endocarditis

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Information
Disease name
endocarditis
Disease ID
DOID:10314
Description
"A endocardium disease characterized by inflammation of the endocardium of the heart chambers and valves." [url:http\://en.wikipedia.org/wiki/Endocarditis, url:http\://www.nhlbi.nih.gov/health/health-topics/topics/endo/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06434012 Active, not recruiting Barts Endocarditis Research Registry April 24, 2019 April 30, 2029
NCT00548002 Completed Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia January 1999 August 2002
NCT03695861 Completed N/A Contribution of 18F-FDG PET-CT in the Diagnosis and the Detection of Peripheral Emboli of Infectious Endocarditis on Native Valves November 10, 2018 September 16, 2020
NCT04309591 Completed Cytosorb Therapy in Cardiac Surgery October 18, 2019 December 4, 2019
NCT04068337 Completed Freestyle Prosthesis for Aortic Root-replacement With and Without Hemiarch Replacement August 1, 2018 August 1, 2019
NCT03377465 Completed N/A Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis November 15, 2016 December 5, 2017
NCT00709358 Completed Phase 4 Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections May 2008 September 2010
NCT00750373 Completed Phase 4 Early Surgery Versus Conventional Treatment in Infective Endocarditis September 2006 September 2011
NCT00166023 Completed Outcomes Following Medical or Surgical Management of Endocarditis August 2005 December 2006
NCT01375257 Completed Phase 4 Partial Oral Treatment of Endocarditis July 2011 August 30, 2017
NCT01431326 Completed Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care November 2011 November 2019
NCT05474118 Completed Real-life Use of Cefazolin for the Treatment of Meticillin-susceptible Staphylococcal Infective Endocarditis: Comparison to a Treatment Cohort With Penicillin M February 5, 2020 March 31, 2022
NCT02026895 Completed N/A Virulence of Staphylococcus Lugdunensis in Severe Infections December 2013 February 2016
NCT02251262 Completed N/A Diagnostic Accuracy of 18FDG-PET-CT for Pacing or Defibrillation Lead Infection June 22, 2015 June 19, 2018
NCT04387513 Completed Impact of Early Cardiac Surgery in Severe Left Endocarditis With Neurological Complications: a Retrospective Study August 1, 2010 December 31, 2017
NCT05156437 Enrolling by invitation Phase 4 Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) March 16, 2022 October 2024
NCT06422221 Not yet recruiting Phase 4 An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures July 15, 2024 June 30, 2025
NCT05613933 Not yet recruiting N/A Effectiveness of Antibiotic Prophylaxis of Infective Endocarditis for Invasive Dental Procedures in Patients With Prosthetic Heart Valves and/or History of Infective Endocarditis February 1, 2023 December 31, 2027
NCT06107309 Recruiting Suppressive Antibiotic Therapy for Endocarditis March 1, 2023 March 2024
NCT03718052 Recruiting N/A Early Valve Surgery Versus Conventional Treatment in Infective Endocarditis Patients With High Risk of Embolism April 11, 2019 April 11, 2026
NCT03892174 Recruiting N/A Cytokine REmoval in CRitically Ill pAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE) November 14, 2019 December 1, 2024
NCT05139589 Recruiting The ENDOCARDITIS AUMC Data Collection August 6, 2023 December 31, 2030
NCT05144399 Recruiting Phase 4 Accelerated Treatment of Endocarditis April 1, 2019 December 31, 2026
NCT05146180 Recruiting N/A Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis February 24, 2022 March 1, 2024
NCT05378126 Recruiting N/A Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious Endocarditis April 6, 2023 July 2025
NCT05432427 Recruiting N/A 64Cu-DOTATATE PET-CT-skanning and Infective Endocarditis. April 28, 2022 June 1, 2025
NCT05547607 Recruiting Clinical and Diagnostic Features of Endocarditis September 9, 2022 September 30, 2025
NCT05703022 Recruiting N/A Early Exercise Training in Patients Following Heart Valve Surgery for Infective Endocarditis. November 30, 2021 June 30, 2025
NCT06275100 Recruiting N/A PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry April 3, 2024 June 2025
NCT06330766 Recruiting Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients January 1, 2020 January 1, 2026
NCT06403839 Recruiting Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients January 1, 2020 March 1, 2028
NCT03148756 Terminated Phase 2 Efficacy and Safety of Dalbavancin Compared to Standard of Care Antibiotic Therapy for the Completion of Treatment of Patients With Complicated Bacteremia or Infective Endocarditis May 12, 2017 August 4, 2017
NCT03411499 Terminated N/A Stroke-free Survival Comparison Between Early Surgery and Conventional Therapy in Left Infective Endocarditis December 22, 2017 December 14, 2020
NCT00590889 Terminated N/A Artificial Valve Endocarditis Reduction Trial July 1998 September 2014
NCT00995384 Terminated N/A Cardiac Computed Tomography (CT) Scan Compared to Transesophageal Echocardiogram (TEE) in Endocarditis October 2009 October 2010
NCT02783404 Terminated Phase 4 An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures February 27, 2017 May 17, 2022
NCT01734694 Terminated Phase 4 Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients October 2011 September 2012
NCT02459613 Terminated Phase 1/Phase 2 Assessment of Radiolabeled rhAnnexin V-128 in Infective Endocarditis February 5, 2016 May 2017
NCT02759978 Unknown status Individualized Diagnosis of Endocarditis and Its Therapy With a Focus on Infected Prosthetic materiAL May 2016 May 2023
NCT03690076 Unknown status Human Cardiac Mitochondria in Acute Endocarditis and Obesity October 9, 2018 September 30, 2020
NCT01301638 Unknown status Retrospective Evaluation of Safety and Efficacy of Daptomycin Used in Patients With Serious Gram-positive Infections February 2011
NCT02443064 Unknown status Phase 4 Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycin January 2014 June 2016
NCT03231449 Unknown status A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa February 1, 2017 February 2021
NCT03429153 Unknown status Management of Infectious Endocarditis as Part of a Multidisciplinary Consensus Meeting January 5, 2018 August 2018
NCT05142891 Unknown status Renal Tolerance of Amoxicillin and Cloxacillin Combination October 15, 2021 October 30, 2022
NCT03112356 Unknown status Phase 4 The Value of 99mTc-Leukoscan® Scintigraphy in the Diagnosis of Infectious Endocarditis on Surgical Materials June 14, 2017 October 14, 2018
NCT00579761 Withdrawn Retrospective Review of Management of Infective Endocarditis
Disase is a (Disease Ontology)
DOID:0050825
Cross Reference ID (Disease Ontology)
ICD10CM:I33.9
Cross Reference ID (Disease Ontology)
ICD9CM:421.9
Cross Reference ID (Disease Ontology)
MESH:D004696
Cross Reference ID (Disease Ontology)
NCI:C34582
Cross Reference ID (Disease Ontology)
NCI:C35432
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:56819008
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:91357005
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0014118
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0375268
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0100584
MedGen unique identifier (MedGen Concept name)
4940
MedGen concept unique identifier (MedGen Concept name)
C0014118
MeSH unique ID (MeSH (Medical Subject Headings))
D004696