Monoclonal Gammopathy of Undetermined Significance

Search with Google Search with Bing
Information
Disease name
Monoclonal Gammopathy of Undetermined Significance
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04920084 Active, not recruiting N/A A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) June 3, 2021 June 2025
NCT03327597 Active, not recruiting N/A Iceland Screens, Treats or Prevents Multiple Myeloma September 1, 2016 September 1, 2026
NCT03855878 Active, not recruiting Observation of the Incidence and Natural History of MGUS in Patients Undergoing Weight Reduction Surgery November 8, 2018 August 8, 2024
NCT00025415 Completed Phase 1 Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction August 2001
NCT04439006 Completed Phase 1 Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization October 23, 2020 September 20, 2022
NCT04615572 Completed Screening to Improve Survival in AL Amyloidosis August 28, 2020 July 6, 2023
NCT00919139 Completed S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS. November 2003 November 2010
NCT01219010 Completed Phase 1 A Study Evaluating the Effects of Siltuximab on the Heart in Patients With Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma, or Indolent Multiple Myeloma October 2010 March 2014
NCT01237054 Completed Phase 2 Imaging in MGUS, SMM and MM October 17, 2010 August 9, 2011
NCT00099047 Completed Phase 2 Celecoxib in Preventing Multiple Myeloma in Patients With Monoclonal Gammopathy or Smoldering Myeloma November 2004 November 2008
NCT01588015 Completed Phase 1 Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant October 29, 2012 February 2, 2024
NCT01955395 Completed N/A Genomic and Psychosocial Effects of the 3RP on Patients With MGUS and Smoldering Multiple Myeloma October 2013 September 2016
NCT05969821 Not yet recruiting Clonal Hematopoiesis of Immunological Significance September 2023 September 2043
NCT04702932 Not yet recruiting Establishment of Genomic, Transcriptomic and Functional Characteristics of Tumor Cells in Hyperinflammatory Hemopathies September 1, 2021 September 1, 2036
NCT06383143 Recruiting Promoting Diagnosis and Management of AL in Italy (ProDigALIty) May 1, 2023 May 1, 2025
NCT01408225 Recruiting Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource March 17, 2011 March 2050
NCT02726750 Recruiting Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma December 14, 2015 April 30, 2026
NCT03119883 Recruiting N/A Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma June 2, 2017 June 30, 2024
NCT04114084 Recruiting Sleep Apnea in Patients With MGUS and MM May 23, 2019 May 23, 2024
NCT04850846 Recruiting Phase 2 Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma April 27, 2021 July 31, 2025
NCT05136807 Recruiting Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies June 7, 2016 February 2, 2027
NCT05361694 Recruiting Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions April 12, 2022 July 1, 2027
NCT05640843 Recruiting N/A A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) November 29, 2022 November 2026
NCT05831358 Recruiting N/A Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program June 16, 2023 April 30, 2025
NCT05965115 Recruiting The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study July 2023 August 2035
NCT06046287 Recruiting Phase 2 Daratumumab for Polyneuropathy Associated With MGUS June 2024 December 2026
NCT04731844 Recruiting Phase 2 Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer December 14, 2021 May 31, 2024
NCT00899353 Terminated Phase 2 Prevention of Disease Progression in Early Stage Indolent B Cell Malignancies. (SMM) August 2008 October 2012
NCT01079429 Terminated Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. January 12, 2009 September 2019
NCT01109407 Terminated Natural History Study of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Myeloma (SMM) April 22, 2010 February 25, 2021
NCT05114109 Unknown status Phase 2 Isatuximab in Type I Cryoglobulinemia November 1, 2021 December 31, 2023
NCT04727294 Unknown status MGUS, SMM, and MM Patient Experience With Coronavirus 19 (COVID-19) Survey January 22, 2021 December 2021
NCT02298816 Withdrawn B-Cell Hematologic Malignancy Vaccination Registry August 2014 December 2025
NCT01571726 Withdrawn Phase 2 Imaging Studies and the Development of Multiple Myeloma March 27, 2012 April 23, 2014
MeSH unique ID (MeSH (Medical Subject Headings))
D008998