actinic keratosis
Information
- Disease name
- actinic keratosis
- Disease ID
- DOID:8866
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02799082 | Completed | Phase 3 | Evaluation of Efficacy and Safety of BF-200 ALA Used With Photodynamic Therapy in Patients With Actinic Keratosis. | December 2007 | October 2008 |
| NCT00107965 | Completed | Phase 2 | Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic Keratoses | March 2005 | September 2005 |
| NCT00110682 | Completed | Phase 4 | Study of Imiquimod 5% Cream in Addition to Cryotherapy in the Management of Actinic Keratoses | April 2005 | December 2006 |
| NCT00189267 | Completed | Phase 2 | A Study to Evaluate the Effectiveness and Safety of Multiple Applications of Imiquimod 5% Cream for the Treatment of Actinic Keratoses in Organ Transplant Recipients | November 2002 | September 2005 |
| NCT00269074 | Completed | Phase 2 | Effect of IDEA-070 on Pain and Inflammation Induced by PDT | January 2006 | July 2006 |
| NCT00294320 | Completed | Phase 3 | Evaluation of Two Different Non-invasive Techniques to Monitor the Clearance of Actinic Keratosis Lesions | February 2006 | January 2007 |
| NCT00304239 | Completed | Phase 3 | Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp | March 13, 2006 | January 23, 2007 |
| NCT00306800 | Completed | Phase 3 | Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp | September 2007 | October 2007 |
| NCT00308854 | Completed | Phase 3 | Photodynamic Therapy With PD P 506 A Compared With Placebo-PDT for the Treatment of AK | March 2006 | December 2007 |
| NCT00308867 | Completed | Phase 3 | PD P 506 A-PDT Versus Placebo-PDT and Cryosurgery for the Treatment of AK | March 2006 | November 2007 |
| NCT00335179 | Completed | Phase 2 | Cellular and Molecular Events During Treatment of Actinic Keratosis With Imiquimod 5% Cream | January 2003 | July 2003 |
| NCT00375739 | Completed | Phase 2 | Study to Determine the Safety of PEP005 0.025% and 0.05% Topical Gel in Patients With Actinic Keratoses | September 2006 | June 2007 |
| NCT00472459 | Completed | Phase 3 | PDT With Metvix® 160 mg/g Cream in Organ Transplant Recipients With Non-melanoma Skin Cancer | July 2003 | July 2006 |
| NCT00544297 | Completed | Phase 2 | A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand | October 2007 | January 2008 |
| NCT00603798 | Completed | Phase 3 | Safety and Effectiveness Study of Imiquimod Creams for the Treatment of Actinic Keratoses (AKs) | January 2008 | July 2008 |
| NCT00659893 | Completed | Phase 1 | Safety and Toleration of PEP005 Topical Gel When Applied to a Treatment Area of up to 100cm2 | April 2008 | November 2008 |
| NCT00695578 | Completed | Phase 4 | Clinical Trial to Evaluate Biafine Cream Versus Standard Care in Subjects With Actinic Keratosis Post Cryotherapy | October 2006 | February 2008 |
| NCT00696488 | Completed | Phase 4 | Measuring Adherence To Topical 5-Fluorouracil in a Clinic Population | April 2007 | October 2008 |
| NCT00700063 | Completed | Phase 2 | A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp) | June 2008 | October 2008 |
| NCT00710489 | Completed | Potential Research Study Participant Registry | May 2008 | September 5, 2018 | |
| NCT00777127 | Completed | Phase 4 | Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses | December 2008 | November 2012 |
| NCT02938715 | Completed | N/A | Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil | October 2016 | September 2017 |
| NCT02952898 | Completed | Phase 3 | Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses | October 27, 2016 | September 6, 2017 |
| NCT02984072 | Completed | Phase 4 | Menthol for PDT Pain Relief | October 23, 2018 | October 10, 2019 |
| NCT02990221 | Completed | Phase 4 | Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy | April 12, 2017 | July 30, 2018 |
| NCT03006185 | Completed | Phase 2 | Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin | August 2016 | March 1, 2017 |
| NCT03037541 | Completed | Phase 3 | Cryosurgery and Cream Combination for Actinic Keratosis | January 5, 2011 | October 29, 2013 |
| NCT03083470 | Completed | Phase 2 | Study of SOR007 Ointment for Actinic Keratosis | May 18, 2017 | March 12, 2018 |
| NCT03110159 | Completed | Phase 1/Phase 2 | DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients | August 29, 2017 | February 20, 2024 |
| NCT03122457 | Completed | Phase 2 | Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide | January 1, 2017 | July 19, 2018 |
| NCT03200912 | Completed | Phase 3 | An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis | August 19, 2016 | March 22, 2017 |
| NCT03210740 | Completed | Phase 2 | Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis | June 6, 2017 | April 24, 2018 |
| NCT03285490 | Completed | Phase 3 | A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on Actinic Keratosis on Face or Scalp (AK004) | September 15, 2017 | April 24, 2019 |
| NCT03319251 | Completed | Biomarker Database Registry for Photodynamic Therapy | October 6, 2017 | October 31, 2023 | |
| NCT03327831 | Completed | Phase 4 | Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses | April 2015 | July 2017 |
| NCT03508856 | Completed | N/A | Clinical and Histologic Evaluation of Picato 0.15% Gel in the Cosmetic Improvement of Photoaged Skin | November 9, 2015 | August 9, 2016 |
| NCT03538951 | Completed | Phase 2 | Study to Evaluate the Efficacy, Safety, and Tolerability of Topical VDA-1102 Ointment in Subjects With Actinic Keratosis | May 23, 2018 | December 10, 2018 |
| NCT03643744 | Completed | Phase 1 | Photodynamic Therapy-Induced Immune Modulation: Part III | April 1, 2019 | March 21, 2023 |
| NCT03731988 | Completed | Phase 4 | Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis | February 1, 2017 | October 24, 2018 |
| NCT03805737 | Completed | N/A | Indoor Daylight Photo Dynamic Therapy for Actinic Keratosis | November 1, 2019 | October 6, 2021 |
| NCT03914417 | Completed | Phase 2 | Genomic Markers Before and After Treatment of Actinic Keratosis With Imiquimod 3.75% Cream | January 2013 | April 30, 2015 |
| NCT04140292 | Completed | Phase 2 | Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses | January 13, 2020 | May 27, 2021 |
| NCT04202445 | Completed | TreatMent of ActInic KerAtosis Lesions : pharmacoepiDemiological Study of the Impact in Real Life of ingenOl Mebutate Gel (Picato®) on Patients Satisfaction | April 2014 | February 2016 | |
| NCT04552327 | Completed | Phase 3 | 5% KOH Solution vs. Placebo and Diclofenac Gel for the Treatment of Actinic Keratosis | October 14, 2020 | January 24, 2023 |
| NCT05060237 | Completed | Phase 1 | Study to Evaluate Safety and Tolerability of BF-200 ALA (Ameluz®) for Photodynamic Therapy in the Treatment of the Expanded Field of Actinic Keratosis on Face and Scalp | December 1, 2021 | April 20, 2023 |
| NCT05231044 | Completed | Phase 3 | A Multi-Center Study to Evaluate the Efficacy and Safety of KX01 Ointment 1% on Actinic Keratosis on Face or Scalp | December 21, 2021 | November 20, 2023 |
| NCT05741294 | Completed | Phase 4 | A Study of Tirbanibulin on the Wellbeing of Participants With Actinic Keratoses | January 17, 2023 | December 21, 2023 |
| NCT05900258 | Completed | Phase 4 | Tirbanibulin 1% Ointment for the Treatment of Chronically Sun-damaged Skin on the Face | May 11, 2023 | November 13, 2023 |
| NCT00828568 | Completed | Phase 1 | Bioequivalence Study of Two Imiquimod Cream 5% | June 2008 | May 2009 |
| NCT00843323 | Completed | N/A | Photodynamic Therapy (PDT) Effect on Large Surface Photodamaged Skin | December 2008 | June 2009 |
| NCT00850681 | Completed | Phase 1 | A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers | February 2009 | April 2009 |
| NCT00850811 | Completed | Phase 1 | A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers | February 2009 | April 2009 |
| NCT00852137 | Completed | Phase 2 | A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic Keratosis | March 2009 | June 2009 |
| NCT00859105 | Completed | Phase 3 | A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled Therapeutic Equivalence Study of Three Imiquimod Cream 5% Treatments for Patients With Actinic Keratosis | February 2008 | |
| NCT00894647 | Completed | Phase 3 | Safety and Effectiveness Study of Actinic Keratosis Treatment Following Cryosurgery | May 2009 | February 2010 |
| NCT00915551 | Completed | Phase 3 | A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) | June 2009 | September 2009 |
| NCT00916006 | Completed | Phase 3 | A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) | June 2009 | September 2009 |
| NCT00917306 | Completed | Phase 3 | A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities) | June 2009 | September 2009 |
| NCT00926952 | Completed | Phase 3 | Short Incubation Methylaminolevulinate Photodynamic Therapy Without Occlusion | July 2009 | January 2011 |
| NCT00952783 | Completed | A Long Term Follow up Study of Patients Who Have Completed the PEP005-020 Study | July 2009 | October 2010 | |
| NCT00953732 | Completed | A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies | August 2009 | October 2010 | |
| NCT00987246 | Completed | Phase 3 | Study on the Efficacy of LAS41005 in the Treatment of Actinic Keratosis | June 2008 | June 2009 |
| NCT00989313 | Completed | A Long Term Follow up Study of Patients Who Have Complete Clearance of Their Actinic Keratosis (AK) Lesions at the Day 57 Visit in the PEP005-028 Study | September 2009 | October 2010 | |
| NCT00991861 | Completed | Phase 2 | Efficacy and Safety Study of LAS41007 in the Treatment of Actinic Keratosis | August 2009 | February 2010 |
| NCT01000636 | Completed | Phase 4 | Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT) | October 2009 | October 2011 |
| NCT01151956 | Completed | Imiquimod and Actinic Keratoses: an Observational Study | May 2008 | May 2009 | |
| NCT01260987 | Completed | Phase 2/Phase 3 | Fractional CO2 Laser Assisted Photodynamic Therapy | October 2010 | August 2012 |
| NCT01265602 | Completed | Phase 3 | Double-blind, Randomized, Vehicle- and Comparator-controlled, Multi-center Trial to Evaluate the Efficacy and Safety of LAS41007 in the Treatment of Actinic Keratosis | November 2010 | March 2012 |
| NCT01302925 | Completed | Phase 1 | PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy Subjects | February 2011 | March 2011 |
| NCT01358851 | Completed | Phase 2 | LAS41005 in Hyperkeratotic Actinic Keratosis | April 2011 | August 2012 |
| NCT01387711 | Completed | Phase 1 | PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology | August 2011 | June 2012 |
| NCT01444989 | Completed | N/A | Development and Validation of a Quality of Life Instrument for Actinic Keratosis | September 2011 | March 2012 |
| NCT01449513 | Completed | Phase 1 | PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy | September 2011 | May 2012 |
| NCT01453179 | Completed | Phase 4 | Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2) | October 2011 | March 2015 |
| NCT01459393 | Completed | Phase 3 | Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment | November 2010 | November 2011 |
| NCT01475955 | Completed | Phase 2 | Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK) | December 2011 | November 2012 |
| NCT01493921 | Completed | Phase 3 | Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment | October 2011 | November 2015 |
| NCT01516515 | Completed | Phase 2 | Efficacy and Safety Phase II Study of SR-T100 to Treat Actinic Keratosis | February 2013 | October 2018 |
| NCT01541228 | Completed | N/A | Photodynamic Treatment of Actinic Keratoses With Different Light Doses | April 2010 | April 2013 |
| NCT01541553 | Completed | Phase 3 | A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp | March 2012 | July 2013 |
| NCT01571336 | Completed | Photodynamic Therapy of Actinic Keratoses With Alacare® | April 2012 | September 2016 | |
| NCT01583816 | Completed | Phase 2 | Dose-finding, Safety, Efficacy Trial of Topical Resiquimod in Patients With Multiple Actinic Keratosis Lesions | May 2012 | June 2014 |
| NCT01600014 | Completed | Phase 3 | Ingenol Mebutate Gel, 0.015% Repeat Use for Multiple Actinic Keratoses on Face and Scalp | May 2012 | February 2014 |
| NCT01611480 | Completed | Phase 2 | Efficacy and Safety of a New Topical Formulation With Imiquimod (Limtop) Applied 1, 3 or 7 Times Weekly During 2 x 2 Weeks Treatment for Actinic Keratosis on the Head | ||
| NCT01686152 | Completed | Phase 3 | Study Comparing Imiquimod Cream, 3.75% to Zyclara® (Imiquimod) Cream, 3.75% in the Treatment of Actinic Keratosis | September 2012 | August 2013 |
| NCT01703078 | Completed | Phase 1 | Safety and Tolerability of Different Concentrations of an Ingenol Derivative Field Therapy in the Treatment of Actinic Keratosis | November 2012 | April 2013 |
| NCT01742663 | Completed | Phase 1 | A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® Gel 3% in the Treatment of Actinic Keratosis | October 2012 | October 2013 |
| NCT01787383 | Completed | Phase 3 | A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/Extremities | February 2013 | January 2014 |
| NCT01788007 | Completed | Phase 1 | Clinical Study to Evaluate the Bioequivalence of Two Imiquimod Cream 3.75% Formulations in Patients With Actinic Keratosis. | January 2013 | December 2013 |
| NCT01803477 | Completed | Phase 1/Phase 2 | Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the Forearm | February 2013 | December 2013 |
| NCT01812837 | Completed | N/A | The Use of Microneedles in Photodynamic Therapy | July 2012 | March 2014 |
| NCT01820260 | Completed | Phase 1/Phase 2 | Safety and Efficacy of Ingenol Mebutate Once Daily for 2 or 3 Consecutive Days in Subjects With Actinic Keratosis | April 2013 | August 2014 |
| NCT01836367 | Completed | Phase 1 | Ingenol Mebutate 0.015% Gel in the Treatment of Actinic Keratoses (AK) on the Face and Scalp | March 2013 | August 2013 |
| NCT01892137 | Completed | Phase 1 | Histological Confirmation of Clinical Clearance of Actinic Keratoses Following Treatment With Ingenol Mebutate Gel, 0.05% | July 2013 | May 2014 |
| NCT01898936 | Completed | N/A | Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic for Treatment of Actinic Keratoses | August 2013 | December 2016 |
| NCT01905891 | Completed | N/A | Nanocytology Test to Evaluate Skin Cancer in High Risk Patients | July 2013 | November 2014 |
| NCT01922050 | Completed | Phase 1/Phase 2 | A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis | October 2013 | November 2014 |
| NCT01962987 | Completed | Phase 3 | A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® (Diclofenac Sodium) Gel 3% in the Treatment of Actinic Keratosis | March 2013 | September 2013 |
| NCT01966120 | Completed | Phase 3 | Safety and Efficacy Study for the Field-directed Treatment of Actinic Keratosis (AK) With Photodynamic Therapy (PDT) | October 2013 | April 2015 |
| NCT01998984 | Completed | Phase 2 | Efficacy and Safety of Ingenol Mebutate Gel 0.06% When Applied Once Daily for 2, 3 or 4 Consecutive Days to a Treatment Area of Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis | January 2014 | July 2014 |
| NCT02019355 | Completed | Early Phase 1 | Actinic Keratosis Study | October 2013 | March 2015 |
| NCT02029066 | Completed | Phase 1 | Pharmacokinetic Study of Solamargine in Patients With Actinic Keratosis | November 2013 | February 2014 |
| NCT02085395 | Completed | Phase 2 | Clinical Study Assessment of SR-T100 Topical Gel Against Actinic Keratosis | November 2007 | November 2010 |
| NCT02090465 | Completed | Assessment of Treatment Success and Quality of Life in Patients With Actinic Keratoses Under Therapy With Ingenol Mebutate in a Period of 8 Weeks | July 2013 | December 2013 | |
| NCT02100813 | Completed | Phase 1/Phase 2 | Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis | May 2014 | March 2015 |
| NCT02120456 | Completed | Phase 1/Phase 2 | Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis | May 2014 | May 2015 |
| NCT02120898 | Completed | Phase 3 | A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses | October 10, 2013 | April 30, 2014 |
| NCT02124239 | Completed | Phase 1 | Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions | April 2014 | November 2014 |
| NCT02124733 | Completed | Phase 3 | Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses | April 2014 | December 2018 |
| NCT02126670 | Completed | Phase 2 | ACT01 in Combination With Comp01-04 in Patients With Actinic Keratosis | April 2014 | September 2014 |
| NCT02137785 | Completed | Phase 3 | Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities | May 2014 | March 2015 |
| NCT02209012 | Completed | Twelve Month Follow-Up of CP0108 | August 2014 | April 2016 | |
| NCT02239679 | Completed | Phase 2 | Controlled Study of the Occurrence of Actinic Keratosis on the Face After Cryotherapy + Aminolevulinic Acid (ALA) Photodynamic Therapy | September 2014 | September 2016 |
| NCT02242747 | Completed | N/A | Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis | May 2014 | August 2014 |
| NCT02248298 | Completed | Phase 1 | Efficacy of AFL-assisted PDT With Short Incubation Time in Actinic Keratosis | January 2012 | June 2014 |
| NCT02278861 | Completed | Phase 2 | Oral Isotretinoin Versus Topical Tretinoin for Actinic Keratosis | November 2011 | May 2014 |
| NCT02289768 | Completed | Phase 3 | Study To Evaluate The Efficacy And Safety Of Actikerall® Solution In Patients With Grade I-II Actinic Keratoses | October 2014 | September 2015 |
| NCT02305888 | Completed | Phase 2 | Safety of LEO 43204 for Actinic Keratosis Applied on Face/Chest, Scalp and Trunk/Extremities, Respectively | March 2015 | August 2015 |
| NCT02325661 | Completed | N/A | Open Uncontrolled Validation Study for the German Version of the Actinic Keratosis Quality of Life Questionnaire (AKQoL) | October 2014 | December 2014 |
| NCT02337205 | Completed | Phase 1 | Ph 1, Single-Center, Safety, Tolerability & Pharmacokinetic Study of KX2 391 Ointment in Subj. w Actinic Keratosis | December 2014 | March 2016 |
| NCT02361216 | Completed | Phase 3 | Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or Chest | April 2015 | March 2017 |
| NCT02362152 | Completed | The Real Life Topical Field Treatment of Actinic Keratosis Study | July 2014 | December 2015 | |
| NCT02385318 | Completed | Phase 3 | To Compare Safety and Efficacy of Perrigo's Drug Product Compared to an FDA Approved Drug Product in the Treatment of Actinic Keratosis | February 2015 | December 2015 |
| NCT02404389 | Completed | Phase 2 | Safety, Tolerability, and Efficacy Study of LFX453 in Actinic Keratosis Patients | March 5, 2015 | January 27, 2016 |
| NCT02421471 | Completed | PMS to Evaluate the Safety and Efficacy of Picato® Gel | September 2014 | January 19, 2018 | |
| NCT02424305 | Completed | Phase 1 | Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use Conditions | May 2015 | July 2015 |
| NCT02446223 | Completed | Phase 4 | Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015% | January 2015 | September 2016 |
| NCT02459795 | Completed | Phase 3 | To Compare Safety and Efficacy of Perrigo's Drug Compared to an FDA Approved Drug in the Treatment of Actinic Keratosis | May 2015 | December 2015 |
| NCT02464709 | Completed | Phase 4 | Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL) | June 2015 | October 2017 |
| NCT02547233 | Completed | Phase 3 | Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up | November 2015 | November 2017 |
| NCT02547363 | Completed | Phase 3 | Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up | November 2015 | August 2017 |
| NCT02549339 | Completed | Phase 3 | Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up | November 13, 2015 | August 10, 2017 |
| NCT02549352 | Completed | Phase 3 | Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up | November 2015 | August 2017 |
| NCT02559934 | Completed | Phase 1 | Multiple-dose Pharmacokinetic Study of Solamargine in Patients With Actinic Keratosis | November 2015 | May 2019 |
| NCT02594436 | Completed | The Use of Picato® (Ingenol Mebutate) to Treat Actinic Keratosis in Standard Clinical Practice | December 1, 2015 | November 2017 | |
| NCT02600598 | Completed | Phase 1 | Biological Effects of LEO 43204 in Actinic Keratosis | July 2016 | January 16, 2017 |
| NCT02611804 | Completed | Phase 3 | A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled, Multicenter Study Comparing Diclofenac Sodium Gel, 3% to Solaraze® Gel, 3% in the Treatment of Actinic Keratosis on the Face or Bald Scalp | October 2015 | August 2016 |
| NCT02616601 | Completed | Phase 3 | Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis | February 27, 2015 | September 17, 2015 |
| NCT02632110 | Completed | Phase 2 | Microneedle Lesion Preparation Prior to Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) for AK on Face | March 2016 | September 12, 2016 |
| NCT02650505 | Completed | Phase 1 | A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 Gel | February 2016 | June 2016 |
| NCT02654717 | Completed | Phase 2 | Eight Week Study of Treatment With DFD-07 for Actinic Keratosis of the Face and Scalp | November 2015 | August 2016 |
| NCT02654769 | Completed | Phase 3 | A Study of Equivalence of Generic Ingenol Mebutate Gel 0.05% and Picato Gel 0.05% in Subjects With Actinic Keratosis | February 2015 | September 2015 |
| NCT02670655 | Completed | Phase 1 | Efficacy of Iontophoresis-assisted AFL-PDT in Actinic Keratosis | June 2014 | December 2015 |
| NCT02674048 | Completed | Metvix Daylight PDT in Actinic Keratosis | September 2015 | November 2016 | |
| NCT02716714 | Completed | Phase 4 | Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis | April 2015 | June 2016 |
| NCT02799030 | Completed | Phase 2 | A Clinical Trial of Topical Photodynamic Therapy With 5-aminolevulinic Acid for the Treatment of Actinic Keratosis | October 2006 | March 2007 |
| NCT02799069 | Completed | Phase 3 | Evaluation of Safety and Efficacy of BF-200 ALA for the Treatment of Actinic Keratosis With Photodynamic Therapy | April 2008 | August 2009 |
| NCT00089180 | Completed | Phase 2 | T4N5 Liposomal Lotion in Preventing The Recurrence of Nonmelanoma Skin Cancer in Patients Who Have Undergone a Kidney Transplant | March 2004 | |
| NCT02838628 | Completed | Phase 2 | Activity & Safety Study of KX2-391 Ointment in Participants With Actinic Keratosis on the Face or Scalp | April 11, 2016 | December 22, 2017 |
| NCT02844777 | Completed | Phase 2 | Efficacy and Safety of VDA-1102 Ointment in the Treatment of Actinic Keratosis | July 15, 2016 | May 26, 2017 |
| NCT02866695 | Completed | Phase 4 | Safety and Efficacy of Ingenol Mebutate Gel 0.015% for Treatment of AK on the Face in Solid Organ Transplant Recipients | October 6, 2016 | July 2, 2018 |
| NCT02878382 | Completed | N/A | Potential Impact of Patient Vitamin D Status in AK Response to MAL-PDT | October 2016 | April 2020 |
| NCT02902822 | Completed | N/A | Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo | October 2016 | May 2019 |
| NCT02759900 | Recruiting | N/A | Using a Cold Atmospheric Plasma Device to Treat Skin Disorders | January 2016 | January 2025 |
| NCT06319794 | Recruiting | Phase 2 | Study on the Safety and Efficacy of Bimiralisib Gel in Participants Suffering From Actinic Keratosis | April 2, 2024 | December 2024 |
| NCT05699603 | Recruiting | Phase 2 | Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients | August 18, 2024 | February 1, 2029 |
| NCT05688904 | Recruiting | Phase 1 | The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy | January 19, 2023 | March 2028 |
| NCT06027619 | Recruiting | Phase 2 | Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses | October 2, 2023 | December 1, 2024 |
| NCT02150863 | Terminated | N/A | Treatment of Field Cancerization for Reduction in Tumor Burden - A Prospective Study | August 2014 | April 2018 |
| NCT01806961 | Terminated | Observational Trial Tolerability and Efficacy of Resiquimod Gel in Patients Treated for Actinic Keratosis. | January 2013 | September 2013 | |
| NCT01525329 | Terminated | Phase 3 | Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease | September 2011 | December 2016 |
| NCT03115476 | Terminated | Phase 3 | A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or Scalp | June 16, 2017 | March 12, 2018 |
| NCT02473848 | Terminated | Phase 3 | Ingenol Mebutate Gel 0.05% in Kidney Transplant Recipients With Actinic Keratoses | June 2015 | December 2017 |
| NCT01203878 | Terminated | Phase 4 | Treatment of Actinic Keratoses of the Face With Imiquimod 3.75% Cream Followed by Photodynamic Therapy | September 2010 | November 2011 |
| NCT01405144 | Unknown status | Phase 3 | 5fluorouracil for Advanced Photoaging | August 2010 | March 2012 |
| NCT01413763 | Unknown status | Phase 4 | Potential Effect of Topical Imiquimod on Atrial Ectopy in Patients With Actinic Keratosis | July 2011 | April 2013 |
| NCT03013647 | Unknown status | N/A | Daylight Photodynamic Therapy for Actinic Keratosis and Skin Field Cancerization | September 2016 | July 2017 |
| NCT01481155 | Unknown status | N/A | Comparative Study of Photodynamic Therapy vs. CO2 Laser Therapy in Treatment of Actinic Keratoses | March 2011 | |
| NCT02647151 | Unknown status | Phase 4 | Efficacy and Safety of Treatment of Actinic Keratoses With Photodynamic Therapy Between MAL Cream and ALA Gel | December 2015 | March 2016 |
| NCT04396184 | Unknown status | N/A | Conventional Photodynamic Therapy vs. Painless Photodynamic Therapy for Actinic Keratosis | May 1, 2020 | April 30, 2021 |
| NCT03684772 | Unknown status | Phase 2 | Topical Ionic Contra-Viral Therapy in Actinic Keratosis | October 22, 2018 | September 2019 |
| NCT01656226 | Unknown status | Phase 4 | Long Term Efficacy and Safety of Eryfotona AK-NMSC® in Patients With Actinic Keratosis | July 2012 | January 2014 |
| NCT04779255 | Unknown status | N/A | Pain Management During a Photodynamic Therapy Session on the Vertex for Actinic Keratosis: Tumescent Anesthesia Interest | July 28, 2021 | November 2022 |
| NCT01229319 | Unknown status | Phase 4 | Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses | October 2010 | August 2011 |
| NCT02354391 | Unknown status | Phase 2 | Ingenol Mebutate (Picato®) With Methyl Aminolevulinate Photodynamic Therapy for the Treatment of Actinic Keratosis | January 2015 | December 2019 |
| NCT05152407 | Unknown status | N/A | MRB 0.3% Serum Effectiveness on 2 Early Clinical Markers of Photoinduced Cutaneous Aging: Actinic Lentigo and Actinic Keratosis | January 2022 | July 2023 |
| NCT03024060 | Withdrawn | Phase 3 | Phase 3 Study of Levulan With New Blue Light for AK on the Face or Scalp | March 2017 | January 2018 |
| NCT00814528 | Withdrawn | N/A | Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses | November 2007 | September 2009 |
| NCT02867722 | Withdrawn | N/A | Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States | December 2020 | December 2022 |
| NCT01735942 | Withdrawn | Early Phase 1 | Ingenol Mebutate Compared to Cryotherapy for the Treatment of Skin Lesions | October 2012 | May 2016 |
- Disase is a (Disease Ontology)
- DOID:0060071
- Cross Reference ID (Disease Ontology)
- ICD10CM:L57.0
- Cross Reference ID (Disease Ontology)
- ICD9CM:702.0
- Cross Reference ID (Disease Ontology)
- ICDO:8070/0
- Cross Reference ID (Disease Ontology)
- MESH:D055623
- Cross Reference ID (Disease Ontology)
- NCI:C3148
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:267858008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0022602
- Exact Synonym (Disease Ontology)
- actinic (Solar) Keratosis
- Exact Synonym (Disease Ontology)
- Senile hyperkeratosis
- Exact Synonym (Disease Ontology)
- SK - Solar keratosis
- Exact Synonym (Disease Ontology)
- Solar keratosis
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0025127
- ICD10 preferred id (Insert disease from ICD10)
- D0009829
- ICD10 class code (Insert disease from ICD10)
- L57.0