Annotation Detail

Information
Associated Genes
MMP2
Associated Variants
MMP2 MUTATION
MMP2 MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
While MMP-2 and uPA have been demonstrated to be important mediators of EMMPRIN signaling, the role of Cathepsin B in EMMPRIN-mediated molecular cascades and tumorigenesis has not been established.
Pubmed
24705283
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00271441872080303
Drugs