hyperparathyroidism
Information
- Disease name
- hyperparathyroidism
- Disease ID
- DOID:13543
- Description
- "A parathyroid gland disease characterized by an overactivity of the parathyroid glands, leading to an excess of parathyroid hormone in the body." [url:http\://en.wikipedia.org/wiki/Hyperparathyroidism, url:http\://ghr.nlm.nih.gov/glossary=hyperparathyroidism]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| CDC73 | 1 | 193,122,031 | 193,254,815 | 4 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03747029 | Completed | Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study | November 28, 2017 | December 31, 2018 | |
| NCT00004843 | Completed | N/A | A Randomized Study of Surgery vs No Surgery in Patients With Mild Asymptomatic Primary Hyperparathyroidism | April 1997 | March 30, 1999 |
| NCT00006329 | Completed | Phase 2/Phase 3 | Comparison of Two Methods of Parathyroidectomy for Primary Hyperparathyroidism | ||
| NCT00037518 | Completed | Phase 4 | A Study of an Investigational Medication for Severe Primary Hyperparathyroidism or Parathyroid Cancer | April 2001 | |
| NCT01573520 | Completed | Phase 4 | Treatment Adhesion in Dialysis Patients Treated With Cinacalcet | January 2010 | November 2011 |
| NCT01640184 | Completed | N/A | Efficacy and Safety of Ultrasonic Ablation to Treat Secondary Hyperparathyroidism in Chronic Kidney Disease Patients | August 2012 | November 2014 |
| NCT01656070 | Completed | Phase 2 | Vitamin D Supplementation in HIV-infected Youth | April 2011 | July 2012 |
| NCT01691781 | Completed | N/A | The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study | October 2012 | December 2016 |
| NCT01872429 | Completed | Short- and Long-Term Impact of Subtotal Parathyroidectomy on the Achievement of Bone and Mineral Parameters Recommended by Clinical Practice Guidelines in Dialysis Patients | November 2012 | April 2013 | |
| NCT01935856 | Completed | Phase 1/Phase 2 | Phase 1/2 Study of KHK7580 for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis | August 2013 | March 2014 |
| NCT02205801 | Completed | N/A | Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy | July 2014 | February 17, 2017 |
| NCT02432599 | Completed | Phase 2 | Interest of the F18-choline as a Second Line of the Tracer for Detection of Parathyroid Adenomas | March 2015 | February 2017 |
| NCT02524041 | Completed | N/A | Association Between Serum Periostin Levels and Cortical Porosity in Patients With Secondary Hyperparathyroidism | March 2014 | April 2016 |
| NCT02591160 | Completed | N/A | Optimal HCTZ Cessation for Diagnosis of Hyperparathyroidism | May 2015 | September 13, 2017 |
| NCT02747979 | Completed | Phase 2/Phase 3 | The Effect and Safety of Hemodialysis and Hemoperfusion on Severe Renal Osteopathy and Itching in Uremia Patients | April 2009 | May 2010 |
| NCT03027349 | Completed | Serum Calcium to Phosphorous Ratio (Ca/P) as a Simple, Inexpensive Screening Tool in the Diagnosis of Primary Hyperparathyroidism | January 2011 | February 2017 | |
| NCT00001277 | Completed | Phase 2 | Studies of Elevated Parathyroid Activity | December 15, 1993 | December 23, 2020 |
| NCT03968510 | Completed | Swalqol in Primary Hyperparathyroidism | November 1, 2018 | November 1, 2020 | |
| NCT04040946 | Completed | Phase 3 | Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention | September 19, 2019 | June 30, 2023 |
| NCT04316845 | Completed | N/A | 18F-fluorocholine PET/CT for Hyperparathyroidism | January 16, 2018 | December 31, 2019 |
| NCT04570033 | Completed | N/A | The Utility of 18F-fluorocholine PET/CT in the Imaging of Parathyroid Adenomas | January 1, 2016 | January 1, 2020 |
| NCT04671719 | Completed | Determination of Circulating Autotaxin in Patients With GNAS or PTH Abnormalities | March 10, 2021 | January 11, 2023 | |
| NCT05346419 | Completed | N/A | Antiresorptive Effect of Treatment With Risedronate and Vitamin D in Postmenopausal Patients | July 1, 2021 | February 26, 2022 |
| NCT05696405 | Completed | VATS for Resection of Mediastinal Parathyroids | January 1, 2008 | January 1, 2022 | |
| NCT00374595 | Completed | Vascular Risk After Kidney Transplantation | April 2006 | June 20, 2023 | |
| NCT00377312 | Completed | Early Phase 1 | 7 Day Continuous Parathyroid Hormone IV Infusion | September 2006 | December 2007 |
| NCT00379899 | Completed | Phase 4 | ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis | September 2006 | November 2009 |
| NCT00395902 | Completed | Post Transplant Study | August 2005 | ||
| NCT00417612 | Completed | Phase 3 | Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets | January 2007 | August 2012 |
| NCT00501215 | Completed | N/A | Effect of Parathyroidectomy on Sleep | May 25, 2007 | July 9, 2017 |
| NCT00513032 | Completed | Interaction Between Anaesthetics and Methylene Blue | January 2005 | April 2007 | |
| NCT00527267 | Completed | Phase 3 | Safety and Efficacy Study of AMG 073 in Hemodialysis Subjects | February 2002 | April 2003 |
| NCT00538720 | Completed | Phase 1 | Effects of Vitamin D Replacement in Patients With Primary Hyperparathyroidism (PHPT) | October 2007 | May 30, 2018 |
| NCT00580788 | Completed | Early Phase 1 | One Week Parathyroid Hormone-related Protein (PTHrP) IV Dose Escalation Study | January 2008 | December 2009 |
| NCT00744302 | Completed | Phase 2 | Study of 1.25 mmol/L Calcium Dialysate on Mineral Metabolism in Haemodialysis Patients. | April 2006 | December 2009 |
| NCT00800358 | Completed | N/A | Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism | November 2008 | December 2009 |
| NCT00887666 | Completed | Pilot Study: Hypovitaminosis D, Hyperparathyroidism and Hypomagnesemia in Patients With Congestive Heart Failure | October 2007 | October 2008 | |
| NCT00905866 | Completed | Quality of Life in Patients Undergoing Parathyroidectomy | August 2008 | July 2011 | |
| NCT00975000 | Completed | Phase 3 | Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant Recipients | December 3, 2009 | April 16, 2013 |
| NCT01042626 | Completed | N/A | Oral Peptones Load in Normocalcemic and Hypercalcemic Primary Hyperparathyroidism and Healthy Subjects | July 2004 | January 2005 |
| NCT01143987 | Completed | Phase 4 | Cincalcet and Vascular Arterial Stiffness Among Peritoneal Dialysis Patients With Secondary Hyperparathyroidism | June 2010 | February 2013 |
| NCT01163669 | Completed | A Prospective Cohort Study to Describe the Evolution of Persistent Hyperparathyroidism in Kidney Transplant Recipients | July 2010 | November 2012 | |
| NCT01191762 | Completed | Phase 3 | Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease | April 2010 | April 2013 |
| NCT05152927 | Recruiting | N/A | Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy | January 10, 2022 | January 31, 2025 |
| NCT00169806 | Recruiting | N/A | Randall's Plaque Study: Pathogenesis and Relationship to Nephrolithiasis | November 1998 | December 2025 |
| NCT05963841 | Recruiting | NUclear MEdicine DIagnostic and Artificial Intelligence | August 1, 2023 | August 2027 | |
| NCT05667090 | Recruiting | N/A | Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients | March 15, 2023 | December 31, 2027 |
| NCT05299632 | Recruiting | F-18 PSMA for Localization of Parathyroid Adenoma | March 31, 2022 | March 31, 2025 | |
| NCT01277510 | Terminated | Phase 3 | Pediatric Chronic Kidney Disease Safety and Efficacy | June 28, 2011 | |
| NCT03044600 | Terminated | Gene Expression in Hyperparathyroidism | November 7, 2012 | October 18, 2017 | |
| NCT03053999 | Unknown status | Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET) | October 9, 2012 | October 2023 | |
| NCT03203668 | Unknown status | N/A | 18F-fluorocholine PET/CT Imaging in Hyperparathyroidism | January 1, 2013 | December 31, 2020 |
| NCT05260255 | Unknown status | N/A | Effect of Vitamin D Supplement on Disease Activity in SLE | June 15, 2021 | December 1, 2022 |
| NCT04051099 | Unknown status | N/A | Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid Surgery | March 1, 2018 | December 15, 2021 |
| NCT01221896 | Unknown status | Input of C11-Choline PET/CT in Localization of Parathyroid Adenoma | January 2011 | ||
| NCT01226810 | Unknown status | The Novel Approach of Minimally Invasive Parathyroid Surgery Requires Precise Identification and Localization of the Lesion Prior to Exploration | January 2011 | ||
| NCT00452049 | Unknown status | The Effect of Parathyroidectomy on Renal Function, Endothelial Function, and Blood Pressure | April 2005 | ||
| NCT02986607 | Unknown status | Early Phase 1 | Corticosteroid Rhythms in Hypoparathyroid Patients | March 2016 | June 2018 |
| NCT00573573 | Unknown status | Phase 1 | Energy Specific Far Infrared Radiation Treatment for Hyperparathyroidism | January 2007 | July 2009 |
| NCT03973450 | Unknown status | Epidemiology of Pituitary Tumours: Prevalence of Associated Neoplasia | June 15, 2019 | February 28, 2022 | |
| NCT02711059 | Withdrawn | N/A | Insulin Resistance in Primary Hyperparathyroidism | October 2015 | June 2022 |
| NCT00359385 | Withdrawn | Phase 4 | The Effects of Alendronate After Cure of Primary Hyperparathyroidism | July 2006 | September 2009 |
| NCT01333267 | Withdrawn | Phase 1 | One Week Comparison Study of PTH and PTHrP Infusions | January 2015 | July 2017 |
- Disase is a (Disease Ontology)
- DOID:11201
- Cross Reference ID (Disease Ontology)
- ICD10CM:E21.3
- Cross Reference ID (Disease Ontology)
- ICD9CM:252.0
- Cross Reference ID (Disease Ontology)
- MESH:D006961
- Cross Reference ID (Disease Ontology)
- MIM:145000
- Cross Reference ID (Disease Ontology)
- MIM:145001
- Cross Reference ID (Disease Ontology)
- MIM:610071
- Cross Reference ID (Disease Ontology)
- NCI:C48259
- Cross Reference ID (Disease Ontology)
- ORDO:99879
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:190451000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0020502
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0000843
- OMIM Phenotype Series Number (OMIM)
- PS145000
- MedGen concept unique identifier (MedGen Concept name)
- C0020502
- MedGen unique identifier (MedGen Concept name)
- 6967
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006961