Annotation Detail

Information
Associated Genes
MMP2
Associated Variants
MMP2 MUTATION
MMP2 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
The present study demonstrated that GRP78 plays important roles in invasion and metastasis of ESCC, indicating that GRP78 might be used as a potential prognostic and therapeutic marker in patients with ESCC by modulating the expression of MMP-2 and MMP-9.
Pubmed
25976624
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN,RGD
DisGENET score for the Gene Disease association
0.289453348739382
Drugs