Annotation Detail

Information
Associated Genes
CCND1
Associated Variants
CCND1 MUTATION
CCND1 MUTATION
Associated Disease
tongue carcinoma
Source Database
DisGeNET
Description
The increased expression of pS(21)GSK3α and pS(9)GSK3β not only correlated positively with cyclin D1 and p53 expression in tongue cancer progression but a gradual shift of their expression from the cytoplasmic to the nuclear compartment and overall disease severity was also observed.
Pubmed
25645517
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs