Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
Associated Disease
adenoma
Source Database
DisGeNET
Description
Loss of IHH from Apc(HET) mice changed the composition of the adenoma stroma; cells that expressed α-smooth muscle actin or desmin were lost, along with expression of cyclooxygenase-2, and the number of vimentin-positive cells increased.
Pubmed
25307863
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0488406381909087
Drugs