Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
PTGS2 MUTATION
PTGS2 MUTATION
PTGS2 p.Gly587Arg (p.G587R) ( ENST00000367468.10, ENST00000680451.1 )
PTGS2 p.Gly587Arg (p.G587R) ( ENST00000680451.1, ENST00000367468.10 )
Associated Disease
Squamous cell carcinoma of esophagus
Source Database
DisGeNET
Description
Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic activity and risk of esophageal squamous-cell carcinoma.
Pubmed
19347867
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.126786046802008
Year of publication
2009
Drugs