Annotation Detail
Information
- Associated Genes
- PTGS2
- Associated Variants
-
PTGS2 MUTATION
PTGS2 MUTATION - Associated Disease
- CATARACT, ANTERIOR POLAR
- Source Database
- DisGeNET
- Description
- Downregulation of fibronectin, Slug, and cyclooxygenase-2 (COX-2) expression and upregulation of E-cadherin expression were induced in human PCO-attached LECs transfected with miR-181a mimics and miR-181a-overexpressing LECs obtained from patients with anterior polar cataracts.
- Pubmed
- 25626972
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs