Annotation Detail

Information
Associated Genes
CCND1
Associated Variants
CCND1 MUTATION
CCND1 MUTATION
Associated Disease
B-Cell Lymphomas
Source Database
DisGeNET
Description
Mantle cell lymphoma (MCL) is a unique subtype of B-cell non-Hodgkin's lymphoma characterized by chromosomal translocation t(11;14)(q13;q32), positive CD5, and nuclear cyclin D1 overexpression with unfavorable prognosis.
Pubmed
24166616
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0203020585792303
Drugs