Annotation Detail
Information
- Associated Genes
- MMP2
- Associated Variants
-
MMP2 MUTATION
MMP2 MUTATION - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- In the present study, we demonstrate that green tea polyphenols (GTP) and its major constituent, epigallocatechin-3-gallate (EGCG) mediate epigenetic induction of TIMP-3 levels and play a key role in suppressing invasiveness and gelatinolytic activity of MMP-2 and MMP-9 in breast cancer cells.
- Pubmed
- 24481780
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0176437216852197
Drugs