Annotation Detail
Information
- Associated Genes
- CCND1
- Associated Variants
-
CCND1 MUTATION
CCND1 MUTATION - Associated Disease
- Adenocarcinoma of lung (disorder)
- Source Database
- DisGeNET
- Description
- Furthermore, HMC-1 exosomes contain and transfer KIT protein, but not the c-KIT mRNA to A549 cells and subsequently activate KIT-SCF signal transduction, which increase cyclin D1 expression and accelerate the proliferation in the human lung adenocarcinoma cells.
- Pubmed
- 25311367
- Section of the abstract supporting the evidence
- METHODS AND RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs