Annotation Detail
Information
- Associated Genes
- CCND1
- Associated Variants
-
CCND1 MUTATION
CCND1 MUTATION - Associated Disease
- Adenocarcinoma of lung (disorder)
- Source Database
- DisGeNET
- Description
- Furthermore, suppressed CCND1 and elevated caspase3 and caspase7 expression levels at mRNA were found in this study, indicating that shikonin may inhibit the growth of lung adenocarcinoma cell by changing cell cycle and promoting cell apoptosis through the regulation of CCND1, caspase3, and caspase7.
- Pubmed
- 24972691
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs