pterygium
Information
- Disease name
- pterygium
- Disease ID
- DOID:0002116
- Description
- "A corneal disease that is characterized by a triangular tissue growth located_in cornea of the eye that is the result of collagen degeneration and fibrovascular proliferation." [url:https\://en.wikipedia.org/wiki/Pterygium_(conjunctiva)]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06200727 | Active, not recruiting | N/A | Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases | January 1, 2023 | December 31, 2025 |
| NCT05794204 | Active, not recruiting | Phase 2 | RMP-A03 Ocular Suspension in Patients With Pterygium | June 9, 2023 | July 2024 |
| NCT00320957 | Completed | Phase 3 | Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Zhong-Shan Hospital | January 2006 | December 2006 |
| NCT00321035 | Completed | Phase 3 | Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in Beijing Remin Hospital | December 2005 | |
| NCT00344201 | Completed | Phase 1 | Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of External Eye Surgery | November 2004 | January 2008 |
| NCT00346450 | Completed | Phase 3 | Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation | October 2001 | December 2003 |
| NCT00383825 | Completed | N/A | ICG Angiography in Amniotic Membrane Graft and Conjunctival Autograft After Pterygium Excision | January 2003 | December 2004 |
| NCT00391573 | Completed | N/A | Polyglactin Sutures Versus Nylon Sutures for Suturing of Conjunctival Autograft in Pterygium Surgery: a Randomised Controlled Trial | March 2005 | June 2005 |
| NCT00457223 | Completed | Phase 2/Phase 3 | To Compare Fibrin Glue and Suture in Primary Pterygium Excision With Amniotic Membrane Transplantation | April 2007 | August 2007 |
| NCT03049852 | Completed | Phase 2 | Safety and Efficacy of CBT-001 Ophthalmic Solution in Patients With Pterygium | April 15, 2017 | April 30, 2018 |
| NCT00320762 | Completed | Phase 3 | Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Beijing Hospital | January 2006 | |
| NCT02866968 | Completed | N/A | Clinical Outcomes of Femtosecond Laser-assisted Pterygium Surgery (FLAPS) | July 6, 2016 | June 2017 |
| NCT05627947 | Completed | Phase 1 | Comparison Between Topical Mitomycin C and Cyclosporine | January 1, 2021 | June 30, 2022 |
| NCT00592176 | Completed | Phase 2 | The Effect of Bevacizumab (Avastin) on Pterygium | August 2007 | March 2010 |
| NCT05314673 | Completed | Phase 4 | Preoperative Bevacizumab Injection in Primary Pterygium in Tunisian Patients | January 1, 2019 | January 1, 2021 |
| NCT00713180 | Completed | N/A | Determinants of Pterygium Occurrence and Recurrence in a Rural African Population | August 2008 | February 2012 |
| NCT00768963 | Completed | Phase 1 | Ranibizumab for the Inhibition of Neovascularization in Pterygia | October 2008 | January 2012 |
| NCT00949728 | Completed | N/A | Conjunctival Autologous Transplantation Using Fibrin Glue in Primary Pterygia | October 2006 | July 2009 |
| NCT01003613 | Completed | Phase 3 | Evaluation of Tranilast to Treat Pterygium Before Excision | February 2009 | March 2012 |
| NCT01024257 | Completed | Phase 3 | Pterygium Treatment Using Single Beta-therapy as Adjuvant Treatment Compared to Conjunctival Autograft | ||
| NCT05164900 | Completed | N/A | Manifestations of Ocular Irritation Following Pterygium Excision With Sutures Fixed Conjunctival Autograft | July 1, 2020 | October 1, 2021 |
| NCT01083927 | Completed | N/A | Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision | July 2007 | July 2009 |
| NCT01109056 | Completed | Phase 2 | Safety and Efficacy of Cyclosporine Ophthalmic Emulsion in Patients With Primary Pterygium | June 2010 | June 2011 |
| NCT01115517 | Completed | Phase 2 | Safety Study of Avastin Used as Adjunctive Therapy in Pterygium Surgery | October 2010 | July 2015 |
| NCT01169909 | Completed | Phase 1 | Efficacy and Safety of Sub-tenon Ranibizumab for Recurrent Pterygia | August 2010 | July 2014 |
| NCT04403516 | Completed | Phase 4 | Dextenza in Pterygium Surgery | October 1, 2020 | August 5, 2021 |
| NCT01250353 | Completed | Phase 2 | The Use of Natural Latex Biomembrane in Ocular Surface Reconstruction | June 2006 | July 2009 |
| NCT04151017 | Completed | N/A | Efficacy of Autologous Fibrin Glue in Pterygium | June 12, 2019 | December 1, 2020 |
| NCT01311960 | Completed | Phase 3 | Topical Bevacizumab for Preventing Recurrent Pterygium | December 2010 | April 2013 |
| NCT04117386 | Completed | Prevalence of HPV-associated Eye Infection and Cytokine Levels in Tears From Patients Diagnosed With Pterygium | January 1, 2020 | June 15, 2020 | |
| NCT04022811 | Completed | Phase 4 | Effect of Bromfenac on Pain Related to Pterygium Surgery | October 2016 | October 2017 |
| NCT01686529 | Completed | Phase 1 | Bevacizumab for Primary Pterygium Treatment | March 2010 | February 2012 |
| NCT01736449 | Completed | Phase 4 | Role of Sub-Conjunctival Bevacizumab in Post Pterygium Excision Management | April 2011 | April 2012 |
| NCT02002338 | Completed | Different Surgical Techniques for Pterygium Surgery | February 2013 | October 2013 | |
| NCT02009072 | Completed | N/A | Comparison Between Sutureless and Glue Free Versus Sutured Limbal Conjunctival Autograft in Primary Pterygium Surgery | April 2010 | November 2012 |
| NCT03533244 | Completed | Phase 2 | A Study of the Response to AG-86893 in Patients With Pterygium Hyperemia | October 11, 2018 | October 25, 2019 |
| NCT03521791 | Completed | Phase 4 | Efficacy and Safety of PRO-155 on Inflammation of the Conjunctival Surface in Subjects With Grade I-III Pterygium vs Placebo. | December 13, 2017 | October 31, 2018 |
| NCT03485001 | Completed | N/A | Treatment of Primary Type I Pterygia With Argon Laser | March 2014 | October 2016 |
| NCT02138019 | Completed | N/A | The Application of Fibrin Glue (Tissucol Duo Quick) in External Eye Surgeries | December 2009 | December 2013 |
| NCT03377348 | Completed | N/A | Subconjunctival Injection of Triamcinolone Acetonide and Limited Peritomy During Pterygium Excision | December 1, 2017 | December 1, 2019 |
| NCT02151305 | Completed | N/A | Different Hemostasis According to the Anesthetic Agents | August 2010 | April 2012 |
| NCT03204084 | Completed | Assessment of Low-temperature Plasma Surgery System in Pterygium With Fibrin Glue and Conjunctival Autografts | August 2016 | April 2017 | |
| NCT02342392 | Completed | Phase 2/Phase 3 | Intralesional Ranibizumab on Pterygium Vascularity, Size and Recurrence Rate: a Pilot Study | September 2012 | September 2014 |
| NCT06042296 | Not yet recruiting | Expression of CD44, PCNA and E-cadherin in Pterygium Tissue | October 2023 | January 2024 | |
| NCT06402643 | Recruiting | N/A | Comparison of Recurrence Between Mini-SLET and Limbal-Conjunctival Autograft Techniques in Primary Pterygium | June 22, 2024 | December 31, 2025 |
| NCT05456425 | Recruiting | Phase 3 | A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium | June 30, 2022 | December 31, 2026 |
| NCT05978687 | Recruiting | Phase 4 | The Use of Lidocaine Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision | September 1, 2023 | December 31, 2024 |
| NCT02116062 | Terminated | N/A | Robotic Surgery of the Ocular Surface | June 2014 | April 2018 |
| NCT01068496 | Terminated | Risk Factors and Biomarkers Associated With Recurrence After Excision of Primary Pterygium | March 2010 | December 2014 | |
| NCT03217500 | Unknown status | N/A | Corneal Epithelial Autograft for Pterygium | July 20, 2017 | December 30, 2019 |
| NCT03301974 | Unknown status | N/A | A Comparison Between Surgical Techniques for Securing Conjunctival Autografting in Primary Pterygium Surgery | February 24, 2019 | January 2020 |
| NCT03304366 | Unknown status | Corneal Changes With Pentacam Before and After Pterygium | November 2017 | January 2019 | |
| NCT03314389 | Unknown status | N/A | The Corneal and Conjunctiva Sensation Before and After Pterygium Surgeries | May 1, 2018 | October 1, 2019 |
| NCT02148016 | Unknown status | Phase 1/Phase 2 | Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell Transplantation | December 2012 | September 2014 |
| NCT02102776 | Unknown status | N/A | Intraoperative Mitomycin C, Amniotic Membrane Transplantation and Conjunctival Autograft for Primary Pterygium | December 2015 | December 2017 |
| NCT02015000 | Unknown status | N/A | Surgical Result of Pterygium Extended Removal Followed by Fibrin Glue Assisted Amniotic Membrane Transplantation | November 2013 | November 2014 |
| NCT01387971 | Unknown status | Using Impression Cytology to Observe the Cytological Changes of Ocular Surface Cells in Various Ocular Surface Disorders | September 2009 | August 2012 | |
| NCT01380678 | Unknown status | Phase 3 | Intralesional Bevacizumab Injection on Primary Pterygium | January 2009 | December 2012 |
| NCT01261455 | Unknown status | N/A | Prospective Randomized Pilot Study Comparing Inferior Versus Superior Conjunctival Autografts for Primary Pterygia | October 2010 | October 2012 |
| NCT01249235 | Unknown status | N/A | Bandage Contact Lens and Oral Analgesics Versus Patching and Oral Analgesics for Pain Following Pterygium Surgery | October 2010 | October 2011 |
| NCT04682054 | Unknown status | N/A | Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics | January 15, 2021 | December 31, 2021 |
| NCT04683159 | Unknown status | N/A | Brimonidine Tartrate for Pterygium Surgery | February 2021 | September 2021 |
| NCT05026307 | Unknown status | N/A | Corneal Topographic Changes After Pterygium Surgery | June 15, 2021 | February 2022 |
| NCT00704977 | Unknown status | N/A | Alcohol 20% for Separation of Pterygium and Comparison of Different Wound Closure Methods | June 2008 | July 2010 |
| NCT00326560 | Unknown status | Phase 3 | Comparison of Glue With Sutures for Pterygium Surgery | May 2006 | September 2007 |
| NCT00563667 | Unknown status | N/A | Effect of Pterygium Excision on Intraocular Lens Power Calculation for Subsequent Cataract Operation | December 2003 | December 2004 |
| NCT00563277 | Unknown status | N/A | Surgical Treatment of Concurrent Cataract and Primary Pterygium | October 2004 | December 2006 |
| NCT02911532 | Unknown status | N/A | Tissue Engineering Conjunctiva for the Treatment of Pterygium and Atretoblepharia | October 1, 2016 | April 1, 2018 |
| NCT02321150 | Unknown status | N/A | A Novel Technique for the Removal of Pterygiums | December 2013 | December 2014 |
| NCT02641132 | Unknown status | Phase 4 | Pterygium Head Body MMC1: Two Different Surgical Procedures and Their Effect on Endothelial Cell Count. | September 2015 | December 2016 |
| NCT00478790 | Unknown status | Phase 3 | Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital | February 2007 | October 2011 |
| NCT02782260 | Unknown status | Phase 2 | Assessment of the Efficacy of Ocular Dipyridamole in the Treatment of Dry Eye Symptomology in Subjects With Pterygium | July 2016 | January 2018 |
| NCT00155402 | Withdrawn | Phase 1 | The Application of Fibrin Glue in Ocular Surface Diseases | April 2005 | March 2008 |
- Disase is a (Disease Ontology)
- DOID:10124
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0033999
- Exact Synonym (Disease Ontology)
- surfer's eye
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001059
- ICD10 preferred id (Insert disease from ICD10)
- D0006040
- ICD10 class code (Insert disease from ICD10)
- H11.0
- MeSH unique ID (MeSH (Medical Subject Headings))
- D011625