Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
Associated Disease
Bacterial Infections
Source Database
DisGeNET
Description
The poor metabolic potential of HeLa, mainly concerning FADS2 upstream of COX-2 function, calls into question whether these cells represent a good model to unveil fatty acid or downstream eicosanoid effects in the course of intracellular bacterial infection.
Pubmed
25549244
Section of the abstract supporting the evidence
CONCLUSIONS/SIGNIFICANCE
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
14
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00353867585870808
Drugs