Annotation Detail

Information
Associated Genes
MMP2
Associated Variants
MMP2 MUTATION
MMP2 MUTATION
Associated Disease
Malignant tumor of colon
Source Database
DisGeNET
Description
Here we report that forced GRP78 expression promotes colon cancer cell migration and invasion through upregulating MMP-2, MMP-9 and especially uPA production.
Pubmed
24314144
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00651460492992728
Drugs