112 Completed Phase 1 Soy Isoflavone in Combination With Radiation Therapy and Cisplatin in SCC of the Head and Neck November 2013 September 2019
NCT02366611 Completed N/A Pain Control Using Neuromodulation in Patients Undergoing Definitive Chemoradiotherapy for Head and Neck Cancer November 2014 November 2019
NCT02372890 Completed Validation of High-resolution PET/CT for the Pretherapeutic Lymphnode Staging of Head/Neck Cancer July 2012 December 31, 2017
NCT02450305 Completed Hyperbaric Oxygen and Its Effect on Radiation Induced Long Term Side Effects August 2013 January 19, 2022
NCT04554667 Completed Phase 1 Heavy Lifting Strength Training in Head and Neck Cancer Survivors November 24, 2020 July 31, 2022
NCT00038584 Completed Phase 1 A Phase IB Study Of Oral SCH 66336 Preoperatively In Patients With Head And Neck Squamous Cell Cancer June 1999 November 2004
NCT02627274 Completed Phase 1 A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C) December 7, 2015 November 10, 2022
NCT02648178 Completed N/A Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers June 2016 May 2018
NCT02780765 Completed N/A Study to Compare the Effect of Two Different Types of Humidifier on the Endotracheal Tube Patency July 2016 January 2017
NCT03841175 Completed Forecasts Impact of the Pre-therapeutic TEP-TDM in the 18-FDG Restaging of Upper Aero-digestive Tract Cancers May 1, 2018 August 1, 2018
NCT03574870 Completed N/A Wearable Sensor for Biometrics During Locoregional Therapy for Head and Neck Cancer October 30, 2017 December 31, 2019
NCT03821064 Completed N/A Single-arm Phase II Study of NDURE for Patients With HNC June 3, 2019 November 21, 2019
NCT00255476 Completed Phase 2 The IRESSA Novel Head and Neck Chemotherapy Evaluation Study February 2004 July 2007
NCT00318890 Completed Phase 1/Phase 2 Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck October 2002 December 2007
NCT03569436 Completed Effectiveness and Safety of Nivolumab in Participants That Have Head and Neck Cancer That Has Come Back or Has Spread February 14, 2018 June 26, 2020
NCT02865135 Completed Phase 1/Phase 2 Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer March 30, 2017 February 6, 2023
NCT02869399 Completed N/A Tertiary Prevention of Head and Neck Cancer With a Dietary Intervention November 2015 February 2023
NCT04314349 Completed Radiogenomics in Aerodigestive Tract Cancers August 1, 2020 December 31, 2023
NCT02900911 Completed N/A Swallowing Rehabilitation in Patients With Head and Neck Cancer Receiving Radiotherapy May 2016 May 2020
NCT03086629 Completed N/A Improving Quality of Life Through the Routine Use of the Patient Concerns Inventory for Head and Neck Cancer Patients January 2017 June 30, 2020
NCT04189107 Completed Phase 3 Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS August 18, 2020 November 9, 2022
NCT03378193 Completed Prognostic Value of 18FDG PET/CT Textural Indices in HNSCC January 1, 2018 March 30, 2018
NCT00242749 Completed Phase 2 IRESSA in Combination With Cisplatin & Radiotherapy in Patients With Advanced Head & Neck Carcinoma December 2002 July 2007
NCT03419741 Completed N/A Brain Stimulation For Cancer Smokers October 21, 2017 October 20, 2020
NCT04800419 Not yet recruiting N/A RCT of Acceptance and Commitment Therapy Versus Mindfulness-based Stress Reduction in Head and Neck Cancer July 1, 2021 June 30, 2024
NCT05482841 Recruiting Lung Ultrasound Score After ENT Cancer Surgery December 1, 2022 January 2025
NCT02557048 Recruiting Head and Neck Cancer in Children: A Retrospective Study January 10, 2019 December 2023
NCT03383094 Recruiting Phase 2 Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer March 15, 2018 June 2025
NCT03894553 Recruiting N/A Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain June 22, 2020 August 31, 2024
NCT03993353 Recruiting Phase 2 Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer April 7, 2020 March 1, 2029
NCT04258813 Recruiting N/A Onco-primary Care Networking to Support TEAM-based Care June 14, 2021 December 31, 2024
NCT04510129 Recruiting A Multicenter Cancer Biospecimen Collection Study February 5, 2020 February 2027
NCT04658342 Recruiting Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing April 16, 2021 December 2024
NCT04767048 Recruiting Phase 2 Interest of Bilateral Basic Tongue Mucosectomy Assisted by Robot or Laser in Combination With Tonsillectomy in the Assessment of Prevalent Cervical Lymphadenopathy June 30, 2021 March 2029
NCT05179824 Recruiting Tempus Priority Study: A Pan-tumor Observational Study October 19, 2020 October 19, 2030
NCT05316974 Recruiting Lymphoedema Among Persons With Head- and Neck Cancer October 1, 2022 December 31, 2024
NCT01284348 Terminated Phase 2 To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung Cancer March 25, 2011 September 21, 2012
NCT00200408 Terminated Assessment of Early Genetic Changes in Smokers March 2004
NCT02402348 Terminated Early Phase 1 Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis December 2014 August 2016
NCT03682367 Terminated Phase 3 Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery December 1, 2018 April 6, 2020
NCT02892487 Terminated N/A Evaluation of an Active Swallowing Rehabilitation on Quality of Life of Patients Treated by Radiotherapy for Head and Neck Cancer December 9, 2016 June 2021
NCT03193931 Terminated Phase 2 Study Comparing Pembrolizumab With Methotrexate in Elderly, Frail or Cisplatin-ineligible Patients With Head and Neck Cancers February 2, 2018 March 23, 2022
NCT03760471 Unknown status N/A Palliative and Oncology Care Intervention: Symptom COACH November 7, 2018 November 2022
NCT02832102 Unknown status Big Data and Models for Personalized Head and Neck Cancer Decision Support (BD2Decide) April 2016 April 2019
NCT02528955 Unknown status Phase 2 De-Intensification Radiotherapy Postoperative Head Neck October 2014 October 2021
NCT02441972 Unknown status Phase 1 Clinic Study of 18F-Al-NOTA-PRGD2 in Cancer Diagnostics January 2012 December 2020
NCT03558594 Unknown status N/A Hypnosis and Meditation for Cancer Pain July 31, 2018 July 28, 2020
NCT03954691 Unknown status Targeting Potassium Channels to Reprogram Glioblastoma Microenvironment: in Vitro and in Vivo Studies October 1, 2019 October 1, 2021
NCT04804852 Unknown status Assessment of the Prevalence of Sarcopenia by CT Scan in Patients Diagnosed With Head & Neck Cancer October 29, 2020 May 30, 2022
NCT03896958 Unknown status The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) March 21, 2019 March 12, 2024
NCT02013453 Withdrawn Phase 2 A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer December 2013
NCT05331131 Withdrawn Phase 2 Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial September 19, 2022 November 14, 2025