Annotation Detail
Information
- Associated Genes
- PTGS2
- Associated Variants
-
PTGS2 MUTATION
PTGS2 MUTATION - Associated Disease
- Malformations of Cortical Development, Group II
- Source Database
- DisGeNET
- Description
- Importantly, ectopically expressed COX-2 or exogenous PGE2 were able to rescue migration defect in STIM1 knockdown CRC cells, and inhibition of COX-2 with ibuprofen and indomethacin abrogated STIM1-mediated CRC cell motility.
- Pubmed
- 25381814
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs