Neuromuscular Diseases

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Information
Disease name
Neuromuscular Diseases
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05479981 Active, not recruiting Phase 2 Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients August 4, 2022 June 2025
NCT05337553 Active, not recruiting Phase 3 A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy July 6, 2022 January 2025
NCT05070624 Active, not recruiting N/A The Peer Support Study September 15, 2022 December 30, 2024
NCT05206617 Active, not recruiting 3 Year Follow up on ANO5 Patients January 1, 2018 November 1, 2025
NCT03355105 Active, not recruiting N/A Comparison of Two Methods of Adjusting the Mechanical In-Exsuflation in Neuromuscular Adult Patients March 7, 2019 December 24, 2024
NCT03478566 Active, not recruiting N/A Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease October 1, 2018 September 1, 2023
NCT03548779 Active, not recruiting N/A North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 September 28, 2018 September 8, 2024
NCT05156320 Active, not recruiting Phase 3 Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam February 24, 2022 December 2024
NCT05626855 Active, not recruiting Phase 3 Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab-ONYX April 17, 2023 January 1, 2027
NCT01826487 Completed Phase 3 Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) March 26, 2013 August 20, 2015
NCT00002044 Completed N/A A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases
NCT05771727 Completed Impact of Covid-19 Pandemic on Children With Neuromuscular Disease and Their Parents in Turkey: Parent Perspective July 1, 2021 October 1, 2021
NCT05730842 Completed Phase 1 Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers January 12, 2023 April 6, 2023
NCT02208687 Completed N/A Effectiveness and Cost-effectiveness of the Energetic Program August 2014 May 2017
NCT02242162 Completed Establishment of a Non-invasive and Indirect Measure of Volitional Pimax May 2009 January 2016
NCT02342132 Completed N/A Methods to Improve Expiratory Cough Flow and Lung Volume in Children With NMDs August 2014 February 2015
NCT02436096 Completed Phase 3 A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia April 2015 September 2016
NCT02500030 Completed N/A Air Stacking vs Glossopharyngeal Breathing in Neuromuscular Diseases June 2013 June 2014
NCT02743702 Completed N/A Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease June 2012 December 2014
NCT02753959 Completed N/A Changes in Regional Lung Ventilation Following Mechanical Insufflation-Exsufflation August 1, 2016 September 30, 2019
NCT05460156 Completed N/A The Bridges Self-management Programme for People With Neuromuscular Diseases February 14, 2022 November 27, 2023
NCT02845362 Completed N/A Validation of the French Version of the Sydney Swallow Questionnaire in Patients With Neuromuscular Diseases August 2016 October 2018
NCT05353738 Completed Efficacy of Vaccination Against COVID-19 in Patients Presenting a Neuromuscular Disease With Severe Amyotrophy September 1, 2021 September 1, 2022
NCT05311904 Completed Efficacy and Safety of Vaccination Against COVID-19 in Neuromuscular Patients March 11, 2021 February 3, 2023
NCT03085537 Completed Effectiveness Monitoring of Home Non-invasive Mechanical Ventilation by Digital Diagnosis Platform October 1, 2016 October 30, 2021
NCT03127514 Completed Phase 2 AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) June 22, 2017 November 24, 2019
NCT03179631 Completed Phase 3 Long-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy July 6, 2017 July 25, 2023
NCT03203577 Completed N/A Initiation of Home Mechanical Ventilation at Home in Patients With Chronic Hypercapnic Respiratory Failure July 2015 May 2018
NCT03218215 Completed Monitoring Mechanical Assisted Cough May 1, 2015 May 31, 2017
NCT05239520 Completed Understanding Control and Mechanisms of Shoulder Instability in FSHD March 25, 2022 October 21, 2022
NCT03289715 Completed N/A Evaluation of an On-Demand Humidifier on Neuromuscular Patients Requiring Mechanical Ventilation January 12, 2018 July 31, 2018
NCT03312361 Completed N/A Assessing Air Travel Safety in Neuromuscular Dystrophy: Standard Versus Prolonged High Altitude Simulation Tests April 1, 2016 April 1, 2018
NCT03394859 Completed Electronic Medical Records and Genomics (eMERGE) Phase III September 1, 2015 April 1, 2020
NCT03406780 Completed Phase 2 A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy March 4, 2018 March 10, 2020
NCT03440034 Completed Phase 1 Study of Pioglitazone in Sporadic Inclusion Body Myositis May 22, 2018 December 31, 2020
NCT03445832 Completed Pulmonary Function and Neuromuscular Disease January 8, 2018 February 10, 2018
NCT03458507 Completed N/A Impact of the Type of Interface in Neuromuscular Patients Treated With Nocturnal Noninvasive Ventilation May 28, 2018 June 26, 2019
NCT03465358 Completed Validation of Completion of Items 18, 19 and 22 of the Motor Function Measure (MFM) on a Digital Tablet March 14, 2018 November 28, 2018
NCT03506906 Completed N/A The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation November 11, 2018 September 21, 2020
NCT05070910 Completed N/A NDT Effectiveness Study October 25, 2021 March 31, 2022
NCT04473612 Completed Physical Status and Upper Airway Function in Neuromuscular Patients July 20, 2020 September 1, 2020
NCT04435093 Completed Digitalization Playful Module of Motor Function Measure Assessment for Children With Neuromuscular Disorders, MFM-Play Pilot Study. September 21, 2020 March 4, 2021
NCT00720161 Completed N/A Metformin in Children With Motor Deficit November 2006 July 2011
NCT06031701 Completed N/A Neuro-psychosocial Teleassistance for Neuromuscular Diseases November 2, 2021 June 30, 2023
NCT00942227 Completed Phase 3 The Value of Traction in Treatment of Lumbar Radiculopathy July 2009 December 2012
NCT00979108 Completed Phase 3 The Value of Traction in the Treatment of Cervical Radiculopathy July 2009 January 2013
NCT01022931 Completed Epidemiology and Clinical Presentation of H1N1 Infection in Children in Geneva October 2009 July 2012
NCT01313325 Completed N/A Hippotherapy to Improve the Balance of Children With Movement Disorders September 2006 December 2007
NCT01495390 Completed A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers November 2011 December 31, 2016
NCT04652401 Completed Quality of Life in Ventilator-dependant Neuromuscular Patients December 2, 2020 December 7, 2021
NCT04106154 Completed N/A Impacting Children's Physical and Mental Health Through Kinesiology Support in Clinical Care November 4, 2019 December 31, 2022
NCT03623698 Completed Nebulised Hypertonic Saline in Children and Young People With Neuromuscular Disease and Cerebral Palsy June 15, 2018 September 26, 2019
NCT03627962 Completed N/A Oculomotor Training and Chinese Characters Recognition in Children With Neuromuscular Disease November 1, 2016 August 8, 2018
NCT03645031 Completed N/A Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease October 1, 2018 June 2, 2023
NCT05021744 Completed Do Handgrip Strength and Dexterity Predict of Respiratory Function ? December 13, 2014 January 1, 2016
NCT04935905 Completed Accuracy of Peak Cough Flow Measurements Using a Mechanical Insufflator-exsufflator December 4, 2020 September 1, 2021
NCT03824223 Completed N/A 'Fitness To Fly' Tests In Children With Type II Respiratory Failure February 1, 2019 August 31, 2021
NCT03831568 Completed Mechanical Cough Augmentation in Children With NMD January 1, 2018 January 31, 2019
NCT03863496 Completed N/A Efficacy of Surgical Treatment by Different Pedicle Screw Systems in Pediatric Neuromuscular Spinal Deformity January 31, 2018 February 14, 2021
NCT03867721 Completed N/A Patient Preference for Mouthpiece Ventilation January 1, 2015 December 30, 2018
NCT03921528 Completed Phase 2 An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy April 22, 2019 February 28, 2024
NCT04837157 Completed N/A Evaluation of the Exoskeleton ATLAS 2030 as Robot-assisted Physical Therapy to Children With Neuromuscular Diseases October 15, 2020 January 31, 2021
NCT04813601 Completed N/A Rehabilitative Effect of the Use of a Gait Exoskeleton in Patients With Neuromuscular Disease or Cerebral Palsy March 9, 2020 September 24, 2023
NCT04729920 Completed Home Use of Mechanical Insufflation/Exsufflation Devices in Neuromuscular Diseases September 15, 2019 May 1, 2020
NCT06428864 Completed Effect of the Use of a 3D Scanner Application on a Smartphone to Mold Garchois Orthotic Device in Neuromuscular Diseases Patients With Scoliosis September 1, 2023 November 1, 2023
NCT05099107 Enrolling by invitation N/A Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment October 25, 2021 December 31, 2025
NCT05539456 Enrolling by invitation Reliability and Validity of the Turkish Version of the PedsQL 3.0 Neuromuscular Module for 2-to 4- Year-old September 1, 2022 November 1, 2022
NCT05831514 Not yet recruiting N/A Developing a Mobile Application for the Care of Children With Gastrostomy and The Effect of the Application on Gastrostomy July 28, 2023 August 28, 2024
NCT04089696 Not yet recruiting N/A Validation of the "ExSpiron©" in Patients With ALS September 2025 September 2025
NCT04866459 Not yet recruiting MYO-SHARE: MYO-MRI in Neuromuscular Diseases May 30, 2021 May 30, 2031
NCT05785546 Not yet recruiting Elaboration of a Pronostic Score of Changes on Wheelchair's Seating System September 2024 March 2028
NCT06119087 Not yet recruiting N/A Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study June 1, 2024 December 31, 2025
NCT06134401 Not yet recruiting N/A Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability April 2024 December 2026
NCT06151600 Not yet recruiting A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J March 1, 2024 March 1, 2028
NCT06367686 Not yet recruiting Detecting Systemic Carbon Dioxide Levels With a Novel Biosensor May 2024 December 2024
NCT06379932 Not yet recruiting Pain and Muscle Biopsy July 1, 2024 December 1, 2024
NCT06438965 Not yet recruiting MSOT as Non-invasive Biomarker for Diagnosis and Monitoring of Neuromuscular Diseases July 2024 July 2028
NCT06084026 Recruiting Measuring Physical Activity With ActivPal November 1, 2020 August 2024
NCT06259643 Recruiting N/A Effects of Power Wheelchair Soccer for Individuals Presenting With Physical Impairments November 1, 2023 June 15, 2024
NCT03797183 Recruiting Genesis Electrical Impedance Tomography (EIT): A Preliminary Study May 3, 2019 November 30, 2024
NCT05006859 Recruiting Wheelchair Positioning and Neuromuscular Diseases May 17, 2021 December 2024
NCT05048862 Recruiting The Neuroimage Study of the Neuromuscular Disorders. August 1, 2021 August 1, 2031
NCT05051254 Recruiting N/A Respiratory Muscles and Work of Breathing in Children January 19, 2022 January 2028
NCT05126758 Recruiting Phase 3 A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy June 22, 2022 December 2026
NCT05189600 Recruiting Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms? January 1, 2022 January 1, 2025
NCT05318638 Recruiting N/A Soft-robotic Glove Support of High-demand Tasks October 17, 2022 December 2024
NCT05328492 Recruiting N/A Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis March 15, 2022 March 15, 2024
NCT05346263 Recruiting N/A Efficacy of Intermittent Abdominal Pressure Ventilation in Neuromuscular Patients March 1, 2022 March 1, 2025
NCT02851043 Recruiting N/A Non-Invasive Respiratory Monitor August 2014 September 2024
NCT05366010 Recruiting N/A Oscillation and Lung Expansion (OLE) for Treatment of Neuromuscular Disease Patients November 4, 2021 April 2024
NCT05434572 Recruiting MDTRP Neuromuscular Research Biobank March 17, 2021 February 2030
NCT02253290 Recruiting Neuropsychological and Psychosocial Follow up of Children and Adolescents With Neuromuscular Disease December 2014 April 2025
NCT05544994 Recruiting N/A The Effect of Aerobic Exercise Training in Patients With Type III Spinal Muscular Atrophy July 28, 2022 September 30, 2024
NCT05723289 Recruiting Evaluation of the Feasibility of Remote Monitoring of Mechanical In-exsufflation Devices in Paralytic and Neuromuscular Patients Treated at Home. June 2023 December 2023
NCT06339580 Recruiting Phase 2 Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease April 9, 2024 April 2026
NCT05785637 Recruiting Polygraphy at Home for Neuromuscular Patients Under Non-invasive Mechanical Ventilation March 8, 2024 March 2026
NCT05798325 Recruiting N/A Feasibility, Validation and Application of Digital Tools for the Follow-up of Neuromuscular Patient Mobility in Daily Living June 29, 2023 June 30, 2024
NCT06074822 Recruiting Research Biobank From Neuromuscular Biopsy Residues (in the Context of Care) June 26, 2023 June 25, 2053
NCT06439823 Recruiting N/A Controlled Study of Upper and Lower Limb Movements in Patients With Neurological Pathologies August 24, 2022 August 2028
NCT06381284 Recruiting Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment March 28, 2024 May 27, 2025
NCT06190431 Recruiting N/A Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects? November 20, 2023 December 31, 2024
NCT06207591 Recruiting N/A Investigation on the Cortical Communication System December 15, 2023 October 2027
NCT06226376 Recruiting N/A Mollii Suit and Fibromyalgia (EXOFIB 2) January 8, 2024 July 1, 2025
NCT04236726 Recruiting Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure December 19, 2019 May 31, 2025
NCT04283175 Recruiting Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients April 1, 2021 April 1, 2024
NCT04380649 Recruiting N/A Development and Test of a Headset for BCI Until Obtaining an Efficient and Comfortable System That Can be Used in Daily Practice by ALS People February 13, 2023 February 2025
NCT04163198 Recruiting N/A Optimisation of Mechanical Insufflation:Exsufflation December 19, 2019 May 31, 2025
NCT04541602 Recruiting Detection of Neuromuscular Complications in Critically Ill Patients September 1, 2020 March 31, 2023
NCT03945968 Recruiting The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. July 1, 2019 February 28, 2025
NCT03353064 Terminated N/A Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure October 18, 2017 October 26, 2018
NCT03694431 Terminated N/A Comparative Trial of Home-Based Palliative Care January 7, 2019 January 24, 2020
NCT02078050 Terminated N/A Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures November 2013 May 2015
NCT04226144 Terminated N/A Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients January 6, 2020 December 1, 2022
NCT02829814 Terminated Phase 3 Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With Fibromyalgia July 2016 September 2016
NCT00839033 Terminated Phase 3 Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders June 2009 December 2011
NCT02951572 Terminated N/A Non-invasive Ventilation and Physical Activity February 2013 June 2017
NCT02090959 Terminated Phase 3 An Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy March 20, 2014 June 12, 2018
NCT05122273 Unknown status Assessment of the Effectiveness of Muscle Activating Training With the Use of EMG Biofeedback in Patients With Neuromuscular Diseases November 20, 2021 February 28, 2022
NCT02103790 Unknown status N/A Installation of Non-invasive Ventilation at Home Using Telemedicine : a Pilot Study on Feasibility and Impact on Ventilation Compliance January 2015 December 2017
NCT03381937 Unknown status N/A Impact of the Pre-phonatory Inspiratory Volume on the Speech Quality of Neuromuscular Patients Dependent on Non-invasive Ventilation February 6, 2018 January 2020
NCT04581577 Unknown status Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders September 11, 2020 April 30, 2021
NCT04100993 Unknown status Multisystem and Autonomic Complications of NMD on Long-term NIV October 25, 2019 October 11, 2021
NCT03964961 Unknown status N/A Effect of Functional Massage in Neuromuscular Response. February 5, 2019 June 5, 2019
NCT03941067 Unknown status N/A Effects of Pre-event Massage Over the Neuromuscular Response May 2, 2019 June 7, 2019
NCT04897113 Unknown status N/A Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old May 12, 2021 December 30, 2022
NCT02789059 Unknown status N/A Muscle Oxygenation in Effort in Neuromuscular Diseases July 2, 2015 July 2017
NCT04986059 Unknown status N/A Effects of Pre-event Massage on Muscle Activity October 2021 April 2022
NCT03507530 Unknown status Effects of Fear of Falling on Physical Performance and Quality of Life in Children With Duchenne Muscular Dystrophy April 2018 January 2019
NCT03504514 Unknown status N/A Evaluation of the Effect of a Speech Detection Tool on the Improvement of Phonation in Neuromuscular Patients Dependent on Mechanical Ventilation November 6, 2019 September 2020
NCT02997514 Unknown status N/A Solution Focused Coaching Strategy Within a Paediatric Multidisciplinary Neuromuscular Clinic January 2017 November 2019
NCT02097368 Unknown status Bulbar Function in Neuromuscular Patients April 2014 December 2020
NCT00331656 Unknown status Phase 4 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. June 2008 December 2009
NCT04098094 Unknown status Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases September 19, 2019 October 30, 2022
NCT05227274 Unknown status Reliability Study of a Motor Function Measure Digitalized Playful Completion Modules April 2022 June 2024
NCT03272802 Unknown status Phase 2/Phase 3 Treatment Effect of Edaravone in Patients With Amyotrophic Lateral Sclerosis (ALS) March 16, 2017 September 16, 2019
NCT05597592 Withdrawn N/A Experimentation of a Personalized Physical Self-education Program at Home: Feasibility Study (PROSOL TELEKINECT) February 2023 October 2023
NCT04758052 Withdrawn N/A Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placement March 31, 2021 August 2022
NCT04173975 Withdrawn N/A Validation of the Efficacy and Usability of the BELK Orthosis Knee Module in a Neurological Setting (BELK@CCP) January 1, 2021 August 31, 2021
NCT03775135 Withdrawn Identity Development in Youth With Neuromuscular Diseases January 1, 2019 February 1, 2020
MeSH unique ID (MeSH (Medical Subject Headings))
D009468