ovarian hyperstimulation syndrome

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Information
Disease name
ovarian hyperstimulation syndrome
Disease ID
DOID:5425
Description
"An ovarian disease that is characterized by cystic enlargement of the ovaries and a fluid shift from the intravascular to the third space and has_symptom abdominal pain, has_symptom nausea and has_symptom vomiting. This disease is an iatrogenic complication of assisted reproduction technology." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205536/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05638529 Active, not recruiting Phase 4 Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome May 1, 2019 December 31, 2023
NCT02670304 Completed Phase 4 Preventive Application of Letrozole Decrease Incidence of Early Onset of OHSS January 2012 August 2013
NCT00349258 Completed Phase 4 The Use of GnRH Agonist Trigger in the Prevention of OHSS August 2004 May 2006
NCT02200952 Completed Luteal Phase Supplementation With Recombinant LH After GnRh Agonist Oocytes Triggering in Women at Risk of OHSS June 30, 2013 June 30, 2014
NCT06333691 Completed N/A Comparative Study Between Calcium Gluconate With Diosmin, Cabergoline and Cabergoline With Diosmin October 1, 2022 February 15, 2024
NCT00329693 Completed Phase 2 Study Assessing the Effect of 3-week Treatment With One of Three Oral Doses of Quinagolide June 2006 May 2008
NCT00440258 Completed Phase 3 Cabergoline Reduces OHSS April 2004 July 2006
NCT00480337 Completed N/A In Vitro Maturation of Immature Oocytes
NCT00665041 Completed Phase 2 Tolerability of Quinagolide in a Dose-titration Regimen in Oocyte Donors at Risk of Developing Ovarian Hyperstimulation Syndrome May 2008 October 2008
NCT00756028 Completed Phase 4 Short Versus Long Protocol for IVF and IVF+ICSI January 2009 December 2015
NCT03876145 Completed N/A The Four Methods of Ovarian Stimulation in Patients With Polycystic Ovarian Syndrome November 12, 2016 November 20, 2020
NCT03996434 Completed Phase 4 Coasting Versus Antagonist Protocol in Patients at High Risk of OHSS July 1, 2019 November 20, 2019
NCT04351126 Completed Phase 2 Management of Ovarian Hyperstimulation Syndrome as a State of Defective Mineralocorticoid Response April 1, 2019 February 29, 2020
NCT00835523 Completed Ovarian Hyperstimulation Syndrome (OHSS) Prevention With Agonist May 2008 July 2010
NCT00867659 Completed N/A The Role of Cetrotide Acetate in Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in Oocyte Donors March 2009 October 2011
NCT05362734 Completed Freeze All Strategy Versus Fresh Embryo Transfer After GnRH Analogue Trigger January 1, 2012 December 31, 2020
NCT01009567 Completed Phase 1/Phase 2 Compare the Efficacy of Human Albumin With Cabergoline to Prevent Ovarian Hyper Stimulation in Assisted Reproductive Technology (ART) Program June 2009 July 2013
NCT01014104 Completed Phase 1/Phase 2 Administration of Methylprednisolone for Prevention of Ovarian Hyper Stimulation Syndrome October 2009 December 2010
NCT01268761 Completed Phase 3 GnRH Antagonist for Treatment of Early Ovarian Hyperstimulation Syndrome April 2012 July 2013
NCT01427335 Completed Phase 3 Calcium for Prevention of Ovarian Hyperstimulation Syndrome October 2011 September 2013
NCT01477970 Completed Double GnRH Antagonist Daily Dose in Hyperresponding IVF/ICSI Cycles May Prevent the OHSS February 2009 February 2010
NCT01500863 Completed Phase 4 Endometrial Receptivity After GnRH Agonist Triggering November 2011
NCT01535859 Completed Phase 3 Study of Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in In Vito Fertilization Cycles and Derivation of OHSS Biomarkers April 2012 June 2016
NCT01569256 Completed N/A Ovarian Hyperstimulation Syndrome and Cabergoline March 2008 March 2009
NCT01815138 Completed Phase 4 Co-administration of Low Dose hCG at the Time of GnRH Agonist Trigger or 35 Hours Later for the Prevention of OHSS March 2013 October 2016
NCT05588635 Completed Association Between Live Birth Rate and Serum Progesterone During Hormonal Replacement Therapy November 1, 2019 March 1, 2021
NCT02686151 Not yet recruiting Phase 3 The Letrozole Administration During Luteal Phase December 2023 December 2024
NCT03794037 Suspended Phase 2 Montelukast for Prevention & Treatment of OHSS December 5, 2018 December 2023
NCT02701452 Terminated N/A Ovarian Hyperstimulation Syndrome in Patients Triggered by GnRH Agonist for Excessive Follicular Response February 26, 2016 January 1, 2019
NCT01606709 Terminated Phase 4 Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation April 2012 December 2014
NCT01714648 Terminated Phase 4 Can GnRH Agonist Trigger Prevent Ovarian Hyperstimulation Syndrome? November 2012 January 2014
NCT02610608 Terminated Medical Assistance for the Procreation and Risk of Thrombosis. February 2, 2016 November 20, 2016
NCT04797338 Unknown status Phase 4 Gonadotropin Releasing Hormone Agonist (GnRHa) Versus Estrogen and Progesterone for Luteal Support in High Responders December 29, 2017 September 30, 2021
NCT00417144 Unknown status Phase 4 Comparison Between GnRH Agonist and GnRH Antagonist Protocols of Ovarian Stimulation in PCOS Patients November 2003 May 2007
NCT02084940 Unknown status Long Acting GnRH Antagonist in PCOS Women Undergoing IVF March 2014 February 2015
NCT02202278 Unknown status Study of Serum Levels of Oxidative Stress Markers in Ovarian Hyperstimulation Patients June 2014 October 2014
NCT02329483 Unknown status Monitoring the Early Follicular Phase With Androstenedione in Low-dose Step-up Ovulation Induction in High Responders December 2014 June 2015
NCT02392520 Unknown status N/A Luteal Antagonist Versus Conventional Treatment in Women With Severe Early Ovarian Hyperstimulation Syndrome (OHSS) May 2015 December 2016
NCT02620605 Unknown status Phase 3 The Influence of Timing of Cabergoline Initiation on Prevention of OHSS December 20, 2017 April 2019
NCT02846493 Unknown status Phase 2 Efficacy and Safety of Dexamethasone Prevention for Patients of Ovarian Hyperstimulation Syndrome August 2016 June 2018
NCT03071172 Unknown status Phase 3 Clinical Study of Recombinant Human Follitropin for Injection Assisted in COH Assisted IVF-ET March 2017 May 2018
NCT03188471 Unknown status Phase 4 Preventive Application of GnRH Antagonist on Early OHSS January 2017 March 2018
NCT00119925 Unknown status N/A 'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists" October 2005 May 2009
NCT05198128 Unknown status N/A Ovarian Hyperstimulation Syndrome Using Calcium Infusion March 1, 2022 May 10, 2023
NCT01979341 Withdrawn N/A The Effect of a Dual Trigger on Intracytoplasmic Sperm Injection (ICSI) Reproductive Outcomes October 2013 September 2016
NCT00617864 Withdrawn N/A The Effect of Human Albumin Infusion on VEGF Levels in Women at Risk for Ovarian Hyperstimulation Syndrome September 2007
NCT00365027 Withdrawn N/A Transfer of Fresh Versus Frozen/Thawed Embryos in IVF Cycles Where GnRH Agonist is Utilized for Oocyte Maturation.
Disase is a (Disease Ontology)
DOID:1100
Cross Reference ID (Disease Ontology)
MESH:D016471
Cross Reference ID (Disease Ontology)
MIM:608115
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:129635004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0085083
Exact Synonym (Disease Ontology)
secondary Meig's syndrome
MedGen concept unique identifier (MedGen Concept name)
C0085083
MedGen unique identifier (MedGen Concept name)
38966
MeSH unique ID (MeSH (Medical Subject Headings))
D016471