Annotation Detail

Information
Associated Genes
MMP2
Associated Variants
MMP2 MUTATION
MMP2 MUTATION
Associated Disease
stomach carcinoma
Source Database
DisGeNET
Description
Combined treatment with p38 activator partially blocked the antimetastatic effects of baicalein, while p38 inhibitor (SB203580) and baicalein resulted in a synergistic reduction in MMP-2 and -9 expression; the invasive ability of gastric cancer cells was also inhibited.
Pubmed
25502212
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00895758177865001
Drugs