Annotation Detail
Information
- Associated Genes
- PTGS2
- Associated Variants
-
PTGS2 MUTATION
PTGS2 MUTATION - Associated Disease
- ulcerative colitis
- Source Database
- DisGeNET
- Description
- (i) Endoscopically normal appearing colonic mucosa of patients with UC-IR remains abnormal: CLE demonstrates impaired crypt regeneration, persistent inflammation, distinct abnormalities in angioarchitecture and increased vascular permeability; molecular imaging showed increased COX2 and mtDNA mutations; (ii) CLE may serve as a new gold standard for the assessment of mucosal healing in UC.
- Pubmed
- 25827810
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree,LHGDN,RGD
- DisGENET score for the Gene Disease association
- 0.0859816527074308
Drugs