allergic conjunctivitis

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Information
Disease name
allergic conjunctivitis
Disease ID
DOID:11204
Description
"A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant." [url:http\://en.wikipedia.org/wiki/Allergic_conjunctivitis] {comment="ls:IEDB"}
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05186025 Active, not recruiting Tyrosine Allergoid Paediatric and Adult Study November 6, 2020 October 2026
NCT04619017 Active, not recruiting Phase 1 Airway Immune Response to Allergens (Use Lay Language Here) October 28, 2021 March 1, 2024
NCT00331500 Completed Phase 3 Olopatadine 0.2% for the Treatment of Allergic Conjunctivitis April 18, 2006 July 27, 2006
NCT00364091 Completed Phase 3 Evaluation of Efficacy of Ophthalmic Solution in Seasonal Allergic Conjunctivitis August 2006
NCT00889330 Completed Phase 3 Safety and Efficacy Study of a Eye Drop for Eye Allergy April 2009
NCT00244543 Completed Phase 3 Evaluation of Efficacy of Ophthalmic Solution in Induced Allergic Conjunctivitis October 2005
NCT03231969 Completed Phase 2 A Single-Center, Phase 2 Study Evaluating Bilastine Ophthalmic Solution in the CAC® Model July 20, 2017 October 11, 2017
NCT03320434 Completed Phase 2 Study Evaluating the Efficacy and Safety of PRT-2761 for the Treatment of Acute and Chronic Allergic Conjunctivitis October 13, 2017 February 18, 2018
NCT03368339 Completed Phase 2 Effectiveness of PR013 Topical Ophthalmic Drops Compared to Vehicle for the Treatment of Allergic Conjunctivitis December 10, 2017 January 28, 2018
NCT03479307 Completed Phase 3 A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model. April 7, 2018 August 10, 2018
NCT03489941 Completed Phase 3 A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and Vehicle April 7, 2018 April 29, 2018
NCT03494504 Completed Phase 3 ALLEVIATE Trial - A Phase 3 Trial in Subjects With Allergic Conjunctivitis March 30, 2018 November 5, 2018
NCT03660878 Completed Phase 1/Phase 2 A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis September 8, 2018 November 19, 2019
NCT03682965 Completed Phase 2 Texan Allergy & Sinus Center Mountain Cedar Intra-Lymphatic Immunotherapy Study September 28, 2018 April 29, 2019
NCT03755557 Completed Phase 3 Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray November 19, 2018 April 5, 2019
NCT03861910 Completed Dietary Choice for the Management of Cow's Milk Allergy Influences Other Allergic Manifestations December 2014 December 2021
NCT04050865 Completed Phase 3 A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis August 5, 2019 February 28, 2020
NCT04207736 Completed Phase 3 The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis. December 5, 2019 February 16, 2021
NCT04389034 Completed Influence of Specific Immunotherapy With Pollinex Quattro (Tree-/Grass Pollen) on Allergen-specific Immunoglobulin E (IgE) Levels April 22, 2020 October 5, 2020
NCT04532710 Completed Phase 2 Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis August 4, 2020 May 27, 2021
NCT04622345 Completed Phase 2 Safety and Efficacy of VSJ-110 in the Treatment of Allergic Conjunctivitis in Adults With a History of Ocular Allergies November 21, 2020 June 28, 2021
NCT04641130 Completed N/A Clinical Validation Study in Allergic Conjunctivitis to Birch Pollen During Allergen Challenge in ALYATEC EEC July 13, 2017 September 11, 2017
NCT04776096 Completed Phase 4 Efficacy and Toxicity of Bepotastine 1,5% PF vs Olopatadine 0,2% With BAK on Allergic Conjunctivitis Treatment March 10, 2021 August 18, 2022
NCT04810390 Completed Phase 3 Study to Assess the Safety, Tolerability and Efficacy of Bilastine Ophthalmic Solution 0.6% in Children March 26, 2021 November 30, 2022
NCT05234554 Completed Phase 3 The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis January 21, 2022 April 22, 2023
NCT05265910 Completed Phase 4 A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Claritin® Tablets 24-Hour in Subjects With Allergic Conjunctivitis December 14, 2021 April 23, 2022
NCT05314621 Completed Phase 4 A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Flonase® Allergy Relief in Subjects With Allergic Conjunctivitis December 31, 2021 July 24, 2022
NCT05579730 Completed Phase 3 Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic Conjunctivitis November 18, 2022 July 22, 2023
NCT05815758 Completed Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic Solution April 20, 2023 September 18, 2023
NCT05824000 Completed N/A PMCF Study to Evaluate Performance and Safety of "Optrex Double Action Soothing and Lubricating Drops" June 7, 2022 August 5, 2022
NCT05829499 Completed N/A PMCF Study to Evaluate Performance and Safety of "Xanoftal Next" December 2, 2022 February 6, 2023
NCT00389025 Completed Phase 4 Mast-Cell Stabilizing Effects of Olopatadine October 2006
NCT00423007 Completed Phase 3 Efficacy and Safety of Topical Bromfenac Ophthalmic Solution vs. Placebo in Subjects With Allergic Conjunctivitis November 2006 August 2007
NCT00432757 Completed Phase 3 Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in Allergic Conjunctivitis January 2007 March 2007
NCT00445874 Completed Phase 3 Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in the Treatment of Allergic Conjunctivitis February 2007 May 2007
NCT00534794 Completed Phase 4 Study of Two Marketed Ocular Anti-Allergy Medications in Subjects With Allergic Conjunctivitis October 2007
NCT00559546 Completed Phase 4 Montelukast as a Controller of Atopic Syndrome March 2007 July 2007
NCT00569777 Completed Phase 3 Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers October 2007 March 2008
NCT00574379 Completed Phase 2 Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR December 2007 March 2008
NCT00586625 Completed Phase 3 Safety Study for Bepotastine Besilate Ophthalmic Solution in Normal Volunteers October 2007
NCT00586664 Completed Phase 3 Efficacy and Safety Study of Bepotastine Besilate Ophthalmic Solution in Allergic Conjunctivitis October 2007 June 2008
NCT00609128 Completed N/A Effect of Olopatadine on Allergic Tear Mediators September 2000 November 2009
NCT00689078 Completed Phase 4 Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model May 2008 June 2008
NCT00769886 Completed Phase 3 Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis. October 2008 June 2009
NCT00770133 Completed Phase 3 Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Acute Allergic Conjunctivitis. February 2010 June 2010
NCT00775658 Completed N/A Olopatadine Eye Drops and Allergy Skin Testing January 2008 June 2008
NCT00818805 Completed Phase 4 Efficacy Investigation Study of Olopatadine Hydrochloride Ophthalmic Solution Using OHIO Chamber in Patients With Seasonal Allergic Rhinitis (SAR) July 2008
NCT00833495 Completed Phase 2 Evaluation of Efficacy of Coadministration of FOV1101-00 and Prednisolone Acetate in Patients With Mild Ongoing Ocular Allergic Inflammation January 2009 March 2009
NCT00836485 Completed Phase 2 Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis February 2009 March 2009
NCT00882687 Completed Phase 2 Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis April 24, 2009 May 10, 2009
NCT00889252 Completed Phase 3 Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers April 2009
NCT00241319 Completed Phase 3 Evaluation of Efficacy of Ophthalmic Solution in Induced Acute Allergic Conjunctivitis October 2005
NCT00982163 Completed A Single-Center Evaluation of the Pattern of Allergic Signs and Symptoms During 4 Weeks in Ragweed Season August 2008 September 2009
NCT00987272 Completed Phase 3 Study of Olopatadine HCl Ophthalmic Solutions Compared to Vehicle Using the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis in Japanese Subjects October 2009 November 2009
NCT01001091 Completed Phase 2 AL-38583 Ophthalmic Solution for Allergic Conjunctivitis Associated Inflammation December 2009 April 2010
NCT01037179 Completed Phase 3 An Open-Label, Long-Term Study With AL-4943A Ophthalmic Solution, 0.2% in Patients With Allergic Conjunctivitis February 2010 May 2010
NCT01107405 Completed Phase 2 Loteprednol Ophthalmic Base Compared to Loteprednol Ophthalmic Suspension vs Placebo in an Allergen Challenge April 2010 August 2010
NCT01109485 Completed Phase 4 Clinical Evaluation of 0.1% Olopatadine Hydrochloride Ophthalmic Solution in Pediatric Patients March 2010 July 2011
NCT01119287 Completed Phase 4 Assessing the Efficacy of Maxidex® and Patanol® for the Treatment of Allergic Conjunctivitis March 2010 September 2010
NCT01120132 Completed Phase 2 Study Evaluating the Efficacy of Administration of Cyclosporine (Low Dose and High Dose) and Prednisolone Acetate Compared to Its Components and Vehicle in Patients With Allergic Conjunctivitis May 2010 August 2010
NCT01134328 Completed Phase 2 Efficacy of AC-150 for the Treatment of Allergic Conjunctivitis in the Enviro-CAC™ Model May 2010 July 2010
NCT01159015 Completed Phase 3 Study Evaluating the Safety of KetoNaph Ophthalmic Solution in Healthy Volunteers July 2010 October 2010
NCT01159769 Completed Phase 4 Patient Perceptions and Quality of Life Associated With the Use of Olapatadine 0.2% for the Treatment of Allergic Conjunctivitis June 2010 August 2010
NCT01174823 Completed Phase 2 Safety and Efficacy of Bepotastine Besilate Ophthalmic Solution in Seasonal Allergic Conjunctivitis Patients June 2010 December 2010
NCT01203540 Completed Phase 4 Evaluation of the Effect and Tolerance of Preservative Free NAAGA on the Inflammatory Component and Symptoms of Dry Eye Syndrome in Allergic Conjunctivitis Patients October 2010 January 2011
NCT01272089 Completed Phase 4 A Study of Patient Perception and Quality of Life Associated With the Use of Olopatadine 0.2% in Subjects With Allergic Conjunctivitis May 2011 December 2011
NCT01275105 Completed Phase 2 A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC) January 2011 March 2011
NCT01282138 Completed Phase 4 Assessment of Alcon's Ocular Image Quantification System December 2010 March 2011
NCT01294969 Completed Phase 4 Patient Perception Study for AL-4943A September 2010 October 2011
NCT01320553 Completed Phase 2 Effect of Different Concentrations of SPARC1102 on Allergic Conjunctivitis June 2011 September 2011
NCT01326858 Completed Phase 1 Safety and Comfort of AL-4943A Ophthalmic Solution April 2011 June 2011
NCT01332188 Completed Phase 2/Phase 3 Efficacy of AC-170 for the Treatment of Allergic Conjunctivitis in the Conjunctival Allergen Challenge (CAC) Model April 2011 October 2011
NCT01339507 Completed A Patient Reported Ocular Comfort Assessment Comparing Bepreve to Lastacaft April 2011 June 2011
NCT01346371 Completed Phase 4 The Effect of BEPREVE 1.5% on Tear Film Osmolarity and Tear Film Lipid Layer May 2011 September 2012
NCT01363700 Completed Phase 3 Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis
NCT01363713 Completed Phase 3 A Long-term Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis
NCT01439815 Completed Phase 4 An Allergen BioCube (ABC) Study Evaluating the Efficacy of Fluticasone Propionate Nasal Spray Compared to Placebo September 2011 October 2011
NCT01443442 Completed Phase 4 Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis October 2011 December 2012
NCT01471184 Completed Phase 1 The Effects of Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops Compared to Placebo September 2009
NCT01479374 Completed Phase 3 Efficacy and Safety of AL-4943A Ophthalmic Solution in Patients With Allergic Conjunctivitis Using the Conjunctival Allergen Challenge (CAC) Model January 2012 March 2012
NCT01534195 Completed Phase 4 Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model January 2012 February 2012
NCT01551056 Completed Phase 3 A Multi-Center Study Evaluating the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle in the Conjunctival Allergen Challenge (CAC) March 2012 June 2012
NCT01561521 Completed Phase 3 An Evaluation of the Onset and Duration of Action of AKF-1 Ophthalmic Solution in Treating Acute Allergic Conjunctivitis March 2012 April 2012
NCT01639846 Completed Phase 2 Evaluation of the Onset and Duration of Action of RX-10045 in Allergic Conjunctivitis July 2012 August 2012
NCT01679015 Completed Evaluating Patients With Eye Allergies and Determining if There Are Also Dry Eyes August 2012 February 2014
NCT01685242 Completed Phase 3 A Single-Center,Evaluation of the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle September 2012 November 2012
NCT01686048 Completed The Significance of Ambrosia in Allergic Rhinitis and Asthma in Israel April 2015 April 2015
NCT01697969 Completed Phase 4 Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients September 2012 July 2013
NCT01698814 Completed Phase 3 A Six-Week Safety Study of an Investigational Ophthalmic Solution October 2012 January 2013
NCT01731249 Completed Phase 3 Efficacy and Safety Study of a Sublingual Immunotherapy Solution to Treat Patients Suffering From Birch Pollen Allergic Rhinoconjunctivitis November 2010 October 2012
NCT01743027 Completed Phase 3 Efficacy and Safety of an Ophthalmic Solution in Patients With Allergic Conjunctivitis January 2013 July 2013
NCT01754766 Completed Phase 2 AGN-229666 for the Treatment of Allergic Conjunctivitis October 2012 February 2013
NCT01881113 Completed Phase 3 A Multi-Center, Evaluation of the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle June 2013 October 2013
NCT02079649 Completed Phase 2 Safety and Efficacy Study of AL-53817 and AL-78843 Ophthalmic Solutions for Allergic Conjunctivitis April 2014 July 2014
NCT02082899 Completed Phase 2 A Single Center Study for the Treatment of Moderate to Severe Allergic Conjunctivitis (EBI-005-AC-1) February 2014 July 2014
NCT02148744 Completed Phase 1 Safety and Tolerability of XmAb®7195 in Adult Healthy Volunteers and Adult Subjects With a History of Allergic Rhinitis and/or Allergic Conjunctivitis and/or Atopic Dermatitis May 2014 September 21, 2015
NCT02251613 Completed Phase 4 Effectiveness of Olopatadine HCl Ophthalmic Solution for the Treatment of Allergic Conjunctivitis in Japan December 2013 January 2014
NCT02308501 Completed Phase 4 A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal Microscopy December 2014 February 2015
NCT02322216 Completed Phase 3 Olopatadine Hydrochloride Ophthalmic Solution Study in Chinese Subjects December 2014 October 2015
NCT02578914 Completed Phase 2 A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis August 2015 December 2015
NCT02978183 Completed Phase 2 Evaluation of the Effectiveness of ST266 Ophthalmic Drops Compared to Placebo to Treat Allergic Conjunctivitis December 2016 November 2017
NCT03101618 Completed Animal Allergy in Korean Pet Owners, Pet-related Industry Workers, and Laboratory Animal Reseachers August 24, 2016 November 27, 2016
NCT06459219 Not yet recruiting Factors Determining Tolerance to Nasal Allergen Exposure With Advanced Age in a Subset of Birch Pollen Allergic Subjects October 1, 2024 October 1, 2028
NCT04198740 Recruiting Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface February 1, 2020 January 2035
NCT05839938 Recruiting N/A The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis August 8, 2022 July 31, 2025
NCT05969236 Recruiting Phase 1 A Study of MDI-1228_mesylate Ophthalmic Solution in Healthy Adults October 6, 2023 October 2024
NCT06293820 Recruiting Phase 2 A Study Of TL-925 For The Treatment of AC March 2024 May 2024
NCT06153342 Recruiting Phase 2 A Study of TL-925 for the Treatment of Allergic Conjunctivitis November 2023 January 2024
NCT03627689 Terminated N/A Molekule for Allergic Rhinitis/Asthma July 13, 2018 January 31, 2019
NCT00276445 Terminated Phase 4 Alleviation of Cedar Pollen Induced Allergic Symptoms by Orally Taken Superfine Beta-1,3-Glucan January 2004 June 2004
NCT01860664 Terminated Phase 2 Hydrocortisone Ophthalmic Ointment 0.5% for Treatment of Allergic Conjunctivitis May 2013 January 1, 2017
NCT03038971 Terminated Phase 1 Study Evaluating Safety of Ragweed Mix Given by Intralymphatic Node Injections March 30, 2017 April 29, 2017
NCT04695795 Unknown status Sea Water in Allergic Conjunctivitis February 1, 2021 December 1, 2022
NCT01337557 Unknown status Phase 4 Use of BEPREVE (Bepotastine Besilate Ophthalmic Solution) 1.5% for Allergic Conjunctivitis and Contact Lenses May 2011 November 2011
NCT00443105 Unknown status Phase 2 Topical Tacrolimus 0.03% Ointment for Intractable Allergic Conjunctivitis: An Open Label Pilot Study
NCT01012752 Unknown status Phase 3 A Multicenter Study to Evaluate Safety and Efficacy of Specific Immunotherapy With Modified Allergen Extracts October 2016 October 2017
NCT01808768 Unknown status Phase 4 Ocular Allergy Treatment Practical Impact Trial April 2013 November 2013
NCT01390961 Unknown status Phase 4 Comparison of Tolerability Between Two Allergy Drops August 2011 January 2012
NCT01878929 Unknown status Phase 1/Phase 2 The Effect of Pollen Season on Subcutaneous Allergen Immunotherapy Reactions April 2013 April 2014
NCT00298337 Unknown status Phase 2/Phase 3 Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008 October 1999 December 2007
NCT03812952 Unknown status China Red Eye Study on Allergic Conjunctivitis August 1, 2018 December 31, 2019
NCT03820154 Unknown status N/A Diagnostic Equivalence of the Skin Prick Test Tape vs. Conventional Skin PrickTest March 1, 2019 July 30, 2019
NCT03862053 Withdrawn Phase 4 Manuka Eye Droops for Treatment of Allergy January 1, 2020 October 7, 2020
NCT00881673 Withdrawn Phase 2 To Evaluate the Efficacy of AL-38583 in the Reduction of Tear Eosinophil Count Following Conjunctival Allergen Challenge May 2009 May 2009
NCT00375596 Withdrawn Phase 2 A Study Of The Safety And Effectiveness Of A New Treatment For Allergic Conjunctivitis
NCT01657240 Withdrawn Phase 3 Clinical Efficacy of PRO-118 Compared With Olopatadine Hydrochloride Ophthalmic Solution in Allergic Conjunctivitis November 2014 May 2015
NCT00489398 Withdrawn Phase 4 Comparison of CL Wear Between Two Allergy Drops July 2007 December 2008
Disase is a (Disease Ontology)
DOID:2475
Cross Reference ID (Disease Ontology)
MESH:D003233
Cross Reference ID (Disease Ontology)
NCI:C34506
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:231854006
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0009766
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0007879