Annotation Detail
Information
- Associated Genes
- IFNG
- Associated Variants
-
IFNG MUTATION
IFNG MUTATION - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- After 24weeks of treatment, percentages of IFNγ-induced pSTAT1+ and IL-10-induced pSTAT3+ monocytes in RA patients increased, reaching levels comparable to HDs. pSTAT1+ and pSTAT3+ cells correlated inversely with RA disease activity index and levels of pSTAT+ cells at baseline were higher in patients with good EULAR response to tocilizumab.
- Pubmed
- 25847223
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.146664773768916
Drugs