chr11:69641156:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr11:69,455,924-69,469,242 
hg38 chr11:69,641,156-69,654,474

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.084 squamous cell carcinoma Cyclin D1 overexpression is associated with poor clinicopathological outcome and... BeFree,GAD,LHGDN 24675814 Detail
0.084 squamous cell carcinoma Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their ... BeFree,GAD,LHGDN 25645517 Detail
0.204 Carcinoma, Transitional Cell Given that the tumor-promoting inflammation has been previously established in s... BeFree,CTD_human,LHGDN,RGD 24448750 Detail
<0.001 carcinosarcoma NA BeFree Detail
0.120 Cecal Neoplasms NA CTD_human Detail
0.120 Neoplastic Cell Transformation NA CTD_human Detail
<0.001 cerebral palsy NA BeFree Detail
0.006 Malignant tumor of cervix NA BeFree Detail
0.005 Uterine Cervical Neoplasm NA BeFree,GAD Detail
<0.001 chondrosarcoma NA BeFree Detail
0.002 Chromosome Aberrations NA GAD Detail
0.003 Congenital chromosomal disease NA BeFree Detail
0.003 ulcerative colitis NA BeFree,GAD Detail
0.122 Colonic Neoplasms NA BeFree,CTD_human Detail
0.017 colorectal carcinoma The elevated expression of ATG4B was highly correlated with CCND1 expression, co... BeFree 24991826 Detail
0.017 colorectal carcinoma Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorecta... BeFree 25146682 Detail
0.017 colorectal carcinoma Treatment with ganetespib (50 nM) for 24 hours inhibited cyclin D1 and pRb at th... BeFree 25296971 Detail
0.017 colorectal carcinoma Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of t... BeFree 25479723 Detail
0.017 colorectal carcinoma The significant association of CCND1 genotypes with colorectal cancer in Taiwan. BeFree 25809706 Detail
0.017 colorectal carcinoma Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase ... BeFree 25818893 Detail
0.017 colorectal carcinoma The quantitative level of the β-catenin protein was significantly decreased in t... BeFree 26316447 Detail
0.150 Colorectal Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
<0.001 Coxsackievirus Infections NA BeFree Detail
<0.001 craniosynostosis In conclusion, the expression of Cav-1 was downregulated in CRS and the role of ... BeFree 24943192 Detail
0.002 Crohn Disease NA GAD Detail
0.123 adenoid cystic carcinoma NA BeFree,CTD_human,LHGDN Detail
<0.001 Phyllodes Tumor NA BeFree Detail
<0.001 Mental Depression Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to ... BeFree 25358426 Detail
<0.001 depressive disorder Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to ... BeFree 25358426 Detail
0.002 DNA Damage NA GAD Detail
<0.001 Down syndrome NA BeFree Detail
<0.001 Drug abuse NA BeFree Detail
<0.001 Dwarfism NA BeFree Detail
0.013 Endometrial Neoplasms NA GAD,LHGDN Detail
0.003 endometriosis NA BeFree,LHGDN Detail
<0.001 Epithelial hyperplasia NA BeFree Detail
0.146 Esophageal Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
<0.001 Fatigue NA BeFree Detail
<0.001 Fatty Liver NA BeFree Detail
0.002 Fetal Diseases NA GAD Detail
<0.001 breast fibrocystic disease NA BeFree Detail
0.001 fibrosarcoma NA BeFree Detail
0.003 Fibrosis NA LHGDN Detail
<0.001 ganglioneuroma NA BeFree Detail
0.003 gastritis NA BeFree,GAD Detail
0.003 gastroesophageal reflux disease NA BeFree,GAD Detail
<0.001 Giant Cell Tumors NA BeFree Detail
0.008 glioblastoma NA BeFree,LHGDN Detail
<0.001 goiter NA BeFree Detail
<0.001 nodular goiter NA BeFree Detail
0.003 Giant Cell Granuloma NA LHGDN Detail
<0.001 Hamartoma NA BeFree Detail
0.008 Head and Neck Neoplasms The mitotic index and immunoreactivity of NF-kB, phospho-IkB, and cyclin D1 in t... BeFree,GAD,LHGDN 25454347 Detail
0.003 Heart Neoplasm NA LHGDN Detail
<0.001 hemangioma NA BeFree Detail
0.120 Hemangiosarcoma NA CTD_human Detail
0.003 Hemophilia A NA BeFree,GAD Detail
<0.001 hepatitis B NA BeFree Detail
0.123 Von Hippel-Lindau syndrome NA BeFree,CTD_human,LHGDN Detail
<0.001 HIV Infections NA BeFree Detail
0.001 Hodgkin Disease NA BeFree Detail
<0.001 Huntington disease NA BeFree Detail
<0.001 hyperglycemia NA BeFree Detail
0.124 hyperparathyroidism NA BeFree,CTD_human,LHGDN Detail
0.125 Hyperplasia NA CTD_human,LHGDN Detail
<0.001 Immunologic Deficiency Syndromes NA BeFree Detail
0.006 Inflammatory Bowel Diseases NA BeFree,GAD,LHGDN Detail
<0.001 Intestinal Neoplasms NA BeFree Detail
0.120 Intestinal Polyps NA BeFree,CTD_human Detail
0.003 keratoacanthoma NA LHGDN Detail
0.003 keratosis NA LHGDN Detail
0.002 Kidney Failure, Chronic NA GAD Detail
0.121 Kidney Neoplasm NA BeFree,CTD_human Detail
0.002 Laryngeal Diseases NA GAD Detail
0.005 Laryngeal neoplasm NA BeFree,GAD,LHGDN Detail
0.008 Fibroid Tumor NA BeFree,GAD,LHGDN Detail
<0.001 leiomyosarcoma NA BeFree Detail
0.128 leukemia NA BeFree,CTD_human,GAD Detail
0.256 chronic lymphocytic leukemia NA BeFree,CTD_human,GAD,ORPHANET Detail
<0.001 Acute Erythroblastic Leukemia NA BeFree Detail
0.007 hairy cell leukemia NA BeFree,LHGDN Detail
<0.001 lymphoid leukemia NA BeFree Detail
0.003 Acute lymphocytic leukemia NA BeFree Detail
<0.001 Leukemia, Lymphocytic, Acute, L1 NA BeFree Detail
0.002 Leukemia, Myelocytic, Acute NA BeFree Detail
0.004 myeloid leukemia NA BeFree,LHGDN Detail
<0.001 Leukemia, Myeloid, Accelerated Phase NA BeFree Detail
0.004 Myeloid Leukemia, Chronic Activation of FOXO1 and 3a and a decreased expression of their target gene Cycli... BeFree,LHGDN 24806995 Detail
<0.001 Leukemia, Plasma Cell NA BeFree Detail
<0.001 prolymphocytic leukemia NA BeFree Detail
0.003 Leukemia, T-Cell NA LHGDN Detail
<0.001 Adult T-Cell Lymphoma/Leukemia NA BeFree Detail
<0.001 Leukoencephalopathy, Progressive Multifocal NA BeFree Detail
0.003 Leukoplakia, Oral NA BeFree,GAD Detail
<0.001 Lichen Sclerosus et Atrophicus NA BeFree Detail
<0.001 Hyperlipoproteinemia Type I NA BeFree Detail
<0.001 liposarcoma NA BeFree Detail
<0.001 liver cirrhosis NA BeFree Detail
0.006 Liver neoplasms Annexin A2 knockdown inhibits hepatoma cell growth and sensitizes hepatoma cells... BeFree,GAD 25385370 Detail
0.080 Liver Neoplasms, Experimental NA RGD Detail
0.003 Chronic Obstructive Airway Disease In addition, we determined the expression patterns of connective tissue growth f... BeFree,GAD 25708588 Detail
0.137 Lung Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
0.002 Lymphatic Metastasis NA GAD Detail
<0.001 Lymphocytosis NA BeFree Detail
0.031 lymphoma Two cyclin D1-positive lymphomas with morphologic features of DLBCL and IGH-CCND... BeFree,LHGDN 25596256 Detail
0.006 Lymphoma, Follicular We present here a unique case of follicular lymphoma (FL) with rearranged BCL2, ... BeFree,GAD 25953460 Detail
<0.001 Small Cell Lymphoma NA BeFree Detail
0.010 Lymphoma, Non-Hodgkin NA BeFree,GAD,LHGDN Detail
0.004 Lymphoproliferative Disorders NA BeFree Detail
<0.001 Waldenstrom Macroglobulinemia NA BeFree Detail
0.012 Malignant neoplasm of stomach In conclusion, this CagA- PI3K/AKT-Sp1-RBP2-Cyclin D1 pathway may serve as a nov... BeFree,GAD 25015565 Detail
0.012 Malignant neoplasm of stomach To examine the expression patterns of ER-α36 and Cyclin D1 in human gastric canc... BeFree,GAD 25231129 Detail
0.012 Malignant neoplasm of stomach Correlation of RKIP, STAT3 and cyclin D1 expression in pathogenesis of gastric c... BeFree,GAD 25337233 Detail
0.012 Malignant neoplasm of stomach Moreover, the expression of WISP3 was positively correlated with the expression ... BeFree,GAD 25400723 Detail
0.012 Malignant neoplasm of stomach Fz2 shRNA suppressed cell proliferation and motility of MKN45 and MKN74 cells, a... BeFree,GAD 25586465 Detail
0.120 Animal Mammary Neoplasms NA CTD_human Detail
0.200 Mammary Neoplasms, Experimental NA CTD_human,RGD Detail
0.001 medulloblastoma NA BeFree Detail
0.021 melanoma FISH analysis of human acral melanoma expanding in the epidermis revealed that u... BeFree,LHGDN 25065272 Detail
0.001 multiple endocrine neoplasia type 1 NA BeFree Detail
0.011 meningioma NA BeFree,GAD,LHGDN Detail
<0.001 Mesothelioma NA BeFree Detail
0.003 Mixed Salivary Gland Tumor NA BeFree,LHGDN Detail
<0.001 Monoclonal Gammopathy of Undetermined Significance NA BeFree Detail
<0.001 Monosomy NA BeFree Detail
0.018 Mouth Neoplasms An association between CCND1 overexpression in oral tumors and poor prognosis ha... BeFree,GAD,LHGDN 24809775 Detail
0.397 multiple myeloma We showed tetraspanins attenuated peIF4E and its targets [c‑Myc, cyclin D1 (cycD... BeFree,CTD_human,GWASCAT,LHGDN,ORPHANET 25422161 Detail
0.397 multiple myeloma Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apop... BeFree,CTD_human,GWASCAT,LHGDN,ORPHANET 25881299 Detail
<0.001 Mycoses NA BeFree Detail
<0.001 mycosis fungoides NA BeFree Detail
<0.001 myocardial infarction NA BeFree Detail
0.002 Nasopharyngeal Neoplasms NA GAD Detail
<0.001 Neck Neoplasms NA BeFree Detail
0.026 Neoplasm Metastasis Head and neck squamous cell carcinoma (HNSCC) progression and metastasis have pr... BeFree,GAD,LHGDN 23730900 Detail
0.026 Neoplasm Metastasis The pooled results provided compelling evidence that cyclin D1 overexpression wa... BeFree,GAD,LHGDN 24675814 Detail
0.026 Neoplasm Metastasis RKIP expression in gastric cancer was negatively correlated with the invasion, T... BeFree,GAD,LHGDN 25337233 Detail
0.026 Neoplasm Metastasis To elucidate the underlying molecular mechanisms produced by these EDC, alterati... BeFree,GAD,LHGDN 25849766 Detail
0.026 Neoplasm Metastasis Our results suggest that the CCND1 A870G polymorphism might not be a potential c... BeFree,GAD,LHGDN 25888980 Detail
0.002 Neoplasm Recurrence, Local NA GAD Detail
0.120 Neoplasms, Experimental NA CTD_human Detail
<0.001 multiple endocrine neoplasia NA BeFree Detail
<0.001 nephroblastoma Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and meta... BeFree 25751590 Detail
<0.001 nephrotic syndrome NA BeFree Detail
<0.001 neurilemmoma NA BeFree Detail
0.006 neuroblastoma Cyclin D1 immunohistochemistry was also performed on tissue microarrays of other... BeFree,LHGDN 25751590 Detail
0.003 acoustic neuroma NA BeFree,GAD Detail
<0.001 Nevus NA BeFree Detail
0.001 Melanocytic nevus NA BeFree Detail
0.001 obesity NA BeFree Detail
0.003 osteosarcoma β-catenin protein expression was, however, detected in the membrane and cytoplas... BeFree 24942472 Detail
0.003 osteosarcoma When HMGN2 expression was enhanced, the expression of cyclin D1 and PCNA was dow... BeFree 25530340 Detail
0.003 osteosarcoma The cyclin D1 expression was significantly decreased following the treatment wit... BeFree 26434118 Detail
0.006 ovarian carcinoma The down regulation of β-catenin and cyclin-D1 in the tumor tissues may refer to... BeFree 24444073 Detail
0.006 ovarian carcinoma The cyclin D1 expression was significantly decreased following the treatment wit... BeFree 26434118 Detail
<0.001 Ovarian Diseases NA BeFree Detail
0.004 Pancreatic Neoplasm NA BeFree,LHGDN Detail
0.120 papilloma NA BeFree,CTD_human Detail
<0.001 paraganglioma Discordant results were observed for VEGFR1, p27, and p21 overexpressed in parag... BeFree 24390213 Detail
<0.001 Parathyroid Diseases NA BeFree Detail
0.007 Parathyroid Neoplasms While bi-allelic inactivation of CDC73/HRPT2 seems unique to parathyroid maligna... BeFree,LHGDN 26163537 Detail
<0.001 Peyronie Disease We observed that Ad-HDAC2 shRNA decreased inflammatory cell infiltration, reduce... BeFree 24841412 Detail
<0.001 Peyronie Disease Overexpression of the SMAD7 gene decreased the expression of cyclin D1 (a positi... BeFree 25532569 Detail
0.003 Peptic Ulcer NA BeFree,GAD Detail
<0.001 pheochromocytoma NA BeFree Detail
<0.001 pituitary adenoma NA BeFree Detail
0.001 Pituitary Diseases NA BeFree Detail
0.006 Pituitary Neoplasms NA BeFree,GAD,LHGDN Detail
<0.001 plague NA BeFree Detail
<0.001 plasmacytoma NA BeFree Detail
0.008 Adenomatous Polyposis Coli NA BeFree,LHGDN Detail
<0.001 polyps NA BeFree Detail
0.130 Precancerous Conditions Further studies in premalignant bronchial cells showed that the antiproliferativ... BeFree,CTD_human,GAD 25896445 Detail
<0.001 prolactinoma NA BeFree Detail
0.217 Prostatic Neoplasms NA BeFree,CTD_human,GAD,LHGDN,RGD Detail
<0.001 psoriasis NA BeFree Detail
0.080 Reperfusion Injury NA RGD Detail
0.020 retinoblastoma Following further examination of cell cycle-related factors, MCM2 knockdown inhi... BeFree,LHGDN 25738322 Detail
<0.001 Retroviridae Infections NA BeFree Detail
0.120 Salivary Gland Neoplasms NA CTD_human Detail
<0.001 Kaposi sarcoma NA BeFree Detail
0.080 Seizures NA RGD Detail
<0.001 Sertoli cell tumor NA BeFree Detail
<0.001 Sezary syndrome NA BeFree Detail
0.001 Skin Neoplasms NA BeFree Detail
<0.001 Soft Tissue Neoplasms NA BeFree Detail
0.141 Stomach Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
<0.001 gastric ulcer RKIP, STAT3 and cyclin D1 proteins were detected by immunohistochemistry in tiss... BeFree 25337233 Detail
0.002 synovial sarcoma NA BeFree Detail
0.003 Thrombocythemia, Essential NA LHGDN Detail
<0.001 thymoma NA BeFree Detail
<0.001 Thymus Hyperplasia NA BeFree Detail
0.135 Thyroid Neoplasm NA BeFree,CTD_human,LHGDN Detail
0.002 Chromosomal translocation NA GAD Detail
<0.001 Trisomy NA BeFree Detail
<0.001 tuberous sclerosis NA BeFree Detail
0.120 Urologic Neoplasms NA CTD_human Detail
<0.001 Uterine Fibroids NA BeFree Detail
0.002 Uterine Neoplasms NA GAD Detail
0.004 Fibromatosis, Aggressive NA BeFree,LHGDN Detail
0.020 B-Cell Lymphomas Mantle cell lymphoma (MCL) is a unique subtype of B-cell non-Hodgkin's lymphoma ... BeFree,GAD,LHGDN 24166616 Detail
<0.001 High Grade Lymphoma (neoplasm) NA BeFree Detail
0.006 diffuse large B-cell lymphoma Cyclin D1-positive diffuse large B-cell lymphoma with IGH-CCND1 translocation an... BeFree,GAD 25596256 Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
<0.001 Precursor cell lymphoblastic lymphoma NA BeFree Detail
<0.001 Diffuse Mixed-Cell Lymphoma NA BeFree Detail
<0.001 T-Cell Lymphoma NA BeFree Detail
0.003 Lymphoma, T-Cell, Cutaneous NA BeFree,LHGDN Detail
<0.001 peripheral T-cell lymphoma NA BeFree Detail
<0.001 Peripheral Vascular Diseases NA BeFree Detail
<0.001 cerebral amyloid angiopathy NA BeFree Detail
<0.001 Alcohol abuse NA BeFree Detail
<0.001 benign neoplasm NA BeFree Detail
<0.001 Pancreatitis, Chronic NA BeFree Detail
<0.001 Squamous cell carcinoma of lung NA BeFree Detail
<0.001 Small cell carcinoma of lung NA BeFree Detail
<0.001 Oral Cavity Carcinoma NA BeFree Detail
0.120 Myocardial Ischemia NA CTD_human Detail
0.001 Cutaneous Melanoma NA BeFree Detail
<0.001 Adenocarcinoma of lung (disorder) Furthermore, suppressed CCND1 and elevated caspase3 and caspase7 expression leve... BeFree 24972691 Detail
<0.001 Adenocarcinoma of lung (disorder) Furthermore, HMC-1 exosomes contain and transfer KIT protein, but not the c-KIT ... BeFree 25311367 Detail
0.007 esophageal carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of tongue The increased expression of pS(21)GSK3α and pS(9)GSK3β not only correlated posit... BeFree 25645517 Detail
0.014 Malignant neoplasm of mouth We used the odds ratio (OR) and hazard ratio (HR) as the common measures of asso... BeFree,GAD 24675814 Detail
0.014 Malignant neoplasm of mouth The expression of total and phosphorylated GSK3α/β as well as cyclin D1 and p53 ... BeFree,GAD 25645517 Detail
<0.001 Malignant neoplasm of nasopharynx NA BeFree Detail
<0.001 uterine cancer NA BeFree Detail
<0.001 Malignant tumor of parathyroid gland NA BeFree Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 acute myocardial infarction NA BeFree Detail
<0.001 adrenoleukodystrophy NA BeFree Detail
<0.001 Cicatrix, Hypertrophic NA BeFree Detail
<0.001 Agenesis of corpus callosum NA BeFree Detail
0.008 Tumor Progression NA BeFree Detail
<0.001 follicular adenoma NA BeFree Detail
<0.001 Undifferentiated carcinoma NA BeFree Detail
<0.001 Dysplastic Nevus NA BeFree Detail
<0.001 Liposarcoma, Dedifferentiated NA BeFree Detail
<0.001 Germ cell tumor NA BeFree Detail
<0.001 Sarcoma, Epithelioid NA BeFree Detail
<0.001 thymic carcinoma NA BeFree Detail
<0.001 Lichen Planus, Oral NA BeFree Detail
<0.001 Ki-1+ Anaplastic Large Cell Lymphoma NA BeFree Detail
<0.001 adenomyoma NA BeFree Detail
0.003 hepatoblastoma NA BeFree,LHGDN Detail
<0.001 Mesoblastic Nephroma Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and meta... BeFree 25751590 Detail
0.001 endometrial stromal sarcoma Furthermore, YWHAE-NUTM2 ESSs are strongly cyclin D1 positive in contrast to con... BeFree 25244606 Detail
0.001 endometrial stromal sarcoma This translocation also occurs in high-grade endometrial sarcoma, in which it is... BeFree 25751590 Detail
<0.001 Giant Cell Tumor of Bone NA BeFree Detail
<0.001 embryonal carcinoma NA BeFree Detail
<0.001 Neuroectodermal Tumor, Primitive NA BeFree Detail
<0.001 Medullary carcinoma NA BeFree Detail
<0.001 mucoepidermoid carcinoma NA BeFree Detail
0.007 cholangiocarcinoma NA BeFree,LHGDN Detail
0.003 verrucous carcinoma NA LHGDN Detail
<0.001 pilomatrixoma NA BeFree Detail
0.003 Squamous Cell Neoplasms NA BeFree,LHGDN Detail
<0.001 hemangioblastoma NA BeFree Detail
<0.001 Nevus, Blue NA BeFree Detail
<0.001 Epithelioid and spindle cell nevus NA BeFree Detail
0.003 Rhabdoid Tumor Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and meta... BeFree,LHGDN 25751590 Detail
<0.001 Neuroendocrine Tumors NA BeFree Detail
<0.001 Nevi and Melanomas NA BeFree Detail
<0.001 uveal melanoma Collectively, our results indicate that let-7b overexpression can in turn downre... BeFree 25588203 Detail
0.005 Lip and oral cavity carcinoma We used the odds ratio (OR) and hazard ratio (HR) as the common measures of asso... BeFree 24675814 Detail
0.005 Lip and oral cavity carcinoma The expression of total and phosphorylated GSK3α/β as well as cyclin D1 and p53 ... BeFree 25645517 Detail
0.001 Hyperparathyroidism, Primary NA BeFree Detail
<0.001 Comedone NA BeFree Detail
<0.001 Chondromyxoid fibroma NA BeFree Detail
<0.001 Malignant neoplasm of female breast NA BeFree Detail
0.007 pancreatic carcinoma MiR-219-1-3p overexpression (transient and stable) in pancreatic cancer cell lin... BeFree 24608432 Detail
0.007 pancreatic carcinoma WNT5A, p-AKT and Cyclin D1 were highly expressed in pancreatic cancer tissues, a... BeFree 25308364 Detail
0.007 pancreatic carcinoma Cyclin D1 is a strong prognostic factor for survival in pancreatic cancer: analy... BeFree 25470788 Detail
<0.001 Carcinoma of extrahepatic bile duct NA BeFree Detail
<0.001 Carcinoma of male breast NA BeFree Detail
<0.001 Gastrointestinal Stromal Tumors NA BeFree Detail
0.003 Cancer of Nasopharynx NA BeFree,GAD Detail
<0.001 Anaplastic thyroid carcinoma NA BeFree Detail
<0.001 Medullary carcinoma of thyroid NA BeFree Detail
0.002 Papillary thyroid carcinoma A cyclin D1 (CCND1) gene polymorphism contributes to susceptibility to papillary... BeFree 25227811 Detail
0.068 breast carcinoma We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
<0.001 Dyslipidemias A multivariate analysis revealed that the NR3C1 Bcl1 G allele was a significant ... BeFree 25944971 Detail
0.106 Malignant neoplasm of breast We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.080 Erectile dysfunction NA RGD Detail
0.024 Malignant neoplasm of lung Recently, we demonstrated that PML interacted with nuclear EGFR (nEGFR) and supp... BeFree,GAD 25486572 Detail
0.024 Malignant neoplasm of lung These effects may result from the ability of miR-5100 to promote G1/S transition... BeFree,GAD 25754817 Detail
0.001 Neoplasm, Residual NA BeFree Detail
0.003 Mucosa-Associated Lymphoid Tissue Lymphoma NA BeFree Detail
<0.001 Malignant neoplasm of male breast NA BeFree Detail
<0.001 Proliferative vitreoretinopathy The purpose of this study was to identify interacting signaling pathways by whic... BeFree 26247679 Detail
<0.001 Carcinoma, Small Cell NA BeFree Detail
0.007 parathyroid adenoma NA BeFree Detail
<0.001 Isovaleryl-CoA dehydrogenase deficiency NA BeFree Detail
<0.001 Parathyroid hyperplasia NA BeFree Detail
<0.001 Erythroblastosis NA BeFree Detail
<0.001 Virchow's node (disorder) NA BeFree Detail
<0.001 Malignant neoplasm of colon stage IV NA BeFree Detail
<0.001 Carcinoma breast stage IV NA BeFree Detail
<0.001 Non-small cell lung cancer stage III NA BeFree Detail
<0.001 Disseminated neuroblastoma NA BeFree Detail
<0.001 gastric adenocarcinoma NA BeFree Detail
0.006 Cancer of Head and Neck Cyclin D1-induced proliferation is independent of beta-catenin in head and neck ... BeFree,GAD 23730900 Detail
0.006 Cancer of Head and Neck Association of cyclin D1 variants with head and neck cancer susceptibility: evid... BeFree,GAD 25081680 Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
0.001 Invasive lobular breast carcinoma NA BeFree Detail
0.128 Squamous cell carcinoma of esophagus Cyclin D1 level correlated with Pin1 expression in clinical ESCC specimens. BeFree,CTD_human 25160749 Detail
0.002 Adenocarcinoma Of Esophagus NA BeFree Detail
<0.001 gallbladder adenocarcinoma The expressions of p21, p27, bcl-2, bcl-6 and cyclin D1 were not significant pro... BeFree 24178677 Detail
0.001 cervical squamous cell carcinoma NA BeFree Detail
<0.001 Transitional cell carcinoma of bladder NA BeFree Detail
<0.001 bladder squamous cell carcinoma Given that the tumor-promoting inflammation has been previously established in s... BeFree 24448750 Detail
<0.001 Conventional (Clear Cell) Renal Cell Carcinoma NA BeFree Detail
<0.001 Adenoid cystic carcinoma of salivary gland NA BeFree Detail
0.003 Solid tumour NA BeFree Detail
<0.001 stage, Kaposi's sarcoma NA BeFree Detail
<0.001 stage, non-small cell lung cancer NA BeFree Detail
0.005 laryngeal squamous cell carcinoma NA BeFree,GAD Detail
<0.001 Squamous cell carcinoma of vulva NA BeFree Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
<0.001 Bone Marrow Neoplasms NA BeFree Detail
<0.001 Prostatic Intraepithelial Neoplasias NA BeFree Detail
0.011 cervix carcinoma NA BeFree,GAD Detail
<0.001 Senile Plaques NA BeFree Detail
<0.001 High-Grade Squamous Intraepithelial Lesions NA BeFree Detail
<0.001 inflammatory myofibroblastic tumor NA BeFree Detail
<0.001 Fibrolamellar hepatocellular carcinoma NA BeFree Detail
<0.001 Superficial spreading malignant melanoma of skin NA BeFree Detail
<0.001 Clear cell sarcoma of kidney Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kid... BeFree 25751590 Detail
<0.001 anaplastic astrocytoma NA BeFree Detail
0.001 Malignant lymphoma - lymphoplasmacytic NA BeFree Detail
0.343 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Mantle cell lymphoma (MCL) is a unique subtype of B-cell non-Hodgkin's lymphoma ... BeFree,CTD_human,LHGDN,ORPHANET 24166616 Detail
0.343 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Fluorescence in situ hybridization in MCL cells showed that t(11;14)(q13;q32) re... BeFree,CTD_human,LHGDN,ORPHANET 24237447 Detail
0.343 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Mantle cell lymphoma is molecularly characterized by the chromosomal translocati... BeFree,CTD_human,LHGDN,ORPHANET 24857076 Detail
0.343 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Our study demonstrates convincingly that IGH-CCND1 rearrangement leading to cycl... BeFree,CTD_human,LHGDN,ORPHANET 25596256 Detail
0.343 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Interestingly, depletion of JARID1B inhibits Cyclin D1, which is one of the gene... BeFree,CTD_human,LHGDN,ORPHANET 25755704 Detail
<0.001 Malignant lymphomatous polyposis NA BeFree Detail
<0.001 Endometrial Stromal Tumors NA BeFree Detail
<0.001 Adenocarcinoma of colon NA BeFree Detail
<0.001 Proliferative retinopathy Since cyclin D1 is a key regulator of cell cycle G1/S phase progression essentia... BeFree 26247679 Detail
<0.001 Jaw Keratocyst NA BeFree Detail
<0.001 Human papilloma virus infection NA BeFree Detail
<0.001 Cerebellar decompression injury NA BeFree Detail
0.003 Malignant neoplasm of liver NA BeFree,GAD Detail
<0.001 intrahepatic cholangiocarcinoma NA BeFree Detail
<0.001 malignant mesothelioma NA BeFree Detail
<0.001 Stage 0 Skin Melanoma NA BeFree Detail
<0.001 Breast Cancer, Familial NA BeFree Detail
<0.001 Vulval intraepithelial neoplasia NA BeFree Detail
<0.001 Oncocytoma, renal NA BeFree Detail
0.003 pituitary carcinoma NA BeFree,GAD Detail
<0.001 Malignant melanoma of ciliary body NA BeFree Detail
<0.001 Multiple malignancy Analyses of human colon cancer databases also demonstrated a link between miR26b... BeFree 24785257 Detail
<0.001 Malignant neoplasm of large intestine NA BeFree Detail
0.007 Malignant neoplasm of pancreas MiR-219-1-3p overexpression (transient and stable) in pancreatic cancer cell lin... BeFree 24608432 Detail
0.007 Malignant neoplasm of pancreas WNT5A, p-AKT and Cyclin D1 were highly expressed in pancreatic cancer tissues, a... BeFree 25308364 Detail
0.007 Malignant neoplasm of pancreas Cyclin D1 is a strong prognostic factor for survival in pancreatic cancer: analy... BeFree 25470788 Detail
<0.001 Cervical intraepithelial neoplasia grade 1 NA BeFree Detail
<0.001 Squamous cell carcinoma of tongue NA BeFree Detail
<0.001 Richter's syndrome NA BeFree Detail
0.002 Splenic Marginal Zone B-Cell Lymphoma NA BeFree Detail
<0.001 Pre B-cell acute lymphoblastic leukemia NA BeFree Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
0.017 Malignant neoplasm of prostate The expression of prostate cancer-associated genes, including cyclin D1, IL-6, C... BeFree,GAD 25243457 Detail
0.017 Malignant neoplasm of prostate Formononetin could exhibit inhibitory activity against human prostate cancer cel... BeFree,GAD 25301361 Detail
0.017 Malignant neoplasm of prostate Moreover, our data suggest that TRAF6-mediated Lys63-linked ubiquitination of th... BeFree,GAD 25622187 Detail
0.017 Malignant neoplasm of prostate Effect of the CCND1 A870G polymorphism on prostate cancer risk: a meta-analysis ... BeFree,GAD 25888980 Detail
0.002 Hematopoietic Neoplasms NA BeFree Detail
<0.001 Hematologic Neoplasms NA BeFree Detail
<0.001 Hemimegalencephaly NA BeFree Detail
0.001 Trisomy 12 NA BeFree Detail
<0.001 Trisomy 11 NA BeFree Detail
<0.001 Chromosome 8, trisomy NA BeFree Detail
<0.001 Malignant lymphoma of spleen NA BeFree Detail
<0.001 Low grade B-cell lymphoma NA BeFree Detail
<0.001 Plasma cell tumor, malignant NA BeFree Detail
<0.001 Leukemia, Prolymphocytic, B-Cell NA BeFree Detail
0.005 endometrial carcinoma NA BeFree,GAD Detail
<0.001 Secondary malignant neoplasm of liver NA BeFree Detail
<0.001 Metabolic syndrome X NA BeFree Detail
<0.001 mantle lymphoma NA BeFree Detail
0.027 Malignant neoplasm of esophagus NA BeFree,GAD Detail
0.002 Thyroid carcinoma Cyclin D1 and c-Myc are important regulators of cancer cell growth, and we obser... BeFree 25854169 Detail
<0.001 Ewings sarcoma Prognostic significance of miR-34a in Ewing sarcoma is associated with cyclin D1... BeFree 25015333 Detail
<0.001 Oropharyngeal disorders NA BeFree Detail
<0.001 Squamous cell carcinoma of skin NA BeFree Detail
0.001 Malignant glioma NA BeFree Detail
<0.001 Malignant lymphoma - lymphocytic, intermediate differentiation NA BeFree Detail
<0.001 tongue carcinoma CCND1 and DACT3 overexpression in non-habits associated tongue carcinomas were s... BeFree 24809775 Detail
<0.001 tongue carcinoma The increased expression of pS(21)GSK3α and pS(9)GSK3β not only correlated posit... BeFree 25645517 Detail
0.003 Osteosarcoma of bone β-catenin protein expression was, however, detected in the membrane and cytoplas... BeFree 24942472 Detail
0.003 Osteosarcoma of bone When HMGN2 expression was enhanced, the expression of cyclin D1 and PCNA was dow... BeFree 25530340 Detail
0.003 Osteosarcoma of bone The cyclin D1 expression was significantly decreased following the treatment wit... BeFree 26434118 Detail
0.002 Carcinoma of larynx NA BeFree Detail
0.046 Carcinogenesis Western blotting analysis demonstrated that tumorigenesis related protein cyclin... BeFree 25120782 Detail
0.046 Carcinogenesis Cyclin D1 (CCND1) and E-cadherin (CDH1) are two important genes of the β-catenin... BeFree 25146682 Detail
0.046 Carcinogenesis AP-1 transcriptional activity was analyzed with a luciferase reporter and biolum... BeFree 25260534 Detail
0.046 Carcinogenesis This study aimed to investigate the correlation of RKIP, STAT3 and cyclin D1 exp... BeFree 25337233 Detail
0.046 Carcinogenesis The biological mechanism of CCND1 in carcinogenesis has not been fully examined;... BeFree 25470788 Detail
0.046 Carcinogenesis Cyclin D1 (CCND1) regulating cell cycle transition may determine the susceptible... BeFree 25809706 Detail
0.046 Carcinogenesis Cyclin D1 (CCND1) is critical in the transition of the cell cycle from the G1 to... BeFree 25888980 Detail
0.046 Carcinogenesis Aberrant nuclear β-catenin expression, detected in all MSTs, appears to be the r... BeFree 26200099 Detail
0.046 Carcinogenesis This study was performed to screen cyclin D1 (CCND1) and cyclin dependent kinase... BeFree 26416047 Detail
0.002 Leukemogenesis Furthermore, we demonstrate that PRMT5 overexpression specifically cooperates wi... BeFree 25582697 Detail
<0.001 Lymphoid neoplasm NA BeFree Detail
<0.001 Tumor Initiation NA BeFree Detail
0.011 prostate carcinoma Cyclin D1 expression in prostate carcinoma. BeFree 24820071 Detail
0.011 prostate carcinoma The expression of prostate cancer-associated genes, including cyclin D1, IL-6, C... BeFree 25243457 Detail
0.011 prostate carcinoma Formononetin could exhibit inhibitory activity against human prostate cancer cel... BeFree 25301361 Detail
0.011 prostate carcinoma Moreover, our data suggest that TRAF6-mediated Lys63-linked ubiquitination of th... BeFree 25622187 Detail
0.011 prostate carcinoma Effect of the CCND1 A870G polymorphism on prostate cancer risk: a meta-analysis ... BeFree 25888980 Detail
<0.001 CARCINOMA OF VULVA NA BeFree Detail
0.005 Epithelial ovarian cancer miR-211 suppresses epithelial ovarian cancer proliferation and cell-cycle progre... BeFree,GAD 25889927 Detail
0.005 Epithelial ovarian cancer The cyclin D1 expression was significantly decreased following the treatment wit... BeFree,GAD 26434118 Detail
<0.001 invasive cancer NA BeFree Detail
0.068 breast carcinoma Here, we demonstrate that two different ERβ agonists, WAY-20070 and a novel A-CD... BeFree 24785256 Detail
0.068 breast carcinoma Cyclin D1/CDK4 activity is upregulated in up to 50% of breast cancers and CDK4-m... BeFree 25006666 Detail
0.068 breast carcinoma Transcriptional CCND1 expression as a predictor of poor response to neoadjuvant ... BeFree 25200445 Detail
0.068 breast carcinoma We found that TBLR1 expression was implicated in the upregulation of cyclin D1, ... BeFree 25341494 Detail
0.068 breast carcinoma Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA... BeFree 25363551 Detail
0.068 breast carcinoma Genetic association between cyclin D1 polymorphism and breast cancer susceptibil... BeFree 25399071 Detail
0.068 breast carcinoma Estrogen receptor-α drives adiponectin effects on cyclin D1 expression in breast... BeFree 25657113 Detail
0.068 breast carcinoma We initiated the following study to directly test the oncogenic potential of cat... BeFree 25940700 Detail
0.068 breast carcinoma Genetic polymorphisms in cell cycle regulatory genes CCND1 and CDK4 are associat... BeFree 26416047 Detail
0.012 Carcinoma of lung Recently, we demonstrated that PML interacted with nuclear EGFR (nEGFR) and supp... BeFree 25486572 Detail
0.012 Carcinoma of lung These effects may result from the ability of miR-5100 to promote G1/S transition... BeFree 25754817 Detail
0.010 Secondary malignant neoplasm of lymph node In addition, amplification of CCND1 shows a negative predictive value of 80 % in... BeFree 25663615 Detail
0.002 Parathyroid Gland Adenocarcinoma Copy number variation in CCND1 gene is implicated in the pathogenesis of sporadi... BeFree 24510244 Detail
<0.001 extranodal lymphoma NA BeFree Detail
0.010 colon carcinoma Analyses of human colon cancer databases also demonstrated a link between miR26b... BeFree 24785257 Detail
0.010 colon carcinoma Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer... BeFree 25229241 Detail
0.011 stomach carcinoma In conclusion, this CagA- PI3K/AKT-Sp1-RBP2-Cyclin D1 pathway may serve as a nov... BeFree,GAD 25015565 Detail
0.011 stomach carcinoma Western blot revealed that cyclin D1 and Bcl-2 expression were downregulated whe... BeFree,GAD 25060631 Detail
0.011 stomach carcinoma To examine the expression patterns of ER-α36 and Cyclin D1 in human gastric canc... BeFree,GAD 25231129 Detail
0.011 stomach carcinoma Correlation of RKIP, STAT3 and cyclin D1 expression in pathogenesis of gastric c... BeFree,GAD 25337233 Detail
0.011 stomach carcinoma HIF2α is associated with poor prognosis and affects the expression levels of sur... BeFree,GAD 25338835 Detail
0.011 stomach carcinoma Moreover, the expression of WISP3 was positively correlated with the expression ... BeFree,GAD 25400723 Detail
0.011 stomach carcinoma Fz2 shRNA suppressed cell proliferation and motility of MKN45 and MKN74 cells, a... BeFree,GAD 25586465 Detail
0.011 Carcinoma of bladder Given that the tumor-promoting inflammation has been previously established in s... BeFree,GAD 24448750 Detail
0.011 Carcinoma of bladder All the results demonstrated that miR-576-3p might be a novel suppressor of blad... BeFree,GAD 25556372 Detail
0.011 Carcinoma of bladder Suppression of PHLPP2 or FOXO1 by miR-135a, consisted with dysregulation of p21,... BeFree,GAD 25888950 Detail
0.003 skin carcinoma NA BeFree,GAD Detail
0.003 Central neuroblastoma Cyclin D1 immunohistochemistry was also performed on tissue microarrays of other... BeFree 25751590 Detail
0.004 Malignant neoplasm of kidney NA BeFree,GAD Detail
<0.001 Premenopausal breast cancer NA BeFree Detail
<0.001 Pharyngeal Carcinoma CCND1 amplification was significantly more frequent in pharyngeal carcinomas (63... BeFree 23494454 Detail
<0.001 psychosocial stressor NA BeFree Detail
<0.001 adult acute lymphocytic leukemia NA BeFree Detail
<0.001 lymphangioleiomyomatosis NA BeFree Detail
0.002 Malignant Squamous Cell Neoplasm NA BeFree Detail
<0.001 malignant peripheral nerve sheath tumor NA BeFree Detail
<0.001 Aicardi-Goutieres syndrome 1 NA BeFree Detail
<0.001 Adenomatous polyp of colon NA BeFree Detail
0.002 Invasive breast carcinoma Cyclin D1 is a cell cycle regulatory gene emerging as a potentially significant ... BeFree 25313758 Detail
<0.001 Bile duct cancer resectable NA BeFree Detail
<0.001 Synovial sarcoma metastatic NA BeFree Detail
0.003 Small Lymphocytic Lymphoma NA BeFree Detail
<0.001 Mantle cell lymphoma refractory NA BeFree Detail
<0.001 Advanced cancer NA BeFree Detail
<0.001 Intraepithelial Neoplasia NA BeFree Detail
<0.001 Gastric hyperplastic polyp NA BeFree Detail
0.091 ovarian neoplasm NA BeFree,LHGDN,RGD Detail
<0.001 cancer recurrence NA BeFree Detail
<0.001 Colorectal cancer metastatic NA BeFree Detail
0.001 Hurthle Cell Tumor NA BeFree Detail
0.002 Gastrooesophageal cancer NA GAD Detail
0.002 Invasive Ductal Breast Carcinoma In this study, we attempted to see the expression of Cyclin D1 in invasive ducta... BeFree 25313758 Detail
<0.001 Stage 4S neuroblastoma NA BeFree Detail
<0.001 Plasma cell dyscrasia NA BeFree Detail
0.012 Malignant neoplasm of ovary The down regulation of β-catenin and cyclin-D1 in the tumor tissues may refer to... BeFree,GAD 24444073 Detail
<0.001 endometrial adenocarcinoma NA BeFree Detail
<0.001 Skin toxicity NA BeFree Detail
0.016 Squamous cell carcinoma of the head and neck CCND1 amplification and cyclin D1 immunohistochemical expression in head and nec... BeFree,GAD 23494454 Detail
0.016 Squamous cell carcinoma of the head and neck The current study aims to investigate whether there is a crosstalk between these... BeFree,GAD 23730900 Detail
0.016 Squamous cell carcinoma of the head and neck These findings demonstrate that TRUE gene silencing of cyclin D1 leads to inhibi... BeFree,GAD 25437003 Detail
0.001 Ductal Carcinoma Cyclin D1 expression was seen in 67.5% of ductal carcinoma and it showed a signi... BeFree 25313758 Detail
0.005 sarcoma NA BeFree,LHGDN Detail
<0.001 Lymphocytic infiltration NA BeFree Detail
<0.001 large cell neuroendocrine carcinoma NA BeFree Detail
<0.001 chromophobe renal cell carcinoma NA BeFree Detail
<0.001 Collecting Duct Carcinoma of the Kidney NA BeFree Detail
<0.001 metanephric adenoma Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and meta... BeFree 25751590 Detail
0.003 Solitary fibrous tumor NA LHGDN Detail
<0.001 Atypical teratoid/rhabdoid tumor NA BeFree Detail
<0.001 Cutaneous lymphoma NA BeFree Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
<0.001 atypical polypoid adenomyoma NA BeFree Detail
<0.001 Lymphoma, Primary Cutaneous Anaplastic Large Cell NA BeFree Detail
<0.001 Adenoma of large intestine NA BeFree Detail
0.001 chronic lymphocytic leukemia/small lymphocytic lymphoma NA BeFree Detail
<0.001 ACTH-secreting pituitary adenoma NA BeFree Detail
<0.001 Liver regeneration disorder NA BeFree Detail
<0.001 Adenocarcinoma of large intestine NA BeFree Detail
<0.001 Anterior Tongue Carcinoma Thus, CCND1 overexpression in non-habits associated anterior tongue carcinomas m... BeFree 24809775 Detail
<0.001 Atypical Ductal Breast Hyperplasia NA BeFree Detail
<0.001 congenital mesoblastic nephroma Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and meta... BeFree 25751590 Detail
<0.001 Childhood Renal Neoplasm Cyclin D1 immunohistochemistry was also performed on tissue microarrays of other... BeFree 25751590 Detail
<0.001 Gastric Precancerous Condition NA BeFree Detail
0.001 Hereditary Nonpolyposis Colorectal Cancer NA BeFree Detail
0.002 Invasive Carcinoma NA BeFree Detail
<0.001 Low Grade Ductal Breast Carcinoma In Situ NA BeFree Detail
<0.001 Mature B-Cell Non-Hodgkin Lymphoma NA BeFree Detail
0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
<0.001 Primary Carcinoma NA BeFree Detail
<0.001 Solid pseudopapillary tumour of the pancreas NA BeFree Detail
<0.001 Testicular Germ Cell Tumor NA BeFree Detail
0.001 Marginal Zone B-Cell Lymphoma NA BeFree Detail
<0.001 Burkitt-like lymphoma NA BeFree Detail
0.002 renal carcinoma NA BeFree Detail
<0.001 Primary Lesion NA BeFree Detail
0.001 Cardiomyopathy, Familial Idiopathic NA BeFree Detail
<0.001 Benign melanocytic nevus NA BeFree Detail
0.193 Mammary Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
<0.001 Breast Cancer Model NA BeFree Detail
0.001 Hepatocarcinogenesis NA BeFree Detail
0.001 Mammary Tumorigenesis Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumo... BeFree 25940700 Detail
<0.001 Cancer Cell Growth Cyclin D1 and c-Myc are important regulators of cancer cell growth, and we obser... BeFree 25854169 Detail
<0.001 Malignant Conversion NA BeFree Detail
0.001 Skin Carcinogenesis NA BeFree Detail
<0.001 Xenograft Model NA BeFree Detail
0.068 colorectal cancer The elevated expression of ATG4B was highly correlated with CCND1 expression, co... BeFree,GAD 24991826 Detail
0.068 colorectal cancer Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorecta... BeFree,GAD 25146682 Detail
0.068 colorectal cancer Treatment with ganetespib (50 nM) for 24 hours inhibited cyclin D1 and pRb at th... BeFree,GAD 25296971 Detail
0.068 colorectal cancer Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of t... BeFree,GAD 25479723 Detail
0.068 colorectal cancer The significant association of CCND1 genotypes with colorectal cancer in Taiwan. BeFree,GAD 25809706 Detail
0.068 colorectal cancer Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase ... BeFree,GAD 25818893 Detail
0.068 colorectal cancer The quantitative level of the β-catenin protein was significantly decreased in t... BeFree,GAD 26316447 Detail
<0.001 Ductal Breast Carcinoma Cyclin D1 expression in ductal carcinoma of the breast and its correlation with ... BeFree 25313758 Detail
<0.001 Ductal Breast Carcinoma The biological mechanism of CCND1 in carcinogenesis has not been fully examined;... BeFree 25470788 Detail
<0.001 smoldering myeloma NA BeFree Detail
<0.001 Cirrhosis NA BeFree Detail
<0.001 androgen independent prostate cancer NA BeFree Detail
<0.001 Peripheral Arterial Diseases NA BeFree Detail
<0.001 Keratocystic Odontogenic Tumor Overexpression of upstream (PTCH1 and SMO) and downstream (GLI1, CCND1 and BCL2)... BeFree 24930892 Detail
0.397 multiple myeloma The CCND1 c.870G&gt;A polymorphism is a risk factor for t(11;14)(q13;q32) multip... GWASCAT 23502783 Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
<0.001 Papillary Thyroid Microcarcinoma NA BeFree Detail
<0.001 Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type Solely the expression of cyclin D1 (100%) and the presence of t(11;14) (100%) al... BeFree 26034867 Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
0.003 Idiopathic Pulmonary Fibrosis NA BeFree,LHGDN Detail
<0.001 MYELOPROLIFERATIVE SYNDROME, TRANSIENT Aberrant nuclear β-catenin expression, detected in all MSTs, appears to be the r... BeFree 26200099 Detail
<0.001 Hyperparathyroidism 1 NA BeFree Detail
<0.001 MULTICYSTIC RENAL DYSPLASIA, BILATERAL NA BeFree Detail
<0.001 ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1 NA BeFree Detail
<0.001 HYPERTRICHOSIS, CONGENITAL GENERALIZED NA BeFree Detail
<0.001 TUBEROUS SCLEROSIS 2 (disorder) NA BeFree Detail
<0.001 HYPERPARATHYROIDISM 3 NA BeFree Detail
0.002 uterine corpus cancer NA BeFree Detail
<0.001 Lymphoma, Follicular, Grade 1 NA BeFree Detail
<0.001 coronary artery disease NA BeFree Detail
0.003 Cardiac Carcinoma NA BeFree,GAD Detail
<0.001 plasma cell neoplasm NA BeFree Detail
<0.001 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma NA BeFree Detail
0.007 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree,GAD Detail
0.004 Leukemia, B-Cell NA BeFree,LHGDN Detail
<0.001 Urothelial Carcinoma Given that the tumor-promoting inflammation has been previously established in s... BeFree 24448750 Detail
<0.001 malignant neoplasm of breast staging NA BeFree Detail
0.147 liver carcinoma The bFGF-stimulated activation of protein kinase B (AKT) and extracellular signa... BeFree,CTD_human,GAD,LHGDN 24970807 Detail
0.147 liver carcinoma Small interfering RNA (siRNA)-mediated knockdown of macrophage migration inhibit... BeFree,CTD_human,GAD,LHGDN 25015194 Detail
0.147 liver carcinoma Expression and significance of Pin1, β-catenin and cyclin D1 in hepatocellular c... BeFree,CTD_human,GAD,LHGDN 25109821 Detail
0.147 liver carcinoma In addition, these findings were further strengthened by results showing that ex... BeFree,CTD_human,GAD,LHGDN 25313882 Detail
0.147 liver carcinoma Annexin A2 knockdown inhibits hepatoma cell growth and sensitizes hepatoma cells... BeFree,CTD_human,GAD,LHGDN 25385370 Detail
0.147 liver carcinoma Both sorafenib and ATO downregulated the expression of cyclin D1, resulting in H... BeFree,CTD_human,GAD,LHGDN 25416439 Detail
<0.001 Endometrial stromal sarcoma, high grade NA BeFree Detail
<0.001 bulimia nervosa NA BeFree Detail
<0.001 Oropharyngeal Carcinoma NA BeFree Detail
<0.001 Adrenal incidentaloma NA BeFree Detail
<0.001 Steatohepatitis NA BeFree Detail
<0.001 Lentigo maligna melanoma NA BeFree Detail
<0.001 Promyelocytic leukemia NA BeFree Detail
<0.001 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C NA BeFree Detail
0.002 Chronic ulcerative colitis NA GAD Detail
0.125 Nasopharyngeal carcinoma Alterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in r... BeFree,CTD_human 25109634 Detail
0.125 Nasopharyngeal carcinoma Cyclin D1 G870A polymorphism and risk of nasopharyngeal carcinoma: a case-contro... BeFree,CTD_human 25409185 Detail
<0.001 Clear-cell metastatic renal cell carcinoma NA BeFree Detail
0.002 Prostatic Hyperplasia NA GAD Detail
<0.001 Endometrial sarcoma This translocation also occurs in high-grade endometrial sarcoma, in which it is... BeFree 25751590 Detail
<0.001 Bisphosphonate-associated osteonecrosis NA BeFree Detail
<0.001 Early-Stage Breast Carcinoma NA BeFree Detail
<0.001 Esophageal Spindle Cell Carcinoma NA BeFree Detail
<0.001 Palisaded myofibroblastoma NA BeFree Detail
0.003 myelodysplastic syndrome NA LHGDN Detail
<0.001 Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor NA BeFree Detail
<0.001 Melanocytic nevus of skin NA BeFree Detail
<0.001 Mammary adenocarcinoma Sustained expression of cyclin D1(KE) induced mammary adenocarcinoma with simila... BeFree 25940700 Detail
<0.001 Fibromyxosarcoma NA BeFree Detail
0.001 Experimental Organism Basal Cell Carcinoma NA BeFree Detail
<0.001 Apert syndrome NA BeFree Detail
0.024 adenocarcinoma NA BeFree,GAD,LHGDN Detail
0.011 adenoma Western blot and immunohistochemical analysis also demonstrated higher expressio... BeFree,LHGDN 24510244 Detail
<0.001 Alzheimer's disease Cyclin D1 positive neurons are colocalized with AGEs or directly surrounded by e... BeFree 25448604 Detail
<0.001 ameloblastoma Overexpression of upstream (PTCH1 and SMO) and downstream (GLI1, CCND1 and BCL2)... BeFree 24930892 Detail
<0.001 Anaplasia NA BeFree Detail
0.003 Anoxia NA LHGDN Detail
<0.001 Anus Neoplasms NA BeFree Detail
<0.001 Anxiety Disorders NA BeFree Detail
<0.001 rheumatoid arthritis NA BeFree Detail
<0.001 asthma Bcl1 polymorphism of glucocorticoids receptor gene and bronchial asthma. BeFree 25879559 Detail
0.001 Astrocytoma NA BeFree Detail
<0.001 ataxia telangiectasia NA BeFree Detail
0.003 Barrett esophagus NA BeFree,GAD Detail
<0.001 Basal Cell Nevus Syndrome NA BeFree Detail
<0.001 Benign Ovarian Neoplasm NA BeFree Detail
0.027 Malignant neoplasm of urinary bladder All the results demonstrated that miR-576-3p might be a novel suppressor of blad... BeFree,GAD 25556372 Detail
0.027 Malignant neoplasm of urinary bladder Suppression of PHLPP2 or FOXO1 by miR-135a, consisted with dysregulation of p21,... BeFree,GAD 25888950 Detail
0.010 Bladder Neoplasm NA BeFree,GAD,LHGDN Detail
0.123 Brain Neoplasms NA BeFree,CTD_human,GAD Detail
0.106 Malignant neoplasm of breast Here, we demonstrate that two different ERβ agonists, WAY-20070 and a novel A-CD... BeFree,GAD 24785256 Detail
0.106 Malignant neoplasm of breast Cyclin D1/CDK4 activity is upregulated in up to 50% of breast cancers and CDK4-m... BeFree,GAD 25006666 Detail
0.106 Malignant neoplasm of breast Transcriptional CCND1 expression as a predictor of poor response to neoadjuvant ... BeFree,GAD 25200445 Detail
0.106 Malignant neoplasm of breast The high or moderate expressions of breast cancer markers (VEGF, c-Myc and cycli... BeFree,GAD 25230850 Detail
0.106 Malignant neoplasm of breast We found that TBLR1 expression was implicated in the upregulation of cyclin D1, ... BeFree,GAD 25341494 Detail
0.106 Malignant neoplasm of breast Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA... BeFree,GAD 25363551 Detail
0.106 Malignant neoplasm of breast Genetic association between cyclin D1 polymorphism and breast cancer susceptibil... BeFree,GAD 25399071 Detail
0.106 Malignant neoplasm of breast Estrogen receptor-α drives adiponectin effects on cyclin D1 expression in breast... BeFree,GAD 25657113 Detail
0.106 Malignant neoplasm of breast We initiated the following study to directly test the oncogenic potential of cat... BeFree,GAD 25940700 Detail
0.106 Malignant neoplasm of breast Genetic polymorphisms in cell cycle regulatory genes CCND1 and CDK4 are associat... BeFree,GAD 26416047 Detail
<0.001 Burkitt lymphoma NA BeFree Detail
0.009 Malignant tumor of colon Analyses of human colon cancer databases also demonstrated a link between miR26b... BeFree 24785257 Detail
0.009 Malignant tumor of colon Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer... BeFree 25229241 Detail
0.002 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 female breast carcinoma NA BeFree Detail
0.007 Malignant neoplasm of larynx NA BeFree,GAD Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of skin NA BeFree Detail
<0.001 Malignant neoplasm of thyroid Cyclin D1 and c-Myc are important regulators of cancer cell growth, and we obser... BeFree 25854169 Detail
<0.001 Bronchioloalveolar Adenocarcinoma NA BeFree Detail
0.004 Noninfiltrating Intraductal Carcinoma NA BeFree Detail
0.011 Non-small cell lung carcinoma Interestingly, DDX5 and cyclin D1 expression followed positive correlation in th... BeFree,GAD 26212035 Detail
<0.001 Carcinoma, Papillary NA BeFree Detail
0.004 renal cell carcinoma The effect of downregulation of tNASP by siRNA on cell colony formation and prol... BeFree 25669170 Detail
Annotation

Annotations

DescrptionSourceLinks
Cyclin D1 overexpression is associated with poor clinicopathological outcome and survival in oral sq... DisGeNET Detail
Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the... DisGeNET Detail
Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The elevated expression of ATG4B was highly correlated with CCND1 expression, consistently supportin... DisGeNET Detail
Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibil... DisGeNET Detail
Treatment with ganetespib (50 nM) for 24 hours inhibited cyclin D1 and pRb at the transcriptional an... DisGeNET Detail
Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in huma... DisGeNET Detail
The significant association of CCND1 genotypes with colorectal cancer in Taiwan. DisGeNET Detail
Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase 2) have reported to ... DisGeNET Detail
The quantitative level of the β-catenin protein was significantly decreased in the CRC cell lysates,... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In conclusion, the expression of Cav-1 was downregulated in CRS and the role of Cav-1 was impaired i... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to milnacipran and fluv... DisGeNET Detail
Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to milnacipran and fluv... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The mitotic index and immunoreactivity of NF-kB, phospho-IkB, and cyclin D1 in the center of 28 larg... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Activation of FOXO1 and 3a and a decreased expression of their target gene Cyclin D1 were also obser... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Annexin A2 knockdown inhibits hepatoma cell growth and sensitizes hepatoma cells to 5-fluorouracil b... DisGeNET Detail
NA DisGeNET Detail
In addition, we determined the expression patterns of connective tissue growth factor (CTGF) and cyc... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Two cyclin D1-positive lymphomas with morphologic features of DLBCL and IGH-CCND1 translocations wer... DisGeNET Detail
We present here a unique case of follicular lymphoma (FL) with rearranged BCL2, BCL6, and BCL1 (also... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In conclusion, this CagA- PI3K/AKT-Sp1-RBP2-Cyclin D1 pathway may serve as a novel mechanism for gas... DisGeNET Detail
To examine the expression patterns of ER-α36 and Cyclin D1 in human gastric cancer tissues and to in... DisGeNET Detail
Correlation of RKIP, STAT3 and cyclin D1 expression in pathogenesis of gastric cancer. DisGeNET Detail
Moreover, the expression of WISP3 was positively correlated with the expression of cyclin D1 and TCF... DisGeNET Detail
Fz2 shRNA suppressed cell proliferation and motility of MKN45 and MKN74 cells, and downregulated cyc... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
FISH analysis of human acral melanoma expanding in the epidermis revealed that unpigmented melanobla... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
An association between CCND1 overexpression in oral tumors and poor prognosis has previously been re... DisGeNET Detail
We showed tetraspanins attenuated peIF4E and its targets [c‑Myc, cyclin D1 (cycD1)]; eIF4E attenuati... DisGeNET Detail
Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Head and neck squamous cell carcinoma (HNSCC) progression and metastasis have previously been associ... DisGeNET Detail
The pooled results provided compelling evidence that cyclin D1 overexpression was significantly corr... DisGeNET Detail
RKIP expression in gastric cancer was negatively correlated with the invasion, TNM stage and lymphoi... DisGeNET Detail
To elucidate the underlying molecular mechanisms produced by these EDC, alterations in transcription... DisGeNET Detail
Our results suggest that the CCND1 A870G polymorphism might not be a potential candidate for predict... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and metanephric adenoma and ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry was also performed on tissue microarrays of other pediatric renal tum... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
β-catenin protein expression was, however, detected in the membrane and cytoplasm of 69.6% (32/46) o... DisGeNET Detail
When HMGN2 expression was enhanced, the expression of cyclin D1 and PCNA was downregulated in osteos... DisGeNET Detail
The cyclin D1 expression was significantly decreased following the treatment with quercetin in SKOV3... DisGeNET Detail
The down regulation of β-catenin and cyclin-D1 in the tumor tissues may refer to the inhibition of S... DisGeNET Detail
The cyclin D1 expression was significantly decreased following the treatment with quercetin in SKOV3... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Discordant results were observed for VEGFR1, p27, and p21 overexpressed in paragangliomas but undere... DisGeNET Detail
NA DisGeNET Detail
While bi-allelic inactivation of CDC73/HRPT2 seems unique to parathyroid malignancy, aberrant activa... DisGeNET Detail
We observed that Ad-HDAC2 shRNA decreased inflammatory cell infiltration, reduced transnuclear expre... DisGeNET Detail
Overexpression of the SMAD7 gene decreased the expression of cyclin D1 (a positive cell cycle regula... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Further studies in premalignant bronchial cells showed that the antiproliferative effects of I3C + S... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Following further examination of cell cycle-related factors, MCM2 knockdown inhibited protein retino... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
RKIP, STAT3 and cyclin D1 proteins were detected by immunohistochemistry in tissues of gastric ulcer... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Mantle cell lymphoma (MCL) is a unique subtype of B-cell non-Hodgkin's lymphoma characterized by chr... DisGeNET Detail
NA DisGeNET Detail
Cyclin D1-positive diffuse large B-cell lymphoma with IGH-CCND1 translocation and BCL6 rearrangement... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Furthermore, suppressed CCND1 and elevated caspase3 and caspase7 expression levels at mRNA were foun... DisGeNET Detail
Furthermore, HMC-1 exosomes contain and transfer KIT protein, but not the c-KIT mRNA to A549 cells a... DisGeNET Detail
NA DisGeNET Detail
The increased expression of pS(21)GSK3α and pS(9)GSK3β not only correlated positively with cyclin D1... DisGeNET Detail
We used the odds ratio (OR) and hazard ratio (HR) as the common measures of association to quantitat... DisGeNET Detail
The expression of total and phosphorylated GSK3α/β as well as cyclin D1 and p53 together with their ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and metanephric adenoma and ... DisGeNET Detail
Furthermore, YWHAE-NUTM2 ESSs are strongly cyclin D1 positive in contrast to conventional low-grade ... DisGeNET Detail
This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyc... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and metanephric adenoma and ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Collectively, our results indicate that let-7b overexpression can in turn downregulate cyclin D1 exp... DisGeNET Detail
We used the odds ratio (OR) and hazard ratio (HR) as the common measures of association to quantitat... DisGeNET Detail
The expression of total and phosphorylated GSK3α/β as well as cyclin D1 and p53 together with their ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MiR-219-1-3p overexpression (transient and stable) in pancreatic cancer cell lines induced a decreas... DisGeNET Detail
WNT5A, p-AKT and Cyclin D1 were highly expressed in pancreatic cancer tissues, and the WNT5A express... DisGeNET Detail
Cyclin D1 is a strong prognostic factor for survival in pancreatic cancer: analysis of CD G870A poly... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
A cyclin D1 (CCND1) gene polymorphism contributes to susceptibility to papillary thyroid cancer in t... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
A multivariate analysis revealed that the NR3C1 Bcl1 G allele was a significant risk factor for the ... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
NA DisGeNET Detail
Recently, we demonstrated that PML interacted with nuclear EGFR (nEGFR) and suppressed the nEGFR-med... DisGeNET Detail
These effects may result from the ability of miR-5100 to promote G1/S transition and downregulate cy... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The purpose of this study was to identify interacting signaling pathways by which the activation of ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1-induced proliferation is independent of beta-catenin in head and neck cancer. DisGeNET Detail
Association of cyclin D1 variants with head and neck cancer susceptibility: evidence from a meta-ana... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 level correlated with Pin1 expression in clinical ESCC specimens. DisGeNET Detail
NA DisGeNET Detail
The expressions of p21, p27, bcl-2, bcl-6 and cyclin D1 were not significant prognostic factors for ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Mantle cell lymphoma (MCL) is a unique subtype of B-cell non-Hodgkin's lymphoma characterized by chr... DisGeNET Detail
Fluorescence in situ hybridization in MCL cells showed that t(11;14)(q13;q32) results in detachment ... DisGeNET Detail
Mantle cell lymphoma is molecularly characterized by the chromosomal translocation t(11;14) (q13;q32... DisGeNET Detail
Our study demonstrates convincingly that IGH-CCND1 rearrangement leading to cyclin D1 overexpression... DisGeNET Detail
Interestingly, depletion of JARID1B inhibits Cyclin D1, which is one of the genes contributes to MCL... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Since cyclin D1 is a key regulator of cell cycle G1/S phase progression essential for proliferation,... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Analyses of human colon cancer databases also demonstrated a link between miR26b and LEF1 expression... DisGeNET Detail
NA DisGeNET Detail
MiR-219-1-3p overexpression (transient and stable) in pancreatic cancer cell lines induced a decreas... DisGeNET Detail
WNT5A, p-AKT and Cyclin D1 were highly expressed in pancreatic cancer tissues, and the WNT5A express... DisGeNET Detail
Cyclin D1 is a strong prognostic factor for survival in pancreatic cancer: analysis of CD G870A poly... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The expression of prostate cancer-associated genes, including cyclin D1, IL-6, COX2, and ETV1, was b... DisGeNET Detail
Formononetin could exhibit inhibitory activity against human prostate cancer cells in vivo and in vi... DisGeNET Detail
Moreover, our data suggest that TRAF6-mediated Lys63-linked ubiquitination of the TβRI intracellular... DisGeNET Detail
Effect of the CCND1 A870G polymorphism on prostate cancer risk: a meta-analysis of 3,820 cases and 3... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 and c-Myc are important regulators of cancer cell growth, and we observed that treatment o... DisGeNET Detail
Prognostic significance of miR-34a in Ewing sarcoma is associated with cyclin D1 and ki-67 expressio... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
CCND1 and DACT3 overexpression in non-habits associated tongue carcinomas were subsequently validate... DisGeNET Detail
The increased expression of pS(21)GSK3α and pS(9)GSK3β not only correlated positively with cyclin D1... DisGeNET Detail
β-catenin protein expression was, however, detected in the membrane and cytoplasm of 69.6% (32/46) o... DisGeNET Detail
When HMGN2 expression was enhanced, the expression of cyclin D1 and PCNA was downregulated in osteos... DisGeNET Detail
The cyclin D1 expression was significantly decreased following the treatment with quercetin in SKOV3... DisGeNET Detail
NA DisGeNET Detail
Western blotting analysis demonstrated that tumorigenesis related protein cyclin D1 and p21, as well... DisGeNET Detail
Cyclin D1 (CCND1) and E-cadherin (CDH1) are two important genes of the β-catenin/LEF pathway that is... DisGeNET Detail
AP-1 transcriptional activity was analyzed with a luciferase reporter and bioluminescence imaging, a... DisGeNET Detail
This study aimed to investigate the correlation of RKIP, STAT3 and cyclin D1 expression in the tumor... DisGeNET Detail
The biological mechanism of CCND1 in carcinogenesis has not been fully examined; but at present Cycl... DisGeNET Detail
Cyclin D1 (CCND1) regulating cell cycle transition may determine the susceptible individuals to geno... DisGeNET Detail
Cyclin D1 (CCND1) is critical in the transition of the cell cycle from the G1 to S phases, and unbal... DisGeNET Detail
Aberrant nuclear β-catenin expression, detected in all MSTs, appears to be the result of stabilizing... DisGeNET Detail
This study was performed to screen cyclin D1 (CCND1) and cyclin dependent kinases (CDK4) genes in or... DisGeNET Detail
Furthermore, we demonstrate that PRMT5 overexpression specifically cooperates with cyclin D1 to driv... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 expression in prostate carcinoma. DisGeNET Detail
The expression of prostate cancer-associated genes, including cyclin D1, IL-6, COX2, and ETV1, was b... DisGeNET Detail
Formononetin could exhibit inhibitory activity against human prostate cancer cells in vivo and in vi... DisGeNET Detail
Moreover, our data suggest that TRAF6-mediated Lys63-linked ubiquitination of the TβRI intracellular... DisGeNET Detail
Effect of the CCND1 A870G polymorphism on prostate cancer risk: a meta-analysis of 3,820 cases and 3... DisGeNET Detail
NA DisGeNET Detail
miR-211 suppresses epithelial ovarian cancer proliferation and cell-cycle progression by targeting C... DisGeNET Detail
The cyclin D1 expression was significantly decreased following the treatment with quercetin in SKOV3... DisGeNET Detail
NA DisGeNET Detail
Here, we demonstrate that two different ERβ agonists, WAY-20070 and a novel A-CD estrogen called L17... DisGeNET Detail
Cyclin D1/CDK4 activity is upregulated in up to 50% of breast cancers and CDK4-mediated phosphorylat... DisGeNET Detail
Transcriptional CCND1 expression as a predictor of poor response to neoadjuvant chemotherapy with tr... DisGeNET Detail
We found that TBLR1 expression was implicated in the upregulation of cyclin D1, phosphorylation of c... DisGeNET Detail
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 ... DisGeNET Detail
Genetic association between cyclin D1 polymorphism and breast cancer susceptibility. DisGeNET Detail
Estrogen receptor-α drives adiponectin effects on cyclin D1 expression in breast cancer cells. DisGeNET Detail
We initiated the following study to directly test the oncogenic potential of catalytically inactive ... DisGeNET Detail
Genetic polymorphisms in cell cycle regulatory genes CCND1 and CDK4 are associated with susceptibili... DisGeNET Detail
Recently, we demonstrated that PML interacted with nuclear EGFR (nEGFR) and suppressed the nEGFR-med... DisGeNET Detail
These effects may result from the ability of miR-5100 to promote G1/S transition and downregulate cy... DisGeNET Detail
In addition, amplification of CCND1 shows a negative predictive value of 80 % in the detection of LN... DisGeNET Detail
Copy number variation in CCND1 gene is implicated in the pathogenesis of sporadic parathyroid carcin... DisGeNET Detail
NA DisGeNET Detail
Analyses of human colon cancer databases also demonstrated a link between miR26b and LEF1 expression... DisGeNET Detail
Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer. DisGeNET Detail
In conclusion, this CagA- PI3K/AKT-Sp1-RBP2-Cyclin D1 pathway may serve as a novel mechanism for gas... DisGeNET Detail
Western blot revealed that cyclin D1 and Bcl-2 expression were downregulated whereas p27 and Bax wer... DisGeNET Detail
To examine the expression patterns of ER-α36 and Cyclin D1 in human gastric cancer tissues and to in... DisGeNET Detail
Correlation of RKIP, STAT3 and cyclin D1 expression in pathogenesis of gastric cancer. DisGeNET Detail
HIF2α is associated with poor prognosis and affects the expression levels of survivin and cyclin D1 ... DisGeNET Detail
Moreover, the expression of WISP3 was positively correlated with the expression of cyclin D1 and TCF... DisGeNET Detail
Fz2 shRNA suppressed cell proliferation and motility of MKN45 and MKN74 cells, and downregulated cyc... DisGeNET Detail
Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
All the results demonstrated that miR-576-3p might be a novel suppressor of bladder cancer cell prol... DisGeNET Detail
Suppression of PHLPP2 or FOXO1 by miR-135a, consisted with dysregulation of p21, p27, Cyclin D1 and ... DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry was also performed on tissue microarrays of other pediatric renal tum... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
CCND1 amplification was significantly more frequent in pharyngeal carcinomas (63%) than in laryngeal... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 is a cell cycle regulatory gene emerging as a potentially significant oncogene in invasive... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In this study, we attempted to see the expression of Cyclin D1 in invasive ductal carcinomas of the ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The down regulation of β-catenin and cyclin-D1 in the tumor tissues may refer to the inhibition of S... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
CCND1 amplification and cyclin D1 immunohistochemical expression in head and neck squamous cell carc... DisGeNET Detail
The current study aims to investigate whether there is a crosstalk between these pathways in HNSCC a... DisGeNET Detail
These findings demonstrate that TRUE gene silencing of cyclin D1 leads to inhibition of the growth o... DisGeNET Detail
Cyclin D1 expression was seen in 67.5% of ductal carcinoma and it showed a significant correlation w... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and metanephric adenoma and ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Thus, CCND1 overexpression in non-habits associated anterior tongue carcinomas may contribute to the... DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 immunohistochemistry helps distinguish CCSK from blastemal WT and metanephric adenoma and ... DisGeNET Detail
Cyclin D1 immunohistochemistry was also performed on tissue microarrays of other pediatric renal tum... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis. DisGeNET Detail
Cyclin D1 and c-Myc are important regulators of cancer cell growth, and we observed that treatment o... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The elevated expression of ATG4B was highly correlated with CCND1 expression, consistently supportin... DisGeNET Detail
Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibil... DisGeNET Detail
Treatment with ganetespib (50 nM) for 24 hours inhibited cyclin D1 and pRb at the transcriptional an... DisGeNET Detail
Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in huma... DisGeNET Detail
The significant association of CCND1 genotypes with colorectal cancer in Taiwan. DisGeNET Detail
Additionally, CCND1 (cyclin D1), and PTGS2 (prostaglandin-endoperoxide synthase 2) have reported to ... DisGeNET Detail
The quantitative level of the β-catenin protein was significantly decreased in the CRC cell lysates,... DisGeNET Detail
Cyclin D1 expression in ductal carcinoma of the breast and its correlation with other prognostic par... DisGeNET Detail
The biological mechanism of CCND1 in carcinogenesis has not been fully examined; but at present Cycl... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Overexpression of upstream (PTCH1 and SMO) and downstream (GLI1, CCND1 and BCL2) genes in the SHH pa... DisGeNET Detail
The CCND1 c.870G&gt;A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Solely the expression of cyclin D1 (100%) and the presence of t(11;14) (100%) allowed a distinction ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Aberrant nuclear β-catenin expression, detected in all MSTs, appears to be the result of stabilizing... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
NA DisGeNET Detail
The bFGF-stimulated activation of protein kinase B (AKT) and extracellular signal-regulated kinase (... DisGeNET Detail
Small interfering RNA (siRNA)-mediated knockdown of macrophage migration inhibitory factor (MIF) sup... DisGeNET Detail
Expression and significance of Pin1, β-catenin and cyclin D1 in hepatocellular carcinoma. DisGeNET Detail
In addition, these findings were further strengthened by results showing that expression of FZD7 was... DisGeNET Detail
Annexin A2 knockdown inhibits hepatoma cell growth and sensitizes hepatoma cells to 5-fluorouracil b... DisGeNET Detail
Both sorafenib and ATO downregulated the expression of cyclin D1, resulting in HCC cells arrested at... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Alterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in radioresistant nasoph... DisGeNET Detail
Cyclin D1 G870A polymorphism and risk of nasopharyngeal carcinoma: a case-control study and meta-ana... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyc... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Sustained expression of cyclin D1(KE) induced mammary adenocarcinoma with similar kinetics to that o... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Western blot and immunohistochemical analysis also demonstrated higher expression of CCND1 in carcin... DisGeNET Detail
Cyclin D1 positive neurons are colocalized with AGEs or directly surrounded by extracellular AGE dep... DisGeNET Detail
Overexpression of upstream (PTCH1 and SMO) and downstream (GLI1, CCND1 and BCL2) genes in the SHH pa... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Bcl1 polymorphism of glucocorticoids receptor gene and bronchial asthma. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
All the results demonstrated that miR-576-3p might be a novel suppressor of bladder cancer cell prol... DisGeNET Detail
Suppression of PHLPP2 or FOXO1 by miR-135a, consisted with dysregulation of p21, p27, Cyclin D1 and ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Here, we demonstrate that two different ERβ agonists, WAY-20070 and a novel A-CD estrogen called L17... DisGeNET Detail
Cyclin D1/CDK4 activity is upregulated in up to 50% of breast cancers and CDK4-mediated phosphorylat... DisGeNET Detail
Transcriptional CCND1 expression as a predictor of poor response to neoadjuvant chemotherapy with tr... DisGeNET Detail
The high or moderate expressions of breast cancer markers (VEGF, c-Myc and cyclin D1) in mammary can... DisGeNET Detail
We found that TBLR1 expression was implicated in the upregulation of cyclin D1, phosphorylation of c... DisGeNET Detail
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 ... DisGeNET Detail
Genetic association between cyclin D1 polymorphism and breast cancer susceptibility. DisGeNET Detail
Estrogen receptor-α drives adiponectin effects on cyclin D1 expression in breast cancer cells. DisGeNET Detail
We initiated the following study to directly test the oncogenic potential of catalytically inactive ... DisGeNET Detail
Genetic polymorphisms in cell cycle regulatory genes CCND1 and CDK4 are associated with susceptibili... DisGeNET Detail
NA DisGeNET Detail
Analyses of human colon cancer databases also demonstrated a link between miR26b and LEF1 expression... DisGeNET Detail
Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Cyclin D1 and c-Myc are important regulators of cancer cell growth, and we observed that treatment o... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Interestingly, DDX5 and cyclin D1 expression followed positive correlation in the same set of NSCLC ... DisGeNET Detail
NA DisGeNET Detail
The effect of downregulation of tNASP by siRNA on cell colony formation and proliferation was examin... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386493716 dbSNP
Genome
hg38
Position
chr11:69,641,156-69,654,474
Variant Type
snv
Genome browser