oligodendroglioma (Cancer)

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Information
Disease name
oligodendroglioma
Disease ID
DOID:3181
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03180502 Active, not recruiting Phase 2 Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma August 2, 2017 January 2030
NCT02549833 Active, not recruiting Phase 1 Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma October 17, 2016 August 31, 2024
NCT00165360 Completed Phase 2 Prolonged Daily Temozolomide for Low-Grade Glioma September 2001 September 2009
NCT01609790 Completed Phase 2 Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors June 4, 2012 May 20, 2022
NCT00080054 Completed Phase 1 A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas
NCT00392171 Completed Phase 2 The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601) June 9, 2006 September 15, 2009
NCT00575887 Completed Phase 2 Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma August 2006 March 2009
NCT00717210 Completed Phase 3 Randomized Phase III Study of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide June 1999 March 2008
NCT00874861 Completed Early Phase 1 HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas April 2009 November 2013
NCT00009035 Completed Natural History of Patients With Brain and Spinal Cord Tumors January 22, 2001 September 11, 2018
NCT02530320 Completed Phase 2 Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved October 25, 2015 March 2020
NCT02747407 Completed Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors May 2016 September 9, 2021
NCT02871843 Completed Phase 1 RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic Gliomas February 14, 2017 September 19, 2021
NCT02903784 Completed N/A Neural Basis of Language Processing September 2012 September 2016
NCT03900689 Completed Social Determinants of Health in Glioblastoma Population May 22, 2019 March 27, 2022
NCT06439420 Not yet recruiting Phase 2 CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial July 1, 2024 November 30, 2026
NCT06241391 Not yet recruiting N/A Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas February 2024 February 2025
NCT05513859 Not yet recruiting N/A Investigational Imaging Technique During Brain Surgery June 30, 2024 June 23, 2025
NCT06161974 Not yet recruiting Phase 2 Study of Olutasidenib and Temozolomide in HGG June 2024 June 2035
NCT06038760 Recruiting Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO) October 12, 2023 December 1, 2025
NCT05331521 Recruiting Phase 3 A Clinical Study to Improve Brain Function and Quality of Life of Patients With Newly Diagnosed Brain Tumors (Gliomas). April 7, 2021 March 31, 2029
NCT01849952 Recruiting Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas February 28, 2020 May 2024
NCT02372409 Recruiting Phase 2 Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors August 14, 2015 August 31, 2030
NCT05956821 Recruiting Phase 1/Phase 2 Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age August 1, 2024 December 1, 2029
NCT03152318 Recruiting Phase 1 A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 July 18, 2017 December 2025
NCT03796273 Recruiting Early Phase 1 Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases March 13, 2019 September 2024
NCT04047264 Recruiting N/A Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies January 1, 2020 September 1, 2027
NCT04304300 Recruiting Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes December 10, 2019 May 2026
NCT04541082 Recruiting Phase 1 Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms October 26, 2020 February 2025
NCT04623931 Recruiting Phase 2 Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas January 30, 2020 December 31, 2026
NCT04648462 Recruiting Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology January 1, 2018 January 1, 2035
NCT04702581 Recruiting Phase 3 A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery December 7, 2021 December 2030
NCT05190172 Recruiting N/A PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas January 14, 2022 December 31, 2041
NCT01649830 Recruiting Phase 3 Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma July 2012 August 2026
NCT05345002 Recruiting Phase 2 All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma November 16, 2022 June 1, 2027
NCT05512351 Recruiting Phase 2 Sintilimab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for ctDNAlevel- Relapse and Clinical-relapse Oligodendroglioma December 23, 2022 December 2026
NCT05561374 Recruiting Phase 1 Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma April 17, 2023 August 15, 2024
NCT05624736 Recruiting Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning November 20, 2022 May 1, 2025
NCT02924038 Terminated Phase 1 A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) April 3, 2017 December 31, 2022
NCT00360828 Terminated Phase 2 Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas February 2006 October 2010
NCT00389090 Terminated Phase 2 A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma October 2006 February 2009
NCT02764151 Terminated Phase 1 First in Patient Study for PF-06840003 in Malignant Gliomas September 9, 2016 December 26, 2018
NCT00031538 Terminated Genetic Analysis of Brain Tumors March 1, 2002 April 29, 2015
NCT01836549 Terminated Phase 2 Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors March 2013 April 2016
NCT00035373 Terminated Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols April 19, 2002 April 29, 2015
NCT01089244 Unknown status FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma June 2008 December 2015
NCT03896958 Unknown status The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) March 21, 2019 March 12, 2024
NCT02209428 Unknown status Phase 2 A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas June 2014 May 2019
NCT00591058 Unknown status Phase 1 Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma February 2008 February 2010
NCT00683761 Unknown status Phase 1/Phase 2 A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma August 2008 April 2010
NCT04843085 Unknown status Proteomic Characterization of Aggressive Oligodendrogliomas September 30, 2020 September 2023
NCT04970615 Unknown status Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed Models May 15, 2021 December 15, 2023
NCT04105374 Withdrawn Phase 2/Phase 3 Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma January 31, 2020 November 30, 2030
NCT02976441 Withdrawn Early Phase 1 Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas January 2017 February 2018
NCT03014804 Withdrawn Phase 2 Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen Vaccine and Nivolumab in Treating Patients With Recurrent Glioblastoma December 1, 2019 December 1, 2022
NCT03353896 Withdrawn N/A NovoTTF-200A Device in Treating Patients With Newly Diagnosed High Risk Oligodendroglioma December 15, 2017 December 8, 2020
NCT03649464 Withdrawn Phase 1/Phase 2 Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants August 2022 August 2025
Disase is a (Disease Ontology)
DOID:3070
Cross Reference ID (Disease Ontology)
GARD:9953
Cross Reference ID (Disease Ontology)
ICDO:9450/3
Cross Reference ID (Disease Ontology)
MESH:D009837
Cross Reference ID (Disease Ontology)
NCI:C3288
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0751396
Exact Synonym (Disease Ontology)
oligodendroglial neoplasm
Exact Synonym (Disease Ontology)
oligodendroglial tumor
MeSH unique ID (MeSH (Medical Subject Headings))
D009837