Basal Cell Nevus Syndrome

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Information
Disease name
Basal Cell Nevus Syndrome
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03467789 Active, not recruiting Phase 1 Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma October 1, 2018 September 1, 2024
NCT00957229 Completed Phase 2 To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS) August 2009 January 2014
NCT01556009 Completed Phase 2 Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas April 2012 December 2015
NCT02100371 Completed N/A Study of BMS-833923 in Two Specific Patients With Basal Cell Nevus Syndrome February 2014 May 2017
NCT02157623 Completed N/A Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome February 1, 2016 December 1, 2016
NCT02550678 Completed Phase 1/Phase 2 A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma September 2015 November 2017
NCT02762084 Completed Phase 2 Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients June 6, 2016 April 24, 2017
NCT00555633 Completed Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients October 2004 February 2006
NCT03703310 Completed Phase 3 Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome) February 19, 2019 December 28, 2020
NCT04416516 Completed Phase 2 Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor July 16, 2020 February 14, 2024
NCT06330324 Enrolling by invitation Reproductive Options in Inherited Skin Diseases January 1, 2024 September 1, 2026
NCT06330350 Recruiting Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling January 1, 2024 December 31, 2025
NCT05463757 Recruiting Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study November 1, 2021 December 2024
NCT04308395 Terminated Phase 3 Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome) June 3, 2020 July 14, 2021
NCT02303041 Terminated Phase 2 Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma February 2015 June 2017
NCT03767439 Withdrawn Phase 2 Nivolumab With Vismodegib in Patients With Basal Cell Nevus Syndrome July 2019 February 2020
MeSH unique ID (MeSH (Medical Subject Headings))
D001478