Richter's syndrome (Cancer)
Information
- Disease name
- Richter's syndrome
- Disease ID
- DOID:1703
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02029443 | Active, not recruiting | Phase 1/Phase 2 | ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia | January 30, 2014 | September 6, 2027 |
| NCT02362035 | Active, not recruiting | Phase 1/Phase 2 | ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies | February 20, 2015 | April 1, 2026 |
| NCT03263637 | Completed | Phase 1 | Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies | October 24, 2017 | September 30, 2021 |
| NCT01171378 | Completed | Phase 2 | Study of Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone (CHOP) With Ofatumumab in Patients With Richter's Syndrome | April 2011 | April 19, 2016 |
| NCT03113695 | Completed | Phase 1 | Obinutuzumab, High Dose Methylprednisolone (HDMP), and Lenalidomide for the Treatment of Patients With Richter's Syndrome | December 20, 2017 | May 2, 2022 |
| NCT04623541 | Recruiting | Phase 1/Phase 2 | Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome | November 25, 2020 | August 2029 |
| NCT04939363 | Recruiting | Phase 2 | A Study to Evaluate the Efficacy and Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Patients With Richter's Syndrome; | August 8, 2021 | September 10, 2024 |
| NCT05665530 | Recruiting | Phase 1 | A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib in Participants With R/R Hematologic Malignancies | September 12, 2023 | April 2025 |
- Disase is a (Disease Ontology)
- DOID:1040
- Cross Reference ID (Disease Ontology)
- GARD:7578
- Cross Reference ID (Disease Ontology)
- ICD10CM:C91.1
- Cross Reference ID (Disease Ontology)
- NCI:C35424
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:277550009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0349631
- Exact Synonym (Disease Ontology)
- Richter syndrome