Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
Associated Disease
Enzyme inhibition disorder
Source Database
DisGeNET
Description
Taken together, the results obtained here demonstrated that i) CBDA had dual inhibitory effects on COX-2 through down-regulation and enzyme inhibition, and ii) CBDA may possess the ability to suppress genes that are positively involved in the metastasis of cancer cells in vitro.
Pubmed
25242400
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs