proliferative diabetic retinopathy
Information
- Disease name
- proliferative diabetic retinopathy
- Disease ID
- DOID:13207
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05393284 | Active, not recruiting | Phase 2 | Phase 2 Spectra Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy | August 16, 2022 | August 2024 |
| NCT04380077 | Active, not recruiting | N/A | Gas Tamponade for Prevention of Postoperative Vitreous Hemorrhage in Diabetics | May 15, 2020 | January 21, 2025 |
| NCT04278417 | Active, not recruiting | Phase 3 | Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy | November 19, 2020 | August 20, 2024 |
| NCT00529594 | Completed | N/A | Analgesic Effect of Etoricoxib (ARCOXIA®) 120MG During Retinal Laser Photocoagulation | August 2006 | November 2006 |
| NCT00545870 | Completed | Phase 3 | Bevacizumab Versus Ranibizumab for Diabetic Retinopathy | June 2008 | April 2013 |
| NCT03490318 | Completed | Effectiveness of Multimodal Imaging for the Evaluation of Retinal Oedema And New vesseLs in Diabetic Retinopathy | October 26, 2017 | December 23, 2019 | |
| NCT00445003 | Completed | Phase 3 | Laser-Ranibizumab-Triamcinolone for Proliferative Diabetic Retinopathy | March 2007 | July 2010 |
| NCT00446381 | Completed | N/A | Effect of Macugen(Pegaptanib)on Surgical Outcomes and VEGF Levels in Diabetic Patients With PDR (Diabetic Retinopathy or CSDME (Macular Edema) | October 2006 | September 2008 |
| NCT01025934 | Completed | Phase 4 | Intravitreal Bevacizumab for Surgical Treatment of Severe Proliferative Diabetic Retinopathy | ||
| NCT01041690 | Completed | N/A | Efficacy of PreOperative Bevacizumab for Diabetic Eye Disease | June 2007 | June 2008 |
| NCT01069341 | Completed | Phase 1 | Use of Ranibizumab to Treat Rubeosis in Diabetics Prior to Cataract Surgery | July 2007 | January 2012 |
| NCT01307072 | Completed | Compliance to Ophthalmic Follow-up Examinations and Surgical Outcome for Proliferative Diabetic Retinopathy | September 2008 | April 2010 | |
| NCT01383772 | Completed | N/A | Retinal Laser by Multi-spot Photocoagulator and Driving Eligibility | June 2012 | December 2014 |
| NCT01478737 | Completed | Phase 2 | Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy | November 2011 | April 2016 |
| NCT01478763 | Completed | Vitrous Analysis in Proliferative Diabetic Retinopathy | January 2011 | September 2014 | |
| NCT01489189 | Completed | Phase 3 | Prompt Panretinal Photocoagulation Versus Ranibizumab+Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy | March 2012 | February 5, 2018 |
| NCT01535495 | Completed | Phase 1 | Propranolol for Diabetic Retinopathy | February 2012 | December 2015 |
| NCT01571232 | Completed | Phase 2 | Ozurdex for Treatment of Recalcitrant Diabetic Macular Edema | April 2012 | March 2015 |
| NCT01627977 | Completed | Phase 3 | Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy | October 2012 | March 2014 |
| NCT01724385 | Completed | Phase 4 | Intravitreal Bevacizumab for Proliferative Diabetic Retinopathy | August 2012 | December 2012 |
| NCT01724554 | Completed | Phase 1/Phase 2 | Impact of Intravitreal Aflibercept Injections on Capillary Non-Perfusion | November 2012 | October 2014 |
| NCT01758757 | Completed | N/A | Comparison of Small-gauge Vitrectomy and Conventional Vitrectomy for Proliferative Diabetic Retinopathy | September 2007 | July 2011 |
| NCT01813773 | Completed | Phase 2/Phase 3 | Treatment With Intravitreal Aflibercept Injection For Proliferative Diabetic Retinopathy, The A.C.T Study | March 2013 | April 2016 |
| NCT01854593 | Completed | Phase 4 | Prospective Randomized Controlled Study of Intravitreal Injection of Bevacizumab for Proliferative Diabetic Retinopathy | May 2012 | March 2014 |
| NCT01920984 | Completed | N/A | Vitreous Levels of Cysteine-rich 61 in Patients With Proliferative Diabetic Retinopathy | January 2005 | December 2006 |
| NCT01928550 | Completed | Diabetes PRP and OCT | August 2013 | May 25, 2016 | |
| NCT02096874 | Completed | Phase 4 | Bevacizumab and Peripheral Retinal Changes on Wide Field Angiography in Diabetic Macular Edema | June 2013 | June 2015 |
| NCT02157350 | Completed | Phase 3 | The Individually Marked Panretinal lasEr phoTokoagUlation for Proliferative Diabetic Retinopathy Study - DETECT | August 2014 | September 30, 2017 |
| NCT02464800 | Completed | Efficacy of Higher Cutting Rate in Microincision Vitrectomy for Proliferative Diabetic Retinopathy | April 2007 | March 2015 | |
| NCT02705274 | Completed | Phase 2/Phase 3 | PRP vs Bevacizumab for PDR Treatment | February 2016 | May 2017 |
| NCT02753400 | Completed | Phase 2 | Study to Evaluate Effects of Emixustat Hydrochloride in Subjects With Proliferative Diabetic Retinopathy | May 2016 | December 2017 |
| NCT02816710 | Completed | Phase 4 | Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy | July 2016 | September 2017 |
| NCT02857491 | Completed | N/A | Intravitreal Injection of Ranibizumab Versus Sham Before Vitrectomy in Patients With Proliferative Diabetic Retinopathy | July 2014 | September 30, 2017 |
| NCT02858076 | Completed | Phase 2/Phase 3 | Anti-VEGF vs. Prompt Vitrectomy for VH From PDR | November 2016 | January 2020 |
| NCT02863354 | Completed | Phase 2 | Intravitreal Aflibercept for Retinal Non-Perfusion in Proliferative Diabetic Retinopathy | August 2016 | May 2019 |
| NCT02879422 | Completed | N/A | Genetic Markers and Proliferative Diabetic Retinopathy | October 16, 2013 | January 2021 |
| NCT03113006 | Completed | N/A | The Individually-Marked Panretinal Laser phoTocoagulation for Proliferative Diabetic Retinopathy Study (TREAT) | May 1, 2017 | August 27, 2019 |
| NCT03522311 | Completed | Surgical Outcomes for Proliferative Diabetic Retinopathy by Preoperative Glycemic Control and Renal Function | January 2013 | October 2016 | |
| NCT03525899 | Completed | Macular Hole After Diabetic Vitrectomy | November 1, 2017 | December 1, 2017 | |
| NCT04285151 | Completed | N/A | Nd:YAG Laser Hyaloidotomy for Premacular Hemorrhage in Diabetic Eyes | January 2015 | January 2020 |
| NCT04674254 | Completed | Phase 4 | Macular Perfusion Changes After Anti-VEGF Versus Targeted Retinal Photocoagulation in Proliferative Diabetic Retinopathy | March 30, 2021 | March 15, 2023 |
| NCT05156021 | Completed | N/A | A Study on the Treatment Strategy of NVG Secondary to PDR | December 12, 2021 | December 31, 2022 |
| NCT05408416 | Completed | N/A | Comparison of Surgery Outcome Between Preoperative IVR and Intraoperative IVR in PPV for PDR | September 1, 2021 | May 29, 2022 |
| NCT05414149 | Completed | N/A | Efficacy and Safety Comparison of IVR and IVC Before Vitrectomy in Proliferative Diabetic Retinopathy | September 1, 2021 | May 31, 2022 |
| NCT05446948 | Completed | N/A | Observation of the Efficacy of Different Vitrectomy Systems to Treat Proliferative Diabetic Retinopathy | July 11, 2022 | June 1, 2023 |
| NCT05478967 | Completed | N/A | The Effect of IVA for Preventing Postvitrectomy Hemorrhage in PDR | August 8, 2019 | February 20, 2021 |
| NCT05677685 | Completed | N/A | VISUPRIME® Eye Drops | June 22, 2023 | January 23, 2024 |
| NCT00596505 | Completed | Intravitreal Bevacizumab Pretreatment for Reducing Preretinal Hemorrhage in Diabetic Vitrectomy | April 2007 | December 2007 | |
| NCT00606138 | Completed | Phase 1/Phase 2 | Ranibizumab for Treatment of Persistent Diabetic Neovascularization Assessed by Wide-Field Imaging | January 2008 | October 2010 |
| NCT00656435 | Completed | Phase 3 | Bevacizumab and Long Acting Gas in Diabetic Vitrectomy | December 2006 | February 2008 |
| NCT00682240 | Completed | Phase 4 | Morphological and Functional Retinal Changes Following Retinal Photocoagulation | October 2007 | February 2014 |
| NCT00728598 | Completed | Fractalkine, a CX3C Chemokine, Act as a Mediator of Ocular Angiogenesis | January 1998 | December 1998 | |
| NCT00737022 | Completed | Macular Appearance After Diabetic Vitrectomy | May 2005 | December 2006 | |
| NCT00737074 | Completed | Macular Hole in Diabetic Retinopathy | January 2002 | December 2007 | |
| NCT00745498 | Completed | N/A | Pre- and Intra-operative Intravitreal Bevacizumab Injection in Diabetic Vitrectomy | June 2008 | October 2010 |
| NCT00776763 | Completed | Phase 2 | Ocular Growth Factors Profile in Proliferative Retinopathies Before and After Intravitreal Bevacizumab | October 2008 | December 2010 |
| NCT00907114 | Completed | Phase 2 | Topic Ketorolac Added to Panphotocoagulation in Proliferative Diabetic Retinopathy | June 2009 | March 2015 |
| NCT00996437 | Completed | Phase 2/Phase 3 | Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (N) | June 2010 | January 2013 |
| NCT05938491 | Not yet recruiting | OCT and OCT-A Afer Diabetic Vitrectomy in PDR | August 1, 2023 | January 1, 2025 | |
| NCT05514925 | Recruiting | Phase 4 | Cryoapplication Versus Anti-VEGF Before Diabetic Vitrectomy | November 21, 2017 | December 31, 2022 |
| NCT05631054 | Recruiting | Establishment and Validation of a Risk Prediction Model for Long-term Low Vision After Vitrectomy in PDR Patients | November 10, 2022 | June 30, 2023 | |
| NCT05642793 | Recruiting | Phase 2 | Effect of Postvitrectomy Proactive Use of Conbercept on Postoperative Complications in PDR Patients | April 1, 2022 | March 1, 2024 |
| NCT05169502 | Recruiting | Discovering Early Biomarkers in Circulating Endothelial Cells for Diabetes Complications by Single Cell RNA Sequencing | December 8, 2021 | December 31, 2023 | |
| NCT00563043 | Terminated | Phase 4 | Changes in Electroretinogram and Contrast Sensitivity After PASCAL Treatment | October 2007 | February 2008 |
| NCT01737957 | Terminated | N/A | Safety and Efficacy of Low-Fluence PRP for PDR | November 2012 | March 2013 |
| NCT01589029 | Terminated | Phase 1 | A Pilot Study on the Effects of ILARIS® on Patients With Proliferative Diabetic Retinopathy (PDRP) | April 2012 | November 2014 |
| NCT00802269 | Terminated | Phase 4 | Pain Using Reduced Fluence Parameters in Photocoagulation for Diabetic Retinopathy. | March 2008 | November 2008 |
| NCT00563628 | Terminated | Phase 4 | Changes in Macular Thickness After Patterns Scan Laser | October 2007 | February 2008 |
| NCT00668785 | Terminated | Phase 2 | Intravitreal Ranibizumab to Treat Macular Edema After Panretinal Photocoagulation (Phase II) | March 2007 | March 2012 |
| NCT00600262 | Terminated | Phase 2/Phase 3 | Intravitreal Bevacizumab for Diabetic Retinopathy | December 2005 | June 2006 |
| NCT00170742 | Terminated | Phase 3 | Study to Assess the Efficacy and Safety of Monthly Octreotide Intramuscular Injections in Patients With Proliferative Diabetic Retinopathy After Lasercoagulation This Study is Not Being Conducted in the United States. | December 2003 | |
| NCT01044875 | Unknown status | N/A | Trial of Yellow 577 nm Laser Versus Green 532 nm Laser for Proliferative Diabetic Retinopathy | September 2009 | October 2011 |
| NCT02630277 | Unknown status | Phase 2 | Evaluation of Treatment of High riSk proLiferative Diabetic retinopathY With Intravitreal Aflibercept injectioN | January 2016 | June 2017 |
| NCT01312207 | Unknown status | Macular Tractional Retinoschisis in Proliferative Diabetic Retinopathy | February 2011 | February 2012 | |
| NCT01389505 | Unknown status | Phase 2 | Bevacizumab as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy | February 2011 | September 2012 |
| NCT00516464 | Unknown status | Phase 3 | Evaluation of Ranibizumab in Proliferative Diabetic Retinopathy (PDR) Requiring Vitrectomy | August 2007 | August 2008 |
| NCT04464694 | Unknown status | Phase 4 | Pre-vitrectomy Intravitreal Ranibizumab for Patients With Proliferative Diabetic Retinopathy Combined With Diabetic Macular Edema | September 1, 2020 | June 1, 2022 |
| NCT01486771 | Unknown status | Phase 4 | Macugen for Proliferative Diabetic Retinopathy Study With Extended Dosing (M-PDRS ED) | November 2007 | February 2014 |
| NCT04800679 | Unknown status | Phase 2 | Intravitreal Bevacizumab vs Laser vs Combination of Bevacizumab and Modified Laser in PDR | March 1, 2020 | December 2021 |
| NCT05222633 | Unknown status | Anti-VEGF in Real-world | January 1, 2022 | May 1, 2023 | |
| NCT01790945 | Unknown status | Diabetic Macular Edema and Diabetic Retinopathy Screening (TeleMed) With Automated Retinal Photography | February 2013 | August 2013 | |
| NCT03506750 | Unknown status | Phase 4 | Day Regimes of CONbercept on CytokinEs of PDR Patients Undergoing Vitrectomy - Trial (CONCEPT) | June 3, 2017 | December 31, 2018 |
| NCT00403026 | Unknown status | N/A | Intravitreal Bevacizumab for Retinal Disorders | August 2006 | November 2006 |
| NCT01921192 | Unknown status | Phase 4 | Effect of Folic Acid, Vitamin B6 and Vitamin B12 in Diabetic Retinopathy | September 2012 | |
| NCT01946451 | Unknown status | Gene Expression in Patients With Epiretinal Membranes | June 2012 | December 2013 | |
| NCT02005432 | Unknown status | Phase 4 | PASCAL Laser Versus ETDRS Laser Associated With Intravitreal Ranibizumab (IVR) Versus Only IVR for Proliferative Diabetic Retinopathy | February 2012 | |
| NCT02067013 | Unknown status | Phase 2 | Analysis of Aqueous and Vitreous Humor | July 2015 | July 2017 |
| NCT03609996 | Unknown status | Retrospective Review of Proliferative Diabetic Retinopathy Patients | June 1, 2018 | December 1, 2019 | |
| NCT00993525 | Unknown status | Phase 1/Phase 2 | Intravitreal Ranibizumab For Persistent New Vessels In Diabetic Retinopathy(Inipe Study) | September 2008 | March 2010 |
| NCT03633266 | Unknown status | N/A | Anti-VEGF Instead of Intraoperative PRP in Proliferative Diabetic Retinopathy | September 1, 2018 | December 1, 2022 |
| NCT02328118 | Unknown status | Phase 2/Phase 3 | 25-Gauge Vitrectomy With Ranibizumab or Triamcinolone Acetonide on Proliferative Diabetic Retinopathy in China | February 2015 | May 2017 |
| NCT02447185 | Unknown status | Phase 3 | 25-G Vitrectomy With Ranibizumab or Triamcinolone Acetonide on PDR in China-Randomized Clinical Trial | June 2015 | December 2021 |
| NCT02911311 | Unknown status | N/A | Conbercept vs Panretinal Photocoagulation for the Management of Proliferative Diabetic Retinopathy | October 12, 2019 | December 2022 |
| NCT02976012 | Unknown status | Phase 1/Phase 2 | Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH | June 2016 | June 2018 |
| NCT00600236 | Withdrawn | Phase 3 | HLA and it Relation With the Development of Proliferative Diabetic Retinopathy in Mexican Population | September 2004 | January 2008 |
| NCT01589718 | Withdrawn | Phase 3 | A Study of the Safety, Tolerability, and Efficacy of IVT Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Management of Tractional Retinal Detachment and Vitreous Hemorrhage With Proliferative Diabetic Retinopathy | April 2012 | March 2014 |
| NCT01568242 | Withdrawn | N/A | Changes in Vitreous Temperature During Phacoemulsification | February 2012 | May 2012 |
- Disase is a (Disease Ontology)
- DOID:8947
- Cross Reference ID (Disease Ontology)
- ICD9CM:362.02
- Cross Reference ID (Disease Ontology)
- NCI:C84457
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154679002
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0154830
- Exact Synonym (Disease Ontology)
- PDR
- MedGen concept unique identifier (MedGen Concept name)
- C0154830
- MedGen unique identifier (MedGen Concept name)
- 56347