Annotation Detail

Information
Associated Genes
MMP2
Associated Variants
MMP2 MUTATION
MMP2 MUTATION
Associated Disease
Congenital arteriovenous malformation
Source Database
DisGeNET
Description
Cultured AVMECs expressed higher angiogenic factors (VEGF, MMP-2) than the controlled BECs, implicating angiogenesis plays an important role in the pathogenesis of AVM.
Pubmed
24771337
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs