spinal muscular atrophy
Information
- Disease name
- spinal muscular atrophy
- Disease ID
- DOID:12377
- Description
- "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy." [url:http\://en.wikipedia.org/wiki/Spinal_muscular_atrophy, url:https\://ghr.nlm.nih.gov/condition/spinal-muscular-atrophy, url:https\://www.genome.gov/Genetic-Disorders/Spinal-Muscular-Atrophy, url:https\://www.ncbi.nlm.nih.gov/pubmed/26022173]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03032172 | Active, not recruiting | Phase 2 | A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy | March 3, 2017 | December 27, 2024 |
| NCT05035823 | Active, not recruiting | N/A | COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis | April 27, 2022 | August 2024 |
| NCT05626855 | Active, not recruiting | Phase 3 | Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab-ONYX | April 17, 2023 | January 1, 2027 |
| NCT05475691 | Active, not recruiting | Longitudinal Data Collection in Pediatric and Adult Patients With Spinal Muscular Atrophy in Latin America | August 17, 2022 | January 30, 2025 | |
| NCT02386553 | Active, not recruiting | Phase 2 | A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy | May 18, 2015 | December 31, 2024 |
| NCT05632666 | Active, not recruiting | N/A | Respiratory Muscle Training in Patients With Spinal Muscular Atrophy (SMA). | February 2, 2021 | January 31, 2023 |
| NCT04888702 | Active, not recruiting | N/A | Holter of Movement in Patients With SMA Undergoing Treatment. | August 8, 2018 | July 30, 2024 |
| NCT04159987 | Active, not recruiting | N/A | Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA® | February 25, 2020 | August 25, 2025 |
| NCT04139343 | Active, not recruiting | Motor Unit Number Estimation (MUNE) in Adults With Spinal Muscular Atrophy (SMA) | August 10, 2018 | December 31, 2024 | |
| NCT05522361 | Active, not recruiting | Phase 4 | Risdiplam in Patients With Spinal Muscular Atrophy Previously Treated With Nusinersen | November 6, 2022 | June 15, 2026 |
| NCT05337553 | Active, not recruiting | Phase 3 | A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy | July 6, 2022 | January 2025 |
| NCT05156320 | Active, not recruiting | Phase 3 | Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam | February 24, 2022 | December 2024 |
| NCT05117827 | Active, not recruiting | N/A | Pediatric Powered Wheelchair Standing Devices: An Exploratory Study | November 12, 2021 | October 31, 2024 |
| NCT05386680 | Active, not recruiting | Phase 3 | Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam | January 12, 2023 | December 3, 2024 |
| NCT03955679 | Approved for marketing | AveXis Managed Access Program Cohort for Access to AVXS-101 | |||
| NCT01522079 | Completed | N/A | Spinal Muscular Atrophy and Cardiac Autonomic Function | January 2011 | October 2011 |
| NCT01611610 | Completed | N/A | Clinical Assessment of Spinal Muscular Atrophy Type II and III (SMA Europe) | May 2011 | May 2013 |
| NCT01645787 | Completed | Phase 2/Phase 3 | Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients | June 2012 | September 2015 |
| NCT01703988 | Completed | Phase 1/Phase 2 | An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy | October 31, 2012 | January 31, 2015 |
| NCT01754441 | Completed | Mechanisms of Cell Death in Spinal Muscular Atrophy | May 2008 | February 2020 | |
| NCT01780246 | Completed | Phase 1 | An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701) | January 31, 2013 | February 28, 2014 |
| NCT01839656 | Completed | Phase 2 | A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA) | May 8, 2013 | August 21, 2017 |
| NCT01931644 | Completed | At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions | July 2013 | April 2024 | |
| NCT01981915 | Completed | N/A | Optimum Insufflation Capacity in NMD | January 2011 | March 2013 |
| NCT02003937 | Completed | N/A | Aerobic Training in Patients With Spinal Muscular Atrophy Type III | September 2009 | September 2010 |
| NCT02052791 | Completed | Phase 1 | An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246) | January 31, 2014 | January 31, 2017 |
| NCT02123186 | Completed | Newborn Screening for Spinal Muscular Atrophy | October 2013 | October 2016 | |
| NCT00004771 | Completed | Phase 2 | Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease | October 1992 | |
| NCT02268552 | Completed | Phase 1/Phase 2 | An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA) | April 2, 2015 | December 29, 2022 |
| NCT02292537 | Completed | Phase 3 | A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA) | November 24, 2014 | February 20, 2017 |
| NCT02428673 | Completed | N/A | Effects of Standing on Non-Ambulatory Children With Neuromuscular Conditions | December 9, 2015 | March 23, 2018 |
| NCT02594124 | Completed | Phase 3 | A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies | November 4, 2015 | August 21, 2023 |
| NCT02633709 | Completed | Phase 1 | A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) Given by Mouth in Healthy Volunteers | January 7, 2016 | August 4, 2016 |
| NCT02644668 | Completed | Phase 2 | A Study of CK-2127107 in Patients With Spinal Muscular Atrophy | January 14, 2016 | May 31, 2018 |
| NCT02941328 | Completed | Phase 2 | SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4 | December 2015 | January 2018 |
| NCT02218593 | Completed | WREX Outcome Study | July 2014 | July 2015 | |
| NCT00061607 | Completed | Measuring Levels of SMN in Blood Samples of SMA Patients | May 19, 2003 | April 4, 2017 | |
| NCT00227266 | Completed | Phase 2 | Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy | September 2005 | November 2007 |
| NCT00374075 | Completed | Phase 1 | Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular Atrophy | September 2003 | February 2006 |
| NCT00443066 | Completed | Clinical Study of Spinal Muscular Atrophy | May 2005 | August 17, 2011 | |
| NCT00481013 | Completed | Phase 2 | Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy | July 2007 | November 2010 |
| NCT00485511 | Completed | Phase 2/Phase 3 | A Trial of Hydroxyurea in Spinal Muscular Atrophy | June 2007 | June 2009 |
| NCT00528268 | Completed | Phase 1/Phase 2 | Study to Evaluate Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular Atrophy | July 2007 | December 2013 |
| NCT00756821 | Completed | A Pilot Study of Biomarkers for Spinal Muscular Atrophy | October 2008 | March 2009 | |
| NCT01028833 | Completed | Phase 2 | Effects of Power Mobility on Young Children With Severe Motor Impairments | November 2008 | December 2012 |
| NCT01033331 | Completed | Evaluation of the Muscle Strength and Motor Ability in Children With Spinal Muscle Atrophy(SMA) Treated With Valproic Acid | July 2006 | December 2008 | |
| NCT01059240 | Completed | SMN Copy Number Distribution in Mali, West Africa | January 21, 2010 | May 18, 2017 | |
| NCT01166022 | Completed | N/A | Clinical Trial of Exercise in Patients With Spinal Muscular Atrophy (SMA) | December 2010 | August 2014 |
| NCT01422200 | Completed | Phase 4 | Flu Vaccine Study in Neuromuscular Patients 2011 | August 2011 | May 2012 |
| NCT01494701 | Completed | Phase 1 | An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) | November 30, 2011 | January 31, 2013 |
| NCT03223051 | Completed | N/A | Development of a Space Exploration Assessment for Children With Spinal Muscular Atrophy | September 7, 2017 | November 22, 2019 |
| NCT03339830 | Completed | European Registry of Patients With Infantile-onset Spinal Muscular Atrophy | October 10, 2017 | November 15, 2020 | |
| NCT03505099 | Completed | Phase 3 | Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2 | April 2, 2018 | June 15, 2021 |
| NCT03554343 | Completed | Sun May Arise on SMA : Newborn Screening of Spinal Muscular Atrophy in Belgium | March 5, 2018 | February 28, 2021 | |
| NCT03808233 | Completed | Reliability and Validity of the ACTIVE-mini for Quantifying Movement in Infants With Spinal Muscular Atrophy | November 5, 2016 | August 31, 2018 | |
| NCT03921528 | Completed | Phase 2 | An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy | April 22, 2019 | February 28, 2024 |
| NCT03970135 | Completed | N/A | Fat and Glucose Metabolism in Fed and Fasted State in Patients With Low Skeletal Muscle Mass | May 29, 2017 | November 30, 2017 |
| NCT03988907 | Completed | Phase 1 | A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy Participants | June 18, 2019 | September 29, 2019 |
| NCT04115475 | Completed | N/A | New Imaging Biomarkers for Muscular Diseases - Multispectral Optoacoustic Imaging in Spinal Muscular Atrophy | November 7, 2019 | January 30, 2020 |
| NCT04228718 | Completed | The Burden of Primary Caregivers of Spinal Muscular Atrophy Patients and Their Needs | July 1, 2019 | May 1, 2020 | |
| NCT04335942 | Completed | N/A | Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor | September 30, 2021 | June 1, 2023 |
| NCT04404764 | Completed | Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational Study | May 27, 2020 | April 23, 2021 | |
| NCT04587492 | Completed | Metabolomics of Children With SMA | January 1, 2017 | September 30, 2020 | |
| NCT04591678 | Completed | Adults With SMA Treated With Nusinersen | October 1, 2018 | June 25, 2021 | |
| NCT04602195 | Completed | Responsiveness and Validation Study of MFM-32 in SMA Patients Treated With Nusinersen | January 19, 2021 | November 10, 2023 | |
| NCT04851873 | Completed | Phase 3 | Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) | September 8, 2021 | June 13, 2023 |
| NCT05109637 | Completed | N/A | A Study to Assess the Clinical Validity of Konectom™ in Adults Living With Neuromuscular Disorders | February 10, 2022 | July 25, 2023 |
| NCT05237544 | Completed | Newborn Screening for Spinal Muscular Atrophy (SMA) - a Proof of Principle Study Using Anonymised Blood Spots. | November 11, 2019 | March 30, 2021 | |
| NCT05644899 | Completed | Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study) | December 16, 2022 | January 10, 2023 | |
| NCT06027385 | Completed | N/A | Genetic Newborn Screening for Cystinosis and Spinal Muscular Atrophy | January 15, 2018 | September 30, 2022 |
| NCT06178393 | Completed | Real-World Use of Novel Treatments in Patients With Spinal Muscular Atrophy (SMA): A Multi-Site Retrospective Chart Review of Pediatric SMA Patients Outside of the United States | May 5, 2022 | December 30, 2022 | |
| NCT05539456 | Enrolling by invitation | Reliability and Validity of the Turkish Version of the PedsQL 3.0 Neuromuscular Module for 2-to 4- Year-old | September 1, 2022 | November 1, 2022 | |
| NCT05521217 | Enrolling by invitation | Myotonometer Intra- and Inter Examiner Reliability on Spinal Muscular Atrophy | August 26, 2022 | October 15, 2022 | |
| NCT03655223 | Enrolling by invitation | Early Check: Expanded Screening in Newborns | October 15, 2018 | December 31, 2025 | |
| NCT06396325 | Not yet recruiting | N/A | A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy | June 1, 2024 | December 31, 2027 |
| NCT06288230 | Not yet recruiting | Phase 1/Phase 2 | An Open Label Study of Gene Therapy Product in Spinal Muscular Atrophy Patients | March 1, 2024 | March 1, 2027 |
| NCT06300996 | Not yet recruiting | N/A | Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb | September 2024 | September 2029 |
| NCT06321965 | Not yet recruiting | N/A | Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy | April 1, 2024 | October 1, 2027 |
| NCT05931211 | Not yet recruiting | Motor Function and Activity of Daily Life in Spinal Muscular Atrophy | June 30, 2023 | December 31, 2024 | |
| NCT05866939 | Not yet recruiting | Development of a Multidisciplinary Network for Clinical and Laboratory Research for SMA | June 30, 2023 | June 30, 2025 | |
| NCT04833348 | Recruiting | N/A | Quantification of Motor Function in Infants With Spinal Muscular Atrophy Treated With Innovative Therapies | March 20, 2021 | March 2027 |
| NCT04177134 | Recruiting | French Register of Patients With Spinal Muscular Atrophy | January 31, 2020 | January 31, 2029 | |
| NCT04292574 | Recruiting | UK SMA Patient Registry | July 13, 2008 | December 31, 2023 | |
| NCT05994950 | Recruiting | A Review of the Management and Outcomes of Children With SMA in the West Midlands During 2017-2022 | December 6, 2023 | December 31, 2024 | |
| NCT04576494 | Recruiting | N/A | Study of the Functional Effects of Nusinersen in 5q-spinal Muscular Amyotrophy Adults (SMA Type 2 or 3 Forms) | January 24, 2022 | June 2025 |
| NCT06167954 | Recruiting | N/A | Safety and Usability of a Robotic Gait Device for Children and Adolescents With Neurological or Neuromuscular Disease in Their Natural Environment | December 4, 2023 | March 8, 2024 |
| NCT06419322 | Recruiting | N/A | Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA). | June 2024 | December 2026 |
| NCT04690998 | Recruiting | N/A | Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients | July 13, 2021 | July 13, 2025 |
| NCT04773470 | Recruiting | N/A | Quantitative Assessment of Dysphagia in Spinal Muscle Atrophy | February 1, 2022 | April 1, 2024 |
| NCT04798378 | Recruiting | N/A | NuroSleeve Powered Brace & Stimulation System to Restore Arm Function | April 16, 2020 | December 2025 |
| NCT05341453 | Recruiting | N/A | Hippotherapy in Children With Spinal Muscular Atrophy | April 22, 2022 | October 22, 2024 |
| NCT05366465 | Recruiting | Quality of Life and Participation of the Adult With Spinal Muscular Atrophy in France | October 19, 2022 | October 19, 2024 | |
| NCT05409079 | Recruiting | N/A | Schulze Muscular Dystrophy Ability Clinical Study | May 26, 2022 | June 30, 2023 |
| NCT05518773 | Recruiting | Mechanisms and Treatment of Exercise Intolerance and Persistent Fatigue in Spinal Muscular Atrophy | December 15, 2022 | September 1, 2025 | |
| NCT05589987 | Recruiting | N/A | Spinal Muscular Atrophy on Wheels, Using Power Mobility | October 1, 2022 | February 1, 2024 |
| NCT05638750 | Recruiting | N/A | Outpatient Rehabilitation Intervention for Young Children With SMA | January 1, 2022 | December 2024 |
| NCT06368076 | Recruiting | N/A | High-intensity Interval Training in Patients With Spinal Muscular Atrophy | January 9, 2024 | January 2025 |
| NCT05663008 | Recruiting | Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis | October 1, 2015 | September 30, 2027 | |
| NCT05712330 | Recruiting | N/A | Exploratory Study of Respiratory Bacterial Infections or Superinfections and Colonizations in Patients With Spinal Muscular Atrophy Under NIV | January 24, 2023 | September 2024 |
| NCT03217578 | Recruiting | Neonatal Spinal Muscular Atrophy (SMA) Screening | September 1, 2017 | December 31, 2030 | |
| NCT05760209 | Recruiting | SMN Circular RNAs as Potential New Targets and Biomarkers for SMA | July 22, 2021 | July 21, 2024 | |
| NCT05761262 | Recruiting | SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients | December 13, 2019 | April 13, 2024 | |
| NCT05768048 | Recruiting | Long Term Trajectories of SMA Patients Receiving or Not Disease-modifying Treatments | November 28, 2022 | November 27, 2027 | |
| NCT03520179 | Recruiting | Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA) | December 17, 2013 | August 12, 2023 | |
| NCT05769465 | Recruiting | MAP THE SMA: a Machine-learning Based Algorithm to Predict THErapeutic Response in Spinal Muscular Atrophy | April 1, 2023 | April 1, 2026 | |
| NCT03709784 | Recruiting | Spinraza in Adult Spinal Muscular Atrophy | August 16, 2018 | January 1, 2025 | |
| NCT05779956 | Recruiting | Personalized Medicine for SMA: a Translational Project | September 1, 2021 | August 31, 2024 | |
| NCT05794139 | Recruiting | Phase 2 | Safety and Efficacy of NMD670 in Ambulatory Adult Patients With Type 3 Spinal Muscular Atrophy | September 21, 2023 | December 2024 |
| NCT05824169 | Recruiting | Phase 1/Phase 2 | Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 1 Patients | February 25, 2023 | December 2025 |
| NCT05866419 | Recruiting | N/A | Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy | November 27, 2023 | March 2027 |
| NCT04010604 | Recruiting | A Registered Cohort Study on SMA | July 1, 2019 | December 31, 2049 | |
| NCT02532244 | Recruiting | Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases | June 2015 | December 2025 | |
| NCT05067790 | Recruiting | Phase 3 | A Study to Evaluate Higher Dose (HD) Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy Previously Treated With Risdiplam | January 21, 2022 | June 14, 2027 |
| NCT06310421 | Recruiting | Spinal Muscular Atrophy Neonatal Screening Program | October 16, 2023 | May 31, 2026 | |
| NCT05219487 | Recruiting | Investigating NMJ Defects in SMA Following Central and Peripheral SMN Restoration | October 13, 2021 | December 31, 2024 | |
| NCT05232929 | Recruiting | Phase 4 | Long-Term Follow-Up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA) | June 14, 2022 | June 1, 2029 |
| NCT02550691 | Terminated | N/A | Identification of a Biomarker Associated With Cis-duplication of the SMN1 Gene | December 15, 2015 | July 4, 2016 |
| NCT02462759 | Terminated | Phase 2 | A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA). | August 19, 2015 | September 24, 2018 |
| NCT03381729 | Terminated | Phase 1 | Study of Intrathecal Administration of Onasemnogene Abeparvovec-xioi for Spinal Muscular Atrophy | December 14, 2017 | November 18, 2021 |
| NCT01547871 | Terminated | Infants With Spinal Muscular Atrophy Type I | February 7, 2012 | April 14, 2016 | |
| NCT02193074 | Terminated | Phase 3 | A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy | August 19, 2014 | November 21, 2016 |
| NCT04262570 | Unknown status | N/A | Evaluation of Therapeutic Response in Spinal Muscular Atrophy Using Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI) | February 25, 2020 | February 2022 |
| NCT02124616 | Unknown status | National Registry for Egyptian Pediatric Neuromuscular Diseases | April 2014 | December 2020 | |
| NCT02831296 | Unknown status | Prospective Evaluation of Infants With Spinal Muscular Atrophy: | February 2016 | ||
| NCT04644393 | Unknown status | Responsiveness and Validation Study of MFM-20 in SMA Patients Treated With Nusinersen | November 2020 | March 2021 | |
| NCT01671384 | Unknown status | Phase 3 | Valproate and Levocarnitine in Children With Spinal Muscular Atrophy | August 2013 | December 2016 |
| NCT03689660 | Unknown status | N/A | Feasibility of Virtual Reality in Children With Neuromuscular Disease, Effectiveness of Virtual Reality and Biofeedback | February 1, 2019 | October 1, 2023 |
| NCT03300869 | Unknown status | Natural History of Types 2 and 3 SMA in Taiwan | September 1, 2017 | December 2019 | |
| NCT00155168 | Unknown status | Quantitative Analysis of SMN1 and SMN2 Gene Based on DHPLC System | April 2004 | ||
| NCT00154960 | Unknown status | Establishing Novel Detection Techniques for Various Genetic-Related Diseases by Applying DHPLC Platform. | June 2004 | ||
| NCT05110885 | Unknown status | Public AttitudesTowards SMA and DMD Awareness, Newborn and Carrier Screening and Physiotherapy Practices | November 2021 | January 2022 | |
| NCT02227407 | Unknown status | N/A | Reciprocating Gait Orthoses for Paraplegia Patients | August 2013 | January 2016 |
| NCT05187260 | Unknown status | Antisense Oligonucleotide for Spinal Muscular Atrophy | January 1, 2022 | January 31, 2024 | |
| NCT00961103 | Unknown status | Motor Development and Orthoses in Spinal Muscular Atrophy (SMA) | September 2009 | December 2009 | |
| NCT04859179 | Unknown status | Prenatal Carrier Screening for Spinal Muscular Atrophy Among Thai Pregnant Women | March 10, 2021 | March 2022 | |
| NCT05041114 | Withdrawn | N/A | SWITCH II Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis | April 21, 2022 | November 30, 2022 |
| NCT02235090 | Withdrawn | N/A | Study of Feasibility to Reliably Measure Functional Abilities' Changes in Nonambulant Neuromuscular Patients Without Trial Site Visiting | October 2016 | October 30, 2017 |
| NCT04050852 | Withdrawn | Early Phase 1 | Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen Treatments | July 17, 2019 | April 1, 2021 |
- Disase is a (Disease Ontology)
- DOID:231
- Cross Reference ID (Disease Ontology)
- GARD:7674
- Cross Reference ID (Disease Ontology)
- ICD10CM:G12.9
- Cross Reference ID (Disease Ontology)
- ICD9CM:335.1
- Cross Reference ID (Disease Ontology)
- MESH:D009134
- Cross Reference ID (Disease Ontology)
- NCI:C85075
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:5262007
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0026847
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0007269