Neuromuscular Diseases
Information
- Disease name
- Neuromuscular Diseases
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes | Mutation | Description | Source | Links |
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NCT ID | Status | Phase | Summary | Start date | Completion date |
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NCT05479981 | Active, not recruiting | Phase 2 | Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients | August 4, 2022 | June 2025 |
NCT05337553 | Active, not recruiting | Phase 3 | A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy | July 6, 2022 | January 2025 |
NCT05070624 | Active, not recruiting | N/A | The Peer Support Study | September 15, 2022 | December 30, 2024 |
NCT05206617 | Active, not recruiting | 3 Year Follow up on ANO5 Patients | January 1, 2018 | November 1, 2025 | |
NCT03355105 | Active, not recruiting | N/A | Comparison of Two Methods of Adjusting the Mechanical In-Exsuflation in Neuromuscular Adult Patients | March 7, 2019 | December 24, 2024 |
NCT03478566 | Active, not recruiting | N/A | Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease | October 1, 2018 | September 1, 2023 |
NCT03548779 | Active, not recruiting | N/A | North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 | September 28, 2018 | September 8, 2024 |
NCT05156320 | Active, not recruiting | Phase 3 | Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam | February 24, 2022 | December 2024 |
NCT05626855 | Active, not recruiting | Phase 3 | Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab-ONYX | April 17, 2023 | January 1, 2027 |
NCT01826487 | Completed | Phase 3 | Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | March 26, 2013 | August 20, 2015 |
NCT00002044 | Completed | N/A | A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases | ||
NCT05771727 | Completed | Impact of Covid-19 Pandemic on Children With Neuromuscular Disease and Their Parents in Turkey: Parent Perspective | July 1, 2021 | October 1, 2021 | |
NCT05730842 | Completed | Phase 1 | Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers | January 12, 2023 | April 6, 2023 |
NCT02208687 | Completed | N/A | Effectiveness and Cost-effectiveness of the Energetic Program | August 2014 | May 2017 |
NCT02242162 | Completed | Establishment of a Non-invasive and Indirect Measure of Volitional Pimax | May 2009 | January 2016 | |
NCT02342132 | Completed | N/A | Methods to Improve Expiratory Cough Flow and Lung Volume in Children With NMDs | August 2014 | February 2015 |
NCT02436096 | Completed | Phase 3 | A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia | April 2015 | September 2016 |
NCT02500030 | Completed | N/A | Air Stacking vs Glossopharyngeal Breathing in Neuromuscular Diseases | June 2013 | June 2014 |
NCT02743702 | Completed | N/A | Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease | June 2012 | December 2014 |
NCT02753959 | Completed | N/A | Changes in Regional Lung Ventilation Following Mechanical Insufflation-Exsufflation | August 1, 2016 | September 30, 2019 |
NCT05460156 | Completed | N/A | The Bridges Self-management Programme for People With Neuromuscular Diseases | February 14, 2022 | November 27, 2023 |
NCT02845362 | Completed | N/A | Validation of the French Version of the Sydney Swallow Questionnaire in Patients With Neuromuscular Diseases | August 2016 | October 2018 |
NCT05353738 | Completed | Efficacy of Vaccination Against COVID-19 in Patients Presenting a Neuromuscular Disease With Severe Amyotrophy | September 1, 2021 | September 1, 2022 | |
NCT05311904 | Completed | Efficacy and Safety of Vaccination Against COVID-19 in Neuromuscular Patients | March 11, 2021 | February 3, 2023 | |
NCT03085537 | Completed | Effectiveness Monitoring of Home Non-invasive Mechanical Ventilation by Digital Diagnosis Platform | October 1, 2016 | October 30, 2021 | |
NCT03127514 | Completed | Phase 2 | AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) | June 22, 2017 | November 24, 2019 |
NCT03179631 | Completed | Phase 3 | Long-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy | July 6, 2017 | July 25, 2023 |
NCT03203577 | Completed | N/A | Initiation of Home Mechanical Ventilation at Home in Patients With Chronic Hypercapnic Respiratory Failure | July 2015 | May 2018 |
NCT03218215 | Completed | Monitoring Mechanical Assisted Cough | May 1, 2015 | May 31, 2017 | |
NCT05239520 | Completed | Understanding Control and Mechanisms of Shoulder Instability in FSHD | March 25, 2022 | October 21, 2022 | |
NCT03289715 | Completed | N/A | Evaluation of an On-Demand Humidifier on Neuromuscular Patients Requiring Mechanical Ventilation | January 12, 2018 | July 31, 2018 |
NCT03312361 | Completed | N/A | Assessing Air Travel Safety in Neuromuscular Dystrophy: Standard Versus Prolonged High Altitude Simulation Tests | April 1, 2016 | April 1, 2018 |
NCT03394859 | Completed | Electronic Medical Records and Genomics (eMERGE) Phase III | September 1, 2015 | April 1, 2020 | |
NCT03406780 | Completed | Phase 2 | A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy | March 4, 2018 | March 10, 2020 |
NCT03440034 | Completed | Phase 1 | Study of Pioglitazone in Sporadic Inclusion Body Myositis | May 22, 2018 | December 31, 2020 |
NCT03445832 | Completed | Pulmonary Function and Neuromuscular Disease | January 8, 2018 | February 10, 2018 | |
NCT03458507 | Completed | N/A | Impact of the Type of Interface in Neuromuscular Patients Treated With Nocturnal Noninvasive Ventilation | May 28, 2018 | June 26, 2019 |
NCT03465358 | Completed | Validation of Completion of Items 18, 19 and 22 of the Motor Function Measure (MFM) on a Digital Tablet | March 14, 2018 | November 28, 2018 | |
NCT03506906 | Completed | N/A | The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation | November 11, 2018 | September 21, 2020 |
NCT05070910 | Completed | N/A | NDT Effectiveness Study | October 25, 2021 | March 31, 2022 |
NCT04473612 | Completed | Physical Status and Upper Airway Function in Neuromuscular Patients | July 20, 2020 | September 1, 2020 | |
NCT04435093 | Completed | Digitalization Playful Module of Motor Function Measure Assessment for Children With Neuromuscular Disorders, MFM-Play Pilot Study. | September 21, 2020 | March 4, 2021 | |
NCT00720161 | Completed | N/A | Metformin in Children With Motor Deficit | November 2006 | July 2011 |
NCT06031701 | Completed | N/A | Neuro-psychosocial Teleassistance for Neuromuscular Diseases | November 2, 2021 | June 30, 2023 |
NCT00942227 | Completed | Phase 3 | The Value of Traction in Treatment of Lumbar Radiculopathy | July 2009 | December 2012 |
NCT00979108 | Completed | Phase 3 | The Value of Traction in the Treatment of Cervical Radiculopathy | July 2009 | January 2013 |
NCT01022931 | Completed | Epidemiology and Clinical Presentation of H1N1 Infection in Children in Geneva | October 2009 | July 2012 | |
NCT01313325 | Completed | N/A | Hippotherapy to Improve the Balance of Children With Movement Disorders | September 2006 | December 2007 |
NCT01495390 | Completed | A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers | November 2011 | December 31, 2016 | |
NCT04652401 | Completed | Quality of Life in Ventilator-dependant Neuromuscular Patients | December 2, 2020 | December 7, 2021 | |
NCT04106154 | Completed | N/A | Impacting Children's Physical and Mental Health Through Kinesiology Support in Clinical Care | November 4, 2019 | December 31, 2022 |
NCT03623698 | Completed | Nebulised Hypertonic Saline in Children and Young People With Neuromuscular Disease and Cerebral Palsy | June 15, 2018 | September 26, 2019 | |
NCT03627962 | Completed | N/A | Oculomotor Training and Chinese Characters Recognition in Children With Neuromuscular Disease | November 1, 2016 | August 8, 2018 |
NCT03645031 | Completed | N/A | Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease | October 1, 2018 | June 2, 2023 |
NCT05021744 | Completed | Do Handgrip Strength and Dexterity Predict of Respiratory Function ? | December 13, 2014 | January 1, 2016 | |
NCT04935905 | Completed | Accuracy of Peak Cough Flow Measurements Using a Mechanical Insufflator-exsufflator | December 4, 2020 | September 1, 2021 | |
NCT03824223 | Completed | N/A | 'Fitness To Fly' Tests In Children With Type II Respiratory Failure | February 1, 2019 | August 31, 2021 |
NCT03831568 | Completed | Mechanical Cough Augmentation in Children With NMD | January 1, 2018 | January 31, 2019 | |
NCT03863496 | Completed | N/A | Efficacy of Surgical Treatment by Different Pedicle Screw Systems in Pediatric Neuromuscular Spinal Deformity | January 31, 2018 | February 14, 2021 |
NCT03867721 | Completed | N/A | Patient Preference for Mouthpiece Ventilation | January 1, 2015 | December 30, 2018 |
NCT03921528 | Completed | Phase 2 | An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy | April 22, 2019 | February 28, 2024 |
NCT04837157 | Completed | N/A | Evaluation of the Exoskeleton ATLAS 2030 as Robot-assisted Physical Therapy to Children With Neuromuscular Diseases | October 15, 2020 | January 31, 2021 |
NCT04813601 | Completed | N/A | Rehabilitative Effect of the Use of a Gait Exoskeleton in Patients With Neuromuscular Disease or Cerebral Palsy | March 9, 2020 | September 24, 2023 |
NCT04729920 | Completed | Home Use of Mechanical Insufflation/Exsufflation Devices in Neuromuscular Diseases | September 15, 2019 | May 1, 2020 | |
NCT06428864 | Completed | Effect of the Use of a 3D Scanner Application on a Smartphone to Mold Garchois Orthotic Device in Neuromuscular Diseases Patients With Scoliosis | September 1, 2023 | November 1, 2023 | |
NCT05099107 | Enrolling by invitation | N/A | Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment | October 25, 2021 | December 31, 2025 |
NCT05539456 | Enrolling by invitation | Reliability and Validity of the Turkish Version of the PedsQL 3.0 Neuromuscular Module for 2-to 4- Year-old | September 1, 2022 | November 1, 2022 | |
NCT05831514 | Not yet recruiting | N/A | Developing a Mobile Application for the Care of Children With Gastrostomy and The Effect of the Application on Gastrostomy | July 28, 2023 | August 28, 2024 |
NCT04089696 | Not yet recruiting | N/A | Validation of the "ExSpiron©" in Patients With ALS | September 2025 | September 2025 |
NCT04866459 | Not yet recruiting | MYO-SHARE: MYO-MRI in Neuromuscular Diseases | May 30, 2021 | May 30, 2031 | |
NCT05785546 | Not yet recruiting | Elaboration of a Pronostic Score of Changes on Wheelchair's Seating System | September 2024 | March 2028 | |
NCT06119087 | Not yet recruiting | N/A | Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study | June 1, 2024 | December 31, 2025 |
NCT06134401 | Not yet recruiting | N/A | Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability | April 2024 | December 2026 |
NCT06151600 | Not yet recruiting | A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J | March 1, 2024 | March 1, 2028 | |
NCT06367686 | Not yet recruiting | Detecting Systemic Carbon Dioxide Levels With a Novel Biosensor | May 2024 | December 2024 | |
NCT06379932 | Not yet recruiting | Pain and Muscle Biopsy | July 1, 2024 | December 1, 2024 | |
NCT06438965 | Not yet recruiting | MSOT as Non-invasive Biomarker for Diagnosis and Monitoring of Neuromuscular Diseases | July 2024 | July 2028 | |
NCT06084026 | Recruiting | Measuring Physical Activity With ActivPal | November 1, 2020 | August 2024 | |
NCT06259643 | Recruiting | N/A | Effects of Power Wheelchair Soccer for Individuals Presenting With Physical Impairments | November 1, 2023 | June 15, 2024 |
NCT03797183 | Recruiting | Genesis Electrical Impedance Tomography (EIT): A Preliminary Study | May 3, 2019 | November 30, 2024 | |
NCT05006859 | Recruiting | Wheelchair Positioning and Neuromuscular Diseases | May 17, 2021 | December 2024 | |
NCT05048862 | Recruiting | The Neuroimage Study of the Neuromuscular Disorders. | August 1, 2021 | August 1, 2031 | |
NCT05051254 | Recruiting | N/A | Respiratory Muscles and Work of Breathing in Children | January 19, 2022 | January 2028 |
NCT05126758 | Recruiting | Phase 3 | A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy | June 22, 2022 | December 2026 |
NCT05189600 | Recruiting | Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms? | January 1, 2022 | January 1, 2025 | |
NCT05318638 | Recruiting | N/A | Soft-robotic Glove Support of High-demand Tasks | October 17, 2022 | December 2024 |
NCT05328492 | Recruiting | N/A | Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis | March 15, 2022 | March 15, 2024 |
NCT05346263 | Recruiting | N/A | Efficacy of Intermittent Abdominal Pressure Ventilation in Neuromuscular Patients | March 1, 2022 | March 1, 2025 |
NCT02851043 | Recruiting | N/A | Non-Invasive Respiratory Monitor | August 2014 | September 2024 |
NCT05366010 | Recruiting | N/A | Oscillation and Lung Expansion (OLE) for Treatment of Neuromuscular Disease Patients | November 4, 2021 | April 2024 |
NCT05434572 | Recruiting | MDTRP Neuromuscular Research Biobank | March 17, 2021 | February 2030 | |
NCT02253290 | Recruiting | Neuropsychological and Psychosocial Follow up of Children and Adolescents With Neuromuscular Disease | December 2014 | April 2025 | |
NCT05544994 | Recruiting | N/A | The Effect of Aerobic Exercise Training in Patients With Type III Spinal Muscular Atrophy | July 28, 2022 | September 30, 2024 |
NCT05723289 | Recruiting | Evaluation of the Feasibility of Remote Monitoring of Mechanical In-exsufflation Devices in Paralytic and Neuromuscular Patients Treated at Home. | June 2023 | December 2023 | |
NCT06339580 | Recruiting | Phase 2 | Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease | April 9, 2024 | April 2026 |
NCT05785637 | Recruiting | Polygraphy at Home for Neuromuscular Patients Under Non-invasive Mechanical Ventilation | March 8, 2024 | March 2026 | |
NCT05798325 | Recruiting | N/A | Feasibility, Validation and Application of Digital Tools for the Follow-up of Neuromuscular Patient Mobility in Daily Living | June 29, 2023 | June 30, 2024 |
NCT06074822 | Recruiting | Research Biobank From Neuromuscular Biopsy Residues (in the Context of Care) | June 26, 2023 | June 25, 2053 | |
NCT06439823 | Recruiting | N/A | Controlled Study of Upper and Lower Limb Movements in Patients With Neurological Pathologies | August 24, 2022 | August 2028 |
NCT06381284 | Recruiting | Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment | March 28, 2024 | May 27, 2025 | |
NCT06190431 | Recruiting | N/A | Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects? | November 20, 2023 | December 31, 2024 |
NCT06207591 | Recruiting | N/A | Investigation on the Cortical Communication System | December 15, 2023 | October 2027 |
NCT06226376 | Recruiting | N/A | Mollii Suit and Fibromyalgia (EXOFIB 2) | January 8, 2024 | July 1, 2025 |
NCT04236726 | Recruiting | Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure | December 19, 2019 | May 31, 2025 | |
NCT04283175 | Recruiting | Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients | April 1, 2021 | April 1, 2024 | |
NCT04380649 | Recruiting | N/A | Development and Test of a Headset for BCI Until Obtaining an Efficient and Comfortable System That Can be Used in Daily Practice by ALS People | February 13, 2023 | February 2025 |
NCT04163198 | Recruiting | N/A | Optimisation of Mechanical Insufflation:Exsufflation | December 19, 2019 | May 31, 2025 |
NCT04541602 | Recruiting | Detection of Neuromuscular Complications in Critically Ill Patients | September 1, 2020 | March 31, 2023 | |
NCT03945968 | Recruiting | The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. | July 1, 2019 | February 28, 2025 | |
NCT03353064 | Terminated | N/A | Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure | October 18, 2017 | October 26, 2018 |
NCT03694431 | Terminated | N/A | Comparative Trial of Home-Based Palliative Care | January 7, 2019 | January 24, 2020 |
NCT02078050 | Terminated | N/A | Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures | November 2013 | May 2015 |
NCT04226144 | Terminated | N/A | Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients | January 6, 2020 | December 1, 2022 |
NCT02829814 | Terminated | Phase 3 | Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With Fibromyalgia | July 2016 | September 2016 |
NCT00839033 | Terminated | Phase 3 | Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders | June 2009 | December 2011 |
NCT02951572 | Terminated | N/A | Non-invasive Ventilation and Physical Activity | February 2013 | June 2017 |
NCT02090959 | Terminated | Phase 3 | An Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy | March 20, 2014 | June 12, 2018 |
NCT05122273 | Unknown status | Assessment of the Effectiveness of Muscle Activating Training With the Use of EMG Biofeedback in Patients With Neuromuscular Diseases | November 20, 2021 | February 28, 2022 | |
NCT02103790 | Unknown status | N/A | Installation of Non-invasive Ventilation at Home Using Telemedicine : a Pilot Study on Feasibility and Impact on Ventilation Compliance | January 2015 | December 2017 |
NCT03381937 | Unknown status | N/A | Impact of the Pre-phonatory Inspiratory Volume on the Speech Quality of Neuromuscular Patients Dependent on Non-invasive Ventilation | February 6, 2018 | January 2020 |
NCT04581577 | Unknown status | Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders | September 11, 2020 | April 30, 2021 | |
NCT04100993 | Unknown status | Multisystem and Autonomic Complications of NMD on Long-term NIV | October 25, 2019 | October 11, 2021 | |
NCT03964961 | Unknown status | N/A | Effect of Functional Massage in Neuromuscular Response. | February 5, 2019 | June 5, 2019 |
NCT03941067 | Unknown status | N/A | Effects of Pre-event Massage Over the Neuromuscular Response | May 2, 2019 | June 7, 2019 |
NCT04897113 | Unknown status | N/A | Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old | May 12, 2021 | December 30, 2022 |
NCT02789059 | Unknown status | N/A | Muscle Oxygenation in Effort in Neuromuscular Diseases | July 2, 2015 | July 2017 |
NCT04986059 | Unknown status | N/A | Effects of Pre-event Massage on Muscle Activity | October 2021 | April 2022 |
NCT03507530 | Unknown status | Effects of Fear of Falling on Physical Performance and Quality of Life in Children With Duchenne Muscular Dystrophy | April 2018 | January 2019 | |
NCT03504514 | Unknown status | N/A | Evaluation of the Effect of a Speech Detection Tool on the Improvement of Phonation in Neuromuscular Patients Dependent on Mechanical Ventilation | November 6, 2019 | September 2020 |
NCT02997514 | Unknown status | N/A | Solution Focused Coaching Strategy Within a Paediatric Multidisciplinary Neuromuscular Clinic | January 2017 | November 2019 |
NCT02097368 | Unknown status | Bulbar Function in Neuromuscular Patients | April 2014 | December 2020 | |
NCT00331656 | Unknown status | Phase 4 | Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. | June 2008 | December 2009 |
NCT04098094 | Unknown status | Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases | September 19, 2019 | October 30, 2022 | |
NCT05227274 | Unknown status | Reliability Study of a Motor Function Measure Digitalized Playful Completion Modules | April 2022 | June 2024 | |
NCT03272802 | Unknown status | Phase 2/Phase 3 | Treatment Effect of Edaravone in Patients With Amyotrophic Lateral Sclerosis (ALS) | March 16, 2017 | September 16, 2019 |
NCT05597592 | Withdrawn | N/A | Experimentation of a Personalized Physical Self-education Program at Home: Feasibility Study (PROSOL TELEKINECT) | February 2023 | October 2023 |
NCT04758052 | Withdrawn | N/A | Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placement | March 31, 2021 | August 2022 |
NCT04173975 | Withdrawn | N/A | Validation of the Efficacy and Usability of the BELK Orthosis Knee Module in a Neurological Setting (BELK@CCP) | January 1, 2021 | August 31, 2021 |
NCT03775135 | Withdrawn | Identity Development in Youth With Neuromuscular Diseases | January 1, 2019 | February 1, 2020 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D009468