ocular hypertension

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Information
Disease name
ocular hypertension
Disease ID
DOID:9282
Description
"An eye disease that is characterized by elevated intraocular pressure in the absence of optic nerve damage or visual field loss." [url:https\://en.wikipedia.org/wiki/Ocular_hypertension]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03519386 Active, not recruiting Phase 3 Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5% July 26, 2018 June 2024
NCT04036214 Active, not recruiting Efficacy and Safety Outcomes of Optometrist Performed Selective Laser Trabeculoplasty (SLT) August 21, 2019 August 30, 2022
NCT03868124 Active, not recruiting Phase 3 Clinical Study Comparing Two Models of a Travoprost Intraocular Implant September 17, 2018 June 2024
NCT05335122 Active, not recruiting Phase 2 A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT) March 16, 2022 January 2025
NCT03850782 Active, not recruiting Phase 3 Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension February 28, 2019 August 9, 2025
NCT06061718 Active, not recruiting Phase 3 Travoprost Intraocular Implant in Conjunction With Cataract Surgery September 11, 2023 December 20, 2024
NCT05456724 Active, not recruiting Phase 1/Phase 2 A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular Hypertension August 4, 2022 July 31, 2024
NCT03798223 Active, not recruiting N/A Optimal Treatment Protocol for Selective Laser Trabeculoplasty January 10, 2019 May 31, 2025
NCT05389267 Active, not recruiting Phase 1/Phase 2 Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients. July 5, 2022 December 31, 2024
NCT03928665 Active, not recruiting Long-term Observation of Ophthalmic Changes in Patients With Obstructive Sleep Apnea October 1, 2012 October 1, 2027
NCT00051181 Completed Phase 3 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma January 2000 June 2003
NCT00051194 Completed Phase 2 A 6-week Safety & Efficacy Study of Combination Intraocular Pressure-lowering Therapy in Patients With Open-angle Glaucoma or Ocular Hypertension September 2002 July 2003
NCT00061503 Completed Phase 4 Mechanism of Action of TRAVATAN 0.004% in Subjects With Glaucoma or Ocular Hypertension April 2003 March 2004
NCT00061516 Completed Phase 3 Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertension January 2003 February 2006
NCT00061529 Completed Phase 3 A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension January 2003 July 2004
NCT00061542 Completed Phase 3 Safety and Efficacy Study of BETOPTIC S 0.25% and Timolol Gel-forming Solution 0.25% and 0.5% in Pediatric Patients With Glaucoma or Ocular Hypertension January 2003 November 2006
NCT00069706 Completed Phase 2 Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patients July 2003 October 2003
NCT00069719 Completed Phase 2 Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients February 1999 August 2003
NCT00108017 Completed Phase 3 Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED) April 2005 July 2006
NCT00121147 Completed N/A Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan September 2003 October 2005
NCT00140049 Completed Phase 4 A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma July 2005 July 2006
NCT00140062 Completed Phase 4 Efficacy And Safety Of Xalatan Compared To Usual Care In Patients With Open Angle Glaucoma Or Ocular Hypertension. February 2002 April 2006
NCT00143208 Completed Phase 4 Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh. May 2003 April 2006
NCT00150267 Completed Phase 3 A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertension February 2002
NCT00159653 Completed Phase 3 A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma July 2005 June 2007
NCT00168363 Completed Phase 3 Safety and Efficacy of Brimonidine in Patients With Glaucoma or Ocular Hypertension January 2005 August 2006
NCT00219596 Completed Phase 3 Xalacom And Combination Of Unfixed Latanoprost And Timolol In Subjects With Open-Angle Glaucoma Or Ocular Hypertension June 2005 September 2006
NCT00230763 Completed Phase 3 Determination Of Predictive Factors Allowing To An Additional 10% Reduction Of Intra-Ocular Pressure September 2005 October 2007
NCT00273429 Completed Phase 4 Cosopt Versus Xalatan April 2005 December 2005
NCT00273442 Completed Phase 4 Assessing Cosopt Switch Patients November 2005 April 2007
NCT00273481 Completed Phase 4 Cosopt Versus Xalacom September 2005 April 2007
NCT00277498 Completed Phase 3 A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma December 2005 June 2007
NCT00287521 Completed Phase 2 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension November 2005 February 2006
NCT00288951 Completed Phase 3 Phase III Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients October 2004 June 2005
NCT00293761 Completed Phase 3 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension January 2006 May 2006
NCT00293787 Completed Phase 3 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension June 2004 August 2005
NCT00293800 Completed Phase 3 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension July 2004 December 2005
NCT00300079 Completed Phase 4 Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension September 2006 September 2007
NCT00300443 Completed Phase 2/Phase 3 Safety and Efficacy Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension December 2005 June 2007
NCT00304785 Completed Phase 4 Latanoprost Versus Fotil May 2005 October 2007
NCT00311389 Completed Phase 3 A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension January 2003 September 2004
NCT00314158 Completed Phase 3 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension November 2005 January 2007
NCT00314171 Completed Phase 3 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension October 2005 August 2007
NCT00326092 Completed Phase 2 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension May 2006 August 2006
NCT00329095 Completed Phase 4 An Evaluation of Use of Topical Ocular Hypotensive Medication by Compliance December 2005 April 2006
NCT00330577 Completed Phase 4 24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients April 2006 July 2007
NCT00332059 Completed Phase 3 Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension May 2003 September 2004
NCT00332072 Completed Phase 3 Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients Wtih Glaucoma or Ocular Hypertension August 2001 August 2003
NCT00332345 Completed Phase 2 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension July 1999 August 1999
NCT00332384 Completed Phase 3 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension January 2000 November 2001
NCT00332436 Completed Phase 3 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension December 1999 November 2001
NCT00332540 Completed Phase 3 Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension August 2001 August 2003
NCT00333125 Completed Phase 3 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension April 2006 February 2007
NCT00334750 Completed Distribution of Risk Factors in Ocular Hypertension and Open-Angle Glaucoma Patients in Canada November 2007 April 2009
NCT00347191 Completed Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments. January 2006 June 2006
NCT00372827 Completed Phase 4 Study of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular Hypertension February 2004 January 2006
NCT00372931 Completed Phase 2 A Phase II Study of AL-37807 to Treat Open-Angle Glaucoma or Ocular Hypertension May 2006
NCT00383019 Completed Phase 3 A Study Comparing Xalacom And Xalatan In Patients With Primary Open Angle Glaucoma (POAG) Or Ocular Hypertension (OH). November 14, 2006 October 1, 2007
NCT00402493 Completed N/A Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops December 2006 March 2008
NCT00424996 Completed Utility of Heidelberg Retina Tomograph in Monitoring Glaucoma Progression August 2006 December 2013
NCT00429819 Completed Neurovascular Coupling in Eyes of Glaucoma Patients December 2006 December 2014
NCT00430209 Completed Neurovascular Coupling in Eyes of Glaucoma Patients December 2006 December 2013
NCT00440011 Completed Phase 4 Bimatoprost 0.03% Versus Travoprost 0.004% in Patients Currently on Latanoprost 0.005% August 2006 October 2007
NCT00440141 Completed Phase 4 Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005% July 2006 March 2007
NCT00441883 Completed Phase 2 Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucoma March 2007 July 2008
NCT00443924 Completed Phase 1 Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma March 2007 April 2009
NCT00457795 Completed Phase 4 24-hour IOP-lowering Effect of Brimonidine 0.1% December 2006 February 2009
NCT00465621 Completed Phase 2 Dose Response Study of AL-37807 Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension March 2007
NCT00465803 Completed Phase 3 A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension March 2007
NCT00471380 Completed Phase 4 A Phase IV Study of Travoprost + Brinzolamide to Treat Glaucoma or Ocular Hypertension March 2007
NCT00486252 Completed Non Interventional Study in Patients With Open Angle Glaucoma and/or Ocular Hypertension Treated With XALATAN® June 2007 January 2008
NCT00503360 Completed Phase 1 Tolerability, Safety and Efficacy of SAD448 in Subjects With Ocular Hypertension April 2007
NCT00508469 Completed Phase 4 Adherence Assessment With Travalert Dosing Aid October 2007 January 2010
NCT00515424 Completed Phase 1 Tolerability, Safety and Efficacy of RKI983 Eye Drops in Subjects With Primary Open Angle Glaucoma and Ocular Hypertension July 2007
NCT00527501 Completed Phase 2 IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension August 2007 December 2007
NCT00527592 Completed Phase 4 A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension May 2007 August 2008
NCT00538304 Completed Phase 2 A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular Hypertension November 2007 May 2008
NCT00539526 Completed Phase 4 Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues September 2007 September 2008
NCT00541242 Completed Phase 4 Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular Hypertension December 2007 August 2008
NCT00545064 Completed Phase 4 Dry Eye Study With Cosopt® Over 8 Weeks in Patients With Open-Angle Glaucoma or Ocular Hypertension (0507A-152)(COMPLETED) May 23, 2007 September 15, 2008
NCT00546286 Completed Phase 3 A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153) May 31, 2006 August 23, 2007
NCT00572455 Completed Phase 2 Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure. December 11, 2007 June 26, 2009
NCT00576342 Completed Phase 3 Patient Preference Study December 2007 January 2008
NCT00595101 Completed Phase 2 A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension. December 2007 June 2008
NCT00596791 Completed Phase 3 Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops January 2008 August 2008
NCT00620256 Completed Phase 2 Adjunctive Study of AL-37807 Ophthalmic Suspension November 2007 July 2008
NCT00621335 Completed A Investigator Masked Parallel Comparison of Tolerability of Combigan and Cosopt March 2007 February 2008
NCT00637130 Completed Phase 2 Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost October 2007
NCT00638742 Completed Phase 1 A Phase 1, Open-Label Study of Latanoprost Acid Plasma Concentrations in Pediatric and Adult Glaucoma Patients Treated With Latanoprost. May 2008 March 2009
NCT00647101 Completed Phase 4 A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucoma December 2003 February 2005
NCT00650338 Completed Phase 2 Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension March 2008 October 2008
NCT00650702 Completed Phase 2 Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension March 2008 February 2009
NCT00651612 Completed Phase 3 Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension Patients November 2005 January 2007
NCT00651859 Completed Phase 2 Safety and Efficacy Study of Bimatoprost in Ethnically Japanese Patients With Open-Angle Glaucoma or Ocular Hypertension November 2002 January 2004
NCT00652106 Completed Phase 3 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension June 2003 March 2004
NCT00652483 Completed Phase 3 Safety and Efficacy Study of Brimonidine in Patients With Glaucoma or Ocular Hypertension May 2003 September 2004
NCT00652496 Completed Phase 2 Safety and Efficacy Study of Different Formulations of Bimatoprost Once-Daily in Patients With Glaucoma or Ocular Hypertension January 2005 May 2005
NCT00656240 Completed Phase 2 To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00657579 Completed Phase 2 Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00670033 Completed Phase 2 Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension April 2008 September 2008
NCT00672997 Completed Phase 3 A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension May 2008 December 2008
NCT00675207 Completed Phase 4 Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs January 2006 July 2007
NCT00676637 Completed Glaucoma Adherence Study May 2008 February 2010
NCT00680329 Completed Glaucoma Adherence Study, Spain May 2008 July 2009
NCT00683501 Completed Phase 1/Phase 2 Safety, Efficacy, and Pharmacokinetic Profile of DNB-001 in Subjects With Elevated Intraocular Pressure October 2007 October 2008
NCT00690794 Completed Phase 3 Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertension July 2008 May 2009
NCT00698945 Completed Phase 4 Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG) June 2008 November 2008
NCT00708422 Completed Phase 4 Effects of Travatan Z and Xalatan on Ocular Surface Health July 2008 August 2009
NCT00716742 Completed Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG) September 2004 September 2009
NCT00735449 Completed Phase 4 Comparing Efficacy and Safety of Combigan With Timolol Adjunctive to Xalatan in Glaucoma or Ocular Hypertension Subjects July 2008 December 2009
NCT00751049 Completed Phase 3 A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom December 1992 December 1993
NCT00751062 Completed Phase 3 A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia November 1992 December 1993
NCT00751127 Completed Phase 3 A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension January 1993 February 1994
NCT00753168 Completed Phase 1/Phase 2 Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-Angle Glaucoma September 2008 December 2008
NCT00759239 Completed Phase 4 Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed Dose Combination of Travoprost 0.004% / Timolol Maleate 0.5% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension September 2008 January 2011
NCT00760539 Completed Phase 3 Safety and Efficacy of Travoprost/Timolol BAC-free June 2008 December 2008
NCT00761319 Completed Phase 3 Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health October 2008 September 2009
NCT00761709 Completed Phase 2 Safety and Intraocular Pressure (IOP)-Lowering Efficacy of AL-39256 in Patients With Open-Angle Glaucoma or Ocular Hypertension July 2009 October 2009
NCT00761995 Completed Phase 4 Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertension February 2009 July 2010
NCT02674854 Completed Phase 3 Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension February 2016 March 2017
NCT00001152 Completed Pigment Dispersion Syndrome With and Without Glaucoma June 1976 June 2000
NCT00001161 Completed Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens July 1977 August 2002
NCT00047515 Completed Phase 3 Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-69 January 2001 December 2003
NCT00047528 Completed Phase 3 Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41 January 2001 November 2003
NCT00047541 Completed Phase 3 Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70 February 2001 November 2003
NCT00047593 Completed Phase 3 Phase 3 Study Comparing IOP Lowering in OAG or OH in Japanese Subjects C-01-98 January 2000 July 2004
NCT00051142 Completed Phase 3 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) February 2001 June 2004
NCT00051155 Completed Phase 3 A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT) January 2001 July 2004
NCT00051168 Completed Phase 3 A Long-term Safety Study of Once-daily Travatan January 2006
NCT02083289 Completed Phase 2 A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG) May 2014
NCT02097719 Completed Phase 4 Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension May 2014 December 2014
NCT02102750 Completed Phase 1 A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension June 2014 July 3, 2017
NCT02105272 Completed Phase 3 Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension April 2014 March 2015
NCT02105285 Completed Phase 3 Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension April 2014 January 2015
NCT02108288 Completed Phase 1 Pharmacokinetic Study of OPC-1085EL Ophthalmic Solution in Healthy Male Adult Volunteers April 2014 August 2014
NCT02129673 Completed Phase 1/Phase 2 A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension May 2014 August 2017
NCT02136940 Completed Phase 2 Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension April 2014 December 2014
NCT02140060 Completed Phase 2 6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension June 2014 November 2014
NCT02143843 Completed Phase 2 An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product June 5, 2014 January 31, 2016
NCT02165631 Completed The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure August 2014 March 2016
NCT02167035 Completed Phase 4 Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID) August 2014 March 2018
NCT02179008 Completed Phase 2 Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension June 2014 January 2015
NCT02207491 Completed Phase 3 Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension July 2014 March 2015
NCT02207621 Completed Phase 3 Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension July 2014 March 2016
NCT02246764 Completed Phase 3 Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension September 2014 December 2016
NCT02247804 Completed Phase 3 Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension December 15, 2014 July 19, 2019
NCT02250612 Completed Phase 2 SYL040012, Treatment for Open Angle Glaucoma October 2014 January 2016
NCT02250651 Completed Phase 3 Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension December 15, 2014 July 22, 2020
NCT02278614 Completed Phase 3 Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patients December 2014 November 2015
NCT02312544 Completed Phase 2 Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertension November 2014 December 2015
NCT02325518 Completed Phase 4 Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution December 2014 December 2015
NCT02338362 Completed Phase 4 Inhaled Corticosteroids: Effect on Intraocular Pressure in Patients With Controlled Glaucoma September 2014 February 2015
NCT02339584 Completed Phase 3 Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) April 14, 2015 November 1, 2016
NCT02348476 Completed A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension November 2014 April 2015
NCT02358369 Completed Phase 2 Dose-Ranging Study of the Bimatoprost Ocular Insert January 19, 2015 October 7, 2015
NCT02384772 Completed Survey of Patients Taking IOP-Lowering Eye Drops January 2015 May 2015
NCT02390245 Completed N/A Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study September 2014 August 2020
NCT02419508 Completed Phase 4 SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA) August 7, 2015 February 27, 2018
NCT02434250 Completed N/A Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy May 2015 November 2016
NCT02507687 Completed Phase 3 Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension August 27, 2015 May 31, 2023
NCT02537015 Completed Phase 2 An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Insert August 10, 2015 August 11, 2016
NCT02558374 Completed Phase 3 Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension September 2015 December 2016
NCT02558400 Completed Phase 3 Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension September 18, 2015 June 30, 2017
NCT02571712 Completed Phase 4 Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertension November 10, 2015 June 21, 2018
NCT02617459 Completed Phase 3 Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension January 4, 2019 July 1, 2021
NCT02623738 Completed Phase 2/Phase 3 A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study- December 6, 2015 February 10, 2017
NCT02628223 Completed N/A 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma September 2014 December 2017
NCT00000125 Completed Phase 3 Ocular Hypertension Treatment Study (OHTS) February 1994 June 30, 2019
NCT02710916 Completed N/A SD-OCT Multimodal Analysis in GLaucoma February 22, 2016 December 21, 2018
NCT02742649 Completed Phase 1/Phase 2 A Study to Evaluate Efficacy and Safety of a Fixed Combination Ocular Insert in Participants With Open-angle Glaucoma or Ocular Hypertension April 30, 2016 December 31, 2016
NCT02743780 Completed Phase 1/Phase 2 A Three Part Study of MGV354 in Ocular Hypertension or Glaucoma March 2, 2016 September 20, 2016
NCT02796560 Completed Phase 4 Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension July 1, 2016 September 12, 2017
NCT02863224 Completed Advanced Glycation End Products as a Biomarker for Accelerated Ageing August 2016 September 2018
NCT02874846 Completed Phase 2 Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution July 2016 September 2016
NCT02914509 Completed Phase 3 Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT November 7, 2016 March 30, 2019
NCT02967614 Completed Phase 1 KJ-TFC-004 Drug-drug Interaction Study December 2016 April 1, 2018
NCT02989909 Completed N/A Clinical Evaluation of CATS Tonometer Prism January 2017 November 2017
NCT02993445 Completed N/A Effect of Alternate Therapies on Intraocular Pressure in Ocular Hypertension September 2014 February 2016
NCT03131167 Completed Phase 1 Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma May 10, 2017 May 30, 2018
NCT03192826 Completed Phase 4 Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy June 20, 2016 July 8, 2017
NCT03201354 Completed N/A Efficacy and Safety of the ExPRESS Implant Versus Deep Sclerectomy in Combined Surgery February 2012 June 2016
NCT03204487 Completed Phase 4 A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thickness May 10, 2016 June 30, 2017
NCT03235232 Completed Phase 3 BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension February 1, 2021 October 31, 2023
NCT03257813 Completed Phase 3 Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK) April 1, 2016 June 18, 2017
NCT03284853 Completed Phase 3 Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension September 5, 2017 November 6, 2020
NCT03293992 Completed Phase 1 A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension October 10, 2017 December 21, 2017
NCT03395535 Completed Phase 4 Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension October 1, 2012 December 25, 2017
NCT03419975 Completed Phase 3 A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients April 26, 2016 June 1, 2018
NCT03450629 Completed Phase 3 Evaluation of Safety and Efficacy of PDP-716 September 13, 2018 December 1, 2020
NCT03529591 Completed N/A Is the Reduction in IOP After Treatment of 180 Degrees Equivalent to Treatment of 360 Degrees With SLT? June 29, 2018 May 3, 2021
NCT03534882 Completed N/A Effects of Prostaglandin Analogue Washout Following Long-term Therapy in Adults With Primary Open Angle Glaucoma May 27, 2014 June 22, 2017
NCT03750201 Completed N/A A Study to Assess an Automated Laser Device for Direct Selective Laser Trabeculoplasty October 19, 2018 May 22, 2022
NCT03808688 Completed Phase 4 Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting December 27, 2018 July 26, 2019
NCT03825380 Completed Phase 3 Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous Patients November 23, 2018 February 24, 2021
NCT03844945 Completed Phase 2 Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan March 19, 2019 September 19, 2019
NCT03901781 Completed Phase 1 Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects October 23, 2019 May 20, 2022
NCT03926975 Completed N/A The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width June 1, 2018 August 30, 2019
NCT03960866 Completed Phase 2 Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma May 28, 2019 September 11, 2019
NCT04024072 Completed Phase 3 To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes June 24, 2019 April 30, 2020
NCT04035239 Completed Phase 1 Retinal Effects of Balance Goggles System in Glaucoma Balance Goggles System (BGS) in Patients With Glaucoma July 23, 2019 March 28, 2022
NCT04149899 Completed Phase 1/Phase 2 Safety and IOP-Lowering Effects of WB007 November 14, 2019 December 14, 2022
NCT04202562 Completed N/A Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual Blade February 2, 2017 November 30, 2018
NCT04284514 Completed Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solution May 2, 2019 December 15, 2019
NCT04285580 Completed Phase 3 A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension June 11, 2020 May 14, 2022
NCT04335825 Completed N/A Surgical and Refractive Outcomes of Combined Glaucoma Surgery January 1, 2016 December 30, 2019
NCT04360174 Completed Phase 1 CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension April 25, 2018 May 24, 2021
NCT04401982 Completed Measuring the Effects of Rhopressa on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects March 15, 2021 February 22, 2022
NCT04405245 Completed Phase 2 Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma June 6, 2020 November 5, 2020
NCT04445519 Completed Phase 3 Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension June 1, 2020 September 16, 2022
NCT04620135 Completed Phase 3 Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension November 30, 2020 July 30, 2021
NCT04654611 Completed Phase 4 Tafluprost Preservative Free Switch Study February 1, 2019 February 1, 2020
NCT04695314 Completed N/A Foot Reflexology in Ocular Hypertensive and Glaucoma Patients November 7, 2017 November 18, 2020
NCT04742283 Completed Phase 2 Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension December 17, 2020 December 7, 2021
NCT04743622 Completed Phase 4 Comparison of Efficacy and Ocular Surface Disease Assessment Between Monoprost and BAK-preserved Latanoprost April 30, 2019 September 13, 2020
NCT04747808 Completed Phase 2 Study of LL-BMT1 in Patients With Elevated Intraocular Pressure January 8, 2021 February 16, 2021
NCT04830397 Completed Phase 2 Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension). March 31, 2021 February 17, 2022
NCT04910100 Completed Phase 2 Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension April 15, 2021 April 29, 2022
NCT04911387 Completed iCare® Home vs Goldmann Applanation Tonometry April 1, 2020 October 31, 2020
NCT04944290 Completed Phase 3 To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes May 28, 2021 June 21, 2022
NCT04947124 Completed Phase 2 A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101 October 19, 2021 August 1, 2022
NCT04972695 Completed Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc Images May 7, 2021 February 23, 2022
NCT05022004 Completed Phase 3 A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension December 20, 2021 January 6, 2023
NCT05181046 Completed N/A Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients November 6, 2021 December 19, 2022
NCT05333419 Completed Phase 1 Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension. March 4, 2022 September 30, 2023
NCT05397600 Completed Phase 3 Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients June 22, 2022 March 7, 2024
NCT05495269 Completed Phase 2 Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP) November 23, 2022 March 20, 2023
NCT06144918 Completed Phase 2 Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure November 9, 2023 February 22, 2024
NCT00781300 Completed Phase 4 Intraocular Pressure With Loteprednol and Dexamethasone March 2006 February 2007
NCT00798759 Completed Phase 4 Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN December 2008 May 2009
NCT00800267 Completed Phase 3 A Study of Glaucoma or Ocular Hypertension in Patients Within the United States July 1997 June 1999
NCT00803387 Completed Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative April 2008 September 2008
NCT00803998 Completed Ocular Hypertension Treatment Study (OHTS) February 1994 December 2006
NCT00804648 Completed Phase 4 Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension November 2008 December 2008
NCT00809848 Completed Phase 1/Phase 2 Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma February 2009 May 2009
NCT00811564 Completed Phase 4 An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension Subjects December 2008 January 2010
NCT00820300 Completed Phase 2 A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma January 2009 December 2009
NCT00821002 Completed Phase 2 A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS) January 2009 November 2009
NCT00822055 Completed Phase 4 Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension May 2005 November 2006
NCT00822081 Completed Phase 4 Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension January 2005 April 2006
NCT00823043 Completed A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With 2 Drugs January 2009 July 2009
NCT00824720 Completed Phase 2 Safety and Efficacy of a Glaucoma Drug Delivery System December 2008 April 2009
NCT00825396 Completed N/A An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension April 2007 April 2009
NCT00828906 Completed Phase 4 DuoTrav® Eye Drops As Replacement Therapy Program February 2009
NCT00834171 Completed A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/Tobramycin January 2009 December 2009
NCT00838721 Completed N/A Evaluation of Pascal Laser Trabeculoplaty March 2008 March 2010
NCT00845299 Completed Phase 2 Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma January 2009 December 2009
NCT00846989 Completed Phase 1/Phase 2 Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension January 2009 April 2009
NCT00847483 Completed Phase 4 Comparison of Latanoprost With Travoprost and Bimatoprost in Patients With Elevated IOP. A 12-weeks, Masked Evaluator, Phase IV Multi-center Study in the US January 2002 August 2002
NCT00848536 Completed Phase 3 Efficacy Study of Travoprost APS Versus TRAVATAN March 2009 January 2010
NCT00856622 Completed Phase 3 A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients August 1997 June 1999
NCT00868894 Completed Phase 1/Phase 2 Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension March 2009 June 2010
NCT00872651 Completed Phase 3 Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension January 2010 November 2011
NCT00878917 Completed Phase 3 Equivalence Study of Dorzolamide 2% Eye Drops Solution April 2009 February 2010
NCT00887029 Completed Phase 4 A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma January 2009 November 2009
NCT00892762 Completed Phase 3 Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health June 2009 May 2011
NCT00918346 Completed Phase 3 Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation September 2005 April 2006
NCT00928590 Completed Phase 3 Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension July 2009 November 2010
NCT00934089 Completed Phase 2 A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329 January 2010 June 2010
NCT00941096 Completed Phase 4 Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination July 2009 November 2010
NCT00941525 Completed Phase 4 Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure September 2009 July 2014
NCT00945958 Completed Phase 3 Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension November 2010 June 2012
NCT00947661 Completed Phase 3 Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension July 2010 May 2012
NCT00950690 Completed Efficacy and Tolerability of Xalatan in Patients July 2005 December 2007
NCT00967811 Completed Phase 2 A Study of Different Formulations of the L-PPDS in Subjects With OH or OAG August 2009 May 2010
NCT00990743 Completed Phase 1 Tolerance and Effect on Intraocular Pressure After Administration of SYL040012 September 2009 June 2010
NCT01001195 Completed Phase 2 Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution November 2009 April 2010
NCT01012245 Completed Non-Interventional Study In Patients With Ocular Hypertension And Open Angle Glaucoma Treated With Xalatan And Xalacom January 2000 December 2008
NCT01016691 Completed Phase 2 Safety and Efficacy of a Drug Delivery System in Glaucoma October 2009
NCT01026831 Completed Phase 3 Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED) January 6, 2010 September 17, 2010
NCT01028664 Completed N/A Use of an Ocular Telemetry Sensor in Diamox Treated Patients December 2009 October 2010
NCT01033422 Completed Phase 2 Safety and Efficacy of Daily CF101 Administered Orally in Subjects With Elevated Intraocular Pressure October 2010 April 2017
NCT01037036 Completed Phase 2 A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG December 2009 July 2010
NCT01062971 Completed Phase 2 Clinical Study of A Fixed Combination of Timolol-Brimonidine-Dorzolamide February 2006 June 2008
NCT01068964 Completed N/A Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension February 1, 2010 September 1, 2010
NCT01087671 Completed Phase 3 Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops April 2010 October 2010
NCT01092273 Completed Bimatoprost Versus Travoprost at Cairo University
NCT01099774 Completed Phase 3 Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension May 1, 2010 April 29, 2011
NCT01110499 Completed Phase 2 Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension June 2010 June 2011
NCT01111890 Completed Phase 4 Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension April 2010 July 2011
NCT01114893 Completed Phase 2 Travoprost Five Day Posology Study April 2010
NCT01123785 Completed Phase 1/Phase 2 A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma May 2010 January 2012
NCT01126203 Completed Phase 3 Randomized Prospective Study of Selective Laser Trabeculoplasty (SLT) Versus Argon Trabeculoplasty (ALT) in Patients With Pseudoexfoliation Glaucoma and Ocular Hypertension September 2006 October 2009
NCT01157364 Completed Phase 1/Phase 2 Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension September 23, 2010 August 9, 2016
NCT01162603 Completed Phase 4 Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) March 2011 April 2012
NCT01168414 Completed Phase 3 A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension August 2010 February 2011
NCT01170884 Completed Phase 4 Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan® December 2009 September 2010
NCT01177098 Completed Phase 3 Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension October 2010 February 2012
NCT01191008 Completed Long Term Use Of Xalacom In Patients Glaucoma Or Ocular Hypertension October 2010 May 2015
NCT01206361 Completed Real World Data Study Assessing The Persistency Of Xalacom And The Other Fixed Dose Combination Products, Duotrav And Ganfort, In The United Kingdom February 2010 August 2010
NCT01210963 Completed Central Corneal Thickness With SENSIMED Triggerfish September 2010 February 2011
NCT01215786 Completed Phase 1 Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma October 2010 December 2010
NCT01216943 Completed Phase 3 Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertension November 2010 August 2012
NCT01217606 Completed Phase 3 Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension January 2011 June 2015
NCT01227291 Completed Phase 1/Phase 2 SYL040012. Tolerance and Effect on Intraocular Pressure in Subjects With Intraocular Pressure (IOP) >= 21 mm Hg October 2010 September 2012
NCT01229462 Completed N/A Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension October 2010 September 2011
NCT01229982 Completed Phase 2 A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma October 2010 August 2011
NCT01241240 Completed Phase 3 Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension March 2011 September 2013
NCT01253902 Completed Phase 4 Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension December 2010 October 2011
NCT01254370 Completed Phase 2 Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Disease November 2010 June 2011
NCT01254604 Completed Phase 3 Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002) December 1, 2011 May 9, 2013
NCT01261871 Completed Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning December 2008 May 2010
NCT01263444 Completed Phase 4 Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy March 2011 April 2013
NCT01265719 Completed Long-Term Non-Interventional Latanoprost Study December 2010 February 2016
NCT01271686 Completed Phase 4 24-hour IOP-lowering Effect of 0.01% Bimatoprost January 2011 October 2012
NCT01279083 Completed Phase 1/Phase 2 Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertension January 2011 February 2012
NCT01281020 Completed Adherence With Fixed Versus Unfixed Glaucoma Therapy May 2009 July 2011
NCT01291108 Completed Phase 2 Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension April 2011 October 2011
NCT01292460 Completed Phase 3 Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies February 2011 September 2012
NCT01297517 Completed Phase 3 Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2% February 2011 March 2012
NCT01297920 Completed Phase 3 Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2% March 2011 June 2012
NCT01298687 Completed Phase 2 Divided Dose of TRAVATAN® February 2011 April 2011
NCT01298700 Completed Phase 4 Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension May 31, 2011 December 6, 2016
NCT01302249 Completed Phase 2 AR-12286 in Combination With Latanoprost February 2011 December 2011
NCT01306461 Completed Phase 3 Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations March 2011 May 2012
NCT01309204 Completed Phase 3 Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension May 2011 January 2013
NCT01310777 Completed Phase 3 Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension May 2011 January 2013
NCT01327599 Completed Phase 4 Efficacy of Changing to DUOTRAV® From Prior Therapy August 2011 November 2012
NCT01330979 Completed Phase 2 24-hour Efficacy of AR-12286 May 2011 August 2012
NCT01340014 Completed Phase 4 Patient Preference Comparison of AZARGA Versus COSOPT September 2011 October 2012
NCT01342081 Completed Phase 3 DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5% May 2011
NCT01342094 Completed Phase 3 DE-111 Against Timolol Ophthalmic Solution 0.5% May 2011
NCT01357616 Completed Phase 3 Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension November 2010 January 2013
NCT01369771 Completed Phase 4 The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma August 2010 June 2012
NCT01379144 Completed Phase 2 A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension January 2003 April 2003
NCT01410188 Completed Phase 1/Phase 2 Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension September 2011 October 2012
NCT01415401 Completed Phase 4 Efficacy and Tolerability of AZARGA® as Replacement Therapy in Patients on COMBIGAN® Therapy in Canada September 2011 June 2013
NCT01426867 Completed Phase 2 A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2% September 2011 November 2011
NCT01453855 Completed Phase 3 Travoprost 3-Month Safety and Efficacy Study November 2011 August 2012
NCT01464424 Completed Phase 4 Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular Hypertension Treated With Travoprost 0.004% (TRAVATAN® Z) or Bimatoprost 0.01% (LUMIGAN®) October 2011 June 2012
NCT01474135 Completed Phase 2 AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure December 2011 April 2012
NCT01489670 Completed Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular Hypertension September 2011 March 2013
NCT01491867 Completed N/A Continuous Intraocular Pressure (IOP) Measurement and Ability to Detect Treatment Effect December 2011 October 2012
NCT01493427 Completed Phase 4 Efficacy of Changing to TRAVATAN® From Prior Therapy December 2011 February 2013
NCT01510145 Completed Phase 4 Efficacy of Changing to TRAVATAN® From Prior Therapy February 2012 May 2013
NCT01525173 Completed Phase 4 A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular Hypertension January 2012 October 2012
NCT01528111 Completed Phase 1/Phase 2 Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension March 2012 June 2012
NCT01528787 Completed Phase 2 Study of AR-13324 in Patients With Elevated Intraocular Pressure March 2012 July 2012
NCT01540370 Completed Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT) February 2012 July 2012
NCT01547598 Completed Phase 4 Safety and Efficacy of LUMIGAN® RC Versus DuoTrav® in Patients Who Require Further Intraocular Pressure (IOP) Reduction December 2011 July 2013
NCT01568008 Completed Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) October 2011 September 2012
NCT01589510 Completed A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) April 2012 February 2013
NCT01594970 Completed Phase 4 A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH) March 2012 January 2013
NCT01628588 Completed Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) March 2010 December 2010
NCT01628601 Completed GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to Monotherapy May 2010 June 2011
NCT01628614 Completed A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) November 2010 July 2011
NCT01632423 Completed A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) February 2010 November 2010
NCT01637246 Completed A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to Monotherapy April 2009 November 2011
NCT01646151 Completed A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension May 2012 April 2013
NCT01655758 Completed Phase 4 24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension January 2002 February 2004
NCT01658839 Completed Phase 1 Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients January 2013 July 2013
NCT01664039 Completed Phase 4 An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN® September 2012 June 2014
NCT01668524 Completed Phase 2 ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects August 2012 August 2012
NCT01693315 Completed Phase 2 Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucoma September 2012 July 2013
NCT01699464 Completed Phase 2 A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months October 2012 April 2013
NCT01707381 Completed Phase 2 BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension November 2012 February 2014
NCT01731002 Completed Phase 2 Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure November 2012 May 2013
NCT01735214 Completed An Observational Study of Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) Who Switched IOP-lowering Treatments March 7, 2013 April 10, 2014
NCT01739244 Completed Phase 2 Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma July 2012 May 2013
NCT01749904 Completed Phase 3 Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension January 31, 2013 September 30, 2015
NCT01749930 Completed Phase 3 Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension January 2013 May 2015
NCT01779778 Completed Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure April 2012 April 2013
NCT01789736 Completed Phase 2 A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days February 2013 June 2013
NCT01814761 Completed A Study of Bimatoprost 0.01% in the Clinical Setting May 2013 August 2014
NCT01830140 Completed Phase 3 A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension July 2013 May 2014
NCT01833741 Completed Phase 4 A Study of LUMIGAN® RC in the Clinical Setting December 2009 March 2011
NCT01853085 Completed A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical Reasons April 1, 2013 March 1, 2014
NCT01863953 Completed Phase 2 A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular Hypertension June 2013 December 2013
NCT01864642 Completed N/A Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect Subjects July 2013 June 2014
NCT01881126 Completed Phase 4 An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension June 2013 October 2014
NCT01895972 Completed Phase 3 Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024% in Japanese Subjects With OAG or OHT July 5, 2013 April 14, 2015
NCT01896180 Completed Phase 2 Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost July 2013 January 2014
NCT01915940 Completed Phase 2 Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension October 23, 2013 November 14, 2014
NCT01936389 Completed Phase 2 A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma September 2013 October 2014
NCT01937299 Completed Phase 4 Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z® October 2013 April 2014
NCT01937312 Completed Phase 4 Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue October 2013 May 2014
NCT01943721 Completed Phase 1 A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension October 2013 June 2014
NCT01975714 Completed Phase 4 Intraocular Pressure and Tolerability Study of Preservative-free Prostaglandins (Bimatoprost and Latanoprost) on Glaucoma and Ocular Hypertension: European, Multicentric, Investigator-led, Single Masked Study October 2013 February 2015
NCT01976624 Completed Safety and Efficacy of Bimatoprost/Timolol (Ganfort®) Ophthalmic Solution in Korea August 2009 January 2014
NCT01978600 Completed Phase 4 Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension October 2013 March 2014
NCT01979913 Completed Phase 4 An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in Patients With Ocular Hypertension or Primary Open Angle Glaucoma With an Uncontrolled Intraocular Pressure of 30 mmHg and More October 2013 September 2014
NCT01987323 Completed Phase 1/Phase 2 Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertension January 2013 June 2013
NCT01987752 Completed Safety and Efficacy of Combigan® Ophthalmic Solution in Korea January 2009 November 2011
NCT01995136 Completed Phase 4 Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucoma September 2013 June 2014
NCT01999348 Completed A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical Setting November 25, 2013 December 19, 2014
NCT02003391 Completed Phase 4 Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressure December 2013 May 2015
NCT02003534 Completed Phase 4 A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertension July 2010 February 2013
NCT02003547 Completed Phase 1 A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjects September 2013 December 2013
NCT02014142 Completed Phase 2 A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma December 2013 December 2016
NCT02017327 Completed Phase 4 Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose December 2013 July 2016
NCT02020512 Completed Phase 4 A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension July 2011 December 2012
NCT02057575 Completed Phase 2 Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure January 2014 June 2014
NCT02059278 Completed Phase 3 Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension January 2014 January 2015
NCT02061683 Completed Phase 4 A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension April 19, 2010 June 24, 2011
NCT03891446 Enrolling by invitation Phase 3 Long-term Safety and Efficacy Extension Trial of Bimatoprost SR March 27, 2019 August 7, 2026
NCT05159960 Enrolling by invitation N/A Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial January 10, 2022 November 30, 2025
NCT06266351 Not yet recruiting EVALUATION OF CATS TONOMETER PRISM IN LASIK SUBJECTS February 12, 2024 August 1, 2024
NCT06441643 Not yet recruiting Phase 2 Next Generation Rocklatan September 2024 November 2025
NCT06455683 Not yet recruiting The A D A G I O Study June 2024 June 2029
NCT06267274 Not yet recruiting Phase 1 A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes April 1, 2024 May 1, 2025
NCT06394973 Not yet recruiting Phase 2 Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension July 2024 May 2025
NCT05248139 Not yet recruiting N/A Safety and Effectiveness of Drop-free Small Incision Cataract Surgery October 2022 February 2023
NCT06177678 Not yet recruiting Phase 2 A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertension February 2024 September 2024
NCT04024293 Not yet recruiting N/A Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry November 2023 March 2024
NCT05844384 Recruiting N/A Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial March 17, 2022 March 17, 2024
NCT06152861 Recruiting Phase 2 Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension November 15, 2023 August 2024
NCT05039684 Recruiting Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical Prostaglandins October 1, 2021 December 2023
NCT04630808 Recruiting Phase 3 MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension November 9, 2020 September 2025
NCT05277870 Recruiting N/A Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular Hypertension February 28, 2022 June 30, 2025
NCT04524416 Recruiting MINIject Global Long-Term Follow-up Study August 5, 2020 December 2025
NCT05273385 Recruiting N/A Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma October 10, 2022 December 10, 2024
NCT04500574 Recruiting Phase 1 Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension April 3, 2023 December 2023
NCT05857267 Recruiting Phase 4 Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safety March 7, 2023 November 15, 2024
NCT04647214 Recruiting 18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA) March 3, 2021 July 23, 2024
NCT05401357 Recruiting Phase 3 Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes. June 29, 2022 December 2022
NCT05913232 Recruiting Phase 2 Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension August 28, 2023 December 2025
NCT04499248 Recruiting Phase 1/Phase 2 AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension November 16, 2020 August 30, 2027
NCT06120842 Recruiting Phase 1/Phase 2 Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution October 13, 2023 June 2027
NCT04957329 Recruiting Phase 4 Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells September 1, 2021 December 31, 2026
NCT04761705 Suspended Phase 1/Phase 2 Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension March 10, 2021 July 2025
NCT00767494 Terminated Phase 3 Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPT October 2008 February 2009
NCT02858284 Terminated N/A Evaluation of Safety and Efficacy of TUG (Therapeutic Ultrasound for Glaucoma) in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension July 1, 2016 August 22, 2018
NCT02730871 Terminated Phase 4 Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV® June 24, 2016 July 13, 2018
NCT02801617 Terminated Phase 3 Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension September 2015 July 19, 2017
NCT02030886 Terminated N/A IOP Patterns in Ocular Hypertensive Patients Newly Converted to Glaucoma vs Stable Ocular Hypertensive Patients December 2013 June 2015
NCT00047606 Terminated Phase 4 Phase 4 Study Comparing IOP Lowering in OAG or OH in Caucasian or Japanese Subjects C-02-32 August 2002 November 2003
NCT02047630 Terminated Phase 4 Efficacy of the Brand-name Latanoprost and One of Its Generic Version in Primary Open Angle Glaucoma and Ocular Hypertension January 2014 December 4, 2014
NCT04442464 Terminated N/A Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear July 1, 2020 August 27, 2020
NCT00047554 Terminated Study of TRAVATAN in Subjects With Iris Pigmentation Changes May 2003 June 2012
NCT01312454 Terminated Phase 2 Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412C June 2011 January 2012
NCT01719809 Terminated An Evaluation of the Ability to Train Established Glaucoma Patients Who Have Difficulty in Drop Instillation October 2012 June 1, 2015
NCT00912054 Terminated Phase 3 DuoTrav APS Versus XALACOM® in Ocular Surface Health March 2010 May 2011
NCT02891317 Terminated Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma May 8, 2017 June 12, 2017
NCT04702789 Terminated Phase 4 Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension. October 19, 2021 November 23, 2023
NCT00788541 Terminated Phase 2 A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertension December 2008 September 2009
NCT00767481 Terminated Phase 3 1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT October 2008 February 2009
NCT00961649 Terminated Phase 2 Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combination October 2009 February 2010
NCT01781962 Terminated A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular Hypertension January 2013 June 2013
NCT01864317 Terminated Phase 2 Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging November 2015 December 2015
NCT00471068 Terminated Phase 4 Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertension March 2007
NCT05279716 Unknown status Phase 4 Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl February 15, 2022 November 20, 2023
NCT03067415 Unknown status Phase 2 Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily March 30, 2017 September 30, 2017
NCT00804115 Unknown status N/A The International Collaborative Exfoliation Syndrome Treatment Study August 2000 December 2008
NCT01361841 Unknown status N/A Effects of Latanoprost, Bimatoprost and Travoprost in Patients With Latanoprost-resistant Glaucoma January 2009 January 2013
NCT03318146 Unknown status N/A Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LP June 1, 2018 September 1, 2019
NCT01430923 Unknown status N/A Clinical Evaluation of Safety and Efficacy of Refrigeration Free Latanoprost September 2011 August 2012
NCT04863365 Unknown status Phase 3 A Study of Efficacy and Safety of PHP-201 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension November 2021 November 2023
NCT01467388 Unknown status Efficacy of Selective Laser Trabeculoplasty in Pseudophakic Patients November 2011 December 2015
NCT01467440 Unknown status Efficacy of Selective Laser Trabeculoplasty in Patients Under Treatment With Topical Prostaglandines November 2011 December 2015
NCT00744666 Unknown status Phase 4 IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids September 2008 July 2010
NCT04891588 Unknown status N/A Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD March 8, 2021 December 8, 2021
NCT03584958 Unknown status Comparing Refractive and Visual Outcomes of MIGS and Traditional Surgeries August 1, 2018 June 30, 2023
NCT01520116 Unknown status Phase 1/Phase 2 Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertension January 2012
NCT03762369 Unknown status Phase 3 A Clinical Study to Evaluate the Efficacy and Safety of CKD-351 December 7, 2018 May 30, 2022
NCT00567411 Unknown status N/A Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty August 2006 June 2009
NCT00494923 Unknown status Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma January 1999 December 2020
NCT00476138 Unknown status Phase 1/Phase 2 Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early Glaucoma November 2006 July 2008
NCT03870230 Unknown status N/A Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects December 1, 2017 March 2023
NCT02379208 Unknown status Evaluation of Rate of Progression With Perimetry in Newly Diagnosed Open Angle Glaucoma April 2015 May 2020
NCT01084902 Unknown status N/A Efficacy Comparison of Xalatan and Azopt on POAG and OH February 2010 December 2010
NCT02394613 Unknown status Phase 1 A Phase I Clinical Trial of DARC May 2015 August 2016
NCT00347893 Unknown status The Efficacy of Selective Laser Trabeculoplasty May 2006
NCT02471105 Unknown status Phase 4 Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/ml September 2015 December 2017
NCT05241938 Unknown status N/A PSLT Compared to Prostaglandin Analogue Eye Drops September 1, 2021 December 20, 2022
NCT02585375 Unknown status Phase 4 Latanoprost Preserved Versus Unpreserved: Effect on Tear Film Thickness as Measured With OCT September 17, 2015 September 2, 2023
NCT05299593 Unknown status Phase 4 24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration. June 4, 2020 June 30, 2022
NCT01886456 Unknown status N/A IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients February 2013 February 2017
NCT04448223 Unknown status Phase 2 A Clinical Study to Evaluate the Efficacy and Safety of CKD-351 June 11, 2020 December 5, 2022
NCT02792803 Unknown status Phase 4 A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucoma September 2015 September 2017
NCT02839590 Unknown status Aqueous Dynamics and Glaucoma Surgeries July 2016 December 2017
NCT04585100 Unknown status Phase 1/Phase 2 FM101 Safety, Tolerability, Efficacy Study in the Patients With Ocular Hypertension October 7, 2020 June 30, 2023
NCT04595227 Unknown status Glaucoma Screening Using Dynamic Analysis of Computerized Pupillary Light Reflex Assessment Device October 30, 2020 October 1, 2021
NCT04609345 Unknown status Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients November 2020 May 2021
NCT01452009 Withdrawn Phase 3 Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004% November 2011 December 2011
NCT03927443 Withdrawn Phase 3 A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertension June 10, 2019 July 8, 2019
NCT02295358 Withdrawn The Effect of Omega-3 Fatty Acid Supplementation on Intraocular Pressure & Ocular Surface November 2014 November 2015
NCT00283764 Withdrawn Phase 3 Safety And Efficacy Of Xalatan Delivered Using Either A Conventional Dropper Bottle or A Delivery Device
NCT01927406 Withdrawn Phase 4 The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients. June 2014 December 2016
NCT01446588 Withdrawn N/A Ocular Hypertension And Yoga Study June 2012 December 2012
NCT00815373 Withdrawn N/A The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG) December 2008 June 2012
NCT01510132 Withdrawn Phase 4 Travacom Post Marketing Surveillance Study January 2012 January 2012
NCT00862472 Withdrawn Phase 3 Safety and Efficacy Study of DuoTrav APS Versus DuoTrav March 2009 June 2009
NCT00143429 Withdrawn Phase 2 Corneal Versus Conjunctival Delivery Using a Delivery Device
NCT04140279 Withdrawn Phase 4 A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension May 13, 2022 August 2023
NCT01721707 Withdrawn Phase 3 Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OH December 2012 June 2013
NCT01284166 Withdrawn Phase 3 Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension July 2013 May 2014
NCT01696383 Withdrawn Phase 4 Assessing the Efficacy of DuoTrav as a Replacement Therapy in Glaucoma Patients in Russia February 2013 February 2013
NCT02623023 Withdrawn N/A Prophylaxis for Anti-VEGF-induced IOP Elevation January 1, 2019 January 1, 2019
NCT00855517 Withdrawn Phase 2 A Phase 2 Study of the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma March 2009 July 2009
NCT05043831 Withdrawn N/A Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population The Zhuiguang Trial October 15, 2021 April 15, 2023
NCT04005079 Withdrawn Phase 3 Pilocarpine After Combined Cataract/Trabectome Surgery June 5, 2019 January 21, 2021
NCT04433702 Withdrawn N/A Effect of Negative Pressure on Pattern Electroretinography Readings October 1, 2020 December 2020
Disase is a (Disease Ontology)
DOID:5614
Cross Reference ID (Disease Ontology)
ICD10CM:H40.05
Cross Reference ID (Disease Ontology)
ICD9CM:365.04
Cross Reference ID (Disease Ontology)
MESH:D009798
Cross Reference ID (Disease Ontology)
NCI:C3285
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:267721003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0028840
MeSH unique ID (MeSH (Medical Subject Headings))
D009798