Multiple Sclerosis, Secondary Progressive

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Information
Disease name
Multiple Sclerosis, Secondary Progressive
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00888277 Completed Bayer/Cognitive Assessments With Multiple Sclerosis Subjects May 2009 January 2010
NCT01982942 Completed Phase 2 Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis November 2013 December 2017
NCT06436131 Completed N/A The Effects of In-phase Bilateral Exercise in People With Progressive Multiple Sclerosis October 2, 2023 December 22, 2023
NCT05357833 Completed Early Phase 1 Novel Imaging Markers in SPMS June 1, 2022 September 1, 2023
NCT02988401 Completed Phase 1/Phase 2 Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis December 1, 2017 December 17, 2021
NCT03653585 Completed Cortical Lesions in Patients With Multiple Sclerosis September 4, 2018 September 3, 2020
NCT04211740 Completed Phase 2 Phase II Clinical Trial of OCH-NCNP1 December 6, 2019 May 31, 2023
NCT01433497 Completed Phase 3 Efficacy and Safety of Masitinib in the Treatment of Progressive Multiple Sclerosis August 2011 February 2020
NCT02305264 Completed N/A Imaging of Intracerebral Inflammation in MS March 19, 2012 September 10, 2018
NCT05663853 Completed An Observational Biomarker Study in Multiple Sclerosis (MS) Patients March 28, 2023 April 30, 2024
NCT02308137 Completed Phase 2 Domperidone in Secondary Progressive Multiple Sclerosis (SPMS) February 2015 January 3, 2020
NCT00587691 Completed Phase 1/Phase 2 Dose-Escalation Study of T Cell Vaccine in Multiple Sclerosis July 2002 December 2008
NCT02506751 Completed Phase 1 Open-label Study of Liothyronine in MS July 2015 September 18, 2017
NCT05385731 Not yet recruiting N/A MUSCLE - Nordic Walking in MUltiple SCLErosis August 2, 2022 December 30, 2024
NCT06384976 Not yet recruiting Phase 2 A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis April 2024 January 2029
NCT06390930 Not yet recruiting N/A Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS July 2024 July 2027
NCT06413602 Not yet recruiting N/A The Synergistic Effects of AIH and FES in Persons With MS August 2024 August 2027
NCT06138132 Recruiting Phase 1 A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis April 10, 2024 June 2027
NCT04918225 Recruiting Motor Asymmetry in Progressive Multiple Sclerosis Patients November 3, 2021 May 2026
NCT05013463 Recruiting Phase 2 Hydroxychloroquine and Indapamide in SPMS October 1, 2021 September 1, 2024
NCT05122559 Recruiting Phase 2 Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis February 16, 2022 February 2026
NCT05168384 Recruiting Phase 1/Phase 2 Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple Sclerosis March 26, 2022 June 2025
NCT05204459 Recruiting MS-ResearchBiomarkerS November 11, 2021 November 11, 2041
NCT05496881 Recruiting N/A Exercise Effects in Multiple Sclerosis June 15, 2022 April 30, 2025
NCT05961644 Recruiting Phase 2/Phase 3 Cladribine vs Placebo for Non-active Progressive Multiple Sclerosis (CLASP-MS). October 3, 2022 October 30, 2027
NCT06276634 Recruiting N/A Intermittent Hypoxia in Persons With Multiple Sclerosis April 30, 2024 January 2027
NCT00468611 Terminated Phase 3 Efficacy and Safety of MBP8298 in Subjects With Secondary Progressive Multiple Sclerosis June 2007 September 2009
NCT02430532 Terminated Phase 3 BG00012 and Delay of Disability Progression in Secondary Progressive Multiple Sclerosis May 2015 January 2016
NCT04993274 Unknown status Sensitivity of Motor Assessment in MS - a Prospective Cohort Study February 20, 2019 November 2022
NCT04260711 Unknown status N/A Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS). July 1, 2020 January 1, 2024
NCT02273635 Unknown status Phase 1/Phase 2 Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS September 2014 April 2017