Annotation Detail
Information
- Associated Genes
- CCND1
- Associated Variants
-
CCND1 MUTATION
CCND1 MUTATION - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- We found that TBLR1 expression was implicated in the upregulation of cyclin D1, phosphorylation of cell-cycle control protein Rb (pRb) and activation of β-catenin signaling in breast cancer.
- Pubmed
- 25341494
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.105537482675749
Drugs