chr1:186671791:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr1:186,640,923-186,650,054 |
| hg38 | chr1:186,671,791-186,680,922 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.225 | squamous cell carcinoma | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.121 | Carcinoma, Transitional Cell | NA | BeFree,CTD_human | Detail | |
| 0.037 | Malignant neoplasm of stomach | In the Chinese subgroup, nominally significant associations were shown between (... | BeFree | 21649724 | Detail |
| 0.031 | stomach carcinoma | In the Chinese subgroup, nominally significant associations were shown between (... | BeFree | 21649724 | Detail |
| 0.005 | Helicobacter pylori infection | In the Chinese subgroup, nominally significant associations were shown between (... | BeFree | 21649724 | Detail |
| 0.130 | Cardiovascular Diseases | Association of cyclooxygenase-2 genetic variant with cardiovascular disease. | BeFree,CTD_human,GAD,LHGDN | 24796340 | Detail |
| 0.130 | Cardiovascular Diseases | Homocysteine and pro-inflammatory mediators such as cyclooxygenase-2 (COX-2) hav... | BeFree,CTD_human,GAD,LHGDN | 25888188 | Detail |
| 0.005 | Carotid Artery Diseases | NA | GAD,LHGDN | Detail | |
| <0.001 | cerebral infarction | NA | BeFree | Detail | |
| 0.205 | brain ischemia | NA | CTD_human,GAD,RGD | Detail | |
| <0.001 | Transient ischemic attack | NA | BeFree | Detail | |
| 0.002 | cerebral palsy | NA | GAD | Detail | |
| 0.005 | Malignant tumor of cervix | NA | BeFree | Detail | |
| 0.008 | Uterine Cervical Neoplasm | NA | GAD,LHGDN | Detail | |
| <0.001 | Primary biliary cirrhosis | NA | BeFree | Detail | |
| <0.001 | Cholangitis, Sclerosing | NA | BeFree | Detail | |
| 0.003 | cholelithiasis | NA | BeFree,GAD | Detail | |
| 0.003 | chondroblastoma | NA | LHGDN | Detail | |
| <0.001 | chondrosarcoma | NA | BeFree | Detail | |
| 0.002 | chorioamnionitis | NA | GAD | Detail | |
| <0.001 | Congenital chromosomal disease | NA | BeFree | Detail | |
| 0.120 | Cognition Disorders | NA | CTD_human | Detail | |
| 0.202 | colitis | NA | BeFree,CTD_human,RGD | Detail | |
| 0.086 | ulcerative colitis | Our study for the first time demonstrated differential expression of the PGE2-re... | BeFree,LHGDN,RGD | 25666316 | Detail |
| 0.086 | ulcerative colitis | (i) Endoscopically normal appearing colonic mucosa of patients with UC-IR remain... | BeFree,LHGDN,RGD | 25827810 | Detail |
| 0.241 | Colonic Neoplasms | NA | BeFree,CTD_human,LHGDN,RGD | Detail | |
| 0.002 | Colonic Polyps | NA | GAD | Detail | |
| 0.051 | colorectal carcinoma | Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug... | BeFree | 23543356 | Detail |
| 0.051 | colorectal carcinoma | Meta-analysis of the association between COX-2 polymorphisms and risk of colorec... | BeFree | 24733273 | Detail |
| 0.051 | colorectal carcinoma | No significant liver cancer and colorectal cancer risk of COX-2 -765G/C polymorp... | BeFree | 24969885 | Detail |
| 0.051 | colorectal carcinoma | Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes an... | BeFree | 24998576 | Detail |
| 0.051 | colorectal carcinoma | Thus, both PTGS2 polymorphisms and PTGS2 mRNA levels may provide information reg... | BeFree | 25166592 | Detail |
| 0.051 | colorectal carcinoma | Our data suggest overexpression of COX-2 protein in colorectal carcinoma in cont... | BeFree | 25169526 | Detail |
| 0.051 | colorectal carcinoma | These findings provide further indication that postdiagnosis aspirin therapy imp... | BeFree | 25239119 | Detail |
| 0.051 | colorectal carcinoma | These findings indicate that miR-21 is a component of the COX-2 inflammation pat... | BeFree | 25310697 | Detail |
| 0.051 | colorectal carcinoma | We expect that paeonol may replace selective COX-2 inhibitors due to their toxic... | BeFree | 25322760 | Detail |
| 0.051 | colorectal carcinoma | STIM1 overexpression promotes colorectal cancer progression, cell motility and C... | BeFree | 25381814 | Detail |
| 0.051 | colorectal carcinoma | These results imply that miR-1297 has the potential to provide a new approach to... | BeFree | 25422199 | Detail |
| 0.051 | colorectal carcinoma | Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase ... | BeFree | 25818893 | Detail |
| 0.051 | colorectal carcinoma | Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal c... | BeFree | 25835114 | Detail |
| 0.051 | colorectal carcinoma | Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and N... | BeFree | 26220687 | Detail |
| 0.199 | Colorectal Neoplasms | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.002 | Connective Tissue Diseases | NA | GAD | Detail | |
| 0.005 | Coronary Arteriosclerosis | NA | BeFree,GAD | Detail | |
| 0.008 | Coronary heart disease | NA | BeFree,GAD | Detail | |
| <0.001 | craniosynostosis | NA | BeFree | Detail | |
| 0.086 | Crohn Disease | NA | BeFree,LHGDN,RGD | Detail | |
| 0.003 | cystic fibrosis | NA | BeFree,GAD | Detail | |
| 0.080 | cystitis | NA | BeFree,RGD | Detail | |
| <0.001 | Cytomegalovirus Infections | NA | BeFree | Detail | |
| 0.002 | Deafness | NA | GAD | Detail | |
| 0.003 | Cessation of life | NA | LHGDN | Detail | |
| 0.002 | Sudden death | NA | GAD | Detail | |
| <0.001 | Presenile dementia | NA | BeFree | Detail | |
| <0.001 | Dengue Fever | NA | BeFree | Detail | |
| 0.006 | Mental Depression | NA | BeFree,GAD | Detail | |
| 0.121 | depressive disorder | NA | BeFree,CTD_human | Detail | |
| <0.001 | Dermatitis, Atopic | NA | BeFree | Detail | |
| <0.001 | dermatomyositis | NA | BeFree | Detail | |
| <0.001 | scleroderma | NA | BeFree | Detail | |
| 0.002 | Diabetes | Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impai... | BeFree | 24342014 | Detail |
| 0.122 | diabetes mellitus | Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impai... | BeFree,CTD_human | 24342014 | Detail |
| 0.200 | Diabetes Mellitus, Experimental | NA | CTD_human,RGD | Detail | |
| 0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| 0.093 | Diabetes Mellitus, Non-Insulin-Dependent | Our results support the hypothesis that T2D pathology contributes in vivo to inc... | BeFree,GAD,LHGDN,RGD | 25095741 | Detail |
| 0.084 | Diabetic Nephropathy | NA | BeFree,LHGDN,RGD | Detail | |
| 0.080 | Diabetic Neuropathies | NA | RGD | Detail | |
| 0.003 | diabetic retinopathy | NA | BeFree,LHGDN | Detail | |
| <0.001 | diarrhea | NA | BeFree | Detail | |
| 0.002 | Digestive System Neoplasms | NA | GAD | Detail | |
| <0.001 | Down syndrome | NA | BeFree | Detail | |
| <0.001 | Dry Eye Syndromes | NA | BeFree | Detail | |
| 0.120 | duodenal ulcer | NA | CTD_human | Detail | |
| <0.001 | Shigella Infections | NA | BeFree | Detail | |
| 0.003 | Dysmenorrhea | NA | LHGDN | Detail | |
| 0.003 | Dyspepsia | NA | BeFree,GAD | Detail | |
| <0.001 | eclampsia | NA | BeFree | Detail | |
| <0.001 | Eczema | NA | BeFree | Detail | |
| 0.120 | Edema | NA | CTD_human | Detail | |
| <0.001 | encephalitis | NA | BeFree | Detail | |
| 0.080 | Experimental Autoimmune Encephalomyelitis | NA | RGD | Detail | |
| 0.019 | Endometrial Neoplasms | NA | LHGDN | Detail | |
| <0.001 | endometrial hyperplasia | NA | BeFree | Detail | |
| 0.233 | endometriosis | The amount of indoleamine 2,3-dioxygenase-1 (IDO1) and cyclooxygenase-2 (COX-2) ... | BeFree,CTD_human,GAD,LHGDN,RGD | 24939730 | Detail |
| 0.233 | endometriosis | Genetic variation in COX-2 -1195 and the risk of endometriosis and adenomyosis. | BeFree,CTD_human,GAD,LHGDN,RGD | 26054111 | Detail |
| 0.003 | Eosinophilia | NA | BeFree,GAD | Detail | |
| 0.003 | Ependymoma | NA | LHGDN | Detail | |
| 0.003 | Epilepsy, Temporal Lobe | NA | LHGDN | Detail | |
| 0.224 | Esophageal Neoplasms | NA | BeFree,CTD_human,GAD,LHGDN,RGD | Detail | |
| 0.001 | esophagitis | NA | BeFree | Detail | |
| 0.003 | peptic esophagitis | NA | BeFree,GAD | Detail | |
| <0.001 | Exanthema | NA | BeFree | Detail | |
| 0.003 | Fatigue | NA | LHGDN | Detail | |
| 0.003 | chronic fatigue syndrome | NA | LHGDN | Detail | |
| 0.080 | Fatty Liver | NA | RGD | Detail | |
| 0.002 | Fetal Diseases | NA | GAD | Detail | |
| 0.083 | Fetal Growth Retardation | NA | LHGDN,RGD | Detail | |
| 0.002 | Fetal Membranes, Premature Rupture | NA | GAD | Detail | |
| 0.080 | Fever | NA | RGD | Detail | |
| <0.001 | breast fibrocystic disease | NA | BeFree | Detail | |
| <0.001 | Fibromatosis | NA | BeFree | Detail | |
| 0.203 | Fibrosis | NA | CTD_human,LHGDN,RGD | Detail | |
| <0.001 | Friedreich ataxia | Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and an... | BeFree | 25104852 | Detail |
| 0.085 | gastritis | NA | BeFree,LHGDN,RGD | Detail | |
| 0.004 | Gastritis, Atrophic | NA | BeFree,GAD | Detail | |
| 0.122 | gastroesophageal reflux disease | NA | BeFree,CTD_human | Detail | |
| <0.001 | Gastrointestinal Neoplasms | NA | BeFree | Detail | |
| 0.001 | Gingival Diseases | NA | BeFree | Detail | |
| <0.001 | Angle Closure Glaucoma | NA | BeFree | Detail | |
| 0.120 | Glaucoma, Open-Angle | NA | CTD_human | Detail | |
| 0.090 | glioblastoma | More importantly, Aβ deposition mediated the inflammatory response of glial cell... | BeFree,GAD,LHGDN,RGD | 24621265 | Detail |
| 0.134 | Glioma | NA | BeFree,CTD_human,LHGDN | Detail | |
| <0.001 | Hamartoma | NA | BeFree | Detail | |
| 0.011 | Head and Neck Neoplasms | NA | GAD,LHGDN | Detail | |
| <0.001 | Headache | NA | BeFree | Detail | |
| 0.002 | Hearing Loss, Partial | NA | GAD | Detail | |
| 0.120 | Heart failure | NA | BeFree,CTD_human | Detail | |
| <0.001 | congestive heart failure | NA | BeFree | Detail | |
| 0.004 | hepatitis | NA | BeFree,LHGDN | Detail | |
| 0.001 | hepatitis A | NA | BeFree | Detail | |
| 0.007 | hepatitis B | NA | BeFree,LHGDN | Detail | |
| <0.001 | Hepatitis, Chronic | NA | BeFree | Detail | |
| 0.007 | hepatitis C | NA | BeFree,LHGDN | Detail | |
| <0.001 | Herpes NOS | NA | BeFree | Detail | |
| <0.001 | Herpes Simplex Infections | NA | BeFree | Detail | |
| <0.001 | Von Hippel-Lindau syndrome | NA | BeFree | Detail | |
| 0.082 | HIV Infections | NA | BeFree,RGD | Detail | |
| 0.005 | Hodgkin Disease | NA | BeFree,GAD | Detail | |
| 0.080 | Huntington disease | NA | RGD | Detail | |
| 0.120 | hydronephrosis | NA | CTD_human | Detail | |
| 0.200 | Hyperalgesia | NA | BeFree,CTD_human,RGD | Detail | |
| 0.120 | Hyperemia | NA | CTD_human | Detail | |
| 0.126 | hyperglycemia | NA | BeFree,CTD_human,LHGDN | Detail | |
| 0.080 | Hyperparathyroidism, Secondary | NA | BeFree,RGD | Detail | |
| 0.123 | Hyperplasia | NA | CTD_human,LHGDN | Detail | |
| 0.002 | Hypersensitivity | NA | GAD | Detail | |
| 0.204 | Hypertensive disease | NA | BeFree,CTD_human,GAD,RGD | Detail | |
| 0.080 | Hypertension, Portal | NA | RGD | Detail | |
| 0.083 | pulmonary hypertension | NA | BeFree,LHGDN,RGD | Detail | |
| <0.001 | Hypertension, Renovascular | NA | BeFree | Detail | |
| <0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
| <0.001 | Immune System Diseases | NA | BeFree | Detail | |
| 0.002 | infertility | NA | GAD | Detail | |
| 0.233 | Inflammation | NA | CTD_human,GAD,LHGDN,RGD | Detail | |
| 0.126 | Inflammatory Bowel Diseases | NA | BeFree,CTD_human,GAD | Detail | |
| <0.001 | influenza | NA | BeFree | Detail | |
| 0.001 | Intestinal Neoplasms | NA | BeFree | Detail | |
| 0.080 | intestinal obstruction | NA | RGD | Detail | |
| 0.121 | Intestinal Polyps | NA | BeFree,CTD_human | Detail | |
| 0.005 | ischemia | NA | BeFree,LHGDN | Detail | |
| <0.001 | Creutzfeldt-Jakob disease | NA | BeFree | Detail | |
| <0.001 | arthropathy | NA | BeFree | Detail | |
| <0.001 | keratoacanthoma | NA | BeFree | Detail | |
| <0.001 | keratosis follicularis | NA | BeFree | Detail | |
| <0.001 | actinic keratosis | NA | BeFree | Detail | |
| 0.121 | Kidney Diseases | NA | BeFree,CTD_human | Detail | |
| 0.122 | Kidney Failure, Chronic | NA | CTD_human,GAD | Detail | |
| 0.120 | Kidney Neoplasm | NA | CTD_human | Detail | |
| <0.001 | acute kidney tubular necrosis | NA | BeFree | Detail | |
| 0.080 | Polycystic Kidney Diseases | NA | RGD | Detail | |
| 0.002 | Premature Obstetric Labor | NA | GAD | Detail | |
| 0.003 | Laryngeal neoplasm | NA | LHGDN | Detail | |
| <0.001 | Fibroid Tumor | NA | BeFree | Detail | |
| 0.120 | leiomyosarcoma | NA | BeFree,CTD_human | Detail | |
| 0.002 | leukemia | NA | BeFree | Detail | |
| 0.124 | chronic lymphocytic leukemia | NA | BeFree,CTD_human,LHGDN | Detail | |
| <0.001 | Acute Erythroblastic Leukemia | NA | BeFree | Detail | |
| 0.003 | lymphoid leukemia | NA | LHGDN | Detail | |
| <0.001 | Leukemia, Lymphocytic, Acute, L1 | Through glycolysis and arachidonic acid metabolism, HK3 and PTGS2 might play imp... | BeFree | 25172542 | Detail |
| 0.001 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| <0.001 | myeloid leukemia | NA | BeFree | Detail | |
| <0.001 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
| <0.001 | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
| 0.003 | acute promyelocytic leukemia | NA | LHGDN | Detail | |
| <0.001 | Leukoplakia | NA | BeFree | Detail | |
| 0.123 | Leukoplakia, Oral | NA | BeFree,CTD_human,GAD | Detail | |
| 0.001 | liver cirrhosis | NA | BeFree | Detail | |
| 0.120 | Liver Cirrhosis, Experimental | NA | CTD_human | Detail | |
| <0.001 | Liver diseases | NA | BeFree | Detail | |
| 0.005 | Liver neoplasms | NA | BeFree,GAD | Detail | |
| 0.124 | Lung diseases | NA | BeFree,CTD_human,LHGDN | Detail | |
| 0.007 | Chronic Obstructive Airway Disease | Effect of a single nucleotide polymorphism in miR-146a on COX-2 protein expressi... | BeFree,GAD | 25767384 | Detail |
| 0.247 | Lung Neoplasms | This shows that COX-2 activity is present during lung tumor development in a hig... | BeFree,CTD_human,LHGDN,RGD | 25057941 | Detail |
| <0.001 | Lupus Vulgaris | NA | BeFree | Detail | |
| <0.001 | Lupus Erythematosus, Discoid | NA | BeFree | Detail | |
| 0.121 | Lupus Erythematosus, Systemic | NA | BeFree,CTD_human | Detail | |
| 0.003 | lupus nephritis | NA | BeFree,LHGDN | Detail | |
| 0.003 | Lyme disease | NA | LHGDN | Detail | |
| 0.004 | Lymphatic Metastasis | NA | BeFree,GAD | Detail | |
| 0.013 | lymphoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Lymphoma, Follicular | NA | BeFree | Detail | |
| 0.005 | Lymphoma, Non-Hodgkin | NA | GAD,LHGDN | Detail | |
| <0.001 | malaria | NA | BeFree | Detail | |
| <0.001 | Malaria, Falciparum | NA | BeFree | Detail | |
| 0.037 | Malignant neoplasm of stomach | We confirm loss of ANXA1 and overexpression of COX-2 in clinical gastric cancer,... | BeFree,GAD | 25038797 | Detail |
| 0.037 | Malignant neoplasm of stomach | In this review, we present the latest clinical and experimental evidence showing... | BeFree,GAD | 25278683 | Detail |
| 0.037 | Malignant neoplasm of stomach | This meta-analysis suggested that the -765G>C polymorphism of the COX-2 gene is ... | BeFree,GAD | 25339021 | Detail |
| 0.037 | Malignant neoplasm of stomach | Cox2 CRAds with 5/3 chimeric-fiber modification, therefore, appear to be a promi... | BeFree,GAD | 26408678 | Detail |
| 0.080 | Mammary Neoplasms, Experimental | NA | RGD | Detail | |
| <0.001 | Marijuana Abuse | To comprehensively analyze the effects of cannabidiolic acid (CBDA), a selective... | BeFree | 25242400 | Detail |
| 0.143 | melanoma | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.004 | meningioma | NA | BeFree,LHGDN | Detail | |
| 0.003 | Mesothelioma | NA | BeFree,LHGDN | Detail | |
| 0.008 | Metaplasia | NA | GAD,LHGDN | Detail | |
| <0.001 | Mixed Salivary Gland Tumor | NA | BeFree | Detail | |
| 0.120 | Mouth Diseases | NA | CTD_human | Detail | |
| 0.213 | Mouth Neoplasms | NA | CTD_human,GAD,LHGDN,RGD | Detail | |
| 0.009 | multiple myeloma | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | multiple sclerosis | NA | BeFree,GAD | Detail | |
| <0.001 | myopathy | NA | BeFree | Detail | |
| 0.002 | Musculoskeletal Diseases | NA | GAD | Detail | |
| <0.001 | mycosis fungoides | NA | BeFree | Detail | |
| 0.016 | myocardial infarction | AMI-1 inhibited the expression of COX2 in TGF-β-stimulated cells. | BeFree,GAD,LHGDN | 26026059 | Detail |
| 0.080 | Myocardial Reperfusion Injury | NA | RGD | Detail | |
| 0.003 | myositis | NA | LHGDN | Detail | |
| 0.003 | Nasal Polyps | NA | BeFree | Detail | |
| 0.002 | Nasopharyngeal Neoplasms | NA | GAD | Detail | |
| 0.002 | Ischemic Cerebrovascular Accident | To investigate whether single nucleotide polymorphisms (SNPs) of eicosanoid bios... | BeFree | 21816595 | Detail |
| 0.002 | Ischemic stroke | To investigate whether single nucleotide polymorphisms (SNPs) of eicosanoid bios... | BeFree | 21816595 | Detail |
| 0.269 | Neoplasm Metastasis | Gene expression analysis showed that several genes involved in tumor development... | BeFree,CTD_human,GAD,LHGDN,RGD | 24961511 | Detail |
| 0.269 | Neoplasm Metastasis | The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenua... | BeFree,CTD_human,GAD,LHGDN,RGD | 25004182 | Detail |
| 0.269 | Neoplasm Metastasis | Co-expression of cancer COX-2 and stromal IDO predicts a worse disease-free and ... | BeFree,CTD_human,GAD,LHGDN,RGD | 25060643 | Detail |
| 0.269 | Neoplasm Metastasis | Taken together, the results obtained here demonstrated that i) CBDA had dual inh... | BeFree,CTD_human,GAD,LHGDN,RGD | 25242400 | Detail |
| 0.269 | Neoplasm Metastasis | Hu-antigen R (HuR) is considered to play a central role in tumor formation, grow... | BeFree,CTD_human,GAD,LHGDN,RGD | 25252849 | Detail |
| 0.269 | Neoplasm Metastasis | Our studies also suggested a new approach to inhibit STIM1-mediated metastasis w... | BeFree,CTD_human,GAD,LHGDN,RGD | 25381814 | Detail |
| 0.269 | Neoplasm Metastasis | Univariate analysis showed that COX-2 protein expression was associated with sho... | BeFree,CTD_human,GAD,LHGDN,RGD | 25511800 | Detail |
| 0.269 | Neoplasm Metastasis | Cyclooxygenase-2 (COX-2) and interleukin-8 (IL-8) are two highly expressed infla... | BeFree,CTD_human,GAD,LHGDN,RGD | 25754990 | Detail |
| 0.269 | Neoplasm Metastasis | Elevated expression of cyclooxygenase-2 (COX-2) is observed in many human cancer... | BeFree,CTD_human,GAD,LHGDN,RGD | 26067757 | Detail |
| 0.122 | Neoplasm Recurrence, Local | NA | CTD_human,GAD | Detail | |
| <0.001 | nephroblastoma | NA | BeFree | Detail | |
| <0.001 | nephrocalcinosis | NA | BeFree | Detail | |
| 0.080 | nephrotic syndrome | NA | RGD | Detail | |
| 0.120 | nervous system disorder | NA | CTD_human | Detail | |
| 0.080 | Neuritis, Autoimmune, Experimental | NA | RGD | Detail | |
| 0.003 | neuroblastoma | The secretion of IL-1β from glioblastoma cells in turn stimulates the expression... | BeFree | 24621265 | Detail |
| 0.003 | neuroblastoma | Gain and loss of β-catenin function, PGE2 , the adenylyl cyclase activator forsk... | BeFree | 25266063 | Detail |
| <0.001 | acoustic neuroma | Overall, this work suggests that COX-2 is a key modulator in VS cell proliferati... | BeFree | 25616959 | Detail |
| <0.001 | Melanocytic nevus | NA | BeFree | Detail | |
| <0.001 | Nodule | NA | BeFree | Detail | |
| <0.001 | Nose Diseases | NA | BeFree | Detail | |
| 0.122 | obesity | In conclusion, our results point to COX-2 as a potential therapeutic target agai... | BeFree,CTD_human | 25422106 | Detail |
| 0.122 | obesity | Investigation regarding the efficacy of a COX-2 inhibitor/aromatase inhibitor co... | BeFree,CTD_human | 25476497 | Detail |
| 0.003 | oligodendroglioma | NA | BeFree,LHGDN | Detail | |
| 0.123 | oral submucous fibrosis | NA | BeFree,CTD_human,GAD | Detail | |
| 0.010 | Degenerative polyarthritis | Using rabbit and human synovial fibroblast cell lines, we examined the effects o... | BeFree,GAD | 25496568 | Detail |
| 0.009 | osteosarcoma | NA | BeFree,LHGDN | Detail | |
| 0.010 | ovarian carcinoma | These findings provided a theoretical basis for determining the function of COX-... | BeFree | 25335121 | Detail |
| 0.003 | Ovarian Cysts | NA | LHGDN | Detail | |
| 0.081 | Pain | At the same location of pain assessment and fibroblast sampling, in situ immunoh... | BeFree,RGD | 25679469 | Detail |
| <0.001 | Pain, Postoperative | NA | BeFree | Detail | |
| 0.134 | Pancreatic Neoplasm | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.120 | pancreatitis | NA | BeFree,CTD_human | Detail | |
| 0.123 | papilloma | NA | BeFree,CTD_human,LHGDN | Detail | |
| 0.008 | Parkinson disease | NA | GAD,LHGDN | Detail | |
| 0.006 | Peptic Ulcer | NA | BeFree,GAD | Detail | |
| 0.120 | pericardial effusion | NA | CTD_human | Detail | |
| 0.001 | Periodontal Diseases | NA | BeFree | Detail | |
| 0.004 | periodontitis | However, susceptibility genes, such as CDKN2BAS (Cyclin Dependend KiNase 2B Anti... | BeFree,GAD | 24528298 | Detail |
| 0.003 | Periodontitis, Juvenile | NA | BeFree,GAD | Detail | |
| <0.001 | peritonitis | NA | BeFree | Detail | |
| 0.001 | Peutz-Jeghers syndrome | NA | BeFree | Detail | |
| 0.003 | Pituitary Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.080 | pleurisy | NA | RGD | Detail | |
| <0.001 | pneumoconiosis | The association between single-nucleotide polymorphisms in cyclooxygenase-2 gene... | BeFree | 24899082 | Detail |
| 0.002 | pneumonia | PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 E... | BeFree | 26026059 | Detail |
| 0.134 | Adenomatous Polyposis Coli | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.021 | polyps | Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal c... | BeFree,LHGDN | 25835114 | Detail |
| 0.002 | Postoperative Complications | NA | GAD | Detail | |
| 0.002 | pre-eclampsia | NA | GAD | Detail | |
| 0.137 | Precancerous Conditions | NA | BeFree,CTD_human,GAD | Detail | |
| 0.002 | Pregnancy Complications, Hematologic | NA | GAD | Detail | |
| 0.152 | Prostatic Neoplasms | NA | BeFree,CTD_human,LHGDN | Detail | |
| 0.080 | prostatitis | NA | RGD | Detail | |
| 0.120 | proteinuria | NA | CTD_human | Detail | |
| 0.120 | Precocious Puberty | NA | CTD_human | Detail | |
| <0.001 | pulmonary edema | NA | BeFree | Detail | |
| 0.080 | pulmonary emphysema | NA | RGD | Detail | |
| 0.081 | pulmonary fibrosis | NA | BeFree,RGD | Detail | |
| <0.001 | Purpura, Thrombotic Thrombocytopenic | NA | BeFree | Detail | |
| 0.003 | Rectal Neoplasms | NA | LHGDN | Detail | |
| 0.200 | Reperfusion Injury | NA | CTD_human,RGD | Detail | |
| 0.003 | Respiratory Syncytial Virus Infections | NA | BeFree,GAD | Detail | |
| <0.001 | Retinal Diseases | NA | BeFree | Detail | |
| <0.001 | retinoblastoma | NA | BeFree | Detail | |
| <0.001 | rhabdomyosarcoma | NA | BeFree | Detail | |
| <0.001 | Rheumatism | NA | BeFree | Detail | |
| <0.001 | Rhinitis, Allergic, Perennial | NA | BeFree | Detail | |
| <0.001 | Rotavirus Infections | NA | BeFree | Detail | |
| <0.001 | Salivary Gland Neoplasms | NA | BeFree | Detail | |
| 0.003 | Salmonella infections | NA | LHGDN | Detail | |
| 0.011 | sarcoidosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | Sarcoidosis, Pulmonary | NA | BeFree,GAD | Detail | |
| <0.001 | Kaposi sarcoma | NA | BeFree | Detail | |
| 0.089 | schizophrenia | NA | BeFree,GAD,LHGDN,RGD | Detail | |
| <0.001 | systemic scleroderma | NA | BeFree | Detail | |
| 0.003 | Sclerosis | NA | LHGDN | Detail | |
| 0.200 | Seizures | NA | BeFree,CTD_human,RGD | Detail | |
| <0.001 | Septicemia | NA | BeFree | Detail | |
| 0.122 | Dermatologic disorders | NA | CTD_human,GAD | Detail | |
| 0.126 | Skin Neoplasms | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.200 | status epilepticus | NA | CTD_human,RGD | Detail | |
| <0.001 | Stomach Diseases | NA | BeFree | Detail | |
| 0.188 | Stomach Neoplasms | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.207 | gastric ulcer | NA | BeFree,CTD_human,LHGDN,RGD | Detail | |
| <0.001 | Stricture of artery | NA | BeFree | Detail | |
| 0.130 | Cerebrovascular accident | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Giant Cell Arteritis | NA | BeFree | Detail | |
| <0.001 | thromboangiitis obliterans | NA | BeFree | Detail | |
| <0.001 | Thromboembolism | NA | BeFree | Detail | |
| 0.123 | thrombosis | NA | CTD_human,LHGDN | Detail | |
| 0.003 | thymoma | NA | BeFree,LHGDN | Detail | |
| 0.003 | Thyroid Diseases | NA | LHGDN | Detail | |
| 0.126 | Thyroid Neoplasm | NA | BeFree,CTD_human,LHGDN | Detail | |
| <0.001 | Thyroid Nodule | NA | BeFree | Detail | |
| 0.120 | Tongue Neoplasms | NA | BeFree,CTD_human | Detail | |
| <0.001 | tuberculosis | Taken together, our findings indicated that mycobacterial HtdY might contribute ... | BeFree | 24907510 | Detail |
| <0.001 | tuberous sclerosis | We recently reported that prostaglandin biosynthesis and cyclooxygenase-2 were d... | BeFree | 25347447 | Detail |
| <0.001 | Unipolar Depression | NA | BeFree | Detail | |
| 0.120 | Adverse reaction to drug | NA | CTD_human | Detail | |
| <0.001 | Erythema | NA | BeFree | Detail | |
| <0.001 | ureteral obstruction | NA | BeFree | Detail | |
| <0.001 | urinary tract infection | NA | BeFree | Detail | |
| <0.001 | urticaria | NA | BeFree | Detail | |
| 0.002 | Uterine Diseases | NA | GAD | Detail | |
| 0.001 | Uterine Fibroids | NA | BeFree | Detail | |
| <0.001 | Vascular Diseases | NA | BeFree | Detail | |
| 0.001 | Virus Diseases | NA | BeFree | Detail | |
| 0.005 | vitiligo | NA | BeFree,GAD | Detail | |
| 0.005 | Vulvar Neoplasms | NA | LHGDN | Detail | |
| 0.080 | Wernicke encephalopathy | NA | RGD | Detail | |
| <0.001 | Xerostomia | NA | BeFree | Detail | |
| 0.001 | Fibromatosis, Aggressive | This study aimed to determine the significance of CTNNB1 (β-catenin) mutations i... | BeFree | 24788118 | Detail |
| 0.014 | Helicobacter Infections | NA | GAD | Detail | |
| 0.123 | B-Cell Lymphomas | NA | BeFree,CTD_human,GAD | Detail | |
| 0.002 | T-Cell Lymphoma | NA | GAD | Detail | |
| <0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
| 0.002 | oligohydramnios | NA | GAD | Detail | |
| <0.001 | ovarian hyperstimulation syndrome | NA | BeFree | Detail | |
| <0.001 | Central Nervous System Neoplasms | Compound 5f exhibited moderate cytotoxicity with 58.79% growth inhibition agains... | BeFree | 25134430 | Detail |
| 0.003 | Neoplasms, Second Primary | NA | LHGDN | Detail | |
| <0.001 | Arthritis, Reactive | NA | BeFree | Detail | |
| <0.001 | Synovial Cyst | NA | BeFree | Detail | |
| <0.001 | polymyositis | NA | BeFree | Detail | |
| 0.001 | Chronic gastritis | NA | BeFree | Detail | |
| <0.001 | Adenosis of Breast | NA | BeFree | Detail | |
| <0.001 | Hamman-Rich syndrome | NA | BeFree | Detail | |
| <0.001 | Ileal Pouches | NA | BeFree | Detail | |
| <0.001 | marasmus | NA | BeFree | Detail | |
| <0.001 | benign neoplasm | NA | BeFree | Detail | |
| 0.003 | Pancreatitis, Chronic | NA | BeFree,LHGDN | Detail | |
| 0.004 | Epstein-Barr Virus Infections | NA | BeFree,LHGDN | Detail | |
| 0.080 | Left Ventricular Hypertrophy | NA | RGD | Detail | |
| <0.001 | Gastric adenoma | NA | BeFree | Detail | |
| <0.001 | Small cell carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | Migraine Disorders | NA | BeFree | Detail | |
| <0.001 | Thyroid Gland Follicular Adenoma | NA | BeFree | Detail | |
| <0.001 | Atrophic condition of skin | NA | BeFree | Detail | |
| 0.127 | Premature Birth | NA | CTD_human,GAD | Detail | |
| <0.001 | Oral Cavity Carcinoma | NA | BeFree | Detail | |
| <0.001 | Cutaneous Melanoma | NA | BeFree | Detail | |
| 0.004 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
| 0.005 | esophageal carcinoma | NA | BeFree | Detail | |
| 0.004 | Malignant neoplasm of mouth | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of gallbladder | NA | BeFree | Detail | |
| <0.001 | uterine cancer | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of testis | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of brain | NA | BeFree,GAD | Detail | |
| <0.001 | Secondary malignant neoplasm of lung | NA | BeFree | Detail | |
| 0.001 | Secondary malignant neoplasm of bone | NA | BeFree | Detail | |
| <0.001 | acute myocardial infarction | AMI-1 inhibited the expression of COX2 in TGF-β-stimulated cells. | BeFree | 26026059 | Detail |
| <0.001 | acute myocarditis | NA | BeFree | Detail | |
| <0.001 | Atherosclerosis of aorta | NA | BeFree | Detail | |
| 0.003 | Streptococcal pneumonia | NA | LHGDN | Detail | |
| <0.001 | Intervertebral Disc Degeneration | NA | BeFree | Detail | |
| 0.003 | Prion Diseases | NA | LHGDN | Detail | |
| 0.083 | Liver Failure, Acute | NA | BeFree,LHGDN,RGD | Detail | |
| 0.120 | Aortic Aneurysm, Abdominal | NA | BeFree,CTD_human | Detail | |
| 0.020 | Tumor Progression | Cholangiocarcinogenesis and tumor progression are regulated by a novel interplay... | BeFree | 24699315 | Detail |
| 0.020 | Tumor Progression | Macrophages are one of the predominant tumor-infiltrating immune cells supportin... | BeFree | 25545478 | Detail |
| <0.001 | Acute onset pain | NA | BeFree | Detail | |
| <0.001 | follicular adenoma | NA | BeFree | Detail | |
| <0.001 | Undifferentiated carcinoma | NA | BeFree | Detail | |
| <0.001 | thymic carcinoma | NA | BeFree | Detail | |
| <0.001 | Lichen Planus, Oral | NA | BeFree | Detail | |
| <0.001 | Cytomegalovirus retinitis | NA | BeFree | Detail | |
| 0.003 | Neuroectodermal Tumor, Primitive | NA | LHGDN | Detail | |
| <0.001 | Adenomatous Polyps | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma, Clear Cell | NA | BeFree | Detail | |
| <0.001 | Follicular thyroid carcinoma | NA | BeFree | Detail | |
| 0.003 | Carcinoma, Lobular | NA | BeFree,LHGDN | Detail | |
| 0.003 | Medullary carcinoma | NA | BeFree,LHGDN | Detail | |
| 0.134 | cholangiocarcinoma | In parallel, cyclooxygenase-2 (COX2) overexpression and PGE2 treatment increased... | BeFree,CTD_human,LHGDN | 24699315 | Detail |
| 0.006 | Cystadenocarcinoma, Serous | NA | BeFree,LHGDN | Detail | |
| 0.001 | Cervical Intraepithelial Neoplasia | NA | BeFree | Detail | |
| 0.003 | Squamous Cell Neoplasms | NA | LHGDN | Detail | |
| 0.080 | gliosarcoma | NA | RGD | Detail | |
| 0.004 | Lip and oral cavity carcinoma | NA | BeFree | Detail | |
| <0.001 | Metastatic malignant neoplasm to brain | Our results suggest the COX2-MMP1/CCL7 axis as a novel therapeutic target for br... | BeFree | 25691572 | Detail |
| <0.001 | Adult type dermatomyositis | NA | BeFree | Detail | |
| <0.001 | Juvenile polyp | NA | BeFree | Detail | |
| <0.001 | chronic cystitis | NA | BeFree | Detail | |
| <0.001 | Inflammatory pain | NA | BeFree | Detail | |
| 0.002 | gallbladder carcinoma | NA | BeFree | Detail | |
| 0.014 | pancreatic carcinoma | Immunohistochemistry staining showed COX-2 in pancreatic carcinoma cells, but no... | BeFree | 24912820 | Detail |
| 0.014 | pancreatic carcinoma | COX-2 is overexpressed in pancreatic cancer, ampullary cancer and distal bile du... | BeFree | 24950702 | Detail |
| 0.014 | pancreatic carcinoma | These findings suggest that COX-2-765*C is related to cancer susceptibility and ... | BeFree | 24969885 | Detail |
| 0.014 | pancreatic carcinoma | Studies of the molecular pathology of pancreatic cancer have revealed that activ... | BeFree | 25152585 | Detail |
| 0.014 | pancreatic carcinoma | Significant inhibition of VEGF, angiopoietin 1, angiopoietin 2, platelet derived... | BeFree | 25497868 | Detail |
| <0.001 | Alcohol or Other Drugs use | NA | BeFree | Detail | |
| <0.001 | Hereditary pancreatitis | NA | BeFree | Detail | |
| <0.001 | Medullary carcinoma of thyroid | NA | BeFree | Detail | |
| 0.001 | Papillary thyroid carcinoma | Combined immunohistochemical evaluation of the levels of COX-2, MMP-9 and VEGF i... | BeFree | 24670538 | Detail |
| <0.001 | bone destruction | NA | BeFree | Detail | |
| 0.001 | Fibrosis, Liver | NA | BeFree | Detail | |
| <0.001 | pelvic inflammatory disease | NA | BeFree | Detail | |
| 0.002 | Dyslipidemias | NA | GAD | Detail | |
| <0.001 | Disk, Herniated | NA | BeFree | Detail | |
| 0.050 | Malignant neoplasm of lung | Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug re... | BeFree,GAD | 24909729 | Detail |
| 0.050 | Malignant neoplasm of lung | Moreover, downregulation of COX-2/PGE2 and MIG-7 significantly prolonged the ove... | BeFree,GAD | 25004182 | Detail |
| 0.050 | Malignant neoplasm of lung | A new class of compounds targeting cyclooxygenase 2 (COX-2) together with other ... | BeFree,GAD | 25113252 | Detail |
| 0.050 | Malignant neoplasm of lung | The obtained results highlight the importance of the genes STAT5B and COX-2 in l... | BeFree,GAD | 25137041 | Detail |
| 0.080 | Parkinsonian Disorders | NA | RGD | Detail | |
| 0.080 | Acute Lung Injury | NA | RGD | Detail | |
| <0.001 | Drug usage | NA | BeFree | Detail | |
| 0.003 | Mucosa-Associated Lymphoid Tissue Lymphoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Sepsis | NA | BeFree | Detail | |
| <0.001 | Carcinoma, Lewis Lung | NA | BeFree | Detail | |
| <0.001 | mixed gliomas | NA | BeFree | Detail | |
| <0.001 | Multiple tumors | NA | BeFree | Detail | |
| <0.001 | Carcinoma of ampulla of Vater | NA | BeFree | Detail | |
| <0.001 | Osteoarthritis of the hand | Our aims were to replicate some previously reported associations of single nucle... | BeFree | 24825461 | Detail |
| <0.001 | Turcot syndrome (disorder) | NA | BeFree | Detail | |
| <0.001 | Ichthyosis linearis circumflexa | NA | BeFree | Detail | |
| 0.006 | Chronic Periodontitis | NA | BeFree,GAD | Detail | |
| <0.001 | Erosive esophagitis | NA | BeFree | Detail | |
| <0.001 | Superficial gastritis | NA | BeFree | Detail | |
| <0.001 | Xeroderma pigmentosum, group A | NA | BeFree | Detail | |
| <0.001 | Cytochrome-c Oxidase Deficiency | NA | BeFree | Detail | |
| <0.001 | Endometrioma | NA | BeFree | Detail | |
| <0.001 | Stage II Colon Cancer | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of colon stage IV | NA | BeFree | Detail | |
| <0.001 | Stage III Breast Cancer AJCC v6 | NA | BeFree | Detail | |
| 0.001 | Carcinoma breast stage IV | NA | BeFree | Detail | |
| 0.002 | gastric adenocarcinoma | Cyclooxygenase-2 inhibition as a strategy for treating gastric adenocarcinoma. | BeFree | 24992958 | Detail |
| 0.001 | Metastatic melanoma | NA | BeFree | Detail | |
| 0.003 | Cancer of Head and Neck | NA | BeFree | Detail | |
| 0.002 | Liver and Intrahepatic Biliary Tract Carcinoma | NA | BeFree | Detail | |
| <0.001 | Invasive lobular breast carcinoma | NA | BeFree | Detail | |
| 0.127 | Squamous cell carcinoma of esophagus | The protein levels of STAT3, phosphorylated STAT3, VEGF, NF-κB p65, phosphorylat... | BeFree,CTD_human | 25405520 | Detail |
| 0.127 | Squamous cell carcinoma of esophagus | Overexpression of phospholipase A2 Group IIA in esophageal squamous cell carcino... | BeFree,CTD_human | 25422234 | Detail |
| 0.126 | Adenocarcinoma Of Esophagus | NA | BeFree,CTD_human | Detail | |
| <0.001 | cervical adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Transitional cell carcinoma of bladder | NA | BeFree | Detail | |
| 0.003 | Solid tumour | A new class of compounds targeting cyclooxygenase 2 (COX-2) together with other ... | BeFree | 25113252 | Detail |
| 0.003 | Solid tumour | The cyclooxygenase-2 (COX-2) enzyme and major lipid product, prostaglandin E2 (P... | BeFree | 25433169 | Detail |
| 0.003 | Solid tumour | The enzyme cyclooxygenase 2 is an inducible enzyme expressed at sites of inflamm... | BeFree | 25900875 | Detail |
| <0.001 | stage, prostate cancer | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of oropharynx | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of the hypopharynx | NA | BeFree | Detail | |
| <0.001 | laryngeal squamous cell carcinoma | NA | BeFree | Detail | |
| <0.001 | diffuse astrocytoma | NA | BeFree | Detail | |
| 0.002 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
| <0.001 | Prostatic Intraepithelial Neoplasias | NA | BeFree | Detail | |
| 0.008 | cervix carcinoma | NA | BeFree,GAD | Detail | |
| <0.001 | Dryness of eye | NA | BeFree | Detail | |
| <0.001 | Anastomosis | Furthermore, using selective COX-2 inhibitors to prevent intra-abdominal adhesio... | BeFree | 26109851 | Detail |
| 0.001 | Healing ulcer | NA | BeFree | Detail | |
| 0.003 | Inflammatory disease of mucous membrane | NA | LHGDN | Detail | |
| <0.001 | Senile Plaques | NA | BeFree | Detail | |
| 0.001 | Tumor necrosis | NA | BeFree | Detail | |
| <0.001 | Infarction, Lacunar | NA | BeFree | Detail | |
| 0.005 | Atrophic | NA | GAD,LHGDN | Detail | |
| <0.001 | Hyperplastic Polyp | NA | BeFree | Detail | |
| <0.001 | Adenosis | NA | BeFree | Detail | |
| <0.001 | Hamartomatous polyp | NA | BeFree | Detail | |
| 0.001 | Multiple polyps | NA | BeFree | Detail | |
| <0.001 | Multiple adenomatous polyps | NA | BeFree | Detail | |
| <0.001 | malignant fibrous histiocytoma | NA | BeFree | Detail | |
| <0.001 | anaplastic oligodendroglioma | NA | BeFree | Detail | |
| 0.001 | Adenocarcinoma of colon | In vitro studies in colonic adenocarcinoma cells revealed that treatment with th... | BeFree | 25310697 | Detail |
| <0.001 | Impaired cognition | Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impai... | BeFree | 24342014 | Detail |
| 0.120 | Thyroid associated opthalmopathies | NA | BeFree,CTD_human | Detail | |
| <0.001 | Glaucoma, Primary Open Angle | NA | BeFree | Detail | |
| <0.001 | Corticosteroid-induced glaucoma | NA | BeFree | Detail | |
| <0.001 | Anterior myocardial infarction | AMI-1 inhibited the expression of COX2 in TGF-β-stimulated cells. | BeFree | 26026059 | Detail |
| <0.001 | Chronic liver disease | NA | BeFree | Detail | |
| <0.001 | endometriosis of uterus | Genetic variation in COX-2 -1195 and the risk of endometriosis and adenomyosis. | BeFree | 26054111 | Detail |
| 0.005 | Complications of Diabetes Mellitus | NA | GAD | Detail | |
| <0.001 | juvenile polyposis syndrome | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of liver | NA | BeFree | Detail | |
| <0.001 | malignant mesothelioma | NA | BeFree | Detail | |
| 0.127 | Squamous cell carcinoma of esophagus | Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic act... | BeFree | 19347867 | Detail |
| <0.001 | intestinal cancer | NA | BeFree | Detail | |
| 0.014 | Malignant neoplasm of pancreas | The aim of the present study was to examine expression of COX-2 in cancer cells ... | BeFree | 24912820 | Detail |
| 0.014 | Malignant neoplasm of pancreas | COX-2 is overexpressed in pancreatic cancer, ampullary cancer and distal bile du... | BeFree | 24950702 | Detail |
| 0.014 | Malignant neoplasm of pancreas | These findings suggest that COX-2-765*C is related to cancer susceptibility and ... | BeFree | 24969885 | Detail |
| 0.014 | Malignant neoplasm of pancreas | Studies of the molecular pathology of pancreatic cancer have revealed that activ... | BeFree | 25152585 | Detail |
| 0.014 | Malignant neoplasm of pancreas | Significant inhibition of VEGF, angiopoietin 1, angiopoietin 2, platelet derived... | BeFree | 25497868 | Detail |
| <0.001 | Disseminated Malignant Neoplasm | NA | BeFree | Detail | |
| <0.001 | Polyp of duodenum | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of central nervous system | Compound 5f exhibited moderate cytotoxicity with 58.79% growth inhibition agains... | BeFree | 25134430 | Detail |
| <0.001 | Early gastric cancer | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of tongue | NA | BeFree | Detail | |
| <0.001 | Pulmonary lymphangioleiomyomatosis | We recently reported that prostaglandin biosynthesis and cyclooxygenase-2 were d... | BeFree | 25347447 | Detail |
| 0.008 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
| <0.001 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of vulva | NA | BeFree | Detail | |
| <0.001 | Skin callus | NA | BeFree | Detail | |
| 0.048 | Malignant neoplasm of prostate | We found that FYN increased COX2 activity in prostate cancer cells DU145, indepe... | BeFree,GAD | 24970799 | Detail |
| 0.048 | Malignant neoplasm of prostate | Analysis of inflammatory genes in the patient tissues revealed that IL-6 express... | BeFree,GAD | 25305352 | Detail |
| 0.048 | Malignant neoplasm of prostate | Vasoactive intestinal peptide (VIP) exerts similar effects in prostate cancer mo... | BeFree,GAD | 25446255 | Detail |
| <0.001 | Hematologic Neoplasms | NA | BeFree | Detail | |
| 0.080 | Endotoxemia | NA | RGD | Detail | |
| <0.001 | Pouchitis | NA | BeFree | Detail | |
| <0.001 | Osteoarthritis of distal interphalangeal joint | Our aims were to replicate some previously reported associations of single nucle... | BeFree | 24825461 | Detail |
| 0.003 | Osteoarthritis, Knee | NA | BeFree,GAD | Detail | |
| 0.003 | lupus erythematosus | NA | BeFree,GAD | Detail | |
| <0.001 | Aortic valve calcification | COX2 inhibition reduces aortic valve calcification in vivo. | BeFree | 25722432 | Detail |
| <0.001 | neuropathy | NA | BeFree | Detail | |
| <0.001 | Non-obstructive reflux-associated chronic pyelonephritis (disorder) | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of liver | NA | BeFree | Detail | |
| <0.001 | dementia | NA | BeFree | Detail | |
| <0.001 | Overweight | NA | BeFree | Detail | |
| 0.002 | Hematocrit level | NA | GAD | Detail | |
| 0.002 | Recurrent tumor | NA | BeFree | Detail | |
| 0.083 | Metabolic syndrome X | NA | BeFree,GAD,RGD | Detail | |
| <0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
| <0.001 | Hepatitis B, Chronic | NA | BeFree | Detail | |
| <0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
| 0.016 | Malignant neoplasm of esophagus | NA | BeFree,GAD | Detail | |
| <0.001 | Abdominal adhesions | Inhibition of cyclooxygenase-2 prevents intra-abdominal adhesions by decreasing ... | BeFree | 26109851 | Detail |
| 0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of skin | NA | BeFree | Detail | |
| 0.001 | Malignant glioma | NA | BeFree | Detail | |
| <0.001 | primary sclerosing cholangitis | NA | BeFree | Detail | |
| <0.001 | Chronic anemia | NA | BeFree | Detail | |
| 0.003 | Osteosarcoma of bone | NA | BeFree | Detail | |
| <0.001 | Intraocular pressure disorder | NA | BeFree | Detail | |
| <0.001 | Aqueous Humor Disorders | NA | BeFree | Detail | |
| 0.001 | Carcinoma of larynx | Experimental data showed upregulation of the selected EGFR cascade in tumor cell... | BeFree | 25736926 | Detail |
| 0.080 | Carcinogenesis | Prostaglandins produced by Cyclooxygenase-2 enzyme have been implicated to have ... | BeFree | 24789723 | Detail |
| 0.080 | Carcinogenesis | Overexpression of cyclooxygenase-2 (COX-2) has been implicated in oncogenesis an... | BeFree | 24950702 | Detail |
| 0.080 | Carcinogenesis | It has been reported that COX-2 expression is associated with MMP-2 expression i... | BeFree | 24998576 | Detail |
| 0.080 | Carcinogenesis | Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis ... | BeFree | 25057941 | Detail |
| 0.080 | Carcinogenesis | Our data suggest overexpression of COX-2 protein in colorectal carcinoma in cont... | BeFree | 25169526 | Detail |
| 0.080 | Carcinogenesis | Helicobacter pylori infection, gastrin and cyclooxygenase-2 in gastric carcinoge... | BeFree | 25278683 | Detail |
| 0.080 | Carcinogenesis | The aim of the present study was to investigate the effects of plasmid-mediated ... | BeFree | 25335121 | Detail |
| 0.080 | Carcinogenesis | The present study aimed to investigate the role of the JAK/STAT3 pathway in the ... | BeFree | 25405520 | Detail |
| 0.080 | Carcinogenesis | Furthermore, miR-1297 could inhibit human colorectal cancer LOVO and HCT116 cell... | BeFree | 25422199 | Detail |
| <0.001 | Chemical Carcinogenesis | NA | BeFree | Detail | |
| <0.001 | monocytic leukemia | The present study aimed to investigate the mechanism by which O. japonicus extra... | BeFree | 25760396 | Detail |
| <0.001 | Tumor Initiation | NA | BeFree | Detail | |
| 0.019 | prostate carcinoma | We found that FYN increased COX2 activity in prostate cancer cells DU145, indepe... | BeFree | 24970799 | Detail |
| 0.019 | prostate carcinoma | Analysis of inflammatory genes in the patient tissues revealed that IL-6 express... | BeFree | 25305352 | Detail |
| 0.019 | prostate carcinoma | Vasoactive intestinal peptide (VIP) exerts similar effects in prostate cancer mo... | BeFree | 25446255 | Detail |
| 0.120 | Neurogenic Inflammation | NA | CTD_human | Detail | |
| <0.001 | CARCINOMA OF VULVA | NA | BeFree | Detail | |
| <0.001 | Hashimoto Disease | NA | BeFree | Detail | |
| 0.001 | Gastro-esophageal reflux disease with esophagitis | NA | BeFree | Detail | |
| 0.008 | Epithelial ovarian cancer | NA | BeFree,GAD | Detail | |
| 0.001 | invasive cancer | NA | BeFree | Detail | |
| <0.001 | Progressive Neoplastic Disease | NA | BeFree | Detail | |
| 0.018 | Carcinoma of lung | Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug re... | BeFree | 24909729 | Detail |
| 0.018 | Carcinoma of lung | Moreover, downregulation of COX-2/PGE2 and MIG-7 significantly prolonged the ove... | BeFree | 25004182 | Detail |
| 0.018 | Carcinoma of lung | A new class of compounds targeting cyclooxygenase 2 (COX-2) together with other ... | BeFree | 25113252 | Detail |
| 0.018 | Carcinoma of lung | The obtained results highlight the importance of the genes STAT5B and COX-2 in l... | BeFree | 25137041 | Detail |
| 0.018 | Carcinoma of lung | Silencing of USP22 downregulated COX-2, decreased its half-life, and inhibited l... | BeFree | 25817787 | Detail |
| 0.004 | Malignant neoplasm of gastrointestinal tract | To evaluate relationship between the cyclooxygenase-2 promoter 765G/C polymorphi... | BeFree | 24969885 | Detail |
| 0.005 | Secondary malignant neoplasm of lymph node | As a consequence, the expression of COX-2 and PCNA was found in cancer tissues w... | BeFree | 24992958 | Detail |
| 0.005 | Secondary malignant neoplasm of lymph node | The COX-2(+)/EGFR(+) group was associated with tumor size (p=0.002), mitotic ind... | BeFree | 25964576 | Detail |
| 0.033 | colon carcinoma | Our study confirmed that individuals who carried the polymorphisms that could af... | BeFree | 24998576 | Detail |
| 0.033 | colon carcinoma | Induction of COX-2 expression required live bacteria and was not due to colibact... | BeFree | 25545478 | Detail |
| 0.033 | colon carcinoma | Furthermore, cycling hypoxia-specific inflammatory phenotype, characterized by a... | BeFree | 25622900 | Detail |
| 0.031 | stomach carcinoma | We confirm loss of ANXA1 and overexpression of COX-2 in clinical gastric cancer,... | BeFree | 25038797 | Detail |
| 0.031 | stomach carcinoma | Cyclooxygenase 2 in gastric carcinoma is expressed in doublecortin- and CaM kina... | BeFree | 25228975 | Detail |
| 0.031 | stomach carcinoma | In this review, we present the latest clinical and experimental evidence showing... | BeFree | 25278683 | Detail |
| 0.031 | stomach carcinoma | This meta-analysis suggested that the -765G>C polymorphism of the COX-2 gene is ... | BeFree | 25339021 | Detail |
| 0.031 | stomach carcinoma | Cox2 CRAds with 5/3 chimeric-fiber modification, therefore, appear to be a promi... | BeFree | 26408678 | Detail |
| 0.006 | Carcinoma of bladder | These results suggest that miR‑101 may provide a novel mechanism for understandi... | BeFree | 25109742 | Detail |
| 0.006 | Carcinoma of bladder | ART efficiently inhibited orthotopic tumor growth in the bladder cancer rat, whi... | BeFree | 25196524 | Detail |
| 0.006 | Carcinoma of bladder | In bladder cancer cell lines, cyclosporine A (CsA) and tacrolimus (FK506), immun... | BeFree | 25638160 | Detail |
| 0.006 | skin carcinoma | Genetic polymorphisms in genes encoding the prednisolone receptor, GST enzyme, M... | BeFree,GAD | 25616102 | Detail |
| <0.001 | airway disease | NA | BeFree | Detail | |
| 0.003 | Central neuroblastoma | The secretion of IL-1β from glioblastoma cells in turn stimulates the expression... | BeFree | 24621265 | Detail |
| 0.003 | Central neuroblastoma | Gain and loss of β-catenin function, PGE2 , the adenylyl cyclase activator forsk... | BeFree | 25266063 | Detail |
| <0.001 | Punctate inner choroidopathy | NA | BeFree | Detail | |
| 0.001 | bile duct carcinoma | NA | BeFree | Detail | |
| <0.001 | Middle Cerebral Artery Occlusion | NA | BeFree | Detail | |
| <0.001 | Poorly differentiated carcinoma | NA | BeFree | Detail | |
| <0.001 | gastritis h pylori | NA | BeFree | Detail | |
| <0.001 | polyp benign | NA | BeFree | Detail | |
| 0.003 | biliary tract cancer | NA | BeFree,GAD | Detail | |
| <0.001 | Cancer of Digestive System | The -765G>C polymorphism in the cyclooxygenase-2 gene and digestive system cance... | BeFree | 25339021 | Detail |
| <0.001 | Idiopathic Inflammatory Myopathies | NA | BeFree | Detail | |
| <0.001 | Well Differentiated Oligodendroglioma | NA | BeFree | Detail | |
| <0.001 | Genitourinary Cancer | NA | BeFree | Detail | |
| <0.001 | Carotid Artery Plaque | NA | BeFree | Detail | |
| <0.001 | lymphangioleiomyomatosis | NA | BeFree | Detail | |
| <0.001 | Malignant Squamous Cell Neoplasm | NA | BeFree | Detail | |
| <0.001 | Lewy Body Disease | NA | BeFree | Detail | |
| <0.001 | Aicardi-Goutieres syndrome 1 | NA | BeFree | Detail | |
| 0.005 | Helicobacter pylori infection | NA | BeFree | Detail | |
| <0.001 | Invasive breast carcinoma | To comprehensively analyze the effects of cannabidiolic acid (CBDA), a selective... | BeFree | 25242400 | Detail |
| <0.001 | Rhabdoid Tumor of the Kidney | NA | BeFree | Detail | |
| <0.001 | Testicular malignant germ cell tumor | NA | BeFree | Detail | |
| <0.001 | Endothelial dysfunction | Pharmacological inhibition of cyclooxygenase-2 (COX-2) but not COX-1 prevented e... | BeFree | 24328731 | Detail |
| <0.001 | breast adenocarcinoma | Apoptotic effects of two COX-2 inhibitors on breast adenocarcinoma cells through... | BeFree | 25142612 | Detail |
| 0.120 | Drug-Induced Liver Injury | NA | CTD_human | Detail | |
| <0.001 | latent infection | NA | BeFree | Detail | |
| <0.001 | Enzyme inhibition disorder | Taken together, the results obtained here demonstrated that i) CBDA had dual inh... | BeFree | 25242400 | Detail |
| 0.001 | Intraepithelial Neoplasia | NA | BeFree | Detail | |
| 0.120 | Cardiomyopathies | NA | CTD_human | Detail | |
| <0.001 | Stromal Neoplasm | NA | BeFree | Detail | |
| 0.003 | Cerebral Ischemia | NA | BeFree,GAD | Detail | |
| <0.001 | Cerebral Aneurysm | In cerebral arteries, proinflammatory molecules, including tumor necrosis factor... | BeFree | 25922506 | Detail |
| 0.020 | ovarian neoplasm | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | autoimmune thyroiditis | NA | BeFree,LHGDN | Detail | |
| <0.001 | Metastatic Prostate Carcinoma | NA | BeFree | Detail | |
| 0.002 | precancerous lesions | NA | BeFree | Detail | |
| 0.003 | cholecystolithiasis | NA | BeFree,GAD | Detail | |
| <0.001 | Vascular inflammations | NA | BeFree | Detail | |
| 0.002 | Ischemic stroke | NA | BeFree | Detail | |
| 0.011 | Acute coronary syndrome | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Ovarian adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Colorectal cancer metastatic | NA | BeFree | Detail | |
| 0.001 | Polyp of large intestine | NA | BeFree | Detail | |
| <0.001 | Hurthle Cell Tumor | NA | BeFree | Detail | |
| <0.001 | Spondylarthropathies | NA | BeFree | Detail | |
| 0.080 | Arthritis, Experimental | NA | RGD | Detail | |
| 0.122 | Invasive Ductal Breast Carcinoma | Immunohistochemistry was performed to assess co-expression of α3 and COX2 in spe... | BeFree,CTD_human | 24950714 | Detail |
| 0.010 | Malignant neoplasm of ovary | These findings provided a theoretical basis for determining the function of COX-... | BeFree,GAD | 25335121 | Detail |
| 0.002 | endometrial adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | High-Grade Prostatic Intraepithelial Neoplasia | NA | BeFree | Detail | |
| 0.127 | Squamous cell carcinoma of the head and neck | Association between cyclooxygenase-2 gene polymorphisms and head and neck squamo... | BeFree,CTD_human | 24469360 | Detail |
| 0.006 | Ductal Carcinoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Myxoid cyst | NA | BeFree | Detail | |
| <0.001 | Rhinorrhea | NA | BeFree | Detail | |
| <0.001 | Drusen | NA | BeFree | Detail | |
| 0.004 | sarcoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Traditional Serrated Adenoma | NA | BeFree | Detail | |
| <0.001 | major depressive disorder | NA | BeFree | Detail | |
| 0.003 | Inflammatory disorder | Cyclooxygenase-2 (COX-2) is an inducible enzyme converting arachidonic acid to p... | BeFree,GAD | 24733273 | Detail |
| <0.001 | Primary Effusion Lymphoma | Here, we investigate the role of Nrf2 in PEL and PEL-derived cell lines and show... | BeFree | 25995248 | Detail |
| <0.001 | Precursor B-cell lymphoblastic leukemia | NA | BeFree | Detail | |
| <0.001 | Pancreatic intraepithelial neoplasia | NA | BeFree | Detail | |
| 0.007 | Adenoma of large intestine | NA | BeFree | Detail | |
| <0.001 | Eosinophilic disorder | NA | BeFree | Detail | |
| <0.001 | M5b Acute differentiated monocytic leukemia | The present study aimed to investigate the mechanism by which O. japonicus extra... | BeFree | 25760396 | Detail |
| 0.001 | Adenocarcinoma of large intestine | Expression of cyclooxygenase-2 (COX-2) in colorectal adenocarcinoma: an immunohi... | BeFree | 25169526 | Detail |
| 0.120 | Asthma, Aspirin-Induced | NA | CTD_human | Detail | |
| <0.001 | Barrett's adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Esophageal Squamous Intraepithelial Neoplasia | NA | BeFree | Detail | |
| <0.001 | gastric cardia adenocarcinoma | NA | BeFree | Detail | |
| 0.001 | Hereditary Nonpolyposis Colorectal Cancer | NA | BeFree | Detail | |
| <0.001 | Invasive Carcinoma | NA | BeFree | Detail | |
| <0.001 | Mucinous Neoplasm | Expression of IL-1, TNF-α and COX-2 increased with the stage of the disease in b... | BeFree | 25007180 | Detail |
| <0.001 | Ovarian Serous Adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | pancreatic ductal adenocarcinoma | In conclusion, we were able to delineate a novel c-Rel-, NFATc2- and COX-2-depen... | BeFree | 25299780 | Detail |
| <0.001 | Hypopharyngeal Carcinoma | NA | BeFree | Detail | |
| <0.001 | Epithelioma | NA | BeFree | Detail | |
| <0.001 | Oncocytic Neoplasm | NA | BeFree | Detail | |
| 0.002 | hearing impairment | NA | GAD | Detail | |
| <0.001 | Posterior capsule opacification | Downregulation of fibronectin, Slug, and cyclooxygenase-2 (COX-2) expression and... | BeFree | 25626972 | Detail |
| <0.001 | Cardiomyopathy, Familial Idiopathic | COX2 and α3 are correlated in IDC independently of hormone receptor status or ot... | BeFree | 24950714 | Detail |
| 0.205 | Mammary Neoplasms | NA | BeFree,CTD_human,LHGDN | Detail | |
| <0.001 | Diverticulosis | In macroscopically undamaged acute DD mucosa, the opposite findings were seen: f... | BeFree | 25666316 | Detail |
| <0.001 | oxyphilic adenoma | NA | BeFree | Detail | |
| <0.001 | Angiogenic Switch | NA | BeFree | Detail | |
| <0.001 | Breast Cancer Model | Our previously published work in a preclinical breast cancer model showed that i... | BeFree | 24950714 | Detail |
| 0.003 | Hepatocarcinogenesis | Prostaglandin E2 (PGE2), the predominant product of cyclooxygenase-2, has been i... | BeFree | 25109834 | Detail |
| <0.001 | Cervical high grade squamous intraepithelial lesion | NA | BeFree | Detail | |
| <0.001 | Mammary Tumorigenesis | NA | BeFree | Detail | |
| 0.001 | Cancer Cell Growth | NA | BeFree | Detail | |
| <0.001 | Neuropathogenesis | NA | BeFree | Detail | |
| <0.001 | Skin Carcinogenesis | NA | BeFree | Detail | |
| 0.007 | Tumor Angiogenesis | NA | BeFree | Detail | |
| 0.002 | Tumor Promotion | NA | BeFree | Detail | |
| 0.002 | Xenograft Model | NA | BeFree | Detail | |
| 0.094 | colorectal cancer | Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug... | BeFree,GAD | 23543356 | Detail |
| 0.094 | colorectal cancer | Meta-analysis of the association between COX-2 polymorphisms and risk of colorec... | BeFree,GAD | 24733273 | Detail |
| 0.094 | colorectal cancer | No significant liver cancer and colorectal cancer risk of COX-2 -765G/C polymorp... | BeFree,GAD | 24969885 | Detail |
| 0.094 | colorectal cancer | Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes an... | BeFree,GAD | 24998576 | Detail |
| 0.094 | colorectal cancer | Thus, both PTGS2 polymorphisms and PTGS2 mRNA levels may provide information reg... | BeFree,GAD | 25166592 | Detail |
| 0.094 | colorectal cancer | These findings provide further indication that postdiagnosis aspirin therapy imp... | BeFree,GAD | 25239119 | Detail |
| 0.094 | colorectal cancer | These findings indicate that miR-21 is a component of the COX-2 inflammation pat... | BeFree,GAD | 25310697 | Detail |
| 0.094 | colorectal cancer | We expect that paeonol may replace selective COX-2 inhibitors due to their toxic... | BeFree,GAD | 25322760 | Detail |
| 0.094 | colorectal cancer | STIM1 overexpression promotes colorectal cancer progression, cell motility and C... | BeFree,GAD | 25381814 | Detail |
| 0.094 | colorectal cancer | These results imply that miR-1297 has the potential to provide a new approach to... | BeFree,GAD | 25422199 | Detail |
| 0.094 | colorectal cancer | Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase ... | BeFree,GAD | 25818893 | Detail |
| 0.094 | colorectal cancer | Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal c... | BeFree,GAD | 25835114 | Detail |
| 0.094 | colorectal cancer | Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and N... | BeFree,GAD | 26220687 | Detail |
| <0.001 | Rash and Dermatitis Adverse Event Associated with Chemoradiation | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma, Endometrioid | NA | BeFree | Detail | |
| 0.001 | Cirrhosis | NA | BeFree | Detail | |
| <0.001 | Disorder characterized by eosinophilia | NA | BeFree | Detail | |
| <0.001 | androgen independent prostate cancer | NA | BeFree | Detail | |
| 0.002 | Benign Prostatic Hyperplasia | NA | BeFree | Detail | |
| <0.001 | Endometrial Polyp | NA | BeFree | Detail | |
| <0.001 | Eccrine carcinoma | NA | BeFree | Detail | |
| <0.001 | Invasive Prostate Carcinoma | NA | BeFree | Detail | |
| <0.001 | Keratocystic Odontogenic Tumor | Expression of human papillomavirus is correlated with Ki-67 and COX-2 expression... | BeFree | 24831259 | Detail |
| 0.002 | Non-Neoplastic Disorder | NA | BeFree | Detail | |
| <0.001 | Meningioma, benign, no ICD-O subtype | NA | BeFree | Detail | |
| 0.005 | Idiopathic Pulmonary Fibrosis | NA | BeFree,GAD | Detail | |
| <0.001 | Malformations of Cortical Development, Group II | Importantly, ectopically expressed COX-2 or exogenous PGE2 were able to rescue m... | BeFree | 25381814 | Detail |
| <0.001 | SPEECH-SOUND DISORDER | SSD treatment inhibited STAT3 activation [phosphorylation of STAT3 (p‑STAT3)], r... | BeFree | 25231214 | Detail |
| 0.001 | IMMUNE SUPPRESSION | NA | BeFree | Detail | |
| <0.001 | VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | NA | BeFree | Detail | |
| <0.001 | Corneal dystrophy, Fuchs' endothelial, 1 | NA | BeFree | Detail | |
| <0.001 | Creutzfeldt-Jakob Disease, Sporadic | NA | BeFree | Detail | |
| <0.001 | CATARACT, ANTERIOR POLAR | Downregulation of fibronectin, Slug, and cyclooxygenase-2 (COX-2) expression and... | BeFree | 25626972 | Detail |
| 0.132 | coronary artery disease | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Vasculitic neuropathy | NA | BeFree | Detail | |
| <0.001 | Transformed migraine | NA | BeFree | Detail | |
| 0.002 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | GAD | Detail | |
| <0.001 | Urothelial Carcinoma | NA | BeFree | Detail | |
| 0.080 | Ventilator-Induced Lung Injury | NA | RGD | Detail | |
| 0.080 | Acute kidney injury | NA | RGD | Detail | |
| <0.001 | FAMILIAL ADENOMATOUS POLYPOSIS, ATTENUATED (disorder) | NA | BeFree | Detail | |
| 0.002 | Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified | NA | GAD | Detail | |
| 0.001 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
| <0.001 | Plaque, Amyloid | NA | BeFree | Detail | |
| 0.080 | Cerebral Hemorrhage | NA | RGD | Detail | |
| <0.001 | aggressive cancer | NA | BeFree | Detail | |
| <0.001 | Early-Stage Breast Carcinoma | NA | BeFree | Detail | |
| <0.001 | Stage II Colon Cancer AJCC v7 | NA | BeFree | Detail | |
| <0.001 | Stage III Breast Cancer AJCC v7 | NA | BeFree | Detail | |
| 0.002 | Ischemic Cerebrovascular Accident | NA | BeFree | Detail | |
| <0.001 | Poorly Differentiated Hepatocellular Carcinoma | NA | BeFree | Detail | |
| <0.001 | Proliferative Inflammatory Atrophy | NA | BeFree | Detail | |
| <0.001 | Reflux nephropathy (disorder) | NA | BeFree | Detail | |
| <0.001 | Progressive cGVHD | NA | BeFree | Detail | |
| 0.019 | Infection | NA | GAD,LHGDN | Detail | |
| 0.003 | Experimental Organism Basal Cell Carcinoma | NA | BeFree | Detail | |
| <0.001 | Diminished ovarian reserve | NA | BeFree | Detail | |
| 0.002 | Hearing Loss | NA | GAD | Detail | |
| <0.001 | acute pancreatitis | NA | BeFree | Detail | |
| 0.298 | adenocarcinoma | COX-2 overexpression in resected pancreatic head adenocarcinomas correlates with... | BeFree,CTD_human,GAD,LHGDN,RGD | 24950702 | Detail |
| 0.298 | adenocarcinoma | We examined the association between COX-2 and DCAMKL1 expression in gastric carc... | BeFree,CTD_human,GAD,LHGDN,RGD | 25228975 | Detail |
| 0.049 | adenoma | PTGS2 mRNA levels were higher in mild/moderate adenoma tissue compared to morpho... | BeFree,GAD,LHGDN | 25166592 | Detail |
| 0.049 | adenoma | Loss of IHH from Apc(HET) mice changed the composition of the adenoma stroma; ce... | BeFree,GAD,LHGDN | 25307863 | Detail |
| 0.049 | adenoma | Serum adiponectin concentrations, and the mRNA and protein expression of adipone... | BeFree,GAD,LHGDN | 25370174 | Detail |
| <0.001 | Postoperative adhesion | NA | BeFree | Detail | |
| 0.120 | Adrenal Gland Neoplasms | NA | CTD_human | Detail | |
| <0.001 | AIDS Dementia Complex | NA | BeFree | Detail | |
| 0.120 | Albuminuria | NA | CTD_human | Detail | |
| 0.101 | Alzheimer's disease | Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulati... | BeFree,GAD,LHGDN,RGD | 24621265 | Detail |
| 0.101 | Alzheimer's disease | This study shows that 24-hydroxycholesterol, 27-hydroxycholesterol, and 7β-hydro... | BeFree,GAD,LHGDN,RGD | 24802026 | Detail |
| 0.080 | retrograde amnesia | NA | RGD | Detail | |
| <0.001 | Amputation Stumps | NA | BeFree | Detail | |
| 0.124 | amyotrophic lateral sclerosis | Taken together, our results reveal a previously unrecognized non-cell-autonomous... | BeFree,CTD_human,GAD | 25811799 | Detail |
| 0.080 | anaphylaxis | NA | RGD | Detail | |
| <0.001 | Anemia, Hemolytic | NA | BeFree | Detail | |
| <0.001 | Aneurysm | NA | BeFree | Detail | |
| 0.011 | Anoxia | NA | GAD,LHGDN | Detail | |
| <0.001 | anthracosis | Polymorphisms in cyclooxygenase-2 gene and risk of developing coal workers' pneu... | BeFree | 24899082 | Detail |
| <0.001 | Anxiety Disorders | NA | BeFree | Detail | |
| <0.001 | aortic aneurysm | NA | BeFree | Detail | |
| 0.120 | Cardiac arrhythmia | NA | CTD_human | Detail | |
| 0.004 | arteriosclerosis | NA | BeFree | Detail | |
| <0.001 | Arthralgia | NA | BeFree | Detail | |
| 0.003 | arthritis | NA | BeFree | Detail | |
| 0.001 | Arthritis, Adjuvant-Induced | Paederia foetida Linn. inhibits adjuvant induced arthritis by suppression of PGE... | BeFree | 25893742 | Detail |
| <0.001 | Arthritis, Psoriatic | NA | BeFree | Detail | |
| 0.136 | rheumatoid arthritis | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.120 | asphyxia neonatorum | NA | CTD_human | Detail | |
| 0.102 | asthma | NA | BeFree,GAD,LHGDN,RGD | Detail | |
| 0.006 | Astrocytoma | NA | BeFree,LHGDN | Detail | |
| 0.139 | atherosclerosis | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.125 | autistic disorder | NA | CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Autoimmune Diseases | Cyclooxygenase-2 (COX-2) is an inducible enzyme that catalyzes prostaglandins th... | BeFree | 24469360 | Detail |
| <0.001 | Melanoma, B16 | NA | BeFree | Detail | |
| <0.001 | Bacteremia | NA | BeFree | Detail | |
| 0.004 | Bacterial Infections | The poor metabolic potential of HeLa, mainly concerning FADS2 upstream of COX-2 ... | BeFree,LHGDN | 25549244 | Detail |
| 0.209 | Barrett esophagus | NA | BeFree,CTD_human,GAD,LHGDN,RGD | Detail | |
| 0.003 | Bile Duct Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | bile reflux | NA | BeFree | Detail | |
| 0.018 | Malignant neoplasm of urinary bladder | These results suggest that miR‑101 may provide a novel mechanism for understandi... | BeFree,GAD | 25109742 | Detail |
| 0.018 | Malignant neoplasm of urinary bladder | ART efficiently inhibited orthotopic tumor growth in the bladder cancer rat, whi... | BeFree,GAD | 25196524 | Detail |
| 0.018 | Malignant neoplasm of urinary bladder | In bladder cancer cell lines, cyclosporine A (CsA) and tacrolimus (FK506), immun... | BeFree,GAD | 25638160 | Detail |
| 0.120 | bladder neck obstruction | NA | CTD_human | Detail | |
| 0.125 | Bladder Neoplasm | NA | CTD_human,LHGDN | Detail | |
| <0.001 | Bloom syndrome | In IL-32-induced macrophages, the production of IL-1β, IL-6, IL-8, and TNF-α, an... | BeFree | 25089715 | Detail |
| <0.001 | Body Temperature Changes | NA | BeFree | Detail | |
| 0.120 | Bone neoplasms | NA | CTD_human | Detail | |
| <0.001 | borderline personality disorder | NA | BeFree | Detail | |
| 0.002 | Bronchiolitis, Viral | NA | GAD | Detail | |
| <0.001 | bronchopulmonary dysplasia | NA | BeFree | Detail | |
| <0.001 | bursitis | NA | BeFree | Detail | |
| 0.120 | Cachexia | NA | CTD_human | Detail | |
| 0.033 | Malignant tumor of colon | Our study confirmed that individuals who carried the polymorphisms that could af... | BeFree,GAD | 24998576 | Detail |
| 0.033 | Malignant tumor of colon | Induction of COX-2 expression required live bacteria and was not due to colibact... | BeFree,GAD | 25545478 | Detail |
| 0.033 | Malignant tumor of colon | Furthermore, cycling hypoxia-specific inflammatory phenotype, characterized by a... | BeFree,GAD | 25622900 | Detail |
| <0.001 | Malignant neoplasm of larynx | Experimental data showed upregulation of the selected EGFR cascade in tumor cell... | BeFree | 25736926 | Detail |
| 0.001 | Adenocarcinoma of prostate | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of skin | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of thyroid | NA | BeFree | Detail | |
| 0.008 | basal cell carcinoma | NA | GAD,LHGDN | Detail | |
| <0.001 | Bronchogenic Carcinoma | NA | BeFree | Detail | |
| 0.005 | Noninfiltrating Intraductal Carcinoma | NA | BeFree,LHGDN | Detail | |
| 0.020 | Non-small cell lung carcinoma | Similarly, miR-17-92 levels are significantly elevated in NSCLC cells ectopicall... | BeFree,LHGDN | 24469837 | Detail |
| 0.020 | Non-small cell lung carcinoma | COX-2 overexpression and -8473 T/C polymorphism in 3' UTR in non-small cell lung... | BeFree,LHGDN | 25113252 | Detail |
| 0.020 | Non-small cell lung carcinoma | Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathologica... | BeFree,LHGDN | 25137041 | Detail |
| 0.020 | Non-small cell lung carcinoma | Hu-antigen receptor (HuR) and cyclooxygenase-2 (COX-2) expression in human non-s... | BeFree,LHGDN | 25252849 | Detail |
| 0.020 | Non-small cell lung carcinoma | Cyclooxygenase-2 genetic variants influence intratumoral infiltration of Foxp3-p... | BeFree,LHGDN | 25338928 | Detail |
| 0.020 | Non-small cell lung carcinoma | Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compar... | BeFree,LHGDN | 25449785 | Detail |
| 0.020 | Non-small cell lung carcinoma | USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non... | BeFree,LHGDN | 25817787 | Detail |
| 0.020 | Non-small cell lung carcinoma | The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome o... | BeFree,LHGDN | 25975224 | Detail |
| 0.020 | Non-small cell lung carcinoma | The current study investigated EGFR and COX-2 inhibition in patients with non-sm... | BeFree,LHGDN | 26033830 | Detail |
| 0.001 | Carcinoma, Papillary | NA | BeFree | Detail | |
| 0.207 | renal cell carcinoma | NA | BeFree,CTD_human,LHGDN,RGD | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In the Chinese subgroup, nominally significant associations were shown between (i) EBBR2+1963G (rs18... | DisGeNET | Detail |
| In the Chinese subgroup, nominally significant associations were shown between (i) EBBR2+1963G (rs18... | DisGeNET | Detail |
| In the Chinese subgroup, nominally significant associations were shown between (i) EBBR2+1963G (rs18... | DisGeNET | Detail |
| Association of cyclooxygenase-2 genetic variant with cardiovascular disease. | DisGeNET | Detail |
| Homocysteine and pro-inflammatory mediators such as cyclooxygenase-2 (COX-2) have been linked to vas... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our study for the first time demonstrated differential expression of the PGE2-related enzymes COX-2 ... | DisGeNET | Detail |
| (i) Endoscopically normal appearing colonic mucosa of patients with UC-IR remains abnormal: CLE demo... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug resistance through ... | DisGeNET | Detail |
| Meta-analysis of the association between COX-2 polymorphisms and risk of colorectal cancer based on ... | DisGeNET | Detail |
| No significant liver cancer and colorectal cancer risk of COX-2 -765G/C polymorphism was found. | DisGeNET | Detail |
| Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer ... | DisGeNET | Detail |
| Thus, both PTGS2 polymorphisms and PTGS2 mRNA levels may provide information regarding CRC risk. | DisGeNET | Detail |
| Our data suggest overexpression of COX-2 protein in colorectal carcinoma in contrast to normal mucos... | DisGeNET | Detail |
| These findings provide further indication that postdiagnosis aspirin therapy improved CRC overall su... | DisGeNET | Detail |
| These findings indicate that miR-21 is a component of the COX-2 inflammation pathway and that this p... | DisGeNET | Detail |
| We expect that paeonol may replace selective COX-2 inhibitors due to their toxic effects, and may of... | DisGeNET | Detail |
| STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression. | DisGeNET | Detail |
| These results imply that miR-1297 has the potential to provide a new approach to colorectal cancer t... | DisGeNET | Detail |
| Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase 2) have reported to ... | DisGeNET | Detail |
| Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal cancer and polyps amo... | DisGeNET | Detail |
| Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-κB signalings in c... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impairment in individuals... | DisGeNET | Detail |
| Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impairment in individuals... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results support the hypothesis that T2D pathology contributes in vivo to increase the inflammato... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| The amount of indoleamine 2,3-dioxygenase-1 (IDO1) and cyclooxygenase-2 (COX-2) in E-MenSCs co-cultu... | DisGeNET | Detail |
| Genetic variation in COX-2 -1195 and the risk of endometriosis and adenomyosis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Fried... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| More importantly, Aβ deposition mediated the inflammatory response of glial cells via inducing the e... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Through glycolysis and arachidonic acid metabolism, HK3 and PTGS2 might play important roles in pedi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| Effect of a single nucleotide polymorphism in miR-146a on COX-2 protein expression and lung function... | DisGeNET | Detail |
| This shows that COX-2 activity is present during lung tumor development in a high HGF environment. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We confirm loss of ANXA1 and overexpression of COX-2 in clinical gastric cancer, suggesting that the... | DisGeNET | Detail |
| In this review, we present the latest clinical and experimental evidence showing the role of gastrin... | DisGeNET | Detail |
| This meta-analysis suggested that the -765G>C polymorphism of the COX-2 gene is a potential risk fac... | DisGeNET | Detail |
| Cox2 CRAds with 5/3 chimeric-fiber modification, therefore, appear to be a promising imaging and the... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To comprehensively analyze the effects of cannabidiolic acid (CBDA), a selective COX-2 inhibitor fou... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| AMI-1 inhibited the expression of COX2 in TGF-β-stimulated cells. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To investigate whether single nucleotide polymorphisms (SNPs) of eicosanoid biosynthesis genes are a... | DisGeNET | Detail |
| To investigate whether single nucleotide polymorphisms (SNPs) of eicosanoid biosynthesis genes are a... | DisGeNET | Detail |
| Gene expression analysis showed that several genes involved in tumor development and metastasis (EGR... | DisGeNET | Detail |
| The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenuation of epithelial-m... | DisGeNET | Detail |
| Co-expression of cancer COX-2 and stromal IDO predicts a worse disease-free and metastasis-free surv... | DisGeNET | Detail |
| Taken together, the results obtained here demonstrated that i) CBDA had dual inhibitory effects on C... | DisGeNET | Detail |
| Hu-antigen R (HuR) is considered to play a central role in tumor formation, growth, and metastasis b... | DisGeNET | Detail |
| Our studies also suggested a new approach to inhibit STIM1-mediated metastasis with COX-2 inhibitors... | DisGeNET | Detail |
| Univariate analysis showed that COX-2 protein expression was associated with shorter disease-free su... | DisGeNET | Detail |
| Cyclooxygenase-2 (COX-2) and interleukin-8 (IL-8) are two highly expressed inflammatory mediators to... | DisGeNET | Detail |
| Elevated expression of cyclooxygenase-2 (COX-2) is observed in many human cancers and over-productio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The secretion of IL-1β from glioblastoma cells in turn stimulates the expression of COX-2 in human o... | DisGeNET | Detail |
| Gain and loss of β-catenin function, PGE2 , the adenylyl cyclase activator forskolin and pharmacolog... | DisGeNET | Detail |
| Overall, this work suggests that COX-2 is a key modulator in VS cell proliferation and survival and ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In conclusion, our results point to COX-2 as a potential therapeutic target against obesity-associat... | DisGeNET | Detail |
| Investigation regarding the efficacy of a COX-2 inhibitor/aromatase inhibitor combination therapy in... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Using rabbit and human synovial fibroblast cell lines, we examined the effects of Cx43 overexpressio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These findings provided a theoretical basis for determining the function of COX-2 in the development... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| At the same location of pain assessment and fibroblast sampling, in situ immunohistochemical (IHC)(+... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| However, susceptibility genes, such as CDKN2BAS (Cyclin Dependend KiNase 2B AntiSense RNA; alias ANR... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The association between single-nucleotide polymorphisms in cyclooxygenase-2 gene with pneumoconiosis... | DisGeNET | Detail |
| PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibrobl... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal cancer and polyps amo... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Taken together, our findings indicated that mycobacterial HtdY might contribute to the persistence o... | DisGeNET | Detail |
| We recently reported that prostaglandin biosynthesis and cyclooxygenase-2 were deregulated in TSC an... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| This study aimed to determine the significance of CTNNB1 (β-catenin) mutations in predicting the tre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Compound 5f exhibited moderate cytotoxicity with 58.79% growth inhibition against SNB-75 (CNS Cancer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| AMI-1 inhibited the expression of COX2 in TGF-β-stimulated cells. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cholangiocarcinogenesis and tumor progression are regulated by a novel interplay between COX-2/PGE2 ... | DisGeNET | Detail |
| Macrophages are one of the predominant tumor-infiltrating immune cells supporting key processes in t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In parallel, cyclooxygenase-2 (COX2) overexpression and PGE2 treatment increased miR-21 levels and e... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results suggest the COX2-MMP1/CCL7 axis as a novel therapeutic target for brain metastasis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Immunohistochemistry staining showed COX-2 in pancreatic carcinoma cells, but not in stromal cells. | DisGeNET | Detail |
| COX-2 is overexpressed in pancreatic cancer, ampullary cancer and distal bile duct cancer and confer... | DisGeNET | Detail |
| These findings suggest that COX-2-765*C is related to cancer susceptibility and may increase gastric... | DisGeNET | Detail |
| Studies of the molecular pathology of pancreatic cancer have revealed that activation of KRAS, overe... | DisGeNET | Detail |
| Significant inhibition of VEGF, angiopoietin 1, angiopoietin 2, platelet derived growth factor, COX-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Combined immunohistochemical evaluation of the levels of COX-2, MMP-9 and VEGF in PTC might be a use... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (... | DisGeNET | Detail |
| Moreover, downregulation of COX-2/PGE2 and MIG-7 significantly prolonged the overall and disease-fre... | DisGeNET | Detail |
| A new class of compounds targeting cyclooxygenase 2 (COX-2) together with other different clinically... | DisGeNET | Detail |
| The obtained results highlight the importance of the genes STAT5B and COX-2 in lung cancer progressi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our aims were to replicate some previously reported associations of single nucleotide polymorphisms ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cyclooxygenase-2 inhibition as a strategy for treating gastric adenocarcinoma. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The protein levels of STAT3, phosphorylated STAT3, VEGF, NF-κB p65, phosphorylated NF-κB p65 and COX... | DisGeNET | Detail |
| Overexpression of phospholipase A2 Group IIA in esophageal squamous cell carcinoma and association w... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A new class of compounds targeting cyclooxygenase 2 (COX-2) together with other different clinically... | DisGeNET | Detail |
| The cyclooxygenase-2 (COX-2) enzyme and major lipid product, prostaglandin E2 (PGE2) are elevated in... | DisGeNET | Detail |
| The enzyme cyclooxygenase 2 is an inducible enzyme expressed at sites of inflammation and in a varie... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Furthermore, using selective COX-2 inhibitors to prevent intra-abdominal adhesions did not adversely... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In vitro studies in colonic adenocarcinoma cells revealed that treatment with the selective COX-2 in... | DisGeNET | Detail |
| Association between polymorphism c.1-765G>C of the COX2 gene and cognitive impairment in individuals... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| AMI-1 inhibited the expression of COX2 in TGF-β-stimulated cells. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Genetic variation in COX-2 -1195 and the risk of endometriosis and adenomyosis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic activity and risk of es... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The aim of the present study was to examine expression of COX-2 in cancer cells and stromal cells in... | DisGeNET | Detail |
| COX-2 is overexpressed in pancreatic cancer, ampullary cancer and distal bile duct cancer and confer... | DisGeNET | Detail |
| These findings suggest that COX-2-765*C is related to cancer susceptibility and may increase gastric... | DisGeNET | Detail |
| Studies of the molecular pathology of pancreatic cancer have revealed that activation of KRAS, overe... | DisGeNET | Detail |
| Significant inhibition of VEGF, angiopoietin 1, angiopoietin 2, platelet derived growth factor, COX-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Compound 5f exhibited moderate cytotoxicity with 58.79% growth inhibition against SNB-75 (CNS Cancer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We recently reported that prostaglandin biosynthesis and cyclooxygenase-2 were deregulated in TSC an... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We found that FYN increased COX2 activity in prostate cancer cells DU145, independent of changes in ... | DisGeNET | Detail |
| Analysis of inflammatory genes in the patient tissues revealed that IL-6 expression was the highest ... | DisGeNET | Detail |
| Vasoactive intestinal peptide (VIP) exerts similar effects in prostate cancer models involving incre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our aims were to replicate some previously reported associations of single nucleotide polymorphisms ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| COX2 inhibition reduces aortic valve calcification in vivo. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Inhibition of cyclooxygenase-2 prevents intra-abdominal adhesions by decreasing activity of peritone... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Experimental data showed upregulation of the selected EGFR cascade in tumor cells, stromal expressio... | DisGeNET | Detail |
| Prostaglandins produced by Cyclooxygenase-2 enzyme have been implicated to have a role in breast car... | DisGeNET | Detail |
| Overexpression of cyclooxygenase-2 (COX-2) has been implicated in oncogenesis and progression of ade... | DisGeNET | Detail |
| It has been reported that COX-2 expression is associated with MMP-2 expression in thyroid and breast... | DisGeNET | Detail |
| Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model wi... | DisGeNET | Detail |
| Our data suggest overexpression of COX-2 protein in colorectal carcinoma in contrast to normal mucos... | DisGeNET | Detail |
| Helicobacter pylori infection, gastrin and cyclooxygenase-2 in gastric carcinogenesis. | DisGeNET | Detail |
| The aim of the present study was to investigate the effects of plasmid-mediated RNA interference tar... | DisGeNET | Detail |
| The present study aimed to investigate the role of the JAK/STAT3 pathway in the growth and cancer-re... | DisGeNET | Detail |
| Furthermore, miR-1297 could inhibit human colorectal cancer LOVO and HCT116 cell proliferation, migr... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The present study aimed to investigate the mechanism by which O. japonicus extract affects the expre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We found that FYN increased COX2 activity in prostate cancer cells DU145, independent of changes in ... | DisGeNET | Detail |
| Analysis of inflammatory genes in the patient tissues revealed that IL-6 expression was the highest ... | DisGeNET | Detail |
| Vasoactive intestinal peptide (VIP) exerts similar effects in prostate cancer models involving incre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (... | DisGeNET | Detail |
| Moreover, downregulation of COX-2/PGE2 and MIG-7 significantly prolonged the overall and disease-fre... | DisGeNET | Detail |
| A new class of compounds targeting cyclooxygenase 2 (COX-2) together with other different clinically... | DisGeNET | Detail |
| The obtained results highlight the importance of the genes STAT5B and COX-2 in lung cancer progressi... | DisGeNET | Detail |
| Silencing of USP22 downregulated COX-2, decreased its half-life, and inhibited lung carcinoma cell p... | DisGeNET | Detail |
| To evaluate relationship between the cyclooxygenase-2 promoter 765G/C polymorphism and digestive can... | DisGeNET | Detail |
| As a consequence, the expression of COX-2 and PCNA was found in cancer tissues with a higher strong ... | DisGeNET | Detail |
| The COX-2(+)/EGFR(+) group was associated with tumor size (p=0.002), mitotic index (p=0.019), histol... | DisGeNET | Detail |
| Our study confirmed that individuals who carried the polymorphisms that could affect the expressions... | DisGeNET | Detail |
| Induction of COX-2 expression required live bacteria and was not due to colibactin production, as si... | DisGeNET | Detail |
| Furthermore, cycling hypoxia-specific inflammatory phenotype, characterized by a simultaneous (bacul... | DisGeNET | Detail |
| We confirm loss of ANXA1 and overexpression of COX-2 in clinical gastric cancer, suggesting that the... | DisGeNET | Detail |
| Cyclooxygenase 2 in gastric carcinoma is expressed in doublecortin- and CaM kinase-like-1-positive t... | DisGeNET | Detail |
| In this review, we present the latest clinical and experimental evidence showing the role of gastrin... | DisGeNET | Detail |
| This meta-analysis suggested that the -765G>C polymorphism of the COX-2 gene is a potential risk fac... | DisGeNET | Detail |
| Cox2 CRAds with 5/3 chimeric-fiber modification, therefore, appear to be a promising imaging and the... | DisGeNET | Detail |
| These results suggest that miR‑101 may provide a novel mechanism for understanding cisplatin resista... | DisGeNET | Detail |
| ART efficiently inhibited orthotopic tumor growth in the bladder cancer rat, which is accompanied wi... | DisGeNET | Detail |
| In bladder cancer cell lines, cyclosporine A (CsA) and tacrolimus (FK506), immunosuppressant drugs/n... | DisGeNET | Detail |
| Genetic polymorphisms in genes encoding the prednisolone receptor, GST enzyme, MC1R, MTHFR enzyme an... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The secretion of IL-1β from glioblastoma cells in turn stimulates the expression of COX-2 in human o... | DisGeNET | Detail |
| Gain and loss of β-catenin function, PGE2 , the adenylyl cyclase activator forskolin and pharmacolog... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The -765G>C polymorphism in the cyclooxygenase-2 gene and digestive system cancer: a meta-analysis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To comprehensively analyze the effects of cannabidiolic acid (CBDA), a selective COX-2 inhibitor fou... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Pharmacological inhibition of cyclooxygenase-2 (COX-2) but not COX-1 prevented endothelial dysfuncti... | DisGeNET | Detail |
| Apoptotic effects of two COX-2 inhibitors on breast adenocarcinoma cells through COX-2 independent p... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Taken together, the results obtained here demonstrated that i) CBDA had dual inhibitory effects on C... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In cerebral arteries, proinflammatory molecules, including tumor necrosis factor-α, cyclooxygenase-2... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Immunohistochemistry was performed to assess co-expression of α3 and COX2 in specimens of human inva... | DisGeNET | Detail |
| These findings provided a theoretical basis for determining the function of COX-2 in the development... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association between cyclooxygenase-2 gene polymorphisms and head and neck squamous cell carcinoma ri... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cyclooxygenase-2 (COX-2) is an inducible enzyme converting arachidonic acid to prostaglandins and pl... | DisGeNET | Detail |
| Here, we investigate the role of Nrf2 in PEL and PEL-derived cell lines and show that KSHV latency i... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The present study aimed to investigate the mechanism by which O. japonicus extract affects the expre... | DisGeNET | Detail |
| Expression of cyclooxygenase-2 (COX-2) in colorectal adenocarcinoma: an immunohistochemical and hist... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression of IL-1, TNF-α and COX-2 increased with the stage of the disease in both serous and mucin... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In conclusion, we were able to delineate a novel c-Rel-, NFATc2- and COX-2-dependent antiapoptotic s... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Downregulation of fibronectin, Slug, and cyclooxygenase-2 (COX-2) expression and upregulation of E-c... | DisGeNET | Detail |
| COX2 and α3 are correlated in IDC independently of hormone receptor status or other clinicopathologi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In macroscopically undamaged acute DD mucosa, the opposite findings were seen: for both gene express... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our previously published work in a preclinical breast cancer model showed that integrin α3β1 promote... | DisGeNET | Detail |
| Prostaglandin E2 (PGE2), the predominant product of cyclooxygenase-2, has been implicated in hepatoc... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug resistance through ... | DisGeNET | Detail |
| Meta-analysis of the association between COX-2 polymorphisms and risk of colorectal cancer based on ... | DisGeNET | Detail |
| No significant liver cancer and colorectal cancer risk of COX-2 -765G/C polymorphism was found. | DisGeNET | Detail |
| Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer ... | DisGeNET | Detail |
| Thus, both PTGS2 polymorphisms and PTGS2 mRNA levels may provide information regarding CRC risk. | DisGeNET | Detail |
| These findings provide further indication that postdiagnosis aspirin therapy improved CRC overall su... | DisGeNET | Detail |
| These findings indicate that miR-21 is a component of the COX-2 inflammation pathway and that this p... | DisGeNET | Detail |
| We expect that paeonol may replace selective COX-2 inhibitors due to their toxic effects, and may of... | DisGeNET | Detail |
| STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression. | DisGeNET | Detail |
| These results imply that miR-1297 has the potential to provide a new approach to colorectal cancer t... | DisGeNET | Detail |
| Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase 2) have reported to ... | DisGeNET | Detail |
| Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal cancer and polyps amo... | DisGeNET | Detail |
| Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-κB signalings in c... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression of human papillomavirus is correlated with Ki-67 and COX-2 expressions in keratocystic od... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Importantly, ectopically expressed COX-2 or exogenous PGE2 were able to rescue migration defect in S... | DisGeNET | Detail |
| SSD treatment inhibited STAT3 activation [phosphorylation of STAT3 (p‑STAT3)], reduced the protein l... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Downregulation of fibronectin, Slug, and cyclooxygenase-2 (COX-2) expression and upregulation of E-c... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| COX-2 overexpression in resected pancreatic head adenocarcinomas correlates with favourable prognosi... | DisGeNET | Detail |
| We examined the association between COX-2 and DCAMKL1 expression in gastric carcinomas in clinical s... | DisGeNET | Detail |
| PTGS2 mRNA levels were higher in mild/moderate adenoma tissue compared to morphologically normal tis... | DisGeNET | Detail |
| Loss of IHH from Apc(HET) mice changed the composition of the adenoma stroma; cells that expressed α... | DisGeNET | Detail |
| Serum adiponectin concentrations, and the mRNA and protein expression of adiponectin and AdipoRs wer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ b... | DisGeNET | Detail |
| This study shows that 24-hydroxycholesterol, 27-hydroxycholesterol, and 7β-hydroxycholesterol, the t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Taken together, our results reveal a previously unrecognized non-cell-autonomous mechanism in TDP-43... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Polymorphisms in cyclooxygenase-2 gene and risk of developing coal workers' pneumoconiosis: a case-c... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Paederia foetida Linn. inhibits adjuvant induced arthritis by suppression of PGE(2) and COX-2 expres... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cyclooxygenase-2 (COX-2) is an inducible enzyme that catalyzes prostaglandins through inflammatory r... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The poor metabolic potential of HeLa, mainly concerning FADS2 upstream of COX-2 function, calls into... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These results suggest that miR‑101 may provide a novel mechanism for understanding cisplatin resista... | DisGeNET | Detail |
| ART efficiently inhibited orthotopic tumor growth in the bladder cancer rat, which is accompanied wi... | DisGeNET | Detail |
| In bladder cancer cell lines, cyclosporine A (CsA) and tacrolimus (FK506), immunosuppressant drugs/n... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In IL-32-induced macrophages, the production of IL-1β, IL-6, IL-8, and TNF-α, and expression of indu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our study confirmed that individuals who carried the polymorphisms that could affect the expressions... | DisGeNET | Detail |
| Induction of COX-2 expression required live bacteria and was not due to colibactin production, as si... | DisGeNET | Detail |
| Furthermore, cycling hypoxia-specific inflammatory phenotype, characterized by a simultaneous (bacul... | DisGeNET | Detail |
| Experimental data showed upregulation of the selected EGFR cascade in tumor cells, stromal expressio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Similarly, miR-17-92 levels are significantly elevated in NSCLC cells ectopically expressing COX-2. | DisGeNET | Detail |
| COX-2 overexpression and -8473 T/C polymorphism in 3' UTR in non-small cell lung cancer. | DisGeNET | Detail |
| Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features. | DisGeNET | Detail |
| Hu-antigen receptor (HuR) and cyclooxygenase-2 (COX-2) expression in human non-small-cell lung carci... | DisGeNET | Detail |
| Cyclooxygenase-2 genetic variants influence intratumoral infiltration of Foxp3-positive regulatory T... | DisGeNET | Detail |
| Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evalu... | DisGeNET | Detail |
| USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung can... | DisGeNET | Detail |
| The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inop... | DisGeNET | Detail |
| The current study investigated EGFR and COX-2 inhibition in patients with non-small cell lung cancer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs1801200 dbSNP
- Genome
- hg38
- Position
- chr1:186,671,791-186,680,922
- Variant Type
- snv
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