Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
Associated Disease
Breast Cancer Model
Source Database
DisGeNET
Description
Our previously published work in a preclinical breast cancer model showed that integrin α3β1 promotes expression of cyclooxygenase-2 (COX2/PTGS2), a known driver of breast cancer progression.
Pubmed
24950714
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs