Clear-cell metastatic renal cell carcinoma

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Information
Disease name
Clear-cell metastatic renal cell carcinoma
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02978404 Active, not recruiting Phase 2 Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases June 2, 2017 December 31, 2023
NCT01521715 Completed Phase 4 First Line Pazopanib in Poor Risk Patients With Metastatic Renal Cell Carcinoma January 24, 2012 July 31, 2017
NCT01693822 Completed Phase 2 A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for Nephrectomy October 2012 February 28, 2022
NCT01715935 Completed Phase 2 Biomarkers Before and After Nephrectomy of Locally Advanced or Metastatic Renal Cell Carcinoma Treated With Everolimus June 2012 April 2016
NCT02228954 Completed IMaging PAtients for Cancer Drug selecTion - Renal Cell Carcinoma (IMPACT-RCC) December 2014 October 19, 2021
NCT01472081 Completed Phase 1 Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016) February 9, 2012 June 3, 2021
NCT05745142 Completed A Study to go Back Into Records and Observe How People With Metastatic Renal Cell Carcinoma (mRCC) Who Received a Medicine Called Sunitinib Responded to This Medicine. February 23, 2023 February 23, 2023
NCT02724020 Completed Phase 2 MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma June 30, 2016 October 13, 2020
NCT02917772 Completed Phase 2 Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Renal Cell Carcinoma October 2016 October 2022
NCT06279403 Not yet recruiting Phase 2 Upfront Immune Checkpoint Inhibitors With Deferred Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma March 1, 2024 March 1, 2029
NCT05263050 Recruiting Phase 2 Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma January 21, 2022 February 2027
NCT05567588 Recruiting Phase 2 Pembrolizumab Plus Radiotherapy for Advanced Renal Cancer October 31, 2022 October 31, 2025
NCT02543645 Terminated Phase 1 A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer October 2015 May 22, 2017
NCT02386111 Terminated Phase 1 A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell Carcinoma May 2015 November 3, 2017
NCT02535351 Terminated Phase 3 Targeted Therapy With or Without Nephrectomy in Metastatic Renal Cell Carcinoma: Liquid Biopsy for Biomarkers Discovery November 2015 September 28, 2018
NCT02570789 Terminated Phase 4 Evaluation of Predictive Markers for Toxicity and Efficacy in Patients With mccRCC Treated by Anti-VEGF Therapy December 2012 March 1, 2021
NCT02880943 Unknown status Phase 1/Phase 2 Dose-finding, Safety and Efficacy Study of Radium-223 Dichloride (XOFIGO) in RCC Patients With Bone Metastases. (EIFFEL) October 2016 February 2021