Brain Neoplasms
Information
- Disease name
- Brain Neoplasms
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT01988675 | Completed | MRI Study of Radiation-Induced Damage to White Matter and Blood-Brain-Barrier | August 26, 2004 | June 3, 2014 | |
| NCT00001565 | Completed | Phase 1 | Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy | December 1996 | October 2000 |
| NCT00001807 | Completed | (1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy | April 16, 1999 | April 18, 2019 | |
| NCT00001502 | Completed | Phase 1 | A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors | April 1996 | March 2000 |
| NCT06211803 | Completed | Clinical Application of the Prototype J-PET Device | March 11, 2022 | March 22, 2022 | |
| NCT02105233 | Completed | Phase 1 | Improving Ultrasound Images in Brain Tumor Surgery With the Use of Brain Mimicking Fluid | February 2014 | May 2016 |
| NCT00038441 | Completed | Phase 1/Phase 2 | Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas | September 1995 | August 2005 |
| NCT05946928 | Completed | EMERGENCE AGITATION After Premedication IN PAEDIATRIC MAGNETIC RESONANCE IMAGING: A RETROSPECTIVE COHORT STUDY | March 1, 2022 | December 15, 2022 | |
| NCT00054795 | Completed | Phase 3 | Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART) | ||
| NCT00062478 | Completed | Phase 2 | Study of Karenitecin (BNP1350) in Patients With Brain Tumors | October 2001 | |
| NCT00075166 | Completed | Phase 4 | Surgery Versus Radiosurgery to Treat Metastatic Brain Tumors | December 2003 | November 2005 |
| NCT00076856 | Completed | Phase 2 | Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247) | March 31, 2004 | March 31, 2006 |
| NCT03910556 | Completed | Re-craniotomy and Complications After Elective Neurosurgery | January 2017 | February 2019 | |
| NCT00123760 | Completed | Phase 2/Phase 3 | Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer | February 2004 | December 2008 |
| NCT00128986 | Completed | Phase 1 | Study of Tomotherapy in Patients With Benign Brain Tumour | May 2005 | August 2014 |
| NCT00138788 | Completed | Phase 3 | Brain Metastases Study: Radiotherapy Fractionation Schemes in the Treatment of Brain Metastases | February 1996 | March 2007 |
| NCT03614403 | Completed | N/A | The Effect of Vitamin D3 on Postoperative Pain in Patients Undergoing Craniotomy | July 30, 2017 | November 30, 2018 |
| NCT00207298 | Completed | 18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography in Oncology | June 2005 | August 2015 | |
| NCT00214175 | Completed | Determination of Fraction Size Equivalent Dose (FED) Levels for Intracranial Conformal Avoidance Radiotherapy | June 2004 | January 2011 | |
| NCT00233350 | Completed | Clinical Evaluation of Navigated 3D Ultrasound Multicentre Study | January 2007 | December 2009 | |
| NCT03574467 | Completed | Functional Outcomes of The Bobath Approach on Patients With Brain Tumors: Comparison With Stroke Patients | February 15, 2018 | June 12, 2018 | |
| NCT00280475 | Completed | Phase 3 | A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis | January 2006 | January 2013 |
| NCT00297024 | Completed | Phase 2 | Radiotherapy - Cerebrovascular Reactivity (RT-CVR Study) | February 2005 | May 2013 |
| NCT00312728 | Completed | Phase 2 | A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT) | March 2006 | June 2009 |
| NCT00314808 | Completed | Phase 1 | A Pilot Study of Dronabinol for Adult Patients With Primary Gliomas | April 2006 | April 2012 |
| NCT00392119 | Completed | Phase 1 | MR Guided Laser Interstitial Thermal Therapy for the "Minimal Invasive" Treatment of Brain Metastasis and Primary Brain Tumors | October 2006 | December 2008 |
| NCT00393965 | Completed | Phase 1 | Multiple Dose Study of MPC-6827 in Subjects With Refractory Brain Metastases | December 2005 | February 2008 |
| NCT03525080 | Completed | N/A | Comparison of 6-fluoro-[18F]-L-dihydroxyphenylalanine (18F-DOPA) Positron Emission Tomography (PET) and Multiparametric Resonance Magnetic Imagery (RMI) in Initial Exploration of Glial Tumors | June 12, 2018 | September 11, 2019 |
| NCT00463203 | Completed | Phase 2 | Bevacizumab and Irinotecan for Patients With Primary Brain Tumors and Progression After Standard Therapy | March 2007 | June 2011 |
| NCT03399864 | Completed | N/A | Effectiveness of Musical Training in Hong Kong Chinese Childhood Brain Tumor Survivors | February 20, 2017 | June 30, 2018 |
| NCT03248544 | Completed | N/A | Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery | July 6, 2017 | July 30, 2018 |
| NCT00527657 | Completed | Phase 1 | Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients | February 9, 2006 | February 2, 2012 |
| NCT02884947 | Completed | Improving Surgical Outcomes in Patients With Low Grade Gliomas Using Advanced Pre- and Intra-operative MRI | May 2013 | December 2016 | |
| NCT00649207 | Completed | Phase 1 | A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases | March 2008 | March 2013 |
| NCT02881957 | Completed | Phase 2/Phase 3 | Hypovitaminosis D in Neurocritical Patients | October 10, 2016 | October 10, 2018 |
| NCT00681551 | Completed | Phase 3 | Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis | February 2003 | March 2004 |
| NCT02810899 | Completed | Phase 4 | Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy | September 2015 | June 2016 |
| NCT02791360 | Completed | N/A | Evaluation of Anatomy, Clinical and Neuropsychological Long-term Sequelae of Patients Treated With Radiation Therapy for Brain Tumor | January 2016 | December 2017 |
| NCT02754908 | Completed | N/A | Effectiveness of Musical Training in Children Surviving Brain Tumours | January 2016 | June 30, 2018 |
| NCT00949793 | Completed | Phase 1 | In Vivo Confocal Endomicroscopy of the Brain | March 2008 | November 2009 |
| NCT02707549 | Completed | Phase 2 | Fluid Therapy During Brain Tumor Resection in Children | August 2015 | June 2017 |
| NCT00993057 | Completed | Early Phase 1 | Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | October 2009 | August 2012 |
| NCT02667587 | Completed | Phase 3 | An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) | May 9, 2016 | April 9, 2024 |
| NCT01015534 | Completed | Phase 2 | Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment | January 2006 | October 2009 |
| NCT01017497 | Completed | N/A | Optimal Planning Target Volume With Stereotactic Radiosurgery | December 2009 | December 2013 |
| NCT01128218 | Completed | Phase 1/Phase 2 | A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors | March 2011 | February 2021 |
| NCT02603692 | Completed | Health Related Quality of Life in Pediatric Central Nervous System (CNS) Tumors: A Feasibility Study Utilizing PROMIS | November 2014 | October 2018 | |
| NCT01244737 | Completed | Phase 2 | FLT-PET Imaging of Brain Tumors in Children | October 2010 | February 5, 2023 |
| NCT02389530 | Completed | Use of Fluorescein Dye for the Removal of Brain Tumors | May 2015 | June 2018 | |
| NCT01599052 | Completed | Social Cognition in Children Treated for a Brain Tumour | March 2011 | March 2017 | |
| NCT01642147 | Completed | N/A | Cerebral Blood Perfusion Changes After General Anesthesia for Craniotomy | November 2012 | January 2013 |
| NCT01689402 | Completed | MRI for the Early Evaluation of Acute Intracerebral Hemorrhage | April 2012 | May 2017 | |
| NCT01793714 | Completed | Presurgical Language Mapping With fMRI: Comparison of BOLD and fASL Techniques | January 21, 2014 | December 21, 2017 | |
| NCT01931098 | Completed | Phase 2 | Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab | December 10, 2015 | September 12, 2019 |
| NCT02334722 | Completed | Phase 4 | 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients | August 5, 2015 | October 7, 2020 |
| NCT06001073 | Not yet recruiting | Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics | December 30, 2024 | December 31, 2028 | |
| NCT06322602 | Recruiting | N/A | Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors | February 28, 2024 | March 2029 |
| NCT03861299 | Recruiting | N/A | The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients. | April 1, 2019 | September 1, 2027 |
| NCT04111588 | Recruiting | Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases | November 25, 2019 | October 1, 2024 | |
| NCT04712721 | Recruiting | Early Phase 1 | Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. | October 14, 2021 | June 26, 2024 |
| NCT04755920 | Recruiting | Phase 2 | SGM-101 in Colorectal Brain Metastases. | January 1, 2024 | February 2026 |
| NCT04940507 | Recruiting | N/A | BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial | June 10, 2021 | June 10, 2026 |
| NCT05049148 | Recruiting | N/A | Platelets Activation in Brain Neoplasms | October 20, 2022 | January 20, 2028 |
| NCT05062772 | Recruiting | Brain Tumor Intraoperative Ultrasound Database | May 25, 2022 | December 30, 2023 | |
| NCT05084092 | Recruiting | Phase 2 | IORT After Surgical Resection of Brain Metastases | June 17, 2020 | December 2024 |
| NCT05386108 | Recruiting | Phase 1/Phase 2 | Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/HER2- Breast Cancer | August 31, 2022 | December 2025 |
| NCT05538130 | Recruiting | Phase 1 | A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors | November 30, 2022 | September 28, 2028 |
| NCT05770544 | Recruiting | Phase 2/Phase 3 | DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. | June 2024 | October 2029 |
| NCT05776602 | Recruiting | Fast Brain MRI in Children With Suspected Brain Tumor | May 1, 2023 | December 2025 | |
| NCT05776706 | Recruiting | N/A | Clinical Trial for the Validation of AR Based Neuronavigation System | June 1, 2023 | December 31, 2026 |
| NCT06118723 | Recruiting | The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) | January 1, 2022 | January 1, 2028 | |
| NCT06128148 | Recruiting | Phase 1 | Study of Oral JYP0322 in Patients With Locally Advanced or Metastatic Cancer Targeting ROS1 Molecular Fusion. | May 4, 2022 | December 30, 2024 |
| NCT06165653 | Recruiting | N/A | Guided Meditation During Radiation Therapy for Brain Tumors | February 29, 2024 | January 15, 2028 |
| NCT06273176 | Recruiting | The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma | January 1, 2023 | January 1, 2028 | |
| NCT06322342 | Recruiting | Phase 2 | Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent | March 15, 2024 | March 2025 |
| NCT02773888 | Suspended | N/A | An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring Device | December 2015 | December 2017 |
| NCT02900248 | Terminated | CureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physician Choice | October 2, 2017 | March 29, 2019 | |
| NCT03181581 | Terminated | Phase 2 | Improving Ultrasound Images in Brain Tumour Surgery With the Use of an Acoustic Coupling Fluid Mimicking Brain Tissue. | March 1, 2017 | December 31, 2018 |
| NCT00659334 | Terminated | Phase 2 | Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation | August 2000 | March 2010 |
| NCT00479765 | Terminated | Phase 1/Phase 2 | A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma | March 2007 | October 2009 |
| NCT00234442 | Terminated | Phase 2 | Iressa in the Treatment of Brain Metastases From Non Small Cell Lung Cancer | July 2004 | February 2006 |
| NCT00034697 | Terminated | Phase 2 | Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143) | June 28, 2001 | January 30, 2003 |
| NCT00121420 | Terminated | Phase 2 | Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases | ||
| NCT04543188 | Terminated | Phase 1 | A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement | January 8, 2021 | March 20, 2024 |
| NCT04644315 | Terminated | Phase 2 | A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors | May 24, 2021 | May 16, 2022 |
| NCT00038389 | Terminated | Phase 1 | Study of Vioxx and Radiation Therapy for Brainstem Glioma | October 2001 | January 2005 |
| NCT02279992 | Terminated | Early Phase 1 | Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases | March 27, 2012 | February 11, 2016 |
| NCT01954576 | Terminated | N/A | NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme | October 10, 2013 | May 14, 2021 |
| NCT01582152 | Terminated | Phase 1/Phase 2 | Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma | July 2012 | March 2016 |
| NCT02624388 | Terminated | Phase 2 | Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) | August 2016 | September 2021 |
| NCT02729558 | Terminated | N/A | Local Radiotherapy Following Complete Resection of a Brain Metastasis | May 2015 | May 2017 |
| NCT00769093 | Terminated | Phase 1 | Assessing Dynamic Magnetic Resonance (MR) Imaging in Patients With Recurrent High Grade Glioma Receiving Chemotherapy | October 2008 | July 2014 |
| NCT00004659 | Unknown status | Phase 2 | Phase II Randomized Study of Stereotactic Radiosurgery Plus Fractionated Whole-Brain Radiotherapy Vs Fractionated Whole-Brain Radiotherapy Alone for Multiple Primary or Metastatic Brain Tumors | November 1994 | |
| NCT02007798 | Unknown status | N/A | Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General Anesthesia | January 2014 | December 2014 |
| NCT02149459 | Unknown status | Phase 1 | Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy | June 2014 | July 2018 |
| NCT00204295 | Unknown status | Phase 2 | Study on Amino Acid Uptake in Brain Tumors | January 2004 | |
| NCT03619694 | Unknown status | Role of MR Spectroscopy in Brain Tumors | September 1, 2017 | October 1, 2018 | |
| NCT00787982 | Unknown status | Phase 1/Phase 2 | Magnetic Resonance Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors | September 2008 | September 2010 |
| NCT02655536 | Unknown status | Phase 2 | Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial | August 1, 2017 | December 2019 |
| NCT00040560 | Unknown status | Phase 1 | Study of 111In-DAC as an Medical Imaging Agent for Lung Cancer and Brain Cancer Consistent With Metastatic Lung Cancer | ||
| NCT01012154 | Unknown status | Phase 1 | In Vivo Confocal Microscopy Tumor Atlas Study | November 2009 | December 2010 |
| NCT00484978 | Unknown status | Phase 2 | Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain Metastasis | February 2007 | June 2007 |
| NCT02775136 | Unknown status | N/A | An Evaluation of a Non-invasive Brain Monitor | October 2014 | December 2017 |
| NCT03462914 | Unknown status | Comparative Study Between Different Approaches to CPA-petroclival Meningiomas | March 15, 2018 | May 1, 2019 | |
| NCT00457210 | Unknown status | The Influence of Radiotherapy on Cognitive Function | April 2007 | ||
| NCT00949026 | Withdrawn | Phase 1 | Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral Microdialysis | July 2009 | May 2010 |
| NCT02307604 | Withdrawn | SPECTAbrain: Screening Patients With Brain Tumors for Efficient Clinical Trial Access | May 2016 | January 2019 | |
| NCT00555984 | Withdrawn | N/A | Intravenous Anesthesia Versus Anesthesia With Volatile Agents in Elective Craniotomy for Tumors | September 2007 | March 2010 |
| NCT02795338 | Withdrawn | Multi-modality Localization of Eloquent Brain Function | March 2017 | February 27, 2018 | |
| NCT01236586 | Withdrawn | Phase 1 | RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia | October 8, 2010 | April 13, 2011 |
| NCT00977795 | Withdrawn | Phase 1/Phase 2 | A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors | September 2009 | January 2010 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D001932