chr16:55423612:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr16:55,423,612-55,540,603
hg38 chr16:55,389,700-55,506,691 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.032 squamous cell carcinoma Determinations of the mRNA levels, real-time polymerase chain reaction and promo... BeFree,GAD,LHGDN 25109417 Detail
<0.001 Carcinoma, Transitional Cell NA BeFree Detail
0.003 hypertrophic cardiomyopathy NA LHGDN Detail
0.007 Cardiovascular Diseases In this study, the possible association between MMP-9 and MMP-2 functional promo... BeFree,LHGDN 25416694 Detail
0.002 Carotid Artery Diseases NA GAD Detail
0.005 carotid stenosis NA GAD,LHGDN Detail
0.003 CNS disorder NA BeFree,LHGDN Detail
0.081 intracranial aneurysm NA BeFree,RGD Detail
0.080 brain ischemia NA RGD Detail
0.080 Transient ischemic attack NA RGD Detail
0.002 Malignant tumor of cervix Stroma cell induced transcription of matrix metalloprotease 1 (MMP1) and matrix ... BeFree 26006035 Detail
0.005 Uterine Cervical Neoplasm NA BeFree,GAD,LHGDN Detail
<0.001 Chlamydia Infections NA BeFree Detail
<0.001 Cholangitis, Sclerosing NA BeFree Detail
<0.001 cholelithiasis NA BeFree Detail
0.080 cholestasis NA RGD Detail
0.001 chondrosarcoma The results generated by this study may have important clinical significance in ... BeFree 25145279 Detail
0.002 chorioamnionitis NA GAD Detail
0.001 choriocarcinoma NA BeFree Detail
<0.001 Churg-Strauss syndrome NA BeFree Detail
0.002 cleft lip NA GAD Detail
0.002 cleft palate NA GAD Detail
<0.001 ulcerative colitis NA BeFree Detail
0.006 Colonic Neoplasms NA BeFree,LHGDN Detail
0.006 colorectal carcinoma Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes an... BeFree 24998576 Detail
0.221 Colorectal Neoplasms NA BeFree,CTD_human,LHGDN,RGD Detail
0.080 conjunctivitis NA RGD Detail
0.002 Connective Tissue Diseases NA GAD Detail
0.003 corneal ulcer NA LHGDN Detail
0.004 Coronary Arteriosclerosis Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A... BeFree,GAD 26166126 Detail
0.009 Coronary heart disease Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A... BeFree,GAD,LHGDN 26166126 Detail
<0.001 cutis laxa NA BeFree Detail
0.003 adenoid cystic carcinoma NA LHGDN Detail
<0.001 cystic fibrosis NA BeFree Detail
<0.001 Phyllodes Tumor NA BeFree Detail
<0.001 Cyst NA BeFree Detail
0.080 Dementia, Vascular NA RGD Detail
0.003 Dengue Fever NA LHGDN Detail
<0.001 dental caries NA BeFree Detail
0.003 dermatitis NA LHGDN Detail
0.123 Nasopharyngeal carcinoma The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... BeFree 25481674 Detail
0.003 dermatomyositis NA LHGDN Detail
0.002 Diabetes At baseline, there were no effects of diabetes on MMP or TIMP mRNA or protein. m... BeFree 24903024 Detail
0.005 diabetes mellitus At baseline, there were no effects of diabetes on MMP or TIMP mRNA or protein. m... BeFree,GAD 24903024 Detail
0.120 Diabetes Mellitus, Experimental NA CTD_human Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent At baseline, there were no effects of diabetes on MMP or TIMP mRNA or protein. m... BeFree,GAD 24903024 Detail
0.002 Diabetic Angiopathies NA GAD Detail
0.004 Diabetic Nephropathy NA BeFree,LHGDN Detail
0.120 Diabetic Neuropathies NA CTD_human Detail
0.003 diabetic retinopathy NA BeFree,GAD Detail
<0.001 diverticulitis NA BeFree Detail
0.003 Muscular Dystrophy, Duchenne NA BeFree,LHGDN Detail
<0.001 Dwarfism NA BeFree Detail
0.080 Experimental Autoimmune Encephalomyelitis NA RGD Detail
<0.001 endocarditis NA BeFree Detail
0.011 Endometrial Neoplasms NA GAD,LHGDN Detail
0.114 endometriosis NA BeFree,GAD,LHGDN,RGD Detail
0.004 Esophageal Neoplasms Androgen receptor promotes esophageal cancer cell migration and proliferation vi... BeFree,GAD 25724186 Detail
0.002 Fetal Diseases NA GAD Detail
0.003 Fetal Growth Retardation NA LHGDN Detail
0.002 Fetal Membranes, Premature Rupture NA GAD Detail
<0.001 Nonproliferative fibrocystic disease NA BeFree Detail
<0.001 breast fibrocystic disease NA BeFree Detail
0.002 fibrosarcoma Our experimental data demonstrated that these two microRNAs inhibited the transl... BeFree 25545756 Detail
0.080 Fibrosis NA RGD Detail
<0.001 Giant Cell Tumors NA BeFree Detail
<0.001 Gingival Diseases NA BeFree Detail
<0.001 Glaucoma, Open-Angle NA BeFree Detail
0.130 glioblastoma Interplay of VEGFa and MMP2 regulates invasion of glioblastoma. BeFree,CTD_human,LHGDN 25213694 Detail
0.130 glioblastoma A significant decline of MMP-9 and MMP-2 secretion in cultured U87MG was detecte... BeFree,CTD_human,LHGDN 25256634 Detail
0.130 glioblastoma Our experimental data demonstrated that these two microRNAs inhibited the transl... BeFree,CTD_human,LHGDN 25545756 Detail
0.104 Glioma These results suggest that Ryk is important for the Wnt-5a-dependent induction o... BeFree,LHGDN,RGD 24621529 Detail
0.104 Glioma In conclusion, our data suggest that SERPINB1 negatively regulates glioma cell m... BeFree,LHGDN,RGD 24968089 Detail
0.104 Glioma Moreover, knockdown of HIWI inhibited the migration and invasion of glioma cells... BeFree,LHGDN,RGD 25269862 Detail
0.104 Glioma Knockdown of miR-155 enhanced the anticancer effect of TMZ on glioma by targetin... BeFree,LHGDN,RGD 25535908 Detail
0.104 Glioma Silencing of the tumor suppressor gene WNK2 is associated with upregulation of M... BeFree,LHGDN,RGD 25596741 Detail
0.003 glomerulonephritis NA LHGDN Detail
0.080 Focal glomerulosclerosis NA RGD Detail
<0.001 goiter NA BeFree Detail
0.002 Graft Occlusion, Vascular NA GAD Detail
0.080 Cardiomegaly NA RGD Detail
0.085 Heart failure NA GAD,RGD Detail
0.001 congestive heart failure NA BeFree Detail
<0.001 hemochromatosis NA BeFree Detail
0.003 Hemorrhage NA LHGDN Detail
<0.001 hepatitis A NA BeFree Detail
<0.001 hepatitis B NA BeFree Detail
<0.001 Hepatitis, Chronic NA BeFree Detail
<0.001 Hepatosplenomegaly NA BeFree Detail
<0.001 HIV Infections NA BeFree Detail
0.003 Hodgkin Disease NA LHGDN Detail
<0.001 HTLV-I Infections NA BeFree Detail
0.003 Huntington disease NA LHGDN Detail
<0.001 Hydatidiform mole NA BeFree Detail
<0.001 Hypercholesterolemia, Familial NA BeFree Detail
0.083 Hyperplasia NA LHGDN,RGD Detail
0.002 Hypersensitivity NA GAD Detail
0.211 Hypertensive disease In this study, the possible association between MMP-9 and MMP-2 functional promo... BeFree,CTD_human,GAD,LHGDN,RGD 25416694 Detail
<0.001 pulmonary hypertension NA BeFree Detail
0.080 renal hypertension NA RGD Detail
<0.001 Immunologic Deficiency Syndromes NA BeFree Detail
0.127 Inflammation NA CTD_human,GAD,LHGDN Detail
0.003 Inflammatory Bowel Diseases NA BeFree,LHGDN Detail
0.002 Intervertebral Disk Displacement NA GAD Detail
0.081 ischemia NA BeFree,RGD Detail
<0.001 arthropathy NA BeFree Detail
<0.001 keratoconus NA BeFree Detail
<0.001 actinic keratosis NA BeFree Detail
0.006 Kidney Diseases NA BeFree,LHGDN Detail
<0.001 Kidney Failure, Acute NA BeFree Detail
0.003 Kidney Failure, Chronic NA BeFree,GAD Detail
<0.001 Kidney Neoplasm NA BeFree Detail
0.002 Premature Obstetric Labor NA GAD Detail
0.006 Fibroid Tumor NA BeFree,LHGDN Detail
0.003 leiomyosarcoma NA LHGDN Detail
0.120 Leishmaniasis, Cutaneous NA CTD_human Detail
0.001 leukemia NA BeFree Detail
<0.001 acute monocytic leukemia NA BeFree Detail
0.004 Leukemia, Myelocytic, Acute NA BeFree,LHGDN Detail
<0.001 Myeloid Leukemia, Chronic NA BeFree Detail
<0.001 Leukemia, T-Cell The spread and metastases of ATL as well as other tumors has been associated wit... BeFree 25189759 Detail
<0.001 Adult T-Cell Lymphoma/Leukemia The spread and metastases of ATL as well as other tumors has been associated wit... BeFree 25189759 Detail
<0.001 leukopenia NA BeFree Detail
0.003 lichen planus NA LHGDN Detail
<0.001 liposarcoma NA BeFree Detail
0.205 liver cirrhosis NA CTD_human,GAD,RGD Detail
0.120 Liver Cirrhosis, Alcoholic NA CTD_human Detail
0.080 Biliary cirrhosis NA RGD Detail
0.120 Liver Cirrhosis, Experimental NA CTD_human Detail
0.003 Liver diseases NA BeFree,LHGDN Detail
0.006 Liver neoplasms We also investigated the relationship of MMP-2/-9 and TIMP-1/-2 expression at bo... BeFree,GAD,LHGDN 25036133 Detail
0.080 Liver Neoplasms, Experimental NA RGD Detail
<0.001 Lung diseases In this regard, the aim of the present study was to evaluate and compare sputum ... BeFree 24415566 Detail
0.005 Chronic Obstructive Airway Disease NA BeFree,GAD Detail
0.023 Lung Neoplasms NA BeFree,GAD,LHGDN Detail
<0.001 Lupus Vulgaris In this study, the possible association between MMP-9 and MMP-2 functional promo... BeFree 25416694 Detail
<0.001 Lupus Erythematosus, Discoid In this study, the possible association between MMP-9 and MMP-2 functional promo... BeFree 25416694 Detail
0.120 lupus nephritis NA BeFree,CTD_human Detail
<0.001 lymphoma NA BeFree Detail
0.002 Lymphoma, Non-Hodgkin NA GAD Detail
<0.001 Machado-Joseph disease NA BeFree Detail
<0.001 Mycetoma NA BeFree Detail
0.013 Malignant neoplasm of stomach Pretreatment with helenalin, a nuclear factor-κB (NF-κB) inhibitor, was proved t... BeFree,GAD 24905806 Detail
0.013 Malignant neoplasm of stomach MiR-29s (miR-29a, miR-29b and miR-29c) had been approved that they decreased in ... BeFree,GAD 25428377 Detail
0.013 Malignant neoplasm of stomach Combined treatment with p38 activator partially blocked the antimetastatic effec... BeFree,GAD 25502212 Detail
0.013 Malignant neoplasm of stomach Functional analysis studies revealed that ectopic expression of miR-133a reduced... BeFree,GAD 25620172 Detail
0.013 Malignant neoplasm of stomach WISP-2 suppressed GC cell metastasis through reversing EMT and suppressing the e... BeFree,GAD 26291058 Detail
0.080 Mammary Neoplasms, Experimental NA RGD Detail
0.120 Mandibular Diseases NA CTD_human Detail
0.120 Marfan syndrome NA CTD_human Detail
0.120 Maxillary Diseases NA CTD_human Detail
<0.001 medulloblastoma NA BeFree Detail
0.038 melanoma A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces m... BeFree,LHGDN 24246091 Detail
0.038 melanoma The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlati... BeFree,LHGDN 25313763 Detail
0.038 melanoma Cleaved CD147 shed from the surface of malignant melanoma cells activates MMP2 p... BeFree,LHGDN 25503136 Detail
0.038 melanoma Induction of MDA-9/syntenin in melanoma was found to occur in a thrombin-indepen... BeFree,LHGDN 25505176 Detail
0.004 meningioma NA BeFree,LHGDN Detail
0.080 Meningitis, Pneumococcal NA RGD Detail
0.003 viral meningitis NA LHGDN Detail
<0.001 Mesothelioma NA BeFree Detail
0.002 Metaplasia NA GAD Detail
<0.001 Monoclonal Gammopathy of Undetermined Significance NA BeFree Detail
0.002 Moyamoya disease NA GAD Detail
0.003 Mucocutaneous Lymph Node Syndrome This correlated with reduced expression of the Erk target gene Zeb1 and the Zeb1... BeFree,GAD 25174397 Detail
0.004 multiple myeloma NA BeFree,LHGDN Detail
0.003 multiple sclerosis NA BeFree,GAD Detail
<0.001 myopathy NA BeFree Detail
<0.001 muscular dystrophy NA BeFree Detail
0.002 Musculoskeletal Diseases NA GAD Detail
<0.001 mycosis fungoides NA BeFree Detail
0.211 myocardial infarction NA BeFree,CTD_human,GAD,LHGDN,RGD Detail
0.080 Myocardial Reperfusion Injury NA RGD Detail
0.003 myocarditis NA BeFree,LHGDN Detail
0.005 myopia NA BeFree,GAD Detail
0.007 Nasal Polyps NA BeFree,GAD,LHGDN Detail
0.120 Nasopharyngeal Neoplasms NA CTD_human Detail
0.120 Neoplasm Invasiveness NA CTD_human Detail
0.289 Neoplasm Metastasis The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenua... BeFree,CTD_human,LHGDN,RGD 25004182 Detail
0.289 Neoplasm Metastasis These findings provide a mechanistic explanation for human studies linking incre... BeFree,CTD_human,LHGDN,RGD 25019290 Detail
0.289 Neoplasm Metastasis This study aims to investigate the impacts of CO2 pneumoperitoneum on the growth... BeFree,CTD_human,LHGDN,RGD 25141992 Detail
0.289 Neoplasm Metastasis Restoration of TFPI-2 counteracted the invasiveness of OSCC by inhibiting the en... BeFree,CTD_human,LHGDN,RGD 25179542 Detail
0.289 Neoplasm Metastasis The spread and metastases of ATL as well as other tumors has been associated wit... BeFree,CTD_human,LHGDN,RGD 25189759 Detail
0.289 Neoplasm Metastasis HP1β suppresses metastasis of human cancer cells by decreasing the expression an... BeFree,CTD_human,LHGDN,RGD 25201136 Detail
0.289 Neoplasm Metastasis Stromal matrix metalloproteinase 2 regulates collagen expression and promotes th... BeFree,CTD_human,LHGDN,RGD 25469981 Detail
0.289 Neoplasm Metastasis Our experimental results suggest that HCS has some anti-metastasis potential to ... BeFree,CTD_human,LHGDN,RGD 25496480 Detail
0.289 Neoplasm Metastasis Systemic delivery of protein nanocages bearing CTT peptides for enhanced imaging... BeFree,CTD_human,LHGDN,RGD 25547485 Detail
0.289 Neoplasm Metastasis The inverse correlation of MMP-2 and miR-328 was also observed in tumor specimen... BeFree,CTD_human,LHGDN,RGD 25605016 Detail
0.289 Neoplasm Metastasis Mechanism dissection found that knocking-down TR4 in PCa cells suppressed metast... BeFree,CTD_human,LHGDN,RGD 25623427 Detail
0.289 Neoplasm Metastasis GOLPH3 overexpression is closely correlated with poor prognosis in human non-sma... BeFree,CTD_human,LHGDN,RGD 25659977 Detail
0.289 Neoplasm Metastasis Resistant cells expressed higher levels of genes coding for cancer stem cell mar... BeFree,CTD_human,LHGDN,RGD 25725450 Detail
0.289 Neoplasm Metastasis Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nud... BeFree,CTD_human,LHGDN,RGD 25863127 Detail
0.289 Neoplasm Metastasis The present study demonstrated that GRP78 plays important roles in invasion and ... BeFree,CTD_human,LHGDN,RGD 25976624 Detail
0.289 Neoplasm Metastasis WISP-2 suppressed GC cell metastasis through reversing EMT and suppressing the e... BeFree,CTD_human,LHGDN,RGD 26291058 Detail
0.001 gallbladder carcinoma Multidimensional reduction analysis revealed LXR-β (rs3546355 G &gt; A, rs269512... BeFree 24863943 Detail
0.001 Malignant neoplasm of gallbladder Multidimensional reduction analysis revealed LXR-β (rs3546355 G &gt; A, rs269512... BeFree 24863943 Detail
0.003 neuroblastoma In addition, TLX is coexpressed with the migratory neural progenitor markers CD1... BeFree 25356871 Detail
0.003 Neuromuscular Diseases NA LHGDN Detail
<0.001 neutropenia NA BeFree Detail
0.120 Nose Neoplasms NA CTD_human Detail
0.001 obesity NA BeFree Detail
0.080 ocular hypertension NA RGD Detail
<0.001 Opportunistic Infections NA BeFree Detail
<0.001 optic neuritis MMP-2 -1575G/A polymorphism modifies the onset of optic neuritis as a first pres... BeFree 26298319 Detail
0.123 oral submucous fibrosis NA BeFree,CTD_human,GAD Detail
0.003 Degenerative polyarthritis NA BeFree,GAD Detail
<0.001 Idiopathic Multicentric Osteolyses NA BeFree Detail
0.120 Bone necrosis NA CTD_human Detail
<0.001 osteoporosis NA BeFree Detail
0.007 osteosarcoma Furthermore, we determine the functional relevance of Beclin-1 knockdown to oste... BeFree,LHGDN 25427639 Detail
0.007 osteosarcoma Furthermore, miR-142 inhibited osteosarcoma cell invasion by inducing E-cadherin... BeFree,LHGDN 25530132 Detail
0.007 osteosarcoma Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical... BeFree,LHGDN 25605016 Detail
0.007 osteosarcoma Questions about XY Wen et al. entitled Matrix metalloproteinase 2 expression and... BeFree,LHGDN 25663465 Detail
0.003 Otitis Media with Effusion NA LHGDN Detail
0.007 ovarian carcinoma Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell... BeFree 25141992 Detail
0.007 ovarian carcinoma Matrix metalloproteinase-2 (MMP-2) is closely related to the pathogenesis of ova... BeFree 25347277 Detail
0.007 ovarian carcinoma Our previous study indicated that BCL2-associated athanogene 3 (BAG3) enhances m... BeFree 25738313 Detail
<0.001 Ovarian Cysts NA BeFree Detail
0.014 Pancreatic Neoplasm NA BeFree,LHGDN Detail
0.003 parapsoriasis NA BeFree,GAD Detail
<0.001 Parathyroid Neoplasms NA BeFree Detail
0.003 parotitis NA LHGDN Detail
<0.001 Periodontal Diseases NA BeFree Detail
0.087 periodontitis NA BeFree,GAD,RGD Detail
<0.001 Periodontitis, Juvenile NA BeFree Detail
0.001 pituitary adenoma NA BeFree Detail
<0.001 Pituitary Neoplasms NA BeFree Detail
0.003 Pleural effusion disorder NA LHGDN Detail
<0.001 Pneumoperitoneum In contrast to NM23-H1, MMP-2 expression was significantly higher in CO2 pneumop... BeFree 25141992 Detail
0.083 polycystic ovary syndrome NA LHGDN,RGD Detail
<0.001 polycythemia vera No statistically significant differences were detected between patient (ET+PV) a... BeFree 25684469 Detail
0.003 polyps NA LHGDN Detail
0.002 pre-eclampsia NA GAD Detail
<0.001 Precancerous Conditions NA BeFree Detail
<0.001 Pregnancy Complications NA BeFree Detail
0.002 Pregnancy Complications, Hematologic NA GAD Detail
<0.001 prolactinoma Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: P... BeFree 26071077 Detail
0.017 Prostatic Neoplasms NA BeFree,LHGDN Detail
0.003 pseudoxanthoma elasticum NA BeFree,LHGDN Detail
0.006 psoriasis NA BeFree,GAD Detail
<0.001 pterygium NA BeFree Detail
<0.001 pulmonary alveolar proteinosis NA BeFree Detail
0.080 pulmonary embolism NA RGD Detail
0.081 pulmonary emphysema NA BeFree,RGD Detail
0.123 pulmonary fibrosis NA BeFree,CTD_human,LHGDN Detail
0.001 kidney failure NA BeFree Detail
<0.001 retinal degeneration NA BeFree Detail
<0.001 Retinal Diseases NA BeFree Detail
<0.001 retinal vein occlusion NA BeFree Detail
0.001 rhabdomyosarcoma NA BeFree Detail
0.002 rhinitis NA GAD Detail
<0.001 Salivary Gland Neoplasms However, the mean scores for MMP-2 stain intensity and proportion were significa... BeFree 25412957 Detail
0.003 Kaposi sarcoma NA LHGDN Detail
0.009 systemic scleroderma NA BeFree,GAD,LHGDN Detail
0.003 Shock NA LHGDN Detail
0.002 sinusitis NA GAD Detail
<0.001 Skin Abnormalities Furthermore, the loss of MMP2 activity suggests that fibrotic skin abnormalities... BeFree 25572963 Detail
0.002 Dermatologic disorders NA GAD Detail
0.005 Skin Neoplasms NA GAD,LHGDN Detail
0.002 Spinal Diseases NA GAD Detail
0.003 Stevens-Johnson syndrome NA LHGDN Detail
0.094 Stomach Neoplasms NA BeFree,LHGDN,RGD Detail
0.080 gastric ulcer NA BeFree,RGD Detail
0.086 Cerebrovascular accident NA BeFree,GAD,RGD Detail
0.080 Subarachnoid Hemorrhage NA RGD Detail
0.003 synovial sarcoma NA BeFree,LHGDN Detail
0.003 Takayasu Arteritis NA LHGDN Detail
0.004 Giant Cell Arteritis NA BeFree,LHGDN Detail
<0.001 Thrombocythemia, Essential No statistically significant differences were detected between patient (ET+PV) a... BeFree 25684469 Detail
0.008 Thyroid Neoplasm NA LHGDN Detail
<0.001 Chagas disease NA BeFree Detail
<0.001 tuberous sclerosis NA BeFree Detail
0.080 Ulcer NA RGD Detail
0.005 Uterine Diseases NA GAD Detail
<0.001 Uterine Fibroids NA BeFree Detail
0.003 Uterine hemorrhage NA LHGDN Detail
<0.001 Uterine Prolapse NA BeFree Detail
<0.001 Varicosity NA BeFree Detail
<0.001 vasculitis NA BeFree Detail
0.080 Venous Thrombosis NA RGD Detail
<0.001 Hallopeau-Siemens Disease NA BeFree Detail
0.005 Helicobacter Infections NA GAD Detail
<0.001 Ichthyosis, X-Linked NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
0.003 Lymphoma, T-Cell, Cutaneous NA BeFree,GAD Detail
0.003 Meningitis, Bacterial NA LHGDN Detail
0.003 polymyositis NA LHGDN Detail
<0.001 acute leukemia NA BeFree Detail
<0.001 Alcohol abuse NA BeFree Detail
<0.001 benign neoplasm NA BeFree Detail
<0.001 Chronic sinusitis NA BeFree Detail
0.082 Left Ventricular Hypertrophy NA GAD,RGD Detail
0.001 Small cell carcinoma of lung NA BeFree Detail
0.009 Premature Birth NA GAD Detail
<0.001 Oral Cavity Carcinoma NA BeFree Detail
<0.001 renal fibrosis NA BeFree Detail
<0.001 Myocardial Ischemia NA BeFree Detail
0.002 Adenocarcinoma of lung (disorder) NA BeFree Detail
0.002 esophageal carcinoma Androgen receptor promotes esophageal cancer cell migration and proliferation vi... BeFree 25724186 Detail
0.003 polyneuropathy NA LHGDN Detail
<0.001 hypertensive heart disease NA BeFree Detail
0.003 Malignant neoplasm of mouth NA BeFree,GAD Detail
<0.001 Malignant neoplasm of nasopharynx NA BeFree Detail
0.001 Malignant neoplasm of gallbladder Norcantharidin enhances TIMP‑2 anti‑vasculogenic mimicry activity for human gall... BeFree 25405519 Detail
<0.001 Malignant neoplasm of brain NA BeFree Detail
0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 Secondary malignant neoplasm of bone NA BeFree Detail
<0.001 proliferative diabetic retinopathy NA BeFree Detail
<0.001 Corneal pannus NA BeFree Detail
<0.001 acute myocardial infarction NA BeFree Detail
<0.001 Peritoneal adhesion NA BeFree Detail
<0.001 endometriosis of ovary NA BeFree Detail
<0.001 Intervertebral Disc Degeneration NA BeFree Detail
0.003 Colitis, Ischemic NA BeFree,LHGDN Detail
<0.001 porphyria cutanea tarda NA BeFree Detail
0.080 Right Ventricular Hypertrophy NA RGD Detail
<0.001 Cicatrix, Hypertrophic There was a significant upregulation of the mRNA expression of matrix metallopro... BeFree 25166894 Detail
0.092 Aortic Aneurysm, Abdominal NA BeFree,GAD,RGD Detail
<0.001 Glomerulosclerosis (disorder) NA BeFree Detail
0.005 Tumor Progression Several polymorphisms within the MMP2 promoter region have been reported in case... BeFree 24998576 Detail
0.005 Tumor Progression Matrix metalloproteinase-2 (MMP-2) is involved in degradation of extra-cellular ... BeFree 25313763 Detail
0.005 Tumor Progression Overall, our results reveal a previously undefined role for MMP2 in metastatic o... BeFree 25469981 Detail
0.005 Tumor Progression Experiments in vitro validated that SCRN1 may promote cancer cell proliferation ... BeFree 25814779 Detail
<0.001 Microinvasive tumor NA BeFree Detail
<0.001 follicular adenoma NA BeFree Detail
<0.001 alveolar rhabdomyosarcoma NA BeFree Detail
<0.001 Rhabdomyosarcoma, Embryonal NA BeFree Detail
<0.001 Adenomatous Polyps NA BeFree Detail
<0.001 Follicular thyroid carcinoma NA BeFree Detail
<0.001 Carcinoma, Endometrioid Our aim in the present study was to examine the relationships among BAG3, miR-29... BeFree 25738313 Detail
<0.001 Carcinoma, Lobular NA BeFree Detail
0.081 cholangiocarcinoma NA BeFree,RGD Detail
<0.001 Carcinoma, Large Cell NA BeFree Detail
0.006 Cervical Intraepithelial Neoplasia NA BeFree,GAD,LHGDN Detail
<0.001 uveal melanoma The effects of epigallocatechingallate (EGCG) on the migration and expression of... BeFree 25184134 Detail
<0.001 Lip and oral cavity carcinoma NA BeFree Detail
<0.001 Metastatic malignant neoplasm to brain NA BeFree Detail
<0.001 Fibrillation NA BeFree Detail
0.001 gallbladder carcinoma Norcantharidin enhances TIMP‑2 anti‑vasculogenic mimicry activity for human gall... BeFree 25405519 Detail
0.006 pancreatic carcinoma In conclusion, the present study reveals that the increased expression of OCT4 i... BeFree 25017645 Detail
0.006 pancreatic carcinoma Our results demonstrated that DAPK1 gene over-expression can suppress the prolif... BeFree 25550789 Detail
0.006 pancreatic carcinoma Furthermore, we show that Nodal promotes pancreatic cancer cell migration and in... BeFree 25557170 Detail
0.006 pancreatic carcinoma Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nud... BeFree 25863127 Detail
<0.001 Gastrointestinal Stromal Tumors NA BeFree Detail
0.003 Cancer of Nasopharynx NA BeFree,GAD Detail
<0.001 Hereditary pancreatitis NA BeFree Detail
<0.001 Papillary thyroid carcinoma NA BeFree Detail
0.002 Fibrosis, Liver In liver fibrosis in both human and mouse tissue MMP expression and activity (MM... BeFree 25076423 Detail
<0.001 pelvic inflammatory disease NA BeFree Detail
0.019 Malignant neoplasm of lung Evaluation of matrix metalloproteinase-2 in lung cancer. BeFree,GAD 24415566 Detail
0.019 Malignant neoplasm of lung The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenua... BeFree,GAD 25004182 Detail
0.019 Malignant neoplasm of lung And the lung cancer metastasis factors (MMP-2, MMP-9, VEGF, and CXCR4) were decr... BeFree,GAD 25150396 Detail
0.019 Malignant neoplasm of lung PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated tr... BeFree,GAD 25486572 Detail
<0.001 Lyme Arthritis NA BeFree Detail
<0.001 age related macular degeneration NA BeFree Detail
0.120 Disease Progression NA CTD_human Detail
0.080 Hyperoxia NA RGD Detail
0.083 Sepsis NA LHGDN,RGD Detail
<0.001 Carcinoma, Lewis Lung In the direct anti-metastatic action, antrodan (30-70 μg/mL) was found to signif... BeFree 25583024 Detail
<0.001 Chronic heart failure NA BeFree Detail
<0.001 Chronic Periodontitis NA BeFree Detail
<0.001 Acute ischemic colitis NA BeFree Detail
0.080 Pancreatitis, Acute Necrotizing NA RGD Detail
<0.001 Primary amyloidosis NA BeFree Detail
<0.001 Endometrioma NA BeFree Detail
<0.001 Rhegmatogenous retinal detachment NA BeFree Detail
<0.001 Stage II Colon Cancer NA BeFree Detail
<0.001 Non-small cell lung cancer stage I NA BeFree Detail
<0.001 Metastatic osteosarcoma Matrix metalloproteinase-2 family member expression, a key pathway in osteosarco... BeFree 25065593 Detail
<0.001 gastric adenocarcinoma NA BeFree Detail
<0.001 Metastatic melanoma NA BeFree Detail
0.003 Cancer of Head and Neck NA BeFree,GAD Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
0.002 Squamous cell carcinoma of esophagus In conclusion, this study showed that the MMP2 -1306 TT and MMP9 -1562 CC genoty... BeFree 25966235 Detail
0.002 Squamous cell carcinoma of esophagus The present study demonstrated that GRP78 plays important roles in invasion and ... BeFree 25976624 Detail
<0.001 Adenocarcinoma Of Esophagus NA BeFree Detail
<0.001 Transitional cell carcinoma of bladder NA BeFree Detail
0.001 Conventional (Clear Cell) Renal Cell Carcinoma NA BeFree Detail
<0.001 laryngeal squamous cell carcinoma NA BeFree Detail
<0.001 secondary acute myeloid leukemia NA BeFree Detail
<0.001 Leiomyosarcoma of uterus NA BeFree Detail
<0.001 intraocular lymphoma NA BeFree Detail
0.005 cervix carcinoma Stroma cell induced transcription of matrix metalloprotease 1 (MMP1) and matrix ... BeFree 26006035 Detail
<0.001 Chronic ulcer NA BeFree Detail
<0.001 Superficial ulcer NA BeFree Detail
<0.001 Senile Plaques NA BeFree Detail
<0.001 Caries (morphologic abnormality) NA BeFree Detail
<0.001 High-Grade Squamous Intraepithelial Lesions NA BeFree Detail
<0.001 anaplastic astrocytoma NA BeFree Detail
<0.001 Glaucoma, Primary Open Angle NA BeFree Detail
<0.001 Stable angina NA BeFree Detail
<0.001 Aortic aneurysm without mention of rupture NOS NA BeFree Detail
<0.001 Dissection of aorta NA BeFree Detail
0.003 Chronic liver disease NA BeFree,GAD Detail
<0.001 endometriosis of uterus Increased expression of p21-activated kinase 4 in adenomyosis and its regulation... BeFree 25637478 Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 Large cell carcinoma of lung NA BeFree Detail
<0.001 malignant mesothelioma NA BeFree Detail
0.004 Malignant neoplasm of pancreas In conclusion, the present study reveals that the increased expression of OCT4 i... BeFree 25017645 Detail
0.004 Malignant neoplasm of pancreas Furthermore, we show that Nodal promotes pancreatic cancer cell migration and in... BeFree 25557170 Detail
0.004 Malignant neoplasm of pancreas Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nud... BeFree 25863127 Detail
<0.001 Disseminated Malignant Neoplasm Matrix metalloproteinase 2 (MMP-2) in metastatic cancer tissue, which is associa... BeFree 25547485 Detail
<0.001 Secondary malignant neoplasm of pancreas NA BeFree Detail
<0.001 Cervical intraepithelial neoplasia grade 1 NA BeFree Detail
<0.001 Cervical intraepithelial neoplasia grade 2 NA BeFree Detail
0.017 Malignant neoplasm of prostate MiR-130b suppresses prostate cancer metastasis through down-regulation of MMP2. BeFree,GAD 25154741 Detail
0.017 Malignant neoplasm of prostate Our data showed that knockdown of SPAG9 in prostate cancer cell lines inhibited ... BeFree,GAD 25310386 Detail
0.017 Malignant neoplasm of prostate Adipocyte-derived monocyte chemotactic protein-1 (MCP-1) promotes prostate cance... BeFree,GAD 25917126 Detail
0.003 Endotoxemia NA LHGDN Detail
0.120 Craniofacial Abnormalities NA CTD_human Detail
<0.001 Polyradiculoneuropathy, Chronic Inflammatory Demyelinating NA BeFree Detail
<0.001 Hereditary gingival fibromatosis NA BeFree Detail
<0.001 Growth retardation, Alopecia, Pseudoanodontia and Optic atrophy Furthermore, the loss of MMP2 activity suggests that fibrotic skin abnormalities... BeFree 25572963 Detail
0.005 Osteoarthritis, Knee NA BeFree,GAD,LHGDN Detail
<0.001 lupus erythematosus In this study, the possible association between MMP-9 and MMP-2 functional promo... BeFree 25416694 Detail
<0.001 clear cell meningioma NA BeFree Detail
<0.001 Winchester syndrome (disorder) NA BeFree Detail
<0.001 neuropathy NA BeFree Detail
<0.001 Nevus elasticus NA BeFree Detail
0.002 endometrial carcinoma The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid... BeFree 25308734 Detail
0.002 Secondary malignant neoplasm of liver Our experimental results suggest that HCS has some anti-metastasis potential to ... BeFree 25496480 Detail
0.002 Secondary malignant neoplasm of liver Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nud... BeFree 25863127 Detail
<0.001 Overweight NA BeFree Detail
<0.001 Sleep Apnea, Obstructive Functional polymorphisms in the promoter region of MMP-2 and MMP-9 and susceptib... BeFree 25753939 Detail
0.001 Recurrent tumor NA BeFree Detail
<0.001 Metabolic syndrome X NA BeFree Detail
0.003 Hepatitis B, Chronic NA BeFree,LHGDN Detail
0.003 Hepatitis C, Chronic NA BeFree,GAD Detail
<0.001 Atherosclerotic occlusive disease NA BeFree Detail
0.006 Malignant neoplasm of esophagus Androgen receptor promotes esophageal cancer cell migration and proliferation vi... BeFree,GAD 25724186 Detail
0.003 Hypovolemia NA LHGDN Detail
0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Squamous cell carcinoma of skin Moreover, the suppressive role of miR-199a in cell migration in cSCC cells was a... BeFree 25400809 Detail
<0.001 Malignant glioma NA BeFree Detail
<0.001 primary sclerosing cholangitis NA BeFree Detail
<0.001 Squamous cell carcinoma of mouth NA BeFree Detail
0.004 Osteosarcoma of bone Furthermore, we determine the functional relevance of Beclin-1 knockdown to oste... BeFree 25427639 Detail
0.004 Osteosarcoma of bone Furthermore, miR-142 inhibited osteosarcoma cell invasion by inducing E-cadherin... BeFree 25530132 Detail
0.004 Osteosarcoma of bone Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical... BeFree 25605016 Detail
0.004 Osteosarcoma of bone Questions about XY Wen et al. entitled Matrix metalloproteinase 2 expression and... BeFree 25663465 Detail
<0.001 Aqueous Humor Disorders NA BeFree Detail
0.003 Carcinogenesis While MMP-2 and uPA have been demonstrated to be important mediators of EMMPRIN ... BeFree 24705283 Detail
0.003 Carcinogenesis Several polymorphisms within the MMP2 promoter region have been reported in case... BeFree 24998576 Detail
<0.001 Biliary stricture NA BeFree Detail
<0.001 hyperhomocysteinemia NA BeFree Detail
<0.001 Aggressive periodontitis, generalized MMP-2 -735C/T and MMP-12 357Asn/Ser polymorphisms are not related to GAgP. BeFree 18052707 Detail
0.010 prostate carcinoma MiR-130b suppresses prostate cancer metastasis through down-regulation of MMP2. BeFree 25154741 Detail
0.010 prostate carcinoma Our data showed that knockdown of SPAG9 in prostate cancer cell lines inhibited ... BeFree 25310386 Detail
0.010 prostate carcinoma Adipocyte-derived monocyte chemotactic protein-1 (MCP-1) promotes prostate cance... BeFree 25917126 Detail
0.002 hepatopulmonary syndrome NA GAD Detail
0.002 Epithelial ovarian cancer NA BeFree Detail
<0.001 invasive cancer NA BeFree Detail
0.018 breast carcinoma In the present study, we demonstrate that green tea polyphenols (GTP) and its ma... BeFree 24481780 Detail
0.018 breast carcinoma These findings indicate that GALNT14 contributes to breast cancer invasion by al... BeFree 24962947 Detail
0.018 breast carcinoma Lack of association between the matrix metalloproteinase-2 -1306C>T polymorphism... BeFree 24998547 Detail
0.018 breast carcinoma It has been reported that COX-2 expression is associated with MMP-2 expression i... BeFree 24998576 Detail
0.018 breast carcinoma The his6-rTIMP-1 was bioactive as shown by its proper inhibitory effect on MMP-2... BeFree 24998777 Detail
0.018 breast carcinoma It is known that fibronectin is capable of promoting the expression of MMP-2 in ... BeFree 25208219 Detail
0.018 breast carcinoma Gene expression data in stromal cells of human breast cancers reveal that MMP2 e... BeFree 25469981 Detail
0.018 breast carcinoma Therefore, LASS2/TMSG1 may inhibit growth and invasion of breast cancer cell in ... BeFree 25501280 Detail
0.018 breast carcinoma These results indicate that Ethyl gallate suppresses proliferation and invasion ... BeFree 25522911 Detail
0.018 breast carcinoma Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloprote... BeFree 25656607 Detail
0.018 breast carcinoma Matrix metalloproteinase-9 -1562T allele and its combination with MMP-2 -735 C a... BeFree 25735351 Detail
0.010 Carcinoma of lung Evaluation of matrix metalloproteinase-2 in lung cancer. BeFree 24415566 Detail
0.010 Carcinoma of lung The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenua... BeFree 25004182 Detail
0.010 Carcinoma of lung And the lung cancer metastasis factors (MMP-2, MMP-9, VEGF, and CXCR4) were decr... BeFree 25150396 Detail
0.010 Carcinoma of lung These results suggested that PFIO could suppress the invasion and migration of h... BeFree 25270791 Detail
0.010 Carcinoma of lung PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated tr... BeFree 25486572 Detail
<0.001 Malignant neoplasm of gastrointestinal tract NA BeFree Detail
<0.001 CNS metastases NA BeFree Detail
0.005 Secondary malignant neoplasm of lymph node Functional analysis of cellular proliferative activities, by MTT assay, and inva... BeFree 25216407 Detail
<0.001 Parathyroid Gland Adenocarcinoma NA BeFree Detail
0.007 colon carcinoma Here we report that forced GRP78 expression promotes colon cancer cell migration... BeFree 24314144 Detail
0.007 colon carcinoma The frequency of individuals with MMP2 polymorphisms in colon cancer patients wa... BeFree 24998576 Detail
0.007 colon carcinoma Reduced HP1β expression correlates with the increased level of pro- and active-M... BeFree 25201136 Detail
0.007 colon carcinoma Functional analysis of cellular proliferative activities, by MTT assay, and inva... BeFree 25216407 Detail
0.007 colon carcinoma Secernin-1 contributes to colon cancer progression through enhancing matrix meta... BeFree 25814779 Detail
0.009 stomach carcinoma Pretreatment with helenalin, a nuclear factor-κB (NF-κB) inhibitor, was proved t... BeFree 24905806 Detail
0.009 stomach carcinoma MiR-29s (miR-29a, miR-29b and miR-29c) had been approved that they decreased in ... BeFree 25428377 Detail
0.009 stomach carcinoma Combined treatment with p38 activator partially blocked the antimetastatic effec... BeFree 25502212 Detail
0.009 stomach carcinoma Functional analysis studies revealed that ectopic expression of miR-133a reduced... BeFree 25620172 Detail
0.009 stomach carcinoma WISP-2 suppressed GC cell metastasis through reversing EMT and suppressing the e... BeFree 26291058 Detail
0.004 Carcinoma of bladder Extra virgin olive oil phenols suppress migration and invasion of T24 human blad... BeFree 24918476 Detail
0.004 Carcinoma of bladder In conclusion, the findings of the present study show that naringenin is capable... BeFree 25017119 Detail
0.003 Central neuroblastoma In addition, TLX is coexpressed with the migratory neural progenitor markers CD1... BeFree 25356871 Detail
<0.001 Dissecting aneurysm of the thoracic aorta NA BeFree Detail
0.001 Malignant neoplasm of kidney Interestingly, IR treatment leads to inhibition of matrix metalloproteinase-2 (M... BeFree 25273173 Detail
<0.001 Cardiac defects NA BeFree Detail
<0.001 early pregnancy NA BeFree Detail
<0.001 lymphangioleiomyomatosis NA BeFree Detail
<0.001 malignant peripheral nerve sheath tumor NA BeFree Detail
<0.001 Carcinoma in situ of uterine cervix NA BeFree Detail
0.003 Pregnancy associated hypertension NA LHGDN Detail
<0.001 Invasive breast carcinoma NA BeFree Detail
<0.001 Triple vessel disease NA BeFree Detail
0.120 Drug-Induced Liver Injury NA CTD_human Detail
<0.001 Pelvic Organ Prolapse NA BeFree Detail
<0.001 Cardiomyopathies NA BeFree Detail
<0.001 Stromal Neoplasm NA BeFree Detail
0.004 Hajdu-Cheney syndrome NA BeFree,LHGDN Detail
<0.001 Cerebral Aneurysm NA BeFree Detail
0.010 ovarian neoplasm NA BeFree,LHGDN Detail
<0.001 cancer recurrence NA BeFree Detail
<0.001 Metastatic Prostate Carcinoma NA BeFree Detail
<0.001 cholecystolithiasis NA BeFree Detail
<0.001 Vascular inflammations NA BeFree Detail
0.004 Acute coronary syndrome NA BeFree,LHGDN Detail
<0.001 Invasive Ductal Breast Carcinoma NA BeFree Detail
0.003 Heart Failure, Systolic NA BeFree,GAD Detail
0.010 Malignant neoplasm of ovary Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell... BeFree,GAD 25141992 Detail
0.010 Malignant neoplasm of ovary Matrix metalloproteinase-2 (MMP-2) is closely related to the pathogenesis of ova... BeFree,GAD 25347277 Detail
0.010 Malignant neoplasm of ovary Our previous study indicated that BCL2-associated athanogene 3 (BAG3) enhances m... BeFree,GAD 25738313 Detail
0.003 Squamous cell carcinoma of the head and neck Orthotopic tongue HNSCC xenografts showed excellent ratiometric fluorescent labe... BeFree 25091190 Detail
<0.001 Ductal Carcinoma NA BeFree Detail
0.002 Stenosis NA GAD Detail
<0.001 sarcoma NA BeFree Detail
<0.001 M5b Acute differentiated monocytic leukemia NA BeFree Detail
0.003 gastric cardia adenocarcinoma NA BeFree,GAD Detail
<0.001 High Grade Cervical Intraepithelial Neoplasia NA BeFree Detail
<0.001 Invasive Carcinoma NA BeFree Detail
<0.001 mesenchymal cell neoplasm NA BeFree Detail
<0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
<0.001 Pericytic Neoplasm NA BeFree Detail
0.120 Testicular Germ Cell Tumor NA CTD_human Detail
<0.001 Epithelioma NA BeFree Detail
0.002 renal carcinoma Interestingly, IR treatment leads to inhibition of matrix metalloproteinase-2 (M... BeFree 25273173 Detail
<0.001 Posterior capsule opacification NA BeFree Detail
0.161 Mammary Neoplasms NA BeFree,CTD_human,LHGDN Detail
<0.001 Desmoplastic NA BeFree Detail
0.003 Tumor Angiogenesis Both in vitro and in vivo assays indicated that ablation of endogenous EIF5A2 in... BeFree 25071013 Detail
<0.001 Xenograft Model NA BeFree Detail
0.018 colorectal cancer Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes an... BeFree,GAD 24998576 Detail
<0.001 Neoplasms, Intracranial NA BeFree Detail
<0.001 Chronic Kidney Diseases NA BeFree Detail
<0.001 Renal Insufficiency NA BeFree Detail
<0.001 Tendinosis NA BeFree Detail
<0.001 Adenocarcinoma, Endometrioid Our aim in the present study was to examine the relationships among BAG3, miR-29... BeFree 25738313 Detail
<0.001 Glioblastoma multiforme A significant decline of MMP-9 and MMP-2 secretion in cultured U87MG was detecte... BeFree 25256634 Detail
<0.001 tumor vasculature Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor respo... BeFree 25071013 Detail
<0.001 Peripheral Arterial Diseases NA BeFree Detail
<0.001 Invasive Skin Melanoma NA BeFree Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
<0.001 Aggressive periodontitis, generalized NA BeFree Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
<0.001 Idiopathic Pulmonary Fibrosis NA BeFree Detail
0.562 TORG-WINCHESTER SYNDROME Functional characterisation of a novel mutation affecting the catalytic domain o... BeFree,CLINVAR,CTD_human,MGD,ORPHANET,UNIPROT 25273674 Detail
<0.001 Dyssegmental dysplasia NA BeFree Detail
0.001 uterine corpus cancer The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid... BeFree 25308734 Detail
0.011 coronary artery disease Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A... BeFree,GAD,LHGDN 26166126 Detail
0.003 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree,LHGDN Detail
0.141 liver carcinoma Silencing alpha-fetoprotein inhibits VEGF and MMP-2/9 production in human hepato... BeFree,CTD_human,GAD,LHGDN 24587407 Detail
0.141 liver carcinoma We also investigated the relationship of MMP-2/-9 and TIMP-1/-2 expression at bo... BeFree,CTD_human,GAD,LHGDN 25036133 Detail
0.141 liver carcinoma Reduction in HCC cell migration and invasion is also evident through reversal of... BeFree,CTD_human,GAD,LHGDN 25495189 Detail
0.141 liver carcinoma Mechanistic investigations showed that CYP3A5 overexpression limited MMP2/9 func... BeFree,CTD_human,GAD,LHGDN 25649767 Detail
0.141 liver carcinoma In our study, we tested a matrix metalloproteinase-2 (MPP2) aCPP in delivering h... BeFree,CTD_human,GAD,LHGDN 25671640 Detail
<0.001 Chronic kidney disease stage 5 NA BeFree Detail
<0.001 Mycetoma of foot NA BeFree Detail
<0.001 Hepatitis B and hepatitis C NA BeFree Detail
0.002 Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified NA GAD Detail
0.123 Nasopharyngeal carcinoma The expressions of WNT5A and EMT related factors matrix metalloproteinase-2 of t... BeFree,CTD_human 25066400 Detail
0.123 Nasopharyngeal carcinoma The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... BeFree,CTD_human 25481674 Detail
<0.001 Plaque, Amyloid NA BeFree Detail
0.120 Neointima NA CTD_human Detail
0.120 Cerebral Hemorrhage NA CTD_human Detail
<0.001 Stage II Colon Cancer AJCC v7 NA BeFree Detail
<0.001 Valvular disease NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms NA BeFree Detail
<0.001 Allergic disposition NA BeFree Detail
0.008 Infection NA GAD,LHGDN Detail
<0.001 Portal fibrosis NA BeFree Detail
<0.001 acquired immunodeficiency syndrome NA BeFree Detail
0.019 adenocarcinoma In AC MMP2 had a worsening impact on survival (P = 0.021) and it had independent... BeFree,GAD,LHGDN 25337226 Detail
<0.001 adenoma NA BeFree Detail
<0.001 AIDS Dementia Complex NA BeFree Detail
0.003 Alzheimer's disease NA BeFree,GAD Detail
0.001 ameloblastoma NA BeFree Detail
<0.001 Anaplasia NA BeFree Detail
0.005 Aneurysm NA BeFree,GAD Detail
0.005 aortic aneurysm NA BeFree,LHGDN Detail
0.120 Aortic Diseases NA CTD_human Detail
0.120 Aortic Rupture NA BeFree,CTD_human Detail
<0.001 aortic valve stenosis NA BeFree Detail
<0.001 arteriosclerosis NA BeFree Detail
0.080 Arteriovenous fistula NA RGD Detail
<0.001 Congenital arteriovenous malformation Cultured AVMECs expressed higher angiogenic factors (VEGF, MMP-2) than the contr... BeFree 24771337 Detail
<0.001 Arthralgia NA BeFree Detail
0.005 arthritis NA BeFree,GAD Detail
<0.001 Arthritis, Psoriatic NA BeFree Detail
0.133 rheumatoid arthritis NA BeFree,CTD_human,GAD,LHGDN Detail
0.003 asthma NA BeFree,LHGDN Detail
0.002 Astrocytoma NA BeFree Detail
0.088 atherosclerosis NA BeFree,GAD,LHGDN,RGD Detail
0.005 atrial fibrillation NA GAD Detail
<0.001 biliary atresia NA BeFree Detail
0.008 Malignant neoplasm of urinary bladder Extra virgin olive oil phenols suppress migration and invasion of T24 human blad... BeFree,GAD 24918476 Detail
0.008 Malignant neoplasm of urinary bladder In conclusion, the findings of the present study show that naringenin is capable... BeFree,GAD 25017119 Detail
0.006 Bladder Neoplasm NA BeFree,LHGDN Detail
<0.001 Blast Phase NA BeFree Detail
0.120 Bone Diseases NA BeFree,CTD_human Detail
0.120 Metabolic Bone Disorder NA CTD_human Detail
0.120 Bone neoplasms Serum levels of RANK, OPG, IL-8, IL-6, and the OPG/sRANKL ratio were significant... BeFree,CTD_human 25110097 Detail
<0.001 Brain Neoplasms NA BeFree Detail
0.034 Malignant neoplasm of breast In the present study, we demonstrate that green tea polyphenols (GTP) and its ma... BeFree,GAD 24481780 Detail
0.034 Malignant neoplasm of breast These findings indicate that GALNT14 contributes to breast cancer invasion by al... BeFree,GAD 24962947 Detail
0.034 Malignant neoplasm of breast Lack of association between the matrix metalloproteinase-2 -1306C>T polymorphism... BeFree,GAD 24998547 Detail
0.034 Malignant neoplasm of breast It has been reported that COX-2 expression is associated with MMP-2 expression i... BeFree,GAD 24998576 Detail
0.034 Malignant neoplasm of breast The his6-rTIMP-1 was bioactive as shown by its proper inhibitory effect on MMP-2... BeFree,GAD 24998777 Detail
0.034 Malignant neoplasm of breast It is known that fibronectin is capable of promoting the expression of MMP-2 in ... BeFree,GAD 25208219 Detail
0.034 Malignant neoplasm of breast Gene expression data in stromal cells of human breast cancers reveal that MMP2 e... BeFree,GAD 25469981 Detail
0.034 Malignant neoplasm of breast Therefore, LASS2/TMSG1 may inhibit growth and invasion of breast cancer cell in ... BeFree,GAD 25501280 Detail
0.034 Malignant neoplasm of breast These results indicate that Ethyl gallate suppresses proliferation and invasion ... BeFree,GAD 25522911 Detail
0.034 Malignant neoplasm of breast Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloprote... BeFree,GAD 25656607 Detail
0.034 Malignant neoplasm of breast Matrix metalloproteinase-9 -1562T allele and its combination with MMP-2 -735 C a... BeFree,GAD 25735351 Detail
<0.001 Bronchial Neoplasms NA BeFree Detail
0.008 bronchopulmonary dysplasia NA GAD,LHGDN Detail
0.120 calcinosis NA CTD_human Detail
<0.001 Carcinoid Tumor NA BeFree Detail
0.007 Malignant tumor of colon Here we report that forced GRP78 expression promotes colon cancer cell migration... BeFree 24314144 Detail
0.007 Malignant tumor of colon The frequency of individuals with MMP2 polymorphisms in colon cancer patients wa... BeFree 24998576 Detail
0.007 Malignant tumor of colon Reduced HP1β expression correlates with the increased level of pro- and active-M... BeFree 25201136 Detail
0.007 Malignant tumor of colon Functional analysis of cellular proliferative activities, by MTT assay, and inva... BeFree 25216407 Detail
0.007 Malignant tumor of colon Secernin-1 contributes to colon cancer progression through enhancing matrix meta... BeFree 25814779 Detail
0.001 Malignant neoplasm of endometrium The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid... BeFree 25308734 Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
0.010 Non-small cell lung carcinoma Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value... BeFree,GAD,LHGDN 25337249 Detail
0.010 Non-small cell lung carcinoma GOLPH3 overexpression is closely correlated with poor prognosis in human non-sma... BeFree,GAD,LHGDN 25659977 Detail
0.010 Non-small cell lung carcinoma The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome o... BeFree,GAD,LHGDN 25975224 Detail
0.007 renal cell carcinoma NA BeFree,LHGDN Detail
Annotation

Annotations

DescrptionSourceLinks
Determinations of the mRNA levels, real-time polymerase chain reaction and promoter assays were cond... DisGeNET Detail
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In this study, the possible association between MMP-9 and MMP-2 functional promoter polymorphism, st... DisGeNET Detail
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Stroma cell induced transcription of matrix metalloprotease 1 (MMP1) and matrix metalloprotease 2 (M... DisGeNET Detail
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The results generated by this study may have important clinical significance in the treatment of pat... DisGeNET Detail
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Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer ... DisGeNET Detail
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Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A Meta-Analysis. DisGeNET Detail
Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A Meta-Analysis. DisGeNET Detail
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The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... DisGeNET Detail
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At baseline, there were no effects of diabetes on MMP or TIMP mRNA or protein. mRNA and protein resp... DisGeNET Detail
At baseline, there were no effects of diabetes on MMP or TIMP mRNA or protein. mRNA and protein resp... DisGeNET Detail
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At baseline, there were no effects of diabetes on MMP or TIMP mRNA or protein. mRNA and protein resp... DisGeNET Detail
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Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloprot... DisGeNET Detail
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Our experimental data demonstrated that these two microRNAs inhibited the translation of mRNA of MT1... DisGeNET Detail
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Interplay of VEGFa and MMP2 regulates invasion of glioblastoma. DisGeNET Detail
A significant decline of MMP-9 and MMP-2 secretion in cultured U87MG was detected after incubation w... DisGeNET Detail
Our experimental data demonstrated that these two microRNAs inhibited the translation of mRNA of MT1... DisGeNET Detail
These results suggest that Ryk is important for the Wnt-5a-dependent induction of MMP-2 and invasive... DisGeNET Detail
In conclusion, our data suggest that SERPINB1 negatively regulates glioma cell migration and invasio... DisGeNET Detail
Moreover, knockdown of HIWI inhibited the migration and invasion of glioma cells by reducing the exp... DisGeNET Detail
Knockdown of miR-155 enhanced the anticancer effect of TMZ on glioma by targeting the MAPK13 and MAP... DisGeNET Detail
Silencing of the tumor suppressor gene WNK2 is associated with upregulation of MMP2 and JNK in gliom... DisGeNET Detail
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In this study, the possible association between MMP-9 and MMP-2 functional promoter polymorphism, st... DisGeNET Detail
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The spread and metastases of ATL as well as other tumors has been associated with matrix metalloprot... DisGeNET Detail
The spread and metastases of ATL as well as other tumors has been associated with matrix metalloprot... DisGeNET Detail
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We also investigated the relationship of MMP-2/-9 and TIMP-1/-2 expression at both the protein and g... DisGeNET Detail
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In this regard, the aim of the present study was to evaluate and compare sputum matrix metalloprotei... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In this study, the possible association between MMP-9 and MMP-2 functional promoter polymorphism, st... DisGeNET Detail
In this study, the possible association between MMP-9 and MMP-2 functional promoter polymorphism, st... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Pretreatment with helenalin, a nuclear factor-κB (NF-κB) inhibitor, was proved to abolish the promot... DisGeNET Detail
MiR-29s (miR-29a, miR-29b and miR-29c) had been approved that they decreased in gastric cancers (GC)... DisGeNET Detail
Combined treatment with p38 activator partially blocked the antimetastatic effects of baicalein, whi... DisGeNET Detail
Functional analysis studies revealed that ectopic expression of miR-133a reduced cell proliferation ... DisGeNET Detail
WISP-2 suppressed GC cell metastasis through reversing EMT and suppressing the expression and activi... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasio... DisGeNET Detail
The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlation with clinic-patho... DisGeNET Detail
Cleaved CD147 shed from the surface of malignant melanoma cells activates MMP2 produced by fibroblas... DisGeNET Detail
Induction of MDA-9/syntenin in melanoma was found to occur in a thrombin-independent signaling pathw... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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This correlated with reduced expression of the Erk target gene Zeb1 and the Zeb1 target gene MMP-2 i... DisGeNET Detail
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NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenuation of epithelial-m... DisGeNET Detail
These findings provide a mechanistic explanation for human studies linking increases in HSP27 and MM... DisGeNET Detail
This study aims to investigate the impacts of CO2 pneumoperitoneum on the growth of ovarian cancer i... DisGeNET Detail
Restoration of TFPI-2 counteracted the invasiveness of OSCC by inhibiting the enzymatic activity of ... DisGeNET Detail
The spread and metastases of ATL as well as other tumors has been associated with matrix metalloprot... DisGeNET Detail
HP1β suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2... DisGeNET Detail
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of exper... DisGeNET Detail
Our experimental results suggest that HCS has some anti-metastasis potential to suppress the growth ... DisGeNET Detail
Systemic delivery of protein nanocages bearing CTT peptides for enhanced imaging of MMP-2 expression... DisGeNET Detail
The inverse correlation of MMP-2 and miR-328 was also observed in tumor specimens, and MMP-2 express... DisGeNET Detail
Mechanism dissection found that knocking-down TR4 in PCa cells suppressed metastasis-related genes i... DisGeNET Detail
GOLPH3 overexpression is closely correlated with poor prognosis in human non-small cell lung cancer ... DisGeNET Detail
Resistant cells expressed higher levels of genes coding for cancer stem cell markers (JARID1B, CD271... DisGeNET Detail
Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nude mouse orthotopic i... DisGeNET Detail
The present study demonstrated that GRP78 plays important roles in invasion and metastasis of ESCC, ... DisGeNET Detail
WISP-2 suppressed GC cell metastasis through reversing EMT and suppressing the expression and activi... DisGeNET Detail
Multidimensional reduction analysis revealed LXR-β (rs3546355 G &gt; A, rs2695121 T &gt; C), MMP-2 (... DisGeNET Detail
Multidimensional reduction analysis revealed LXR-β (rs3546355 G &gt; A, rs2695121 T &gt; C), MMP-2 (... DisGeNET Detail
In addition, TLX is coexpressed with the migratory neural progenitor markers CD15 and matrix metallo... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MMP-2 -1575G/A polymorphism modifies the onset of optic neuritis as a first presenting symptom in MS... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Furthermore, we determine the functional relevance of Beclin-1 knockdown to osteosarcoma cell growth... DisGeNET Detail
Furthermore, miR-142 inhibited osteosarcoma cell invasion by inducing E-cadherin expression and redu... DisGeNET Detail
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-med... DisGeNET Detail
Questions about XY Wen et al. entitled Matrix metalloproteinase 2 expression and survival of patient... DisGeNET Detail
NA DisGeNET Detail
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the... DisGeNET Detail
Matrix metalloproteinase-2 (MMP-2) is closely related to the pathogenesis of ovarian cancer. DisGeNET Detail
Our previous study indicated that BCL2-associated athanogene 3 (BAG3) enhances matrix metalloprotein... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In contrast to NM23-H1, MMP-2 expression was significantly higher in CO2 pneumoperitoneum groups tha... DisGeNET Detail
NA DisGeNET Detail
No statistically significant differences were detected between patient (ET+PV) and control groups re... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: Prognostic biological... DisGeNET Detail
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NA DisGeNET Detail
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However, the mean scores for MMP-2 stain intensity and proportion were significantly higher in malig... DisGeNET Detail
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NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Furthermore, the loss of MMP2 activity suggests that fibrotic skin abnormalities in GAPO syndrome ar... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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No statistically significant differences were detected between patient (ET+PV) and control groups re... DisGeNET Detail
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NA DisGeNET Detail
NA DisGeNET Detail
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NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloprot... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Norcantharidin enhances TIMP‑2 anti‑vasculogenic mimicry activity for human gallbladder cancers thro... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
There was a significant upregulation of the mRNA expression of matrix metalloproteinase-2 (MMP2) and... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Several polymorphisms within the MMP2 promoter region have been reported in cases with oncogenesis a... DisGeNET Detail
Matrix metalloproteinase-2 (MMP-2) is involved in degradation of extra-cellular matrix proteins and ... DisGeNET Detail
Overall, our results reveal a previously undefined role for MMP2 in metastatic outgrowth mediated by... DisGeNET Detail
Experiments in vitro validated that SCRN1 may promote cancer cell proliferation and secretion of mat... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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Our aim in the present study was to examine the relationships among BAG3, miR-29b and MMP2 in endome... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The effects of epigallocatechingallate (EGCG) on the migration and expression of MMP-2 of uveal mela... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Norcantharidin enhances TIMP‑2 anti‑vasculogenic mimicry activity for human gallbladder cancers thro... DisGeNET Detail
In conclusion, the present study reveals that the increased expression of OCT4 is correlated with th... DisGeNET Detail
Our results demonstrated that DAPK1 gene over-expression can suppress the proliferation, migration, ... DisGeNET Detail
Furthermore, we show that Nodal promotes pancreatic cancer cell migration and invasion, induces epit... DisGeNET Detail
Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nude mouse orthotopic i... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In liver fibrosis in both human and mouse tissue MMP expression and activity (MMP-2, -9, -13 and -14... DisGeNET Detail
NA DisGeNET Detail
Evaluation of matrix metalloproteinase-2 in lung cancer. DisGeNET Detail
The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenuation of epithelial-m... DisGeNET Detail
And the lung cancer metastasis factors (MMP-2, MMP-9, VEGF, and CXCR4) were decreased in miR-451 gro... DisGeNET Detail
PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activa... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In the direct anti-metastatic action, antrodan (30-70 μg/mL) was found to significantly inhibit inva... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Matrix metalloproteinase-2 family member expression, a key pathway in osteosarcoma metastatic capaci... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In conclusion, this study showed that the MMP2 -1306 TT and MMP9 -1562 CC genotypes were associated ... DisGeNET Detail
The present study demonstrated that GRP78 plays important roles in invasion and metastasis of ESCC, ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Stroma cell induced transcription of matrix metalloprotease 1 (MMP1) and matrix metalloprotease 2 (M... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Increased expression of p21-activated kinase 4 in adenomyosis and its regulation of matrix metallopr... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In conclusion, the present study reveals that the increased expression of OCT4 is correlated with th... DisGeNET Detail
Furthermore, we show that Nodal promotes pancreatic cancer cell migration and invasion, induces epit... DisGeNET Detail
Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nude mouse orthotopic i... DisGeNET Detail
Matrix metalloproteinase 2 (MMP-2) in metastatic cancer tissue, which is associated with a poor prog... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MiR-130b suppresses prostate cancer metastasis through down-regulation of MMP2. DisGeNET Detail
Our data showed that knockdown of SPAG9 in prostate cancer cell lines inhibited cell motility and in... DisGeNET Detail
Adipocyte-derived monocyte chemotactic protein-1 (MCP-1) promotes prostate cancer progression throug... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Furthermore, the loss of MMP2 activity suggests that fibrotic skin abnormalities in GAPO syndrome ar... DisGeNET Detail
NA DisGeNET Detail
In this study, the possible association between MMP-9 and MMP-2 functional promoter polymorphism, st... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid receptors expressio... DisGeNET Detail
Our experimental results suggest that HCS has some anti-metastasis potential to suppress the growth ... DisGeNET Detail
Overexpression of miR-29c suppresses pancreatic cancer liver metastasis in a nude mouse orthotopic i... DisGeNET Detail
NA DisGeNET Detail
Functional polymorphisms in the promoter region of MMP-2 and MMP-9 and susceptibility to obstructive... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloprot... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Moreover, the suppressive role of miR-199a in cell migration in cSCC cells was also associated with ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Furthermore, we determine the functional relevance of Beclin-1 knockdown to osteosarcoma cell growth... DisGeNET Detail
Furthermore, miR-142 inhibited osteosarcoma cell invasion by inducing E-cadherin expression and redu... DisGeNET Detail
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-med... DisGeNET Detail
Questions about XY Wen et al. entitled Matrix metalloproteinase 2 expression and survival of patient... DisGeNET Detail
NA DisGeNET Detail
While MMP-2 and uPA have been demonstrated to be important mediators of EMMPRIN signaling, the role ... DisGeNET Detail
Several polymorphisms within the MMP2 promoter region have been reported in cases with oncogenesis a... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MMP-2 -735C/T and MMP-12 357Asn/Ser polymorphisms are not related to GAgP. DisGeNET Detail
MiR-130b suppresses prostate cancer metastasis through down-regulation of MMP2. DisGeNET Detail
Our data showed that knockdown of SPAG9 in prostate cancer cell lines inhibited cell motility and in... DisGeNET Detail
Adipocyte-derived monocyte chemotactic protein-1 (MCP-1) promotes prostate cancer progression throug... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In the present study, we demonstrate that green tea polyphenols (GTP) and its major constituent, epi... DisGeNET Detail
These findings indicate that GALNT14 contributes to breast cancer invasion by altering the cell prol... DisGeNET Detail
Lack of association between the matrix metalloproteinase-2 -1306C>T polymorphism and breast cancer s... DisGeNET Detail
It has been reported that COX-2 expression is associated with MMP-2 expression in thyroid and breast... DisGeNET Detail
The his6-rTIMP-1 was bioactive as shown by its proper inhibitory effect on MMP-2 activity, and its s... DisGeNET Detail
It is known that fibronectin is capable of promoting the expression of MMP-2 in MCF7 breast cancer c... DisGeNET Detail
Gene expression data in stromal cells of human breast cancers reveal that MMP2 expression is also po... DisGeNET Detail
Therefore, LASS2/TMSG1 may inhibit growth and invasion of breast cancer cell in vitro through decrea... DisGeNET Detail
These results indicate that Ethyl gallate suppresses proliferation and invasion in human breast canc... DisGeNET Detail
Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibit... DisGeNET Detail
Matrix metalloproteinase-9 -1562T allele and its combination with MMP-2 -735 C allele are risk facto... DisGeNET Detail
Evaluation of matrix metalloproteinase-2 in lung cancer. DisGeNET Detail
The rVP1-mediated downregulation of COX-2/PGE2 and MIG-7 led to not only attenuation of epithelial-m... DisGeNET Detail
And the lung cancer metastasis factors (MMP-2, MMP-9, VEGF, and CXCR4) were decreased in miR-451 gro... DisGeNET Detail
These results suggested that PFIO could suppress the invasion and migration of human lung carcinoma ... DisGeNET Detail
PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activa... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Functional analysis of cellular proliferative activities, by MTT assay, and invasive potential, by T... DisGeNET Detail
NA DisGeNET Detail
Here we report that forced GRP78 expression promotes colon cancer cell migration and invasion throug... DisGeNET Detail
The frequency of individuals with MMP2 polymorphisms in colon cancer patients was higher than indivi... DisGeNET Detail
Reduced HP1β expression correlates with the increased level of pro- and active-MMP2 in colon cancer ... DisGeNET Detail
Functional analysis of cellular proliferative activities, by MTT assay, and invasive potential, by T... DisGeNET Detail
Secernin-1 contributes to colon cancer progression through enhancing matrix metalloproteinase-2/9 ex... DisGeNET Detail
Pretreatment with helenalin, a nuclear factor-κB (NF-κB) inhibitor, was proved to abolish the promot... DisGeNET Detail
MiR-29s (miR-29a, miR-29b and miR-29c) had been approved that they decreased in gastric cancers (GC)... DisGeNET Detail
Combined treatment with p38 activator partially blocked the antimetastatic effects of baicalein, whi... DisGeNET Detail
Functional analysis studies revealed that ectopic expression of miR-133a reduced cell proliferation ... DisGeNET Detail
WISP-2 suppressed GC cell metastasis through reversing EMT and suppressing the expression and activi... DisGeNET Detail
Extra virgin olive oil phenols suppress migration and invasion of T24 human bladder cancer cells thr... DisGeNET Detail
In conclusion, the findings of the present study show that naringenin is capable of inhibiting bladd... DisGeNET Detail
In addition, TLX is coexpressed with the migratory neural progenitor markers CD15 and matrix metallo... DisGeNET Detail
NA DisGeNET Detail
Interestingly, IR treatment leads to inhibition of matrix metalloproteinase-2 (MMP-2) activity and r... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the... DisGeNET Detail
Matrix metalloproteinase-2 (MMP-2) is closely related to the pathogenesis of ovarian cancer. DisGeNET Detail
Our previous study indicated that BCL2-associated athanogene 3 (BAG3) enhances matrix metalloprotein... DisGeNET Detail
Orthotopic tongue HNSCC xenografts showed excellent ratiometric fluorescent labeling with MMP2/9-cle... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Interestingly, IR treatment leads to inhibition of matrix metalloproteinase-2 (MMP-2) activity and r... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Both in vitro and in vivo assays indicated that ablation of endogenous EIF5A2 inhibited tumor angiog... DisGeNET Detail
NA DisGeNET Detail
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our aim in the present study was to examine the relationships among BAG3, miR-29b and MMP2 in endome... DisGeNET Detail
A significant decline of MMP-9 and MMP-2 secretion in cultured U87MG was detected after incubation w... DisGeNET Detail
Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Functional characterisation of a novel mutation affecting the catalytic domain of MMP2 in siblings w... DisGeNET Detail
NA DisGeNET Detail
The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid receptors expressio... DisGeNET Detail
Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A Meta-Analysis. DisGeNET Detail
NA DisGeNET Detail
Silencing alpha-fetoprotein inhibits VEGF and MMP-2/9 production in human hepatocellular carcinoma c... DisGeNET Detail
We also investigated the relationship of MMP-2/-9 and TIMP-1/-2 expression at both the protein and g... DisGeNET Detail
Reduction in HCC cell migration and invasion is also evident through reversal of EMT by increases E-... DisGeNET Detail
Mechanistic investigations showed that CYP3A5 overexpression limited MMP2/9 function and suppressed ... DisGeNET Detail
In our study, we tested a matrix metalloproteinase-2 (MPP2) aCPP in delivering hTERT siRNA into hepa... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The expressions of WNT5A and EMT related factors matrix metalloproteinase-2 of the WNT5A transferred... DisGeNET Detail
The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In AC MMP2 had a worsening impact on survival (P = 0.021) and it had independent prognostic value (P... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cultured AVMECs expressed higher angiogenic factors (VEGF, MMP-2) than the controlled BECs, implicat... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Extra virgin olive oil phenols suppress migration and invasion of T24 human bladder cancer cells thr... DisGeNET Detail
In conclusion, the findings of the present study show that naringenin is capable of inhibiting bladd... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Serum levels of RANK, OPG, IL-8, IL-6, and the OPG/sRANKL ratio were significantly higher, while the... DisGeNET Detail
NA DisGeNET Detail
In the present study, we demonstrate that green tea polyphenols (GTP) and its major constituent, epi... DisGeNET Detail
These findings indicate that GALNT14 contributes to breast cancer invasion by altering the cell prol... DisGeNET Detail
Lack of association between the matrix metalloproteinase-2 -1306C>T polymorphism and breast cancer s... DisGeNET Detail
It has been reported that COX-2 expression is associated with MMP-2 expression in thyroid and breast... DisGeNET Detail
The his6-rTIMP-1 was bioactive as shown by its proper inhibitory effect on MMP-2 activity, and its s... DisGeNET Detail
It is known that fibronectin is capable of promoting the expression of MMP-2 in MCF7 breast cancer c... DisGeNET Detail
Gene expression data in stromal cells of human breast cancers reveal that MMP2 expression is also po... DisGeNET Detail
Therefore, LASS2/TMSG1 may inhibit growth and invasion of breast cancer cell in vitro through decrea... DisGeNET Detail
These results indicate that Ethyl gallate suppresses proliferation and invasion in human breast canc... DisGeNET Detail
Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibit... DisGeNET Detail
Matrix metalloproteinase-9 -1562T allele and its combination with MMP-2 -735 C allele are risk facto... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Here we report that forced GRP78 expression promotes colon cancer cell migration and invasion throug... DisGeNET Detail
The frequency of individuals with MMP2 polymorphisms in colon cancer patients was higher than indivi... DisGeNET Detail
Reduced HP1β expression correlates with the increased level of pro- and active-MMP2 in colon cancer ... DisGeNET Detail
Functional analysis of cellular proliferative activities, by MTT assay, and invasive potential, by T... DisGeNET Detail
Secernin-1 contributes to colon cancer progression through enhancing matrix metalloproteinase-2/9 ex... DisGeNET Detail
The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid receptors expressio... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Correlations of lysyl oxidase with MMP2/MMP9 expression and its prognostic value in non-small cell l... DisGeNET Detail
GOLPH3 overexpression is closely correlated with poor prognosis in human non-small cell lung cancer ... DisGeNET Detail
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inop... DisGeNET Detail
NA DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs3546355 dbSNP
Genome
hg19
Position
chr16:55,423,612-55,540,603
Variant Type
snv
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