Gastrointestinal Neoplasms

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Information
Disease name
Gastrointestinal Neoplasms
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04592913 Active, not recruiting Phase 3 Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer November 17, 2020 September 27, 2027
NCT02795988 Active, not recruiting Phase 1/Phase 2 A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer August 30, 2017 August 2024
NCT06260150 Active, not recruiting N/A Application of IPC During Surgery to Prevent Venous Thrombosis in Gastrointestinal Surgery Patients. April 1, 2023 April 2024
NCT04919824 Active, not recruiting N/A Monopolar Current Cutting Knife vs Bipolar RFA Knife January 25, 2022 December 30, 2024
NCT01946854 Active, not recruiting N/A Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei July 16, 2013 July 31, 2025
NCT05551052 Active, not recruiting CRC Detection Reliable Assessment With Blood September 8, 2022 July 2024
NCT00289445 Completed Phase 1/Phase 2 Study With Mitomycin c/5-FU/FA in Pretreated Gastrointestinal Cancer Patients With Metastases (>= Second-line Treatment) September 1999 March 2006
NCT00390182 Completed Phase 1/Phase 2 Low Dose Upper Abdominal Radiation Therapy (LD-UART) + Gemcitabine in Patients With Advanced, Unresectable Pancreatic Cancer (PC) October 2003 May 2011
NCT00422409 Completed N/A Endoscopic Stenting of Gastrointestinal Cancer October 2006 April 2010
NCT00436657 Completed Phase 1 Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer February 2007 April 2011
NCT00570635 Completed Phase 2 A Phase 2 Study of XL820 in Adults With Advanced GIST Resistant to Imatinib and/or Sunitinib December 2007 May 2009
NCT00990535 Completed Phase 2 High Dose Somatostatin Analogues in Neuroendocrine Tumors January 2006 December 2008
NCT01291407 Completed Phase 1 A Phase I Study of S-1 in Combination With Radiotherapy in Locally Advanced or Recurrent Gastric Cancer November 2010 September 2013
NCT01415609 Completed Endoscopic Submucosal Dissection Registry August 2010 March 2012
NCT01567488 Completed Phase 2 Phase II Study of Everolimus Combined With Octreotide LAR to Treat Advanced GI NET June 8, 2011 June 7, 2017
NCT04694521 Completed N/A Outcomes of Side-to-end Versus End-to-end Colorectal Anastomosis in Non-emergent Sigmoid and Rectal Cancers: Randomized Controlled Clinical Trial September 2016 September 2020
NCT00041808 Completed Phase 1/Phase 2 Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver July 2001 April 2003
NCT00120939 Completed Phase 1 Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer
NCT00190801 Completed Phase 2 Phase 2 Study on Use of a Combination of Pemetrexed in Patients With Advanced Gastric Carcinoma September 2003 September 2005
NCT00196885 Completed Phase 2 Effect of an Antioxidant on Cancer-Cachectic Patients Undergoing Exercise Training December 2003 December 2006
NCT00247338 Completed Phase 4 The Impact of Low Calorie and Low Nitrogen Parenteral Nutrition Support on the Clinical Outcome of Postoperative Patients April 2005 May 2006
NCT01693445 Completed Phase 1 S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal Cancer June 2012 August 2014
NCT01816607 Completed Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness October 2013 December 2017
NCT01982994 Completed N/A Intervention to Motivate Standing &Walking in Gastrointestinal Cancer Surgical Patients October 2013 December 2018
NCT01996306 Completed Phase 3 A Phase III Study of 2nd-line XELIRI ± Bevacizumab vs. FOLFIRI ± Bevacizumab in mCRC December 2, 2013 June 30, 2018
NCT02444572 Completed Phase 4 Comparison of Thromboembolic Events in Patients Undergoing Thromboprophylactic Treatment With ENOXA® vs Lovenox® October 2015 July 10, 2020
NCT02454647 Completed Induction Chemotherapy, Chemoradiotherapy and Surgery in Locally Advanced Gastric Cancer Patients September 2013 March 2015
NCT02485561 Completed N/A Evaluating Strategies to Present Colon Cancer Screening Information June 1, 2015 January 31, 2017
NCT02486094 Completed Study of PRoliferation and Apoptosis in Rectal Cancer, Predictive & Prognostic biOmarkers: Histopathology and Imaging June 2015 June 7, 2017
NCT02507414 Completed N/A Mesenteric Traction Syndrome During Upper Gastrointestinal Surgery August 2014 September 2016
NCT02951273 Completed Cerebral Blood Flow During Propofol Anaesthesia December 8, 2016 July 6, 2017
NCT03037385 Completed Phase 1/Phase 2 Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors March 17, 2017 March 21, 2024
NCT03309917 Completed N/A The Effect of Blood Pressure on Cerebral Blood Flow During Propofol Anesthesia December 27, 2017 April 19, 2018
NCT03549494 Completed Phase 2 Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction October 25, 2018 February 15, 2023
NCT03559543 Completed Phase 2 Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal Adenocarcinoma October 25, 2018 January 15, 2024
NCT03674294 Completed Phase 3 Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy August 4, 2015 June 1, 2020
NCT04010227 Completed N/A Telephone Support for Advanced Gastrointestinal Cancer Patients and Caregivers September 16, 2019 June 8, 2021
NCT04080843 Completed Phase 2 Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type mCRC Patients November 15, 2019 July 1, 2022
NCT04137289 Completed Phase 1 A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal Cancer March 11, 2020 November 27, 2023
NCT04145297 Completed Phase 1 Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas March 17, 2020 August 18, 2022
NCT04361227 Completed Utility of OverStitch Sx After ESD July 2, 2020 October 20, 2022
NCT04670718 Completed N/A The Use of a OCT Probe in Assessment of Endoscopic and Surgical Resection Specimen of Gastrointestinal Tract December 10, 2020 June 30, 2021
NCT04673136 Completed N/A Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program. April 1, 2021 March 31, 2022
NCT00001431 Completed Phase 1 A Phase I Trial of Gemcitabine and Radiation in Locally Advanced Unresectable Cancer of the Pancreas February 1995 November 2000
NCT04752670 Completed ConMed Beamer Study May 27, 2021 May 1, 2022
NCT05012527 Completed Retrospective Review of Gastrointestinal System Endoscopy Procedures June 11, 2021 October 1, 2021
NCT05113134 Completed N/A Transvaginal Versus Transabdominal Extraction of Laparoscopically-excised Specimen March 2, 2015 July 24, 2020
NCT05163665 Completed N/A Cost-effective Analysis of Two Approximation Devices in Closure of Gastrointestinal Defects August 23, 2022 September 11, 2023
NCT05178095 Completed N/A Artificial Intelligence in Colonic Polyp Detection September 30, 2020 June 1, 2023
NCT05190042 Completed N/A Clinical Study on Continuous Suture of Endoscopic Mucosal Defects January 18, 2022 July 30, 2022
NCT06048146 Enrolling by invitation N/A A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node Metastasis October 1, 2022 September 1, 2029
NCT05552729 Not yet recruiting Phase 1/Phase 2 Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors September 22, 2022 December 30, 2022
NCT05280210 Not yet recruiting N/A PTC in Personalizing Neoadjuvant Therapy for Patients With Advanced Gastrointestinal Tumor April 1, 2022 December 31, 2024
NCT04949282 Recruiting Spanish Series of Patients Treated With the Radionuclide Lutetium177 May 10, 2021 December 31, 2035
NCT04937647 Recruiting Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy June 16, 2021 June 15, 2023
NCT04907643 Recruiting N/A Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes October 5, 2021 March 2026
NCT05106244 Recruiting N/A Remote Real-Time Guidance System in Home Care of Patients With PICC or PORT January 1, 2022 August 30, 2024
NCT02196935 Recruiting Los Angeles Prospective GI Biliary and EUS Series September 2010 December 2025
NCT04755920 Recruiting Phase 2 SGM-101 in Colorectal Brain Metastases. January 1, 2024 February 2026
NCT05772546 Recruiting Phase 2 Avatrombopag vs. Placebo for CIT in GI Malignancies November 1, 2023 July 31, 2025
NCT01750619 Recruiting Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions July 2011 December 2024
NCT05159479 Recruiting Defining Robust Predictors of Chemotherapy Related Cardiotoxicity October 13, 2021 July 1, 2024
NCT05494060 Recruiting Phase 2 XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma March 16, 2022 February 2027
NCT04426669 Recruiting Phase 1/Phase 2 A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering May 15, 2020 January 2024
NCT05980416 Recruiting Phase 1 Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2 August 10, 2023 December 2028
NCT03597581 Recruiting Phase 1 A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer June 5, 2018 December 31, 2024
NCT03602677 Recruiting N/A Indocyanine Green Fluorescence Imaging in Prevention of Colorectal Anastomotic Leakage September 24, 2018 December 1, 2023
NCT06301828 Recruiting Phase 2 Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors February 21, 2024 February 21, 2026
NCT04393584 Recruiting Phase 2/Phase 3 FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma January 29, 2019 January 1, 2026
NCT04363983 Recruiting N/A Interaction Between Host, Microenvironment and Immunity on Gastrointestinal Neoplasms January 13, 2021 January 2031
NCT06365866 Recruiting N/A Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer. February 19, 2024 December 2024
NCT04084249 Recruiting N/A ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial January 1, 2020 June 30, 2028
NCT05252078 Recruiting Phase 2 Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients June 2, 2022 November 2026
NCT05160168 Terminated Phase 1/Phase 2 A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) January 3, 2022 February 2, 2024
NCT02820077 Terminated N/A Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions August 6, 2016 August 27, 2020
NCT02859064 Terminated Phase 2 Study of Lanreotide in Patients With Metastatic Gastrointestinal Neuroendocrine Tumors Who Are Undergoing Liver-directed Radioembolization With Yttrium-90 Microspheres July 28, 2017 June 10, 2022
NCT00300027 Terminated Phase 1 Study of BMS-582664 in Combination With Either FOLFIRI or FOLFOX for Gastrointestinal (GI) Malignancies April 2006
NCT04644315 Terminated Phase 2 A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors May 24, 2021 May 16, 2022
NCT01624090 Terminated Phase 2 Mithramycin for Lung, Esophagus, and Other Chest Cancers September 6, 2012 September 27, 2019
NCT01790035 Terminated Phase 1 Probiotic LGG for Prevention of Side Effects in Patients Undergoing Chemoradiation for Gastrointestinal Cancer August 19, 2014 December 12, 2021
NCT01853241 Terminated Prospective Randomized Trial of Anterograde Single Balloon Versus Spirus Enteroscopy May 2010 January 2011
NCT02080702 Terminated An International, Multicentric, Prospective, Observational Study to Evaluate Monosyn® Suture Material for Anastomoses in the Gastrointestinal Tract August 2014 June 2016
NCT02417753 Terminated Phase 2 AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites April 3, 2015 April 7, 2016
NCT00767234 Terminated Permission to Collect Blood Over Time for Research August 2008 October 2011
NCT02744651 Terminated N/A EUS-Endodrill vs. EUS-FNA for Diagnosis of Submucosal Tumors in the Upper GI Tract February 17, 2017 December 31, 2021
NCT00452205 Unknown status Bone Marrow-derived Cells' Contribution to Tumor Formation and Inflammation April 2007 March 2017
NCT03330964 Unknown status N/A Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin Neurotoxicity September 1, 2017 May 2018
NCT03303495 Unknown status Phase 3 A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC November 14, 2011 December 31, 2018
NCT02837679 Unknown status N/A Oncogeriatric Intervention and Follow-up at Home January 2016 January 2023
NCT03271255 Unknown status Phase 2 Apatinib Versus Bevacizumab in Second-line Therapy for Colorectal Cancer(ABST-C) May 23, 2018 December 31, 2022
NCT02512328 Unknown status Phase 1 Improvement of Colonoscopy Preparation by New Media (APP) March 2015 October 2015
NCT02866045 Unknown status Phase 3 EUS-FNB vs. Single-incision Needle-knife (SINK) Biopsy for Gastrointestinal SELs May 2016 December 2018
NCT03488446 Unknown status Radiomics for Prediction of Lymph Node Metastasis in Gastric Cancer(RPLNM)(GIPMCS-1701) August 30, 2017 March 31, 2019
NCT02860429 Unknown status Phase 4 Clinical Trial of Cinobufacini Injection Combined With Oxaliplatin Regimen on Gastrointestine Carcinoma September 2016
NCT03065257 Unknown status Endoscopic Resection Multicenter Registry March 15, 2017 April 2020
NCT01995942 Unknown status Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial June 7, 2013 February 2, 2022
NCT02005965 Unknown status Low Rectal Cancer Study (MERCURY II) August 13, 2007 March 11, 2021
NCT02513849 Unknown status Phase 1 Tamoxifen in Patients With Oesophageal Cancer December 2015 November 2018
NCT02169388 Unknown status Phase 1 Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy June 2014 January 2015
NCT03050333 Unknown status Efficacy and Safety of Endoscopic Resection April 25, 2013 December 31, 2023
NCT02215837 Unknown status Phase 2 Study of Autologous Tumor Lysate-pulsed D-CIK Combined With Chemotherapy for Gastric Cancer August 2014 May 2018
NCT02226224 Unknown status Endoscopic Ultrasound in Detailed T-staging of Upper GI Malignancies in Vitro June 2014 October 2020
NCT02233205 Unknown status Phase 1/Phase 2 Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Digestive System October 2014 June 2016
NCT02672774 Unknown status N/A Novel Endoscopic Imaging Methods for the Evaluation of Blood Vessels in Gastrointestinal Cancers October 2015 September 2017
NCT02871245 Unknown status N/A Clinical Trial on Acupuncture Therapy in Patients With Gastrointestinal Neoplasms Laparoscopic Surgery September 21, 2016 July 2017
NCT02450656 Unknown status Phase 1/Phase 2 Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer June 2015 December 2019
NCT02785523 Unknown status Phase 3 Clinical Trial on Ganoderma Spore Lipids Combined With Chemo in Patients With G.I. Cancers May 2016
NCT05322486 Unknown status Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases October 29, 2020 December 2022
NCT05232357 Unknown status Early Phase 1 Endoscopic Vital Nerve Staining in Gastrointestinal Diseases March 1, 2022 May 15, 2022
NCT03889626 Unknown status Phase 3 The Maintenance Treatment of Apatinib/Capecitabine Versus Observation in Advanced Gastric Cancer March 22, 2019 March 22, 2024
NCT01037049 Unknown status Phase 2 Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks October 16, 2009 December 8, 2019
NCT01422928 Withdrawn Phase 3 Acupuncture for the Immune System in Radiation Cancer Patients December 2010 December 2013
NCT04811833 Withdrawn Gastrointestinal Anastomosis Using MonoPlus® Suture July 2022 December 2023
NCT01031056 Withdrawn Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers January 2010 January 2099
MeSH unique ID (MeSH (Medical Subject Headings))
D005770