Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
Associated Disease
Tumor Progression
Source Database
DisGeNET
Description
Cholangiocarcinogenesis and tumor progression are regulated by a novel interplay between COX-2/PGE2 and miR-21 signaling, which converges at 15-PGDH.
Pubmed
24699315
Section of the abstract supporting the evidence
IMPLICATIONS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0198152566618621
Drugs