Annotation Detail

Information
Associated Genes
CCND1
Associated Variants
CCND1 MUTATION
CCND1 MUTATION
Associated Disease
colorectal carcinoma
Source Database
DisGeNET
Description
The elevated expression of ATG4B was highly correlated with CCND1 expression, consistently supporting the notion that ATG4B might contribute to MTOR-CCND1 signaling for G 1/S phase transition in colorectal cancer cells.
Pubmed
24991826
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0168293960689788
Drugs