Annotation Detail

Information
Associated Genes
IFNG
Associated Variants
IFNG MUTATION
IFNG MUTATION
Associated Disease
Lung Neoplasms
Source Database
DisGeNET
Description
We found decreased levels of the transcription factor T-box expressed in T cells (T-bet or Tbx21) and of the downstream activated IFN-γ-dependent pSTAT1α isoform in the lung tumour areas of patients with NSCLC as compared with tumour-free control regions.
Pubmed
26348446
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.122995792114547
Drugs