Annotation Detail

Information
Associated Genes
CCND1
Associated Variants
CCND1 MUTATION
CCND1 MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
AP-1 transcriptional activity was analyzed with a luciferase reporter and bioluminescence imaging, as well as qRT-PCR analysis of downstream target, cyclin D1, to determine the mechanism of action for DDX21 in breast tumorigenesis.
Pubmed
25260534
Section of the abstract supporting the evidence
METHODS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0464165601257319
Drugs