Chronic heart failure

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Information
Disease name
Chronic heart failure
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
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Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06360315 Active, not recruiting N/A Impact of a Letter Encouraging Pneumococcal Vaccination on the 1-year Vaccination Rate in Heart Failure Patients With a Primary Care Physician January 2, 2023 June 2024
NCT05987267 Active, not recruiting N/A Nurse-led Multidisciplinary Precision Care for Patients With Chronic Heart Failure November 24, 2021 December 31, 2024
NCT04719637 Active, not recruiting N/A Clinical Study of an Ultrasound Renal Denervation System in Patients With Heart Failure August 24, 2021 November 2025
NCT04489355 Active, not recruiting The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy January 28, 2013 May 1, 2024
NCT03089034 Active, not recruiting Singapore Cohort of Patients With Advanced Heart Failure July 24, 2017 October 31, 2025
NCT03681210 Active, not recruiting Destination Therapy Post Approval Study October 31, 2018 April 2026
NCT05560737 Active, not recruiting ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients September 14, 2021 December 31, 2023
NCT05913778 Active, not recruiting N/A Long-tErm Effects of Enhanced eXternal CountErpuLsation December 10, 2020 December 10, 2024
NCT05377190 Active, not recruiting N/A Continuum: Digital Health to Manage Heart Failure Outpatients June 8, 2022 June 2024
NCT06393595 Active, not recruiting Prediction of Outcomes in Patients With Chronic Heart Failure Based on Tissue Raman Spectroscopy November 1, 2022 June 20, 2024
NCT04578353 Completed N/A Effect of Enhanced Sweat Rate on the Safety and Edema Status of Chronic Edematous Patients January 28, 2020 June 12, 2022
NCT04698954 Completed N/A Evaluating the Adherence Improving Self-Management Strategy Intervention in Chronic Heart Failure Patients December 14, 2020 February 24, 2023
NCT04699253 Completed Usability and Feasibility of a Personalized, Web-based Education and Self-management Approach for Patients With Chronic Heart Failure Across Four European Sites July 1, 2021 December 31, 2023
NCT04839211 Completed N/A Inspiratory Muscle Training in Heart Failure June 3, 2021 November 21, 2022
NCT04781881 Completed Special Drug Use Surveillance for Entresto Tablets March 4, 2021 April 21, 2023
NCT04793880 Completed N/A Cost and Shared Decision-Making for Heart Failure June 1, 2021 November 15, 2023
NCT00469001 Completed Evaluation of NT PRO BNP Guided Therapy on Hospitalization Rate and Mortality in Patients With Chronic HF NYHA II-IY June 2007 March 2010
NCT00477789 Completed Phase 4 Effects of Allopurinol on Diastolic Function in Chronic Heart Failure Patients
NCT00488410 Completed N/A SYNCHRO. Evaluation of the Forecasts Parameters of Real Time-three-dimensional Doppler Echocardiography in Selecting Patients With Chronic Heart Failure for Cardiac Resynchronisation Therapy November 2006 December 2009
NCT00501514 Completed Phase 3 Effects of Growth Hormone on Exercise Capacity November 1997 November 2005
NCT00078286 Completed Phase 2/Phase 3 Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure November 2003 September 2008
NCT00517426 Completed Phase 4 Effects of Acetazolamide and CO2 Inhalation on Exercise-induced Periodic Breathing in Heart Failure July 2007 August 2012
NCT00517725 Completed Phase 4 Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure July 2007 May 2010
NCT00520780 Completed Phase 3 Ferinject® Assessment in Patients With Iron Deficiency and Chronic Heart Failure (FAIR-HF) April 2007 September 2009
NCT00094562 Completed Phase 2 A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss June 2004 September 2007
NCT00543881 Completed Phase 3 Telemedical Interventional Monitoring in Heart Failure January 2008 October 2010
NCT00652652 Completed Phase 4 Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS March 2003 January 2004
NCT00654719 Completed Phase 2 Enteral Nutrition in Congestive Heart Failure and Cardiac Cachexia April 2001 February 2002
NCT00701285 Completed Phase 4 South Korean Pitavastatin Heart Failure Study July 2008 May 2014
NCT00130884 Completed Phase 2 Peroral Levosimendan in Chronic Heart Failure March 2005 March 2006
NCT00751972 Completed N/A Evaluation of the HeartWare Left Ventricular Assist Device for the Treatment of Advanced Heart Failure August 2008 August 2013
NCT00792402 Completed Computerized Guideline in Heart Failure: Implementation Process and Impact Evaluation November 2007 November 2011
NCT00149409 Completed Phase 2/Phase 3 Omega-3-Polyunsaturated Fatty-Acids (N3-Pufa) In Patients With Severe Chronic Heart Failure September 2005 February 2008
NCT00841139 Completed Phase 2 Metabolic Manipulation in Chronic Heart Failure February 2009 September 2011
NCT00852020 Completed N/A Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Chronic Heart Failure and Chronic Obstructive Pulmonary Disease Patients April 2009 April 2011
NCT00853658 Completed Phase 3 Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure March 2009 October 2015
NCT01115504 Completed Phase 3 Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy May 2010 December 2010
NCT04325594 Completed Phase 2 The Application of the Umbilical Cord Mesenchymal Stem Cells in the Complex Treatment of Non-ischemic Heart Failure March 1, 2020 April 1, 2023
NCT04352426 Completed Symptom-limited Stair Climbing Test in Heart Failure January 13, 2017 November 12, 2017
NCT04905433 Completed N/A The Need for Breathing Retraining: the Elephant in the Cardiac Rehabilitation Room June 1, 2019 March 1, 2020
NCT04871178 Completed N/A Dissertation Project Title: Effects of a Mindfulness-Based Intervention in Chronic Heart Failure October 10, 2010 December 31, 2013
NCT04515290 Completed Phase 2 A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease. May 7, 2020 April 22, 2022
NCT04516525 Completed The Impact of CRT on Renal Function April 15, 2016 August 6, 2020
NCT04549415 Completed Phase 4 The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes January 1, 2018 November 15, 2019
NCT04574050 Completed N/A SELF-BREATHE RCT for Chronic Breathlessness January 11, 2021 January 30, 2022
NCT04575428 Completed Phase 2 Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III) February 5, 2020 June 16, 2021
NCT02413151 Completed N/A Exercise Training Following Cardiac Resynchronization Therapy in Patients With Chronic Heart Failure January 2012 July 2015
NCT02441218 Completed Phase 3 Effects of Ivabradine on Cardiovascular Events in Patients With Moderate to Severe Chronic Heart Failure and Left Ventricular Systolic Dysfunction. A Three-year International Multicentre Study September 2006 April 2010
NCT02463786 Completed Improving Knowledge To Efficaciously RAise Level of Contemporary Treatment in Heart Failure ( July 1, 2012 June 30, 2017
NCT05613140 Completed Sacubitril/Valsartan Treated Adult Patients With Chronic Heart Failure August 2, 2021 November 5, 2021
NCT05538819 Completed The Effects of Glimepiride in Patients With Type 2 Diabetes and Chronic Heart Failure June 1, 2017 July 1, 2022
NCT02523560 Completed N/A Applying Telemedicine in a Model of Implementing Cardiac Rehabilitation in Heart Failure Patients June 2015 March 2018
NCT05480345 Completed N/A Significance of Impedance Cardiography and Early Repolarization Pattern in ECG in Congestive Heart Failure December 20, 2019 June 30, 2022
NCT02578225 Completed Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey October 2015 June 2017
NCT00057356 Completed Phase 2 Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure November 2002 March 2004
NCT02622412 Completed N/A Evaluation of a Multi-professional Breathlessness Service for Patients With Breathlessness Due to Any Advanced Disease March 2, 2015 April 30, 2019
NCT00012818 Completed N/A Efficacy and Cost Effectiveness of Relaxation and Response to CHF September 2003
NCT02642562 Completed Phase 4 Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN August 2016 August 26, 2022
NCT02725151 Completed Acute Heart Failure Monitoring Via Inferior Vena Cava Ultrasound August 2015 January 2017
NCT05364190 Completed Phase 3 Canagliflozin in Patients With Acute Decompansted Heart Failure June 4, 2022 December 1, 2023
NCT05332223 Completed The Epidemiology of Sleep Disordered Breathing in Patients With Congestive Heart Failure April 15, 2022 December 31, 2023
NCT02737995 Completed Phase 1 Iron Stores and Skeletal Muscle Metabolism in Chronic Heart Failure May 2015
NCT02790801 Completed The First Russian Observational Survey of Heart Failure Patients With Atrial Fibrillation February 2015 May 31, 2017
NCT02812797 Completed Prognostic Value of Adipokine Levels of Patients With Chronic Heart Failure June 2016 January 2020
NCT02814097 Completed Phase 2 A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction September 2, 2016 June 2, 2017
NCT05230927 Completed Cognitive Impairment, Frailty and Rehabilitative Outcome in Older Patients Affected by Cardiorespiratory Disease April 21, 2020 December 23, 2022
NCT02840565 Completed Phase 1 Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453 September 2007 July 2008
NCT02845037 Completed Phase 1 Tolerability, Pharmacokinetics and Dopamine ß-hydroxylase (DßH) Inhibition Profile of BIA 5-453 May 2007 September 2007
NCT02894580 Completed Primary Prevention of Sudden Cardiac Death (PREV-DEATH) January 2015 June 2015
NCT02898246 Completed Fear of Activity in Situations (FActS) - Study 2016 November 2016 July 2019
NCT02916160 Completed Phase 4 Sacubitril-valsartan and Heart Failure Patients : the ENTRESTO-SAS Study September 22, 2016 February 27, 2020
NCT02964650 Completed Phase 2 Optimising Pacemaker Therapy for Contractility June 20, 2017 October 31, 2019
NCT03037255 Completed Association of Long-term Conditions With Survival Following Heart Attack in England and Wales January 2003 January 2021
NCT05226416 Completed Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection February 21, 2022 April 21, 2023
NCT03090724 Completed Phase 1 Pharmacokinetics of BIA 5-453 and Its Metabolites June 13, 2008 August 12, 2008
NCT03106298 Completed Iron Deficiency and FGF23 Regulation in CKD and HF December 18, 2015 August 1, 2018
NCT03119298 Completed Measuring Fear of Physical Activity in Patients With Heart Failure May 2, 2017 December 16, 2019
NCT03126656 Completed Phase 4 Effects of Testosterone on Myocardial Repolarization September 2016 April 2017
NCT03128528 Completed Phase 2 Analysing the Effect of Empagliflozin on Reduction of Tissue Sodium Content in Patients With Chronic Heart Failure July 1, 2017 April 30, 2020
NCT05213546 Completed N/A Clinical Relevance of Different Training Intensities in Chronic Heart Failure. August 1, 2020 October 1, 2021
NCT05102903 Completed Phase 1 A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016A" With "BR1016B" in Healthy Volunteers October 22, 2021 December 14, 2021
NCT03320655 Completed N/A Effectiveness of Combined Aerobic and Strength Training in Acute and Chronic Adaptations in Patients With Heart Failure October 9, 2017 March 30, 2019
NCT05102266 Completed Phase 1 A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016C" With "BR1016D" in Healthy Volunteers October 27, 2021 December 18, 2021
NCT03342690 Completed Drug Use Investigation of Selara Tablets (an Investigation for Chronic Heart Failure) July 5, 2017 July 15, 2020
NCT03342833 Completed Phase 2 Blood Flow Restriction Training in Chronic Heart Failure: an Effective Training Strategy? March 10, 2018 April 1, 2021
NCT05089279 Completed Phase 1 Study to Evaluate the Safety and Pharmacokinetics of CKD-349 in Healthy Adult Volunteers November 3, 2021 April 6, 2022
NCT00417222 Completed Phase 3 Supplemental Benefit of Angiotensin Receptor Blocker in Hypertensive Patients With Stable Heart Failure Using Olmesartan November 2006 December 2013
NCT03597646 Completed N/A The Effect of Kinesio Taping on Pulmonary Function and Functional Capacity in Patients With Chronic Heart Failure September 8, 2016 February 10, 2017
NCT03603743 Completed N/A High Intensity Interval Training vs Moderate Intensity and Continuous Training in Chronic Heart Failure May 7, 2015 October 13, 2017
NCT03655925 Completed Human Leucocyte Antigen G and Chronic Heart Failure October 11, 2017 March 31, 2019
NCT03667989 Completed N/A SPECT-based Prediction and Evaluation of CRT Efficacy in CHF September 1, 2017 August 1, 2020
NCT03697980 Completed Apogee, A HeartWare HVAD Destination Product Surveillance Registry (PSR) Platform January 17, 2019 February 10, 2022
NCT03710057 Completed Effect of Ivabradine in Lowering Heart Rate and Quality of Life in Chronic Heart Failure Patients December 1, 2016 May 15, 2017
NCT03728075 Completed N/A Neuromuscular Electrical Stimulation in Chronic Heart Failure Patient January 21, 2017 March 29, 2017
NCT03803826 Completed N/A Cardiac Strains for Optimization of CRT in Non-Responders January 1, 2016 December 1, 2019
NCT04955405 Completed N/A The 7-Visit Transition of Care Hospital to Home Intervention: A Pilot Study January 31, 2022 October 31, 2023
NCT03845309 Completed N/A Nutritional Interventions in Chronic Heart Failure February 19, 2019 December 13, 2020
NCT03949309 Completed Pilot Study of ILIADE : Exploring Health Literacy Within Patients Hospitalized for Acute Cardiovascular Events June 24, 2019 December 12, 2019
NCT00437866 Completed Hepcidin in Anemic Chronic Heart Failure (CHF) Patients January 2007 July 2010
NCT04110431 Completed N/A Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy November 14, 2019 June 29, 2021
NCT00887588 Completed Phase 2 LCZ696 Compared to Valsartan in Patients With Chronic Heart Failure and Preserved Left-ventricular Ejection Fraction November 2009 December 2011
NCT00934609 Completed N/A Training Study to Evaluate the Benefit of Exercise for Patients With Chronic Heart Failure
NCT00984529 Completed Evaluation of Clinical Signs and Symptoms of Chronic Heart Failure in Patients Treated With Candesartan Cilexetil in Croatia September 2009 February 2010
NCT00997542 Completed Phase 4 Allopurinol in Chronic Heart Failure
NCT00032747 Completed Phase 2 Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT). August 2001 February 2003
NCT01092130 Completed Phase 2 Study to Investigate the Effects of Vitamin D Administration on Plasma Renin Activity in Patients With Stable Chronic Heart Failure March 2010 September 2012
NCT01104558 Completed Phase 4 Association Between Genetic Polymorphism of Beta-adrenergic Receptor and Effects of Bisoprolol in Korean Heart Failure Patients. December 2008 July 2010
NCT04143230 Completed N/A Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool May 23, 2017 October 15, 2019
NCT00214513 Completed Phase 3 A Randomized Trial of Effect of Low-Cost Maintenance Training on Exercise Capacity, Quality of Life and Morbidity June 2004 July 2006
NCT01166347 Completed N/A The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial August 2010 May 2017
NCT01181414 Completed Phase 4 Spanish Atrial Fibrillation And Resynchronization Study October 2010 January 2015
NCT01187823 Completed N/A The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients December 2010 March 2014
NCT06054048 Completed N/A Open Video System in Medicine (oVID) February 1, 2019 February 28, 2022
NCT00272805 Completed Phase 3 Drug Compliance and Quality of Life in Patients With Heart Failure Dosed With Either Once-daily or Twice-daily Coreg October 2005 July 2006
NCT01251406 Completed Phase 2 Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure January 2012 March 2014
NCT01292902 Completed N/A Regional Distribution of Ventilation in Patients With Chronic Heart Failure July 2010 December 2010
NCT01294111 Completed N/A Tai Chi Training for Elderly People With Chronic Heart Failure November 2010 May 2, 2018
NCT01304381 Completed N/A Integrated Cardiac Care and Palliative Homecare for Patients With Severe Heart Failure January 2011 April 2013
NCT01316432 Completed Phase 1 PK/PD Study of Subcutaneous Cenderitide Infusion in CHF Patients May 2011 November 2011
NCT01350310 Completed Phase 2 Safety and Efficacy Study of Intramyocardial Stem Cell Therapy in Patients With Dilated Cardiomyopathy March 2011 December 2014
NCT01365325 Completed N/A Handled Echocardiography and Chronic Heart Failure January 2009 December 2010
NCT01394562 Completed Phase 3 Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Iron Deficiency and Chronic Heart Failure July 2011 May 2016
NCT01408875 Completed N/A Cardiac Rehabilitation and Low Frequency Electrical MyoStimulation in Chronic Heart Failure October 2011 January 2014
NCT00288288 Completed Prospective Registry of Epicardial LV Leads Placed During Cardiac Surgery Procedures March 2006 May 2010
NCT01453608 Completed Phase 4 A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency October 2011 January 2015
NCT01472640 Completed N/A The Effect of Liraglutide on Left Ventricular Function in Chronic Heart Failure Patients With and Without Type 2 Diabetes Mellitus November 2011 October 2015
NCT00292162 Completed N/A Curing Atrial Fibrillation in Heart Failure January 2007 July 2009
NCT00294086 Completed Phase 2 A Study of Valsartan Administered Once Daily Versus Twice Daily, in Patients With Stable, Chronic Heart Failure December 2005 January 2007
NCT01548508 Completed N/A Evaluation of Functionnal ElectromyoStimulation on Leg In Advanced Chronic Heart Failure After Hospitalisation for Acute Decompensation July 2008 June 2014
NCT01576861 Completed Phase 2 Long-Term Efficacy and Safety of Growth Hormone Replacement Therapy in Chronic Heart Failure January 2007 December 2011
NCT01606553 Completed N/A Inspiratory Muscle Training in Patients With Chronic Heart Failure October 2010 June 2012
NCT01619891 Completed Phase 2 VitamIN D Treating patIents With Chronic heArT failurE August 2012 January 2016
NCT01690091 Completed Phase 2/Phase 3 Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes November 2012 December 2016
NCT01692119 Completed N/A Pharmacy-based Interdisciplinary Program for Patients With Chronic Heart Failure October 2012 March 2019
NCT00323973 Completed Phase 3 Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity July 2003 July 2006
NCT01739686 Completed N/A Collaborative Care to Alleviate Symptoms and Adjust to Illness in Chronic Heart Failure (CASA) Trial August 2012 December 2015
NCT01786512 Completed Phase 2 COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure February 26, 2013 August 19, 2015
NCT01787682 Completed N/A Nutritional and Functional Changes in Heart Failure and COPD December 2012 September 17, 2017
NCT00343902 Completed Phase 3 Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) Trial January 2000 May 2004
NCT01801722 Completed Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease April 2008 June 2008
NCT01804816 Completed N/A Acupuncture on Cardiac and Autonomic Function in Human Heart Failure February 2013 December 2021
NCT01813331 Completed ALERT-HF: Adherence to Guidelines in the Treatment of Patients With Chronic Heart Failure November 2012 February 2013
NCT01831128 Completed French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS) November 2009 September 2020
NCT01878630 Completed Phase 3 Telemedical Interventional Management in Heart Failure II August 8, 2013 May 17, 2018
NCT05904808 Completed Phase 4 The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study April 19, 2023 August 24, 2023
NCT00347087 Completed Phase 4 Effect of Irbesartan on Insulin Sensitivity in Chronic Heart Failure July 2004 June 2007
NCT01919918 Completed Phase 1 Muscle Afferent Feedback Effects in Patients With Heart Failure September 2013 January 3, 2018
NCT01939236 Completed Phase 2 Traditional Chinese Medicine for Treatment of Chronic Heart Failure May 2010 September 2012
NCT01966458 Completed N/A A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL) October 2013 August 2020
NCT01982292 Completed Phase 2 Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure May 2014 September 2015
NCT01993537 Completed Phase 4 The Role of Vitamin D in the Pathophysiology of Chronic Failure January 2013 January 2016
NCT02000479 Completed N/A Influence of Exercise Therapy on Insulin Resistance in Patients With Heart Failure April 2011 October 2011
NCT02013739 Completed Description of Insulin Resistance in Patients With Chronic Heart Failure May 2011 December 2013
NCT02032004 Completed Phase 3 Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart Failure. February 14, 2014 May 29, 2020
NCT02044471 Completed N/A The IMPULSE Study: Pilot August 2014 December 2016
NCT02046707 Completed N/A Evaluation of the Effects of Eccentric Muscle Training Versus Conventional Concentric Training in Chronic Heart Failure August 29, 2014
NCT05848206 Completed Impact of Formulary Coverage of Entresto (Sacubitril/Valsartan) on Prescription Abandonment/Rejection and Subsequent Treatment and Economic Outcomes in Chronic Heart Failure Patients in the U.S. March 11, 2022 April 29, 2022
NCT02065141 Completed N/A Method To Measure Protein Digestion & Absorption November 2014 January 19, 2019
NCT02068118 Completed N/A Optimization of the Ambulatory Monitoring for Patients With Heart Failure by Tele-cardiology May 2013 September 28, 2018
NCT05843201 Completed N/A AquaPass Device in Treatment of CHF Patients February 20, 2022 December 12, 2023
NCT02087670 Completed N/A Natriuretic Brain Pro-peptid Changes in Patients With Chronic Heart Failure Within a Cardiac Rehabilitation Program March 2005 January 2008
NCT02110433 Completed N/A Heart Failure Educational and Follow up Platform December 2013 October 2017
NCT02133859 Completed Adaptive Servo-ventilation Monitoring Study May 2014 March 2016
NCT02188784 Completed Phase 3 Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure September 3, 2014 April 6, 2016
NCT02196922 Completed N/A Telehealth Management in HF Disparity Patients January 1, 2014 April 30, 2017
NCT02219451 Completed Phase 4 Exercise Improve Sympathetic Modulation in Chronic Heart Failure Patients August 2013 July 2014
NCT02223624 Completed N/A Effect of an Eccentric Exercise Program on Quality of Life and Function in People With Chronic Heart Failure. August 2014 March 2019
NCT02232126 Completed N/A Social Work Intervention Focused on Transitions February 2011 October 2013
NCT02247245 Completed N/A The Influence of Heart Rate Limitation on Exercise Tolerance in Pacemaker Patients. September 2014 September 2015
NCT02263482 Completed N/A Inspiratory Muscle and Peripheral Muscle Training in Chronic Heart Failure October 2012 December 2015
NCT02268500 Completed Phase 4 VAccination to Improve Clinical outComes in Heart Failure Trial: a Feasibility Study (VACC-HeFT) September 2014 May 2016
NCT02293252 Completed N/A CardioBBEAT - Randomized Controled Trial to Evaluate the Health Economic Impact of Remote Patient Monitoring March 2009 October 2016
NCT02367716 Completed Post-market Study of Multi-Vector Left Ventricular Lead Performance in Chinese Patients With Chronic Heart Failure December 2014 March 2017
NCT06299826 Not yet recruiting Phase 2 A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure June 10, 2024 November 24, 2025
NCT05934565 Not yet recruiting N/A Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF June 30, 2024 June 30, 2028
NCT06360380 Not yet recruiting N/A Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System July 3, 2024 December 29, 2024
NCT04996550 Not yet recruiting Are Carvedilol and Metoprolol Succinate Comparable Treatments in Heart Failure Patients With Reduced Ejection Fraction January 3, 2022 December 18, 2028
NCT06266988 Not yet recruiting Phase 1 A Bioequivalence Study of Sacubitril/Valsartan Film-coated Tablets Under Fasting Conditions March 2024 August 2024
NCT05090202 Not yet recruiting Prediabetes and Newly Diagnosed Diabetes in Chronic Heart Failure December 30, 2022 January 30, 2023
NCT06117722 Not yet recruiting TorasEmide Induced Effect on Quality of Life and Clinical parameterS in paTients With chronIc heArt Failure Receiving Eplerenone. March 1, 2024 December 31, 2025
NCT03416361 Not yet recruiting N/A VItamiN D treatIng Chronic heArT Failure (the Effect of Vitamin D Supplementation in Patients With Heart Failure) December 1, 2023 March 1, 2027
NCT05862350 Not yet recruiting N/A Effects of Lavender Essential Oil in Patients With Chronic Heart Failure May 10, 2023 October 30, 2023
NCT03759405 Not yet recruiting Phase 2/Phase 3 IPS Differentiated Cardiomyocytes Vein Transplantation for Chronic Heart Failure December 31, 2022 December 31, 2024
NCT06019169 Not yet recruiting N/A Impact of YOGA on the Quality of Life and Well-being of Heart Failure Patients August 30, 2023 March 30, 2025
NCT06002321 Not yet recruiting Right Ventricular Dysfunction in Chronic Heart Failure September 1, 2023 September 1, 2026
NCT06401109 Not yet recruiting N/A Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry February 2025 May 2026
NCT02970214 Recruiting Follow-up of GANI_MED Cardio Cohorts November 2016 December 2024
NCT05566600 Recruiting Early Phase 1 Allogeneic iPSC-derived Cardiomyocyte Therapy in Patients With Worsening Ischemic Heart Failure October 9, 2022 July 31, 2025
NCT05876533 Recruiting R&D Study to Evaluate Cordio's Usability and to Collect Patient Speech Utterances March 18, 2022 September 30, 2024
NCT06386640 Recruiting A Holistic Patient-centred Intervention to Improve Outcomes of Older People Living With Frailty and Chronic Heart Failure January 27, 2023 April 30, 2025
NCT03020043 Recruiting Evaluation of Longterm Outcome of New York Heart Association Class III Heart Failure Patients Receiving Telemonitoring Using a Pulmonary Artery Pressure Sensor System (CardioMEMS) August 2016 December 2025
NCT03966729 Recruiting Relationships and Differences Analysis in Heart Failure January 1, 2009 December 31, 2023
NCT06130319 Recruiting Correlation of Disease Management and Quality of Life in Patients With Chronic Heart Failure and Their Family Caregivers November 2023 June 2024
NCT04332536 Recruiting N/A Limitations of Aerobic Capacity in Chronic Heart Failure December 1, 2019 August 30, 2023
NCT03945968 Recruiting The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. July 1, 2019 February 28, 2025
NCT05966415 Recruiting Phase 2 Endocalyx for Heart Failure April 21, 2023 October 2026
NCT05379608 Recruiting N/A Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection. December 10, 2021 April 30, 2024
NCT04829591 Recruiting A Multicenter Registry to Study the Characteristics and Outcomes of Jordanian Heart Failure Patients. July 1, 2021 December 30, 2024
NCT06036615 Recruiting N/A The Effect of Exercise Training and Detraining on Frailty and Fall Risk in Patients With Chronic Heart Failure October 1, 2023 March 15, 2025
NCT04441203 Recruiting N/A Patient SELF-management With HemodynamIc Monitoring: Virtual Heart Failure Clinic and Outcomes May 4, 2020 June 2024
NCT02051712 Recruiting Phase 3 Cardiovascular Effects of Preferred Home-based Exercise Training in Systolic Heart Failure February 2014 December 2024
NCT05666518 Recruiting A Study to Learn More About the Safety of the Drug Vericiguat in Japanese People With Chronic Heart Failure Who Will be Receiving Vericiguat Under Real-world Conditions August 31, 2022 May 31, 2027
NCT03781427 Recruiting Phase 3 Tailoring Pacemaker Output to Physiology in Chronic Heart Failure February 1, 2020 August 1, 2023
NCT04941794 Recruiting Biomarkers as Predictors of Chronic Heart Failure in Patients With Type 2 Diabetes July 1, 2021 July 2027
NCT03125720 Recruiting N/A Image Fusion of SPECT MPI and Fluoroscopy Venography to Guide LV Lead Placement for Improved CRT Response (GUIDE-CRT II) April 14, 2017 June 2024
NCT05802849 Recruiting Phase 4 Acetazolamide Per os for Decompensation of Heart Failure May 1, 2023 September 1, 2024
NCT05659420 Recruiting N/A High Intensity Interval Training in Chronic Heart Failure January 1, 2023 December 31, 2025
NCT05793996 Recruiting Phase 4 The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF) April 28, 2023 December 2026
NCT05089162 Recruiting N/A CHF-COV Reduced (Chronic Heart Failure With Reduced Ejection Fraction - COngestion eValuation) December 14, 2021 June 14, 2029
NCT04970888 Recruiting N/A Comparing the Effects of Cognitive Training and Physical Exercise on Cognition, Cerebral Autoregulation and Cerebral Vasoreactivity in Men and Women With Heart Failure September 1, 2021 September 1, 2025
NCT06017609 Recruiting Phase 2 Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction December 20, 2023 September 2025
NCT03955029 Recruiting N/A Interval Training in Heart Failure January 10, 2020 January 10, 2025
NCT05690009 Recruiting Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease February 27, 2023 December 31, 2023
NCT02776384 Recruiting Prognostic and Diagnostic Value of Biomarkers and Cardiac Functional Parameters in Patients With Chronic Heart Failure December 2015
NCT04947670 Recruiting N/A A Prospective, Multicenter, Randomized, Blinded, Sham-controlled, Feasibility Study of Renal Denervation in Patients With Chronic Heart Failure June 13, 2022 May 1, 2026
NCT05202938 Recruiting eMESH Struct. 2022-23 July 21, 2022 July 21, 2024
NCT06270498 Recruiting Phase 4 Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure March 14, 2024 June 14, 2025
NCT05633784 Recruiting N/A Telemedicine Home-based Management in Patients With CHF and Type 2 Diabetes August 18, 2022 September 30, 2024
NCT05327062 Recruiting N/A Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment March 6, 2023 September 2024
NCT05913739 Recruiting N/A Oxygen Therapy in Patients With Chronic Heart Failure With Reduced Ejection Fraction July 1, 2023 December 31, 2024
NCT05659264 Recruiting Phase 1 A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure December 5, 2022 March 6, 2025
NCT06423599 Recruiting Phase 2/Phase 3 Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure May 17, 2024 December 30, 2026
NCT05097898 Recruiting N/A Chronic Heart Failure With Preserved Ejection Fraction - COngestion eValuation August 10, 2022 June 10, 2029
NCT05089149 Recruiting N/A Chronic Heart Failure - COngestion eValuation December 14, 2021 June 14, 2029
NCT03388593 Recruiting Phase 3 Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure. July 23, 2018 February 2026
NCT01235273 Suspended Phase 2 Treatment of the lOw IGF-1 Syndrome aSsociated With Chronic Heart fAilure: A Randomized, Placebo-Controlled, Double-Blind Study. January 2011 February 2014
NCT03159988 Suspended Phase 2 Angiotensin (1-7) Treatment to Improve Cognitive Functioning in Heart Failure Patients April 2016 November 15, 2022
NCT02625922 Terminated Phase 2 Study of the Effect of Serelaxin on High-sensitivity Cardiac Troponin I (Hs-cTnI) Release in Patients With Chronic Heart Failure February 5, 2016 January 11, 2017
NCT00151619 Terminated Phase 2 Effects of Amlodipine in the Management of Chronic Heart Failure February 10, 1999
NCT00348829 Terminated Phase 2 Mitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Therapy June 2006 September 2012
NCT00511888 Terminated Nebivolol Versus Carvedilol in Patients With Heart Failure January 2004 June 2007
NCT00534703 Terminated Phase 2 Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure July 2014 September 2015
NCT00679484 Terminated Phase 3 Study to Demonstrate the Non-inferiority of Olmesartan Medoxomil Versus Candesartan Cilexetil in Reducing Blood B-type (or Brain) Natriuretic Peptide Levels at Week 24 June 2008 November 2009
NCT00739687 Terminated Phase 2 Safety & Efficacy of ALT-711 (Alagebrium) in Chronic Heart Failure August 2008 October 2009
NCT00821717 Terminated Phase 3 EFfect of Ferric Carboxymaltose on exercIse CApacity and Cardiac Function in Patients With Iron deficiencY and Chronic Heart Failure December 2008 January 2011
NCT01023438 Terminated N/A Strategies to Improve Prescribing in Heart Failure Patients January 2010 April 2017
NCT01131637 Terminated Phase 3 Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients April 2010 August 2012
NCT01214096 Terminated Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Recombinant Human Neuregulin-1 for Subcutaneous Administration in Patients With Chronic Systolic Heart Failure July 2010 January 2011
NCT01439789 Terminated Phase 3 Study of Efficacy on NT-proBNP of Recombinant Human Neuregulin-1 in Chronic Heart Failure Patients June 2011 June 2012
NCT01535196 Terminated Phase 3 Vitamine D Treatment in Chronic Heart Failure December 2012 September 2017
NCT01541202 Terminated Phase 3 Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients February 2012 August 2017
NCT01696890 Terminated Phase 2 Integration of Follow-up by First and Second Line Practitioners by Telemonitoring in Heart Failure. October 2011 December 2013
NCT01794598 Terminated N/A Preliminary Study Examining Heart Failure Patients Responses to Depression Education May 2004 December 2006
NCT01906957 Terminated N/A Cognition and Exercise Training September 2013 September 9, 2022
NCT02596477 Terminated Phase 2 Evaluation of Vepoloxamer in Chronic Heart Failure October 2015
NCT03262571 Terminated Phase 3 Usefulness of Lung Ultrasound in Ambulatory Management of Patients With Chronic Heart Failure December 2010 March 2016
NCT03494933 Terminated N/A Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure September 1, 2018 February 21, 2023
NCT04065997 Terminated Apogee International September 6, 2019 July 26, 2021
NCT05532046 Terminated Phase 1 A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT) September 20, 2022 March 31, 2023
NCT04758429 Unknown status International Multi-center Study to Validate an Early Warning Algorithm for Worsening Heart Failure May 31, 2021 May 31, 2022
NCT04471129 Unknown status N/A Non-invasive Ventilation and High-speed Oxygen Therapy Effects on Heart Function - HiFlow-Heart Study July 15, 2020 October 15, 2022
NCT04370600 Unknown status Phase 1 Nutritional Ketosis in Heart Failure June 2020 June 2021
NCT04917159 Unknown status N/A Acceptance and Commitment Therapy for Patients With Chronic Heart Failure and Their Caregivers on Their Quality of Life June 10, 2022 December 31, 2023
NCT04127162 Unknown status Heart Failure Decompensation And In-Hospital Mortality December 2019 April 2020
NCT03892148 Unknown status Phase 4 Protocol of Diuretics Use in Congestive Therapy in Heart Failure May 17, 2019 December 2021
NCT04949945 Unknown status N/A Efficacy of CBT on Positive Health Outcomes of Chronic Heart Failure Patients With Depression February 1, 2021 November 29, 2021
NCT03840499 Unknown status The Role of Willingness of Participation in Cardiology Trials on the Survival of Patients October 1, 2018 December 31, 2022
NCT03821701 Unknown status N/A Effect of Angiotensin-Neprilysin Inhibition (ARNI) on Prognosis of Chronic Heart Failure June 1, 2018 January 31, 2022
NCT04984928 Unknown status Readmission Risk of Patients With Heart Failure. September 20, 2021 December 30, 2022
NCT03718780 Unknown status N/A Assessment of Continuous Measurement of Transcutaneous CO2 for Evaluation of Alveolar Dead Space During Exercise February 22, 2019 February 22, 2024
NCT05021419 Unknown status N/A Efficacy of a Streamlined Heart Failure Optimization Protocol August 2021 February 2023
NCT01124136 Unknown status N/A Neurostimulation of Spinal Nerves That Affect the Heart May 2010 November 2018
NCT01071629 Unknown status N/A Exercise Training Effects in Patients With Heart Failure November 2004 September 2015
NCT00893685 Unknown status N/A Randomized Controlled Trial of Home Telemonitoring for Elderly People May 2009 December 2011
NCT00863421 Unknown status Sleep Disordered Breathing in Patients With Chronic Heart Failure September 2008 May 2012
NCT00668408 Unknown status Phase 4 LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure May 2008 October 2012
NCT00646243 Unknown status Echo Assessment of Intraventricular Dyssynchrony March 2008 March 2009
NCT00468637 Unknown status Association of Multiple CardiOvascular Risk Factors and Erectile Function Across Europe May 2007 September 2011
NCT03615157 Unknown status N/A Effects of a Home-based Exercise Program on Functional Capacity and Quality of Life in Heart Failure Patients January 15, 2018 February 15, 2019
NCT03474315 Unknown status Interactive Patient's Assistant - LUCY April 2018 February 2019
NCT03351400 Unknown status Phase 1 Japanese OMI Treatment With Kit-positive Cells for Enhanced Regeneration November 15, 2017 March 2022
NCT03344523 Unknown status Phase 4 Evaluating Iron Protein Succinylate Oral Solution in Treating Chronic Heart Failure and Iron Deficiency January 2018 December 2019
NCT03333499 Unknown status Phase 1 the Effects of YangXinShi (YXS) on the Quality of Life and Exercise Tolerance in Patients With Chronic Heart Failure November 1, 2017 December 2018
NCT03286127 Unknown status Palliative Outcome Evaluation Muenster I September 11, 2017 December 2019
NCT03254212 Unknown status Phase 4 Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure. April 15, 2018 December 31, 2022
NCT03153774 Unknown status N/A Assessments of Sarcopenia Prevalence in Chronic Heart Failure Patients and in Subjects Before TAVI November 3, 2014 December 2018
NCT03042039 Unknown status Multi-level Integration for Patients With Complex Needs Facilitated by ICTs. A Shared Approach, Mutual Learning and Evaluation Are Expected to Create Synergies Among the Partners and to Bring Forward Integration of Care in Europe January 1, 2015 October 1, 2017
NCT02832739 Unknown status N/A Exploring Acceptance and Outcomes of an Online-based Self-management Support System in Chronic Illness November 2016 August 31, 2017
NCT05232292 Unknown status Phase 4 Influenza Vaccination During Coronavirus Disease 2019 Outbreak After Acute Coronary Syndrome and Chronic Heart Failure October 6, 2021 May 31, 2023
NCT02794935 Unknown status N/A The Effects of Inspiratory Muscle Training in Patients With Heart Failure and Obstructive Sleep Apnea Syndrome June 2016 December 2017
NCT02732990 Unknown status N/A Peripheral Metabolic Function in Chronic Heart Failure Patients February 2014 August 2016
NCT02732106 Unknown status Characterization of Adipose Derived Regenerative Cells (ADRCs) From Patients With Chronic Heart Disease April 2013 September 2019
NCT02563873 Unknown status N/A Bowditch Revisited: Defining the Optimum Heart Rate Range in Chronic Heart Failure October 2015 July 2018
NCT02559128 Unknown status The Role of Insulin Resistance in Patients With Heart Failure and Type 2 Diabetes December 2013 December 2019
NCT02541773 Unknown status Novel Vascular Biomarkers Behaviour and Clinical Value in Heart Failure and CRT November 2013 June 2016
NCT00125996 Unknown status Phase 1/Phase 2 Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure July 2004 February 2006
NCT02493907 Unknown status Corrected Left Ventricular Electrical Delay Predicting Response to Cardiac Resynchronization Therapy December 2014 December 2018
NCT02486887 Unknown status N/A Home Electronic Monitoring of Chronic Heart Failure June 2015 September 2020
NCT02471729 Unknown status Phase 1/Phase 2 Effect at 6 Months of Renal Denervation in Chronic Heart Failure d'Insuffisance Cardiaque January 2017 January 2018
NCT02335801 Unknown status The TOSCA Registry: Hormonal and Metabolic Deficiencies in Chronic Heart Failure April 2013 December 1, 2019
NCT02322034 Unknown status N/A Interval Training and Hormones in Chronic Heart Failure January 2015 January 2019
NCT02292030 Unknown status Cardioversion of Atrial Fibrillation Accompanied by Chronic Heart Faliure November 2014 October 2015
NCT02282618 Unknown status Effects of Cardiac Sympathetic Blockade in Patients With Chronic Heart Failure May 2013
NCT02137733 Unknown status N/A The Cardiac Insufficiency BIsoprolol Study in Japanese Patients With Chronic Heart Failure (CIBIS-J) June 2013
NCT02087332 Unknown status Phase 4 Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics. April 2014 May 2015
NCT02086422 Unknown status N/A Iatrogenic Chronotropic Incompetence and Exercise Tolerance in Heart Failure July 2013
NCT02051985 Unknown status N/A Early-start Exercise Training in Subacute Heart Failure October 2013 September 2015
NCT02029287 Unknown status N/A Hospital-Community-Family-Care Management Platform for Chronic Heart Failure December 2013 December 2020
NCT01979120 Unknown status Validation of the "ApneaScan" Algorithm for the Detection of Sleep Disordered Breathing in Chronic Heart Failure December 2012
NCT01864733 Unknown status N/A Multimodal Approach of Undernutrition in Chronic Heart Failure May 2013 May 2016
NCT01855165 Unknown status N/A The Role of Clinical Pharmacist in Management of DDIs in CHF Patients April 2013 December 2013
NCT01829880 Unknown status Impact of Body Composition on Bisoprolol and Ramipril Pharmacokinetics in Patients With Chronic Heart Failure October 2011 August 2013
NCT01790906 Unknown status N/A Renal Sympathetic Denervation for Patients With Chronic Heart Failure January 2013 April 2017
NCT01700218 Unknown status N/A Integrated Telemonitoring and Nurse Support Evaluation October 2012 October 2015
NCT01669395 Unknown status N/A Severe Heart Failure and Homebased Rehabilitation - An Intersectoral Randomized Controlled Trial September 2012 July 2016
NCT01543022 Unknown status Phase 1/Phase 2 Symphony: The Implantable Counter Pulsation Device (CPD) Safety and Feasibility Trial November 2011 June 2014
NCT01461434 Unknown status Phase 4 Graz Study on the Risk of Atrial Fibrillation November 2011 January 2016
NCT01307722 Unknown status N/A Left Atrial Distensibility Guiding Management in Advanced Chronic Heart Failure August 2011 August 2014
NCT01212705 Unknown status N/A Effect of Adaptive Servoventilation on Cardiac Function in Chronic Heart Failure and Cheyne-Stokes Respiration
NCT01139086 Unknown status Role of Endothelial Function, Muscular Fitness and Metabolism in Functional Activity in Patients With Chronic Heart Failure (CHF) May 2010 May 2011
NCT03675113 Withdrawn N/A Effect of Upper Extremity Aerobic Exercise Training on Exercise Capacity Patients With Chronic Heart Failure September 5, 2018 December 2020
NCT02511912 Withdrawn N/A Heart Failure (HF) Interatrial Shunt Study 1 March 2017 May 2022
NCT02085668 Withdrawn N/A Renal Denervation in Patients With Chronic Heart Failure May 2014 May 2019
NCT04854200 Withdrawn HVAD(TM) SMART 1.0 Study May 1, 2021 August 22, 2025
NCT00384657 Withdrawn Phase 3 Intravenous Iron in Patients With Severe Chronic Heart Failure and Chronic Kidney Disease January 2008 December 2017
NCT00567645 Withdrawn Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT) July 2007
NCT01886391 Withdrawn N/A Health Behavior-Related Outcomes With Diaphragmatic Breathing Retraining in Heart Failure Patients November 2011 May 15, 2012