Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (MRP4) via PGE2-dependent pathway.
Pubmed
24909729
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0499678437694072
Drugs